Search clinical trials for: High-dose

Total 11022 results

Vaxart

Completed

Phase 1 Placebo-controlled, Randomized Trial of an Adenoviral-vector Based Norovirus Vaccine

Norovirus Gastroenteritis

United States
Milton S. Hershey Medical Center

Completed

Influence of Selenium on Prostate Cancer Related Biomarkers

Effect of Selenium on Oxidative Stress in Healthy Men

United States
Medicago

Completed

Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal VLP Quadrivalent Influenza Vaccine in the Elderly Population

RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases

Canada
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Immunogenicity of the Human Cytomegalovirus Vaccine (V160) in Healthy Adults (V160-001)

Cytomegalovirus Infections
Santen Inc.

Completed

Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (SEE-1)

Ocular Hypertension | Open-angle Glaucoma

United States
Memorial Sloan Kettering Cancer Center

Withdrawn

Feasibility and Safety Study Using Preoperative High-Dose Single-Fraction Image-Guided Radiotherapy for Men Undergoing Radical Prostatectomy at High-Risk for Extraprostatic Cancer

Prostate Cancer

United States
Centre Antoine Lacassagne
Roche Pharma AG; Centre Hospitalier Universitaire de Caen

Recruiting

Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc) (Stereosarc)

Sarcoma | Radiosurgery

France
University of Oklahoma
Stephenson Cancer Center

Completed

High Dose Chemo With Autologous BMT for Treatment of Metastatic Breast Cancer

Breast Neoplasms

United States
Yale University

Completed

Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing IN Gammopathy Patients (SHIVERING 2)

Multiple Myeloma | Influenza | Waldenstrom's Macroglobulinemia | MGUS | Plasma Cell Disorders

United States
KBio Inc

Completed

KBP-201 COVID-19 Vaccine Trial in Healthy Volunteers

Covid19

United States, Canada
Penn State University
California Strawberry Commission

Completed

Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk

Cardiovascular Disease

United States
Nemysis Ltd
RDC Clinical Pty Ltd

Recruiting

Safety and Effectiveness of Iron Hydroxide Adipate Tartrate (IHAT) in Iron Deficient Premenopausal Women

Iron-deficiency

Australia
Medical University of South Carolina

Recruiting

Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE)

Systemic Lupus Erythematosus

United States
Ohio State University

Completed

A Pilot Study: High Versus Low Oxytocin Dosing for Induction of Labor in Pregnant Patients With Obesity (HILIO-PILOT)

Pregnant Patients With Obesity

United States
Helixmith Co., Ltd.

Completed

Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy

Painful Diabetic Neuropathies

United States, Korea, Republic of
Dong-A ST Co., Ltd.

Completed

Study to Evaluate the Efficacy and Safety of Intra-articular DA-5202 in Patients With Osteoarthritis of the Knee

Osteoarthritis, Knee

Korea, Republic of
Taiho Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety Study of TAS5315 Compared With Placebo in Participants With Rheumatoid Arthritis.

Rheumatoid Arthritis

Japan
Georgetown University

Unknown

Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Parkinson's Disease (PD Nilotinib)

Parkinson Disease | Parkinsons Disease With Dementia

United States
Access Business Group
Fudan University; Sprim Advanced Life Sciences; Sinphar Pharmaceutical Co., Ltd

Completed

Effect of Ginko and Cistanche Against Fatigue Symptoms (GkoCist)

Fatigue | Mental Fatigue | Chronic Fatigue Syndrome
Beijing Bozhiyin T&S Co., Ltd.

Unknown

To Evaluate the Efficacy and Safety of Wenxin Keli in Treating Atrial Premature Beats

Atrial Premature Beats

China
Braintree Laboratories

Completed

A Safety and Efficacy Evaluation of BLI801 Laxative in Constipated Adults

Constipation

United States
National Cardiovascular Center Harapan Kita Hospital...

Completed

Can Oral T3 Normalize Thyroid Hormone Levels Following Cardiopulmonary Bypass in Children?

Low T3 Syndrome

Indonesia
Radboud University Medical Center
Sanofi

Unknown

TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer (Condor)

Head and Neck Cancer

Netherlands
Lawson Health Research Institute
Academic Medical Organization of Southwestern Ontario

Recruiting

Hypofractionated External-beam RadiOtherapy for Intact Cervical Cancer (HEROICC-Trial): A Feasibility Study

Cervical Cancer

Canada
Inova Health Care Services

Completed

Standard-dose Versus High-dose Flu Vaccine in Solid Organ Transplant.

Influenza, Human | Transplantation Infection

United States
Duke University
National Institutes of Health (NIH)

Not yet recruiting

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA) (MICA)

Obesity | Pediatric Obesity | Asthma in Children | Pediatric Asthma

United States
Jiangsu Tasly Diyi Pharmaceutical Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of TSL-1502 Capsules in Breast Cancer Patients With Germline BRCA Mutations

Breast Cancer Metastatic

China
Novartis Pharmaceuticals

Completed

Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis

Moderate to Severe Chronic Plaque-type Psoriasis

Belgium, Spain, Russian Federation, Germany, United States, Czechia, Peru, Poland, Estonia
Inotrem

Active, not recruiting

Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock (ASTONISH)

Shock, Septic

Belgium, France, Spain, Denmark, Finland, Ireland
InQpharm Group

Completed

Benefit and Tolerability of IQP-LU-104 in Weight Loss

Obesity | Overweight

Germany
Rutgers, The State University of New Jersey
Vault Health, Inc.; Danisco USA Inc.

Completed

Live Microbials to Boost Anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Immunity Clinical Trial

Covid19

United States
Allergan
TARIS Biomedical, Inc.

Completed

Safety Study of LiRIS in Interstitial Cystitis (IC) Patients

Interstitial Cystitis

Canada
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Validation of a Treatment Algorithm for Poor-Risk NSGCTnon Seminomatous Germ-cell Tumors (VAPOR)

Non-Seminomatous Germ Cell Tumor

France
Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety, Tolerability and Pharmacokinetics of MIJ821 in Participants With Treatment- Resistant Depression (TRD)

Treatment-Resistant Depression

Spain, Japan, Poland, United States
Botanix Pharmaceuticals

Completed

A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Hyperhidrosis

United States
Oslo University Hospital
Eurocine Vaccines AB; Bionor Immuno AS

Completed

Intranasal Modified Vacc-4x Gag Peptides With Endocine as Adjuvant

HIV Infection

Norway
Tasly Pharmaceutical Group Co., Ltd

Unknown

Efficacy and Safety of Susu Zhike Granules for Treating Acute Cough Due to Common Cold With Cold-cough Syndrome in Children

Cough

China
Gilead Sciences

Not yet recruiting

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Sanofi Pasteur, a Sanofi Company
Sanofi K.K.

Completed

Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Patients ≥65 Years

Influenza

Japan
Boehringer Ingelheim

Completed

Relative Bioavailability of 1 mg and 10 mg BI 1356 BS as Powder in the Bottle (PIB) to 1 mg and 10 mg BI 1356 BS as Tablets as Single Oral Administration in Healthy Male Volunteers Including the Influence of Food on the Bioavailability of 10 mg BI 1356 BS

Healthy
MAXVAX Biotechnology Limited Liability Company
Henan Center for Disease Control and Prevention

Active, not recruiting

Safety and Immunogenicity of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 18 Years and Above

Herpes Zoster

China
Boehringer Ingelheim

Completed

Efficacy and Safety of Telmisartan and Losartan in Primary Hypertension

Hypertension
Boehringer Ingelheim

Completed

BIBR 277 Capsule in Patients With Essential Hypertension

Hypertension
Boehringer Ingelheim

Completed

BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid Tumours

Neoplasms

Canada
Yonsei University

Completed

Efficacy of Proton Pump Inhibitor for Chronic Cough Caused by Gastroesophageal Reflux; Double-blind, Placebo-controlled, Randomized Clinical Trial

Chronic Cough Caused by Gastroesophageal Reflux

Korea, Republic of
National Institute of Arthritis and Musculoskeletal...

Completed

High-Dose Intravenous (IV) Cyclophosphamide Versus Monthly IV Cyclophosphamide

Lupus Erythematosus, Systemic

United States
Damascus University

Completed

Effect of Laser Application in Pain Management Following the Use of Orthodontic Elastomeric Separators

Orthodontic Treatment

Syrian Arab Republic
University of Campinas, Brazil

Completed

Bone Graft Necessity in Opening-Wedge High Tibial Osteotomy

Osteoarthritis

Brazil
Kaiser Permanente
Seqirus

Recruiting

Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years

Influenza | Community-acquired Pneumonia | Cardiovascular Events

United States
Medipost Co Ltd.

Recruiting

Follow-up Safety and Efficacy Evaluation on Subjects Who Completed Phase I Clinical Trial

Knee Osteoarthritis

Korea, Republic of

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