Search clinical trials for: histamine-2 receptor antagonist

Total 13853 results

AstraZeneca
Parexel

Completed

A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine

Solid Tumours

United States
Handok Inc.
Takeda

Completed

Omnaris Versus Levocetirizine Phase 4 Study

Allergic Rhinitis

Korea, Republic of
Kocaeli University

Completed

Comparison of Efficacy Between Piracetam and Dimenhydrinate in Patients With Peripheral Vertigo

Peripheral Vertigo

Turkey
Bristol-Myers Squibb

Completed

Study to Assess the Effect of Acid-reducing Agent Famotidine on the Drug Levels of BMS-986256 in Healthy Participants

Healthy Participants

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Brompheniramine Maleate Liquid in Children and Adolescents

Allergic Reactions
University of California, San Francisco

Completed

Effect of Clemastine Fumarate on Color Vision in Healthy Controls

Healthy Subjects

United States
Sanofi

Recruiting

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

Pruritus

Poland, China, Spain, Italy, Japan, United States, Canada, France, Germany, Hungary, Korea, Republic of, Argentina
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab (LIBERTY-CSU CUPID)

Chronic Spontaneous Urticaria

China, France, Spain, Argentina, Germany, Japan, United States, Canada, Hungary, Russian Federation, United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Dupilumab for the Treatment of Chronic Inducible Cold Urticaria in Patients Who Remain Symptomatic Despite the Use of H1-antihistamine (LIBERTY-CINDU CUrIADS)

Cold Urticaria

United States, Argentina, Canada, Germany, Japan
Xian-Janssen Pharmaceutical Ltd.

Completed

A Study to Assess the Bioequivalence of Xisimin (Loratadine) Tablets Under Fasting and Fed Conditions in Healthy Participants Compared With Clarityne Tablets

Healthy

China
M.D. Anderson Cancer Center
Amgen

Terminated

Study of Loratadine for Pegfilgrastim Induced Bone Pain in Patients With Aggressive Lymphoma

Lymphoma

United States
Pfizer

Terminated

A Study To Investigate The Safety And Toleration Of Multiple Oral Doses Of PF-03654764 In Combination With Fexofenadine In Healthy Subjects

Healthy

Singapore
Pfizer

Completed

The Effect Of PF-03654764 +/- Allegra On Symptoms Of Allergic Rhinitis

Allergic Rhinitis

Canada
HK inno.N Corporation

Unknown

Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy

Perennial Allergic Rhinitis
Children's Mercy Hospital Kansas City

Active, not recruiting

Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia (Ketotifen)

Functional Dyspepsia

United States
Hospital San Carlos, Madrid

Terminated

Presurgery Anxiolysis in Children Treated With Hydroxyzine Versus Non-pharmacological Intervention (Distractoria Technique Clown) (SONRISA)

Anxiety

Spain
HealthPartners Institute
Park Nicollet Eating Disorder Institute

Withdrawn

Does Hydroxyzine Decrease Anxiety in Underweight Patients Diagnosed With an Eating Disorder

Anxiety in Those Patients With Anorexia Nervosa | Eating Disorder Not Otherwise Specified, BMI (<=18)

United States
ALK-Abelló A/S

Completed

Efficacy of SLITone in House Dust Mite Allergic Patients

Allergy

Spain
Aalborg University

Enrolling by invitation

Testing Protocol to Efficiently Induce Itch (ELIT)

Itch

Denmark
Organon and Co

Completed

Preference for Clarinex Tablets vs. Zyrtec Tablets in Patients With Allergies (P03181)

Perennial Allergic Rhinitis | Seasonal Allergic Rhinitis
Xian-Janssen Pharmaceutical Ltd.

Completed

A Study to Assess the Relative Bioavailability of Xisimin (Loratadine) Tablets Under Fasting and Fed Conditions in Healthy Participants Compared to Clarityne Tablets

Healthy

Taiwan
Sanofi

Completed

Study of Triamcinolone Acetonide on the Growth Velocity of Children, Ages 3 to 9, With Perennial Allergic Rhinitis (PAR)

Rhinitis, Allergic, Perennial

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Cetirizine HCl 10 mg Tablets Under Non-fasting Conditions

Healthy

United States
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Efficacy of Placebo Versus Chlorpheniramine for the Prevention of Allergic Transfusion Reactions.

Allergic Transfusion Reaction

China
Auburn University

Completed

First-generation OTC Antihistamine Use and Voice Function: A Preliminary Study

Voice Disorder Due to Iatrogenic Factor

United States
University Hospital, Bordeaux

Completed

Hemodynamic Instability Prevented With Polaramine® Infusion Before Extracorporeal Circulation (HIPPIE)

Hemodynamic Instability | Vasoplegic Syndrome

France
Medical College of Wisconsin

Terminated

Effects of Cyproheptadine on Growth and Behavior in Pediatric Feeding Disorders

Feeding Behaviors
Indira Gandhi Medical College, Shimla

Completed

Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis

Allergic Rhinitis
Sanofi

Completed

Long-Term Safety Performance of Fexofenadine in Asthma

Asthma

United States
Bayer

Completed

A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic Rhinitis (P08712)

Rhinitis
Charite University, Berlin, Germany
Hospital del Mar

Completed

Study to Assess Efficacy, Safety and Mechanism of Rupatadine in Cold Urticaria (PAFCUTIII)

Cold Contact Urticaria

Germany
Organon and Co

Completed

Study for the Treatment of Chronic Idiopathic Urticaria With High Doses of AERIUS (Desloratadine) (Study P04849)

Chronic Idiopathic Urticaria
Organon and Co

Completed

The Duration of the Suppressive Effects of Desloratadine on Allergen Prick Tests After Discontinuation (P04441)

Hypersensitivity
Perrigo Company

Completed

Bioequivalence Study Between Two Oral Formulations of Famotidine Tablets Under Fed Conditions

Bioavailability
Prof. Dominique de Quervain, MD
Clinical Trial Unit, University Hospital Basel, Switzerland

Completed

Influence of Losartan and Diphenhydramine on Emotional and Cognitive Functions in Healthy Human Subjects (LoDi-Basel)

Memory, Short-Term | Memory, Long-Term

Switzerland
Reema Padia

Active, not recruiting

Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia

Gastro Esophageal Reflux | Laryngomalacia

United States
Bristol-Myers Squibb

Completed

A Study to Determine the Effect of Famotidine on the Drug Levels of BMS-986256 in Healthy Participants

Healthy Participants

United States
King Faisal Specialist Hospital & Research Center

Completed

Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size

Placebo Effect | Placebo Drug Interaction

Saudi Arabia
Ranbaxy Laboratories Limited

Completed

A Relative Bioavailability Study of 20 mg Famotidine Tablets Under Fasting Condition

Healthy

India
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Completed

Treatment of Adolescent Suicide Attempters (TASA)

Depression | Suicide, Attempted

United States
Organon and Co

Completed

Preference for Clarinex Tablets vs. Zyrtec Tablets in Patients With Allergies (P03182)

Perennial Allergic Rhinitis | Seasonal Allergic Rhinitis
Chong Kun Dang Pharmaceutical

Completed

Clinical Trial to Evaluate the Efficacy and Safety of CKD-342

Rhinitis, Allergic, Perennial

Korea, Republic of
Pfizer

Terminated

A Study of the Safety, Tolerability, Pharmacokinetics, And Effects On Histamine-Induced Wheal Of PF-05180999 In Healthy Adults

Migraine

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension (REHAB-PH)

Pulmonary Arterial Hypertension | Right Heart Failure

United States
Perrigo Company

Completed

Bioequivalence Study Between Two Oral Formulations of Famotidine Tablets Under Fasting Conditions

Bioavailability
National Institute on Deafness and Other Communication...

Completed

Acute Otitis Media: Adjuvant Therapy to Improve Outcome

Otitis Media

United States
Hanmi Pharmaceutical Company Limited

Completed

PK and Safety Study of HCP1102, HGP0813 and HGP1408

Healthy

Korea, Republic of
University of California, San Francisco
Food and Drug Administration (FDA)

Recruiting

Excipient Effect on Drug Absorption in Humans

The Impact of Excipients on Drug Absorption

United States
NVT GmbH

Active, not recruiting

Investigation of the ALLEGRA THV System With a New Delivery System in Patients With Aortic Stenosis or Failed Surgical Bioprosthesis (EMPIRE)

Transcatheter Aortic Valve Implantation

Germany, Spain
Charite University, Berlin, Germany

Completed

Safety Study of Levocetirizine and Fexofenadine (LAWAF)

Allergic Rhinitis | Pruritus | Chronic Urticaria

Germany

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