Search clinical trials for: human insulin as nasal spray

Total 951 results

Halozyme Therapeutics

Completed

Dose-Ranging, Pharmacokinetic (PK), Glucodynamic (GD), Safety and Tolerability Study of Subcutaneously (SC) Administered Humulin R and Humalog With or Without rHuPH20

Healthy Volunteers

United States
Marcus Saemann

Completed

Treat-to-target Trial of Basal Insulin in Post-transplant Hyperglycemia (TIP)

Hyperglycemia

Austria
Mayo Clinic

Completed

Treatment Trial Evaluating Long Acting Insulin in Type 1 Diabetes

Type 1 Diabetes

United States
University of Campania "Luigi Vanvitelli"

Completed

Durability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND) (BEYOND)

Type 2 Diabetes

Italy
University of Missouri-Columbia

Recruiting

Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation

Healthy | Obesity | Insulin Resistance | Vasodilation | Autonomic Dysfunction

United States
Jinnah Postgraduate Medical Centre

Completed

Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.

ATROPHIC ACNE SCARS

Pakistan
Amphastar Pharmaceuticals, Inc.

Completed

Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers

Pharmacokinetics | Pharmacodynamics

United States
Eli Lilly and Company

Completed

A Study for Patients With Diabetes Mellitus (IOPA) (IOPA)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

China
Baylor College of Medicine

Completed

The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients (GIH)

Hyperglycemia | Diabetes Mellitus

United States
Upsher-Smith Laboratories

Completed

An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg)

Migraine Headaches

United States
Eli Lilly and Company

Completed

A Study of Basal Insulin Analog and Insulin Analog Mid Mixture in Chinese Participants With Type 2 Diabetes Mellitus (CLASSIC)

Type 2 Diabetes Mellitus

China
Adocia

Completed

A Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes

Diabetes Mellitus Type 1

Germany
Mannkind Corporation

Completed

Healthy Normal Volunteers Looking at Exposure and Effects of Multiple Doses of Technosphere® Insulin (TI) Using the Gen2C Inhaler

Healthy

United States
Eli Lilly and Company

Withdrawn

A Study of A Novel Approach to Titrate Basal Insulin (LY2963016) in Participants With Type 2 Diabetes

Type 2 Diabetes | Type 2 Diabetes Treated With Insulin

United States
Clinical Research Centre, Malaysia
Medtronic

Unknown

Improving Glycaemic Control in Malaysian Patients With Type 2 Diabetes Mellitus With Insulin Pump Therapy

Type 2 Diabetes Mellitus

Malaysia
University Hospital, Bonn

Completed

Dissecting the Role of Estradiol in Mediating Gender-specific Anxiolytic and Prosocial Effects of Oxytocin (ESMory)

Oxytocin | Memory | Estrogen | Fear Extinction | Emotion Processing

Germany
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
GlaxoSmithKline

Completed

Phase 4 Fluticasone Furoate Nasal Spray (VERAMYST) Long Term Pediatric Growth Study.

Rhinitis, Allergic, Perennial

United States, Argentina, Canada, France, Peru, Italy, Chile
Halozyme Therapeutics

Completed

Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Participants With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

United States
Novo Nordisk A/S

Terminated

Effect of Inhaled Insulin (AERx® iDMS) on Blood Glucose Control in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

United States
HealthPartners Institute
Sanofi; International Diabetes Center at Park Nicollet

Completed

Hospital Insulin Protocol Aims for Glucose Control in Corticosteroid-induced Hyperglycemia

Hyperglycemia

United States
Acorda Therapeutics

Completed

A Pharmacokinetic Study to Assess Dose Proportionality, Safety and Tolerability of Diazepam Nasal Spray in Healthy Adult Volunteers

Healthy

United States
Eli Lilly and Company

Completed

A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-2)

Diabetes | Type 2 Diabetes

United States, China, Germany, Mexico, Brazil, Canada, Japan, Korea, Republic of, Puerto Rico, Czechia, Greece
Hospices Civils de Lyon

Completed

Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO) (TEMPO)

Telangiectasia, Hereditary Hemorrhagic | Osler Rendu Disease

France
Linmarie Sikich
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors (SOARS-B)

Autism Spectrum Disorders

United States
Pontificia Universidade Católica do Rio Grande...
Conselho Nacional de Desenvolvimento Científico e Tecnológico; Secretaria Nacional...

Unknown

Use of Intranasal Oxytocin During Detoxification of Crack Cocaine

Cocaine-Related Disorders | Cocaine Withdrawal | Cocaine Smoking

Brazil
Meda Pharmaceuticals

Completed

3 Month Safety Study of Dymista Nasal Spray and Fluticasone Propionate in Children 4-11 Years of Age With Allergic Rhinitis

Allergic Rhinitis

United States
Emory University
Novo Nordisk A/S

Completed

Insulin Detemir Versus NPH Insulin In Hospitalized Patients With Diabetes (DEAN)

Type 2 Diabetes

United States
US Department of Veterans Affairs

Completed

Insulin Secretion in Diabetes Before and After Glycemic Control

Hyperglycemia | Diabetes

United States
Medical University Innsbruck

Withdrawn

ECT vs. Esketamine (ETES)

Major Depressive Disorder | Treatment Resistant Depression

Austria
Dance Biopharm Inc.
WCCT Global

Terminated

PK and PD Profile of Dance 501 in Healthy, Non-diabetic Subjects With Mild to Moderate Asthma or COPD

Safety and Tolerability

United States
University of Surrey
Novo Nordisk A/S

Completed

Detemir Energy Expenditure Study (DEES)

Obesity | Type 2 Diabetes Mellitus

United Kingdom
Vancouver General Hospital

Terminated

Insulin Therapy for Post-transplant Glucocorticoid Induced Hyperglycemia (PTHG)

Post-Transplant Glucocorticoid Induced Diabetes

Canada
Genesys
Novo Nordisk A/S

Completed

The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit

Sepsis | Respiratory Failure | Renal Failure | Surgical Site Infection

United States
Mannkind Corporation

Completed

Afrezza With Basal Combination (ABC)

Type 1 Diabetes

United States
Novo Nordisk A/S

Completed

Safety and Efficacy of Insulin NPH Compared to a New Insulin Formulation in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Brazil
Eli Lilly and Company

Completed

A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections (QWINT-4)

Type 2 Diabetes | Type 2 Diabetes Treated With Insulin

United States, Germany, Mexico, Argentina, Puerto Rico, Italy, Spain, India
University of Sao Paulo General Hospital

Completed

Glargine Versus NPH in Patients With Chronic Kidney Disease

Type 2 Diabetes Mellitus | Chronic Kidney Disease

Brazil
Medical University of South Carolina

Completed

IV Insulin Protocol in Diabetes and Renal Transplantation

Hyperglycemia | Diabetes | Kidney Transplantation

United States
Region Örebro County
Uppsala-Örebro Regional Research Council

Completed

Treatment of Impaired Glucose Tolerance in Pregnancy (TIP)

Impaired Glucose Tolerance | Fetal Macrosomia

Sweden
Laboratoire de la Mer
EVAMED

Completed

Seawater Nasal Wash to Relieve COVID-19 Nasal Symptoms and Reduce SARS-CoV-2 Viral Load. (SeaCare)

SARS-CoV2 Infection (COVID-19) | URTI - Viral Upper Respiratory Tract Infection

France
Eli Lilly and Company

Active, not recruiting

A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-1) (QWINT-1)

Type 2 Diabetes | T2D

United States, Mexico, Argentina, Puerto Rico
Amalgam Rx, Inc.

Completed

A Digital Health Tool for Insulin Titration (DHIT) Individuals With Type 2 Diabetes: A Prospective Outcomes Study With a Retrospective Control Group (DHIT)

Diabetes Mellitus, Type 2

United States
Sanofi

Completed

Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents

Diabetes Mellitus

United States
Karolinska Institutet

Completed

Long-term Effects of Intensive Insulin Treatment in Type 1 Diabetes (SDIS)

Stroke | Renal Failure | Coronary Heart Disease

Sweden
Humacyte, Inc.
California Institute for Regenerative Medicine (CIRM); CTI Clinical Trial and...

Completed

Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis

Renal Failure | Hemodialysis | End Stage Renal Disease | Vascular Access

United States, Israel, United Kingdom, Portugal, Poland, Germany
Eli Lilly and Company

Completed

Local Registration Trial in China Humalog Mix 50

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

China
ORA, Inc.

Completed

An Allergen BioCube (ABC) Study Evaluating the Efficacy of Fluticasone Propionate Nasal Spray Compared to Placebo

Allergic Rhinitis | Allergic Conjunctivitis

United States
King Faisal Specialist Hospital & Research Center

Completed

Glargine Insulin vs.Continuous Regular Insulin in Diabetic Surgical Patients Receiving Parenteral Nutrition (GLUCOSE-in-PN) (GLUCOSE-in-PN)

Diabetic Patients With Gastrointestinal Cancer Undergoing Surgery and Receiving Parenteral Nutrition

Saudi Arabia
German Diabetes Center

Completed

The Effect of Central Insulin on Insulin Sensitivity and Energy Metabolism (Centrin)

Diabetes

Germany

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