Search clinical trials for: hydrochlorothiazide, losartan

Total 759 results

Chong-Jin Kim
Hanmi Pharmaceutical Company Limited

Completed

Comparison of Effects Between Amlodipine and Hydrochlorothiazide in Combination With Losartan on 24-hr Central Blood Pressure in Hypertensive Patients

Hypertension

Korea, Republic of
University Hospital, Strasbourg, France

Suspended

Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria

Hypertension | End Stage Renal Disease | Proteinuria

France
Organon and Co

Completed

Antihypertensive Efficacy and Safety of Approved Drugs in Japanese Patients With Essential Hypertension (Banyu Study)(0954A-302)

Hypertension
Organon and Co

Completed

Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306)

Hypertension
Organon and Co

Terminated

A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)

Hypertension
University of Cambridge
British Heart Foundation

Unknown

Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension (Pathway 1)

Essential Hypertension | Hypertension, Resistant to Conventional Therapy

United Kingdom
Teva Pharmaceuticals USA

Completed

Losartan Potassium/Hydrochlorothiazide 100/25 mg Tablets in Healthy Subjects Under Fasting Conditions

Healthy

United States
EMS

Suspended

Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension Treatment

Hypertension

Brazil
Boehringer Ingelheim

Completed

PROBE Parallel 6-week Treatment Comparing Telmisartan/Hydrochlorothiazide (HCT) (40/12.5 or 80/12.5) With Losartan/HCT (50/12.5) Using Ambulatory Blood Pressure Monitoring (ABPM)

Hypertension

United States
Azidus Brasil

Completed

Clinical Assessment Of Association Pharmacokinetics Atorvastatin + Losartana + Hydrochlorothiazide

Healthy Subjects

Brazil
Organon and Co

Completed

BP-EASE -Effectiveness of Losartan 50 mg/Hydrochlorothiazide (HCTZ) 12.5 mg Versus Valsartan 80 mg/HCTZ 12.5 mg Titrated as Needed in Patients With Essential Hypertension Not Controlled on Monotherapy (0954A-333) (EASE)

Hypertension
The University of The West Indies
Caribbean College of Family Physicians

Withdrawn

Phase 4 Study of the Efficacy of Losartan Based Therapy in Hypertensives With and Without Diabetes

Hypertension | Diabetes Mellitus

Jamaica
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Olmesartan Medoxomil Versus Losartan in Elderly and Very Elderly

Essential Hypertension

Germany
Boehringer Ingelheim

Completed

A Randomized, Double-blind, Parallel-group Assessment of the Safety and Efficacy of Telmisartan 40mg Plus Hydrochlorothiazide 12.5mg (Micardis Plus) in Comparison With Losartan 50mg Plus Hydrochlorothiazide 12.5mg in Taiwanese Patients With Mild to Moderate Hypertension

Hypertension

Taiwan
Organon and Co

Completed

MK0954A-264 Filter Study (0954A-264)(COMPLETED)

Mild to Severe Hypertension
Damanhour University

Completed

Pharmacokinetic Interactions of Losartan and Hydrochlorothiazide (PKLH)

Healthy Normotensive Participants
Merck Sharp & Dohme LLC

Completed

Hyzaar Asia HEAALTH (0954A-950)

Hypertension
Laboratorios Silanes S.A. de C.V.

Completed

Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension

Essential Arterial Hypertension

Mexico
Roxane Laboratories

Completed

Bioequivalency Study of Losartan Potassium/Hydrochlorothiazide 100 mg /25 mg Tablet Under Fed Conditions

Hypertension

United States
Sir Mortimer B. Davis - Jewish General Hospital
Merck Frosst Canada Ltd.

Terminated

Losartan Versus Hydrochlorothiazide in Reversing Remodeling of Small Arteries in Pre-Hypertensive Pre-Diabetic Subjects

Pre-diabetes | Pre-hypertension

Canada
Boehringer Ingelheim

Completed

Telmisartan Compared to Losartan + Hydrochlorothiazide in Patients With Mild-to-moderate Essential Hypertension

Hypertension
Kurume University

Completed

Morning Hypertension and Preminent Therapy Study

Hypertension

Japan
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Losartan Potassium and Hydrochlorothiazide (100 mg / 25 mg Tablet) [Test Formulation, Torrent Pharmaceuticals Ltd., India] Versus Hyzaar® (100 mg / 25 mg Tablet) [Reference Formulation, Merck & Co., Inc., USA] in Healthy Human Volunteers Under Fasting Conditions.

Healthy
Teva Pharmaceuticals USA

Completed

Losartan Potassium/Hydrochlorothiazide 100/25 mg Tablets in Healthy Subjects Under Non-Fasting Conditions

Healthy

United States
Organon and Co

Completed

A 52 Week Study to Evaluate the Effects of Losartan With or Without HCTZ on Plasma Glucose, Metabolic Parameters, Blood Pressure in Hypertensive Patients With Metabolic Syndrome (0954A-331)

Hypertension | Metabolic Disorder
Organon and Co

Completed

Evaluation of the Antihypertensive Effect of Hyzaar(R) and Cognitive Function of Hypertensive Patients (0954A-322)

Hypertension
Roxane Laboratories

Completed

Bioequivalency Study of Losartan Potassium/Hydrochlorothiazide 100 mg/25 mg Tablet Under Fasted Conditions

Hypertension

United States
Merck Sharp & Dohme LLC

Completed

Antihypertensive Response to Losartan and Genetic Polymorphisms

Hypertension
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Magnitude and Duration of Response of MK0954 Compared to Placebo in Patients With Hypertension (0954-021)(COMPLETED)

Hypertension
Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of a Single-pill Fixed Combination of Sufficient Losartan/Hydrochlorothiazide in Chinese Hypertensive Patients

Hypertension

China
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Losartan Potassium and Hydrochlorothiazide (100 mg / 25 mg Tablet) [Test Formulation, Torrent Pharmaceuticals Ltd., India] Versus Hyzaar® (100 mg / 25 mg Tablet) [Reference Formulation, Merck & Co., Inc., USA] in Healthy Human Volunteers Under Fed Conditions

Healthy

India
Kyushu University

Completed

Combination Pill of Losartan Potassium and Hydrochlorothiazide for Improvement of Medication Compliance Trial (COMFORT)

Hypertension

Japan
Organon and Co

Completed

Evaluate the Safety and Anti-Hypertensive Efficacy of Hyzaar(R) In Patients With Mild To Moderate Essential Hypertension (0954A-323)

Hypertension
Abbott

Completed

Tarka vs. Hyzaar in Patients With Metabolic Syndrome (STAR) (STAR)

Hypertension | Metabolic Syndrome
Hanmi Pharmaceutical Company Limited

Completed

Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease

Hypertension | Aortic Stenosis | Aortic Regurgitation | Left Ventricular Hypertrophy | LVM

Korea, Republic of
Yokohama City University Medical Center

Completed

Kanagawa Combination Anti-hypertensive Therapy (K-CAT)

Hypertension

Japan
Organon and Co

Completed

Hydrochlorothiazide (+) Losartan Potassium vs. Amlodipine Comparative Study (0954A-314)

Essential Hypertension
EMS

Withdrawn

Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension Control

Essential Arterial Hypertension
Organon and Co

Completed

LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED)

Hypertension
Merck Sharp & Dohme LLC

Completed

MK-0954E Study in Participants With Hypertension (MK-0954E-357)

Hypertension
EMS

Withdrawn

Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control

Essential Arterial Hypertension
Hotel Dieu de France Hospital

Unknown

Fixed-Free HTN Trial

Hypertension

Lebanon
Shanghai WiseGain Medical Devices Co., Ltd.

Unknown

Randomized Controlled Trial of Renal Denervation for Resistant Hypertension

Hypertension

China
Organon and Co

Completed

HYZAAR vs. Ramipril for Diabetes (0954A-245)(COMPLETED)

Hypertension | Type 2 Diabetes Mellitus
Columbia University

Completed

N-of-1 Trials for Blood Pressure Medications in Adults

Hypertension | High Blood Pressure

United States
Novartis

Completed

Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Therapy in Patients With Hypertension

Hypertension

United States
Baker Heart and Diabetes Institute

Withdrawn

Study of High Dosage of Losartan in Comparison to Low Dose of Losartan in Heart Failure Patients

Heart Failure
Organon and Co

Completed

SAALT: Subtracting Salt and Adding Losartan Trial (0954A-335)

Hypertension
Organon and Co

Completed

Study to Evaluate Potential Decrease in Hospitalization Events, Time Between Events, and Increasing Longevity in Patients With Symptomatic Heart Failure (0954-948)

Heart Failure
National Institute of Diabetes and Digestive and...
Johns Hopkins University

Terminated

Losartan for the Treatment of Pediatric NAFLD (STOP-NAFLD)

NAFLD - Nonalcoholic Fatty Liver Disease

United States

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