Search clinical trials for: Intranasal ketamine

Total 1842 results

Oman Medical Speciality Board

Completed

Atomized Intranasal Vs Intravenous Ketorolac in Acute Renal Colic Pain Management. (Ink-Arc)

Acute Renal Colic

Oman
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Safety, Pharmacokinetics and Pharmacodynamics of Intranasal Dexmedetomidine in Healthy Subjects

Sedation

China
Janssen Research & Development, LLC

Completed

A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant Depression (SUSTAIN-3)

Depressive Disorder, Treatment-Resistant

United States, France, Poland, United Kingdom, Belgium, Germany, Taiwan, Spain, Argentina, Mexico, Bulgaria, Malaysia, South Africa, Turkey, Canada, Korea, Republic of, Brazil, Estonia, Hungary, Lithuania, Slovakia, Sweden, Czechia, A... and more
University of Sao Paulo General Hospital

Recruiting

Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia.

Awakening, Post-Anesthesia Delayed

Brazil
Massachusetts General Hospital

Completed

Probiotics and Oxytocin Nasal Spray on Social Behaviors of Autism Spectrum Disorder (ASD) Children

Autism Spectrum Disorder

United States
University of Rochester
National Institutes of Health (NIH)

Completed

Effects of Age on Response to the 2009 H1N1 Virus Vaccine

2009 H1N1 Influenza Virus

United States
Lukas Pezawas

Recruiting

Add-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine Spray (Esketamin+)

Major Depressive Disorder | Therapy Resistant Depression

Austria
Janssen Research & Development, LLC

Completed

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

Major Depressive Disorder

United States
Ain Shams University

Recruiting

Efficacy of Preventive Ketamine on Postoperative Pain

Postoperative Pain

Egypt
Hospital for Special Surgery, New York

Terminated

Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome

Complex Regional Pain Syndrome

United States
Assiut University

Completed

Local Ketamine Instillation for Postoperative Analgesia

Postoperative Pain
Centre Hospitalier Universitaire de Nice

Completed

Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults

Fracture | Dislocation

France
Ibaraki Children's Hospital

Completed

Does Ketamine Attenuate Depression of Respiratory and Cardiac Functions

Congenital Heart Disease | Sedated for Cardiac Catheterization

Japan
Eli Lilly and Company

Recruiting

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk (ACHIEVE-4)

Cardiovascular Diseases | Obesity | Overweight | Type 2 Diabetes | Chronic Kidney Disease | Overweight or Obesity

United States, Italy, Spain, Korea, Republic of, India, Turkey, Austria, Puerto Rico, Mexico, Romania, Brazil, Germany, Argentina, Czechia, Greece, Slovakia
University of North Carolina, Chapel Hill

Completed

Oxytocin Treatment of Schizophrenia (OTS)

Schizophrenia | Schizoaffective Disorder | Paranoia

United States
Mercy Health Ohio

Terminated

Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain

Pain, Acute

United States
Massachusetts General Hospital
American Foundation for Suicide Prevention

Recruiting

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Major Depressive Disorder

United States
University of California, San Francisco

Completed

Effect of Betaine and Food on Gastric pH

Healthy

United States
Royal North Shore Hospital
Janssen-Cilag Pty Ltd

Recruiting

Positioning of Esketamine Treatment in the Real-world Management of Depression (PoET)

Major Depressive Disorder

Australia
Wuhan Union Hospital, China

Recruiting

Immunoinflammatory Regulation of Esketamine in Septic Patients

Sepsis | Inflammatory Response | Immunosuppression | Esketamine

China
PETHEMA Foundation

Completed

Meropenem Versus Meropenem Plus Glycopeptide in Patients With Febrile Neutropenia After Allogenic Blood Stem Cell Transplantation (MERONEM)

Febrile Neutropenia | Allogenic Blood Stem Cell Transplantation

Spain
Memorial Sloan Kettering Cancer Center

Completed

Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation

Hematologic Malignancies | Streptococcal Sepsis

United States
Zhuan Zhang

Completed

Effect of Subanesthetic Dose of Esketamine on Sleep Quality and Recovery of Gastrointestinal Function in Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery in the Early Postoperative Period

Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery

China
Medical University Innsbruck

Withdrawn

ECT vs. Esketamine (ETES)

Major Depressive Disorder | Treatment Resistant Depression

Austria
Janssen Research & Development, LLC

Completed

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly and and Healthy Younger Adult Participants

Healthy

Belgium
Naveen Poonai

Recruiting

Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation (Ketodex)

Fracture | Dislocation

Canada
Universiti Kebangsaan Malaysia Medical Centre

Completed

PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery

Ketamine | Morphine

Malaysia
National University of Malaysia

Completed

PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery.

Ketamine | Morphine

Malaysia
Children's Hospital Medical Center, Cincinnati

Completed

Pharmacokinetic Study of Dexmedetomidine After Intra-nasal Dosing in Children

Heart Disease

United States
Association Asthma, Bulgaria
Nasaleze

Unknown

4"S" - Seasonal Symptoms Suppression Study (4"S")

Seasonal Allergic Rhinitis

Bulgaria
University of Pennsylvania
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Alternative Sedation During Bronchoscopy (DEX)

Sedation

United States
Peking University First Hospital

Completed

Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Postoperative Analgesia

Dexmedetomidine | Postoperative Analgesia | S-ketamine | Sufentanil | Scoliosis Correction

China
Hannover Medical School

Completed

Topical Anesthesia / Bronchoscopy (TNA)

Equally of Delivery Systems of Local Anesthesia in Bronchoscopy

Germany
Shalvata Mental Health Center

Recruiting

The Effects of Oxytocin Administration to Patients and Therapists on Physiological Synchronization

Severe Mental Illness

Israel
Yangzhou University

Not yet recruiting

Application of Different Modes of Esketamine Administration in Pediatric Day Circumcision

Pain
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Inhaled Oxytocin and HPA Axis Reactivity

Anxiety Disorders | Stress, Psychological | Depression, Postpartum

United States
University Hospital, Basel, Switzerland

Completed

Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine

Pain

Switzerland
Air Force Military Medical University, China

Not yet recruiting

ED50 of Esketamine for Laser Treatment in Children (ESCALATE)

Anesthesia
Johns Hopkins University
United States Department of Defense; Congressionally Directed Medical Research...

Terminated

RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain

Acute Pain | Posttraumatic Stress Disorder | Wound Care

United States
Makerere University

Completed

Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers (KEM-VOC)

Acute Pain | Sickle Cell Crisis

Uganda
Universidade Federal de Goias
King's College London; University of Sao Paulo

Recruiting

Sedation Versus Protective Stabilization for Pediatric Dental Treatment

Dental Caries in Children | Child Behavior

Brazil
Universidade Federal de Santa Maria
Hospital de Clinicas de Porto Alegre; Santa Casa de Misericórdia de Belo Horizonte

Completed

Methadone and Ketamine for Neuropathic Pain Treatment

Neuropathic Pain

Brazil
Meyer Children's Hospital
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Azienda Ospedaliera Universitaria... and other collaborators

Terminated

Ketamine in Refractory Convulsive Status Epilepticus (KETASER01)

Status Epilepticus

Italy
Udayana University

Completed

Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy (PRO-Ketamine)

Inflammation | General Anesthesia | Laparotomy

Indonesia
Ullevaal University Hospital
University of Oslo

Terminated

Reversal of Ketamine Pharmacodynamic Effects With Naloxone

Pain

Norway
Centre for Addiction and Mental Health

Recruiting

Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia

Healthy | Schizophrenia

Canada
Caregen Co. Ltd.

Not yet recruiting

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics in Healthy Volunteers of the Novel Self-Administered Intranasal CG- SpikeDown Antiviral Drug

Healthy
Cairo University

Completed

Lidocaine-Ketamine Versus Ketamine for Induction of Anesthesia in Septic Shock Patients

Septic Shock

Egypt
Second Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Effect of Esketamine on 95% Induction Dose of Remimazolam (EEIDR)

Sedation | Pediatric | Gastroscopy | ED95

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Antibiotic Use in Reducing Vancomycin-Resistant Enterococci and ESBL Producing Escherichia Coli and Klebsiella Pneumoniae in Intensive Care

Klebsiella Infections | Escherichia Coli Infections

Korea, Republic of

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