Search clinical trials for: lidocaine, epinephrine (Local anesthetic)

Total 5344 results

Cairo University

Completed

Local and Intravenous Dexamethasone on Post Operative Pain a After CS

Postoperative Pain
Yun-fei Xia

Unknown

Efficacy and Safety of FORRAD® for the Management of Radiation-induced Mucositis in Patients With Nasopharyngeal Carcinoma Receiving IMRT

Nasopharyngeal Neoplasms | Stomatitis

China
Pfizer

Completed

Study To Assess The Effect Of Gabapentin, Diphenhydramine And Morphine On Cold Pain In Healthy Male Volunteers

Healthy

Belgium
Pfizer

Completed

A Study Of AG-013736 (Axitinib) Or Bevacizumab (Avastin) In Combination With Paclitaxel And Carboplatin In Patients With Advanced Lung Cancer.

Adenocarcinoma | Non-Small-Cell Lung Carcinoma

United States, Spain, Poland, Czech Republic, United Kingdom, France
Yale University
Department of Anesthesiology Faculty Development Fund

Recruiting

Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2 (Yale SEVEN)

Knee Arthroplasty | Total Knee Replacement

United States
Overseas Pharmaceuticals, Ltd.
Guangzhou Kangqi Medical Technology Co., LTD

Not yet recruiting

Comparative Pharmacokinetic (PK) Study of Ibuprofen and Diphenhydramine Hydrochloride MR Tablets in Healthy Adults Under Fasting Condition

Pain | Insomnia

China
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure

AML | MDS

United States
Hoffmann-La Roche

Active, not recruiting

A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy (MAJESTY)

Primary Membranous Nephropathy

United States, China, Spain, Argentina, Brazil, France, Italy, Russian Federation, Israel, Poland, Turkey, Ukraine
Hoffmann-La Roche

Active, not recruiting

A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis (REGENCY)

Lupus Nephritis

United States, Italy, Argentina, Germany, Colombia, South Africa, Poland, United Kingdom, Russian Federation, Brazil, France, Peru, Spain, Israel, Mexico
National Cancer Institute (NCI)

Completed

Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)

Urinary Bladder Neoplasms

United States
Tribhuvan University Teaching Hospital, Institute...

Completed

Comparison Of Dexmedetomidine And Dexamethasone As An Adjuvant To Bupivacaine In Brachial Plexus Block

Dexmedetomidine | Brachial Plexus Block | Dexamethasone | Bupivacaine

Nepal
Loma Linda University

Withdrawn

Adductor Canal Nerve Block Following Total Knee Arthroplasty

Post-op Pain

United States
Bayer

Completed

A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects Under Fed Conditions

Clinical Pharmacology

United States
Charleston Laboratories, Inc

Completed

Phase III Study of the Safety and Efficacy of Cl-108 in the Treatment of Moderate to Severe Pain

Pain | Nausea | Vomiting

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Randomized Trial of the Effectiveness of Topical "ABH Gel" vs. Placebo in Cancer Patients With Nausea

Nausea | Vomiting

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Alcohol-Related Disorders | Alcohol Use | Alcohol Use Disorder (AUD)

United States
Sultan Abdulhamid Han Training and Research Hospital...

Recruiting

Investigation of the Effect of Central Sensitization (CS) on Steroid Injection Response in Rotator Cuff Lesion (CS)

Subacromial Impingement Syndrome | Central Sensitisation

Turkey
Hoffmann-La Roche

Completed

A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.

Acute Myeloid Leukemia

Australia, Italy, Canada, United Kingdom, United States, Denmark, Spain, Taiwan, Germany, France
Cairo University

Completed

Analgesic Efficacy of Sequential Rapid Versus Slow Intrathecal Injection Of Dexmedetomidine Followed by of Hyperbaric Bupivacaine in Inguinal Hernia Repair Surgery

Postoperative Pain

Egypt
London Vision Clinic

Completed

VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia

Refractive Errors | Myopia

United Kingdom
Genprex, Inc.

Terminated

TUSC2-nanoparticles and Erlotinib in Stage IV Lung Cancer

Lung Cancer

United States
Universidad Autonoma de Nuevo Leon

Completed

Therapeutic Effect of Botulinum Toxin A for the Treatment of Plantar Fasciitis.

Plantar Fascitis | Botulinum Toxins, Type A

Mexico
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Completed

TPI 287 in Breast Cancer Metastatic to the Brain

Breast Cancer

United States
Melinda Seering

Completed

Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block

Anesthesia, Local

United States
Ohio State University
Eisai Inc.

Completed

Effectiveness of Triple Therapy With Palonosetron for PON Prophylaxis

Postoperative Nausea and Vomiting
National Cancer Institute (NCI)

Completed

Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood

Myelodysplastic Syndrome (MDS) | Non-Hodgkin's Lymphoma (NHL) | Leukemia, Acute Myelogenous (AML) | Leukemia, Acute Lymphocytic (ALL) | Leukemia, Chronic Myelogenous (CML)

United States
Johnson & Johnson Consumer and Personal Products...

Completed

To Determine if Diphenhydramine Works for Nasal Congestion at Two Different Doses

Nasal Congestion

United States
M.D. Anderson Cancer Center

Recruiting

A Phase I/II Study of Intraperitoneal Paclitaxel in Patients With Metastatic Appendiceal Adenocarcinoma

Intraperitoneal Paclitaxel | Metastatic Appendiceal Adenocarcinoma

United States
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology

Gastric Adenocarcinoma | Carcinomatosis

United States
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome (INShore)

Childhood Idiopathic Nephrotic Syndrome

Belgium, United States, Poland, China, France, Spain, Japan, Brazil, Italy, Turkey
Yale University
Department of Anesthesiology Faculty Development Fund

Recruiting

Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study (Yale SEVEN)

Knee Arthroplasty | Total Knee Replacement

United States
Yale University

Recruiting

TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery

Pain, Acute | Opioid Use

United States
University Medical Center of Southern Nevada

Completed

Intravenous Fluids in Benign Headaches Trial (I-FiBH)

Headache

United States
Koen van Besien

Withdrawn

Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple Myeloma (AHCT)

Multiple Myeloma

United States
Shanghai Institute Of Biological Products
First Affiliated Hospital Bengbu Medical College

Completed

A Study Exploring Efficacy of Pegloticase in Subjects With Asymptomatic Hyperuricemia

Asymptomatic Hyperuricemia

China
University of Colorado, Denver

Withdrawn

Transverse Abdominus Plane Block Study (TAP)

Surgery | Colorectal Disorders

United States
University of Texas Southwestern Medical Center

Completed

A Comparison of Ropivacaine Alone Versus Combination of Dexamethasone and Clonidine for Block

Upper Extremity Surgery

United States
Bayer

Completed

A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects

Pain

United States
St. Louis University

Completed

A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective. (MAD)

Headache

United States
Complejo Hospitalario Universitario de Granada

Unknown

Blind and Ultrasound Guided Injection in Morton Neuroma

Morton Neuroma

Spain
Weill Medical College of Cornell University

Completed

Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis

Nail Diseases | Nail Psoriasis

United States
Fudan University

Active, not recruiting

Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery)

Prostate Cancer

China
University of California, Davis

Recruiting

Multimodal Analgesia Effect on Post Surgical Patient

Surgery | Obesity, Morbid | Bariatric Surgery Candidate

United States
Masonic Cancer Center, University of Minnesota
National Cancer Institute (NCI)

Recruiting

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

Pancreatic Neoplasm | Duodenal Neoplasm

United States
Dayton Children's Hospital

Recruiting

Intravenous Fluids in Pediatric Migraine

Migraine | Migraine in Children

United States
Carl Ola Landgren, MD, PhD
Bristol-Myers Squibb

Recruiting

Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma (Iber-KDd)

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Sanofi

Completed

Evaluation of SAR408701 in Japanese Patients With Advanced Malignant Solid Tumors

Neoplasm Malignant

Japan
Brian Williams
University of Pittsburgh

Completed

4-drug Nerve Block Versus Plain Local Anesthetic for Knee and Hip Arthroplasty Analgesia in Veterans

Pain

United States
Janssen Research & Development, LLC

Completed

An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD

Multiple Myeloma

United States, Spain, Canada
Joseph Hazelton

Completed

A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV)

Pain | Nausea | Vomiting

United States

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