Search clinical trials for: local anesthetic and dexmedetomidine

Total 15704 results

Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Oriel Therapeutics

Completed

Clinical Efficacy Study of Salmeterol Xinafoate/Fluticasone Propionate in Asthma

Asthma

United States
University Hospital, Tours

Completed

Evaluation of the Effectiveness of the Nebulization Bronchodilators Under High Nasal Flow Humidified (AirvoNEB)

Chronic Obstructive Pulmonary Disease

France
Assiut University

Completed

Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium Before Office Hysteroscopy

Endoscopy

Egypt
Assiut University

Completed

Oral Diclofenac Sodium Versus Oral Hyoscine Butyl Bromide During Intrauterine Device Insertion

Family Planning

Egypt
University of Missouri-Columbia
Kansas City Veteran Affairs Medical Center

Completed

Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic Dysfunction

Diastolic Dysfunction

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability of NVA237 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD) (GLOW5)

Chronic Obstructive Pulmonary Disease

Germany, India, South Africa, Croatia, Estonia, Poland, Lithuania, Guatemala, Czech Republic, France, Philippines, Korea, Republic of, Taiwan, Canada, Latvia
Novartis Pharmaceuticals

Completed

The Effect of QVA149 on Patient Reported Dyspnea in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (BLAZE)

Chronic Obstructive Pulmonary Disease

Germany, Belgium, Spain, Canada, United Kingdom
New York State Psychiatric Institute

Completed

Treatment of Depression Following Multiple Brain Tests

Major Depression | Dysthymia

United States
Kavaklıdere Umut Hospital

Unknown

Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication

Laparoscopic Nissen Fundoplication

Turkey
Eyegate Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis

Anterior Uveitis

United States
University of Nottingham

Recruiting

Asthma: Phenotyping Exacerbations 3 (APEX3)

Asthma Attack

United Kingdom
PARZIBUT Gilles

Not yet recruiting

Non-inferiority Evaluation of Trimbow in Critically Ill Patients Admitted in ICU Compared to Standard of Care (TRIMICU)

COPD Exacerbation
Chiesi Farmaceutici S.p.A.

Recruiting

A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD (TRITON)

COPD | COPD Exacerbation

United States, Bulgaria, Hungary, Poland, Argentina, Czechia, Mexico, Canada, Puerto Rico, Romania
Assistance Publique - Hôpitaux de Paris

Completed

Postoperative Vomiting in Children: Comparison Tri - Versus bi -Prophylaxis (VPOP2)

Postoperative Vomiting

France
Liaocheng People's Hospital

Recruiting

Susceptibility-Guided Sequential Therapy for Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Xijing Hospital of Digestive Diseases

Recruiting

Standard or Short-course Vonoprazan Non-bismuth Triple Therapy or High-dose Dual Therapy Versus Rabeprazole-bismuth Quadruple Therapy for Primary Helicobacter Pylori Eradication

the Eradication Rates of Helicobacter Pylori

China
AstraZeneca

Completed

A Study to Assess the Pulmonary Distribution of Budesonide, Glycopyrronium and Formoterol Fumarate

Pulmonary Disease, Chronic Obstructive

United Kingdom
Pearl Therapeutics, Inc.

Completed

24-hour Lung Function in Subjects With Moderate to Very Severe COPD After Treatment With PT003, Open-Label Spiriva® Respimat® as an Active Control, and Placebo

COPD
Ohio State University

Completed

The Response to Atropine Drops (RAD) Study

Myopia

United States
Ghada Mohammed AboelFadl

Completed

Oral Amantadine Versus Gabapentin to Attenuate the Response to Laryngoscopy and Tracheal Intubation (15/5/2017)

Effect of Laryngoscopy and Tracheal Intubation

Egypt
Mahidol University
Siriraj Hospital

Unknown

Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women

Infertility

Thailand
Jie Chen

Active, not recruiting

Effect of Glycopyrrolate on Nausea and Vomiting After ERCP Operation

Nausea and Vomiting

China
Cairo University

Completed

Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD.

IUD Insertion Pain

Egypt
Universitaire Ziekenhuizen KU Leuven

Completed

Effect of the Motilin Receptor Agonist, Erythromycin, on Hunger and Food Intake; Study of Role of Cholinergic Pathways

Healthy
Jinling Hospital, China

Recruiting

Clinical Study of Bowel Preparation Before Colonoscopy

Bowel Preparation

China
Taizhou Hospital
First Affiliated Hospital of Zhejiang University; Taizhou First People's Hospital and other collaborators

Unknown

A Multi-center Study for Eradication of Refractory Helicobacter Pylori

Gastritis

China
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction

Smoking | Nicotine Dependence | Smoking Behaviors

United States
King Abdulaziz University

Completed

The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load

COVID-19 | Covid19 | SARS-CoV-2 | Coronavirus | Saliva | Viral Load | Polymerase Chain Reaction | Mouthwashes

Saudi Arabia
Brno University Hospital
KDCHOT FN Brno

Completed

Depth of Neuromuscular Blockade and the Perioperative Conditions in Laparoscopic Surgery in Pediatric Population (PedLapBlock)

Neuromuscular Blockade

Czechia
Ziekenhuis Oost-Limburg
Merck Sharp & Dohme LLC

Completed

CURES: The Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity (CURES)

Obesity | Surgical Conditions | Respiratory Function | Laparoscopic Gastric Bypass Surgery | Cerebral Tissue Oxygenation

Belgium
University Hospital, Angers

Completed

Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

Healthy Volunteers

France
University Clinical Centre of Kosova
University of Ljubljana, Faculty of Medicine

Unknown

FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis

Type 2 Diabetes Mellitus | Periodontitis

Kosovo
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Korea, Republic of, Argentina, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Canada, India, Bulgaria, Poland
Dar El Oyoun Hospital

Unknown

Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification

Cataract | Adverse Drug Event | Mydriasis

Egypt
Merck Sharp & Dohme LLC

Completed

Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)

Dementia
Pearl Therapeutics, Inc.

Completed

Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD

Chronic Obstructive Pulmonary Disease

United States, Germany, United Kingdom, China, Taiwan, Korea, Republic of, Japan, Czechia, Hungary, Poland, Russian Federation
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)

Neuromuscular Blockade

United States, Austria, Belgium, Denmark, Germany
St. Stephens Clinical Research

Completed

RIFT: Effect of Rifampicin on Plasma PK of FTC, TAF and Intracellular TFV-DP & FTC-TP (RIFT)

HIV

United Kingdom
Mundipharma Research Limited

Terminated

A Study to Compare Fluticasone /Formoterol Breath Actuated Inhaler (BAI) and Ultibro in Subjects With Fixed Airflow Obstruction and Elevated Eosinophils

ACOS (Fixed Airflow Obstruction and Elevated Eosinophils)

Slovakia
Vanderbilt University

Completed

Treatment of Orthostatic Hypotension in Autonomic Failure

Orthostatic Hypotension | Autonomic Failure

United States
Chen Ying

Enrolling by invitation

Efficacy of Anisodamine Hydrobromide Combined With Low-molecular-weight Heparin in the Treatment of Patients With Sepsis

Sepsis

China
Alexandria University
University of Alexandria

Completed

Lactoferrin in Helicobacter Pylori Eradication Either With Standard Triple Therapy or Sequential Therapy

Helicobacter Pylori Infection

Egypt
Emergency NGO Onlus

Withdrawn

Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola) (EASE)

Ebola Virus Disease
Tesaro, Inc.

Completed

An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects

Chemotherapy-induced Nausea and Vomiting

United States
Pfizer

Terminated

Assessment Of The Effects Of Single Doses Of An Investigational Drug, Given Alone Or With Donepezil, On Scopolamine-Induced Changes In Memory And Learning In Healthy Adults

Healthy

United States
AnHeart Therapeutics Inc.

Completed

A Study of AB-106 in Chinese Healthy Adult Men Evaluated the Effects of Itraconazole and Rifampicin on AB-106 PK

Solid Tumor

China
Universitas Padjadjaran
Radboud University Medical Center; United States Agency for International Development...

Completed

High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding Study (ReDEFINe)

Tuberculosis, Meningeal

Indonesia
Chiesi Farmaceutici S.p.A.

Withdrawn

TRIMBOW® and RELVAR® on Lung Stiffness Reduction Assessed Through Forced Oscillation Technique in Patients With COPD

COPD
Peking University First Hospital
Peking University Cancer Hospital & Institute

Terminated

Dexamethasone, Flurbiprofen Axetil and Delirium After Lung Cancer Surgery

Delirium | Carcinoma, Non-Small-Cell Lung | Surgery--Complications | Dexamethasone | Flubiprofen Axetil

China

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