Search clinical trials for: metformin, topiramate

Total 2455 results

Garvan Institute of Medical Research
National Health and Medical Research Council, Australia

Recruiting

Preventing Cognitive Decline With Metformin (MetMemory)

Cognitive Decline

Australia
National Cancer Institute (NCI)

Terminated

Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

Renal Cell Carcinoma | Renal Cell Cancer | Hereditary Leiomyomatosis

United States
Cynthia Calkin
Stanley Medical Research Institute

Completed

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder (TRIO-BD)

Bipolar Disorder

United States, Canada
University of Virginia

Completed

Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome (EJB044)

Metabolic Syndrome | Insulin Sensitivity

United States
Lars Christian Gormsen

Completed

Effects of Metformin on Hepatic FFA Metabolism

Type 2 Diabetes | Dyslipidemia
Virginia Commonwealth University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacogenetics of Metformin Action in PCOS

Polycystic Ovary Syndrome

United States
Novo Nordisk A/S

Completed

Comparison of the Blood Sugar Lowering Effect Between Repaglinide Plus Metformin and Repaglinide Alone in Type 2 Diabetics Not Previously Treated With Oral Sugar-lowering Drugs

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Efficacy and Safety of Repaglinide and Metformin Combination Therapy in Type 2 Diabetes Failing on Oral Anti-diabetic Drugs

Diabetes Mellitus, Type 2 | Diabetes

China
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus

Esophageal Cancer | Barrett Esophagus

United States, Puerto Rico, Canada
Government Dental College and Research Institute...

Unknown

Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis

Intrabony Defects in Chronic Periodontitis

India
Odense University Hospital

Completed

The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Denmark
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Clinical Trial of Topiramate for Cocaine Addiction

Cocaine Dependence

United States
Zagazig University

Completed

Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Egypt
Solvay Pharmaceuticals

Completed

A Controlled-Study on the Effect of a Combination of Fenofibrate and Metformin on Weight Loss and Weight Loss-Maintenance, in Obese Patients.

Obesity

Finland
Boehringer Ingelheim
Eli Lilly and Company

Completed

Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female

Healthy

Germany
Chongqing Medical University

Completed

Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes

Diabetes

China
VIVUS LLC
Synteract, Inc.; Sentrx

Completed

A VI-0521 Study to Evaluate the Long-term Safety and Efficacy in Type 2 Diabetic Adults

Diabetes

United States
VIVUS LLC
Covance; Sentrx

Completed

A Study to Evaluate the Pharmacokinetics of VI-0521 in Subjects With Hepatic Impairment

Hepatic Impairment

United States
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes

Type 2 Diabetes

China
Services Hospital, Lahore

Completed

Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes

Diabetes, Type 2

Pakistan
Boehringer Ingelheim

Completed

Bioavailability of a Fixed Dose Combination Tablet With Empagliflozin (BI 10773) and Metformin Compared With the Monocomponents and Effect of Food on Bioavailability

Diabetes Mellitus, Type 2

Germany
UCB Korea Co., Ltd.

Completed

Levetiracetam Versus Topiramate as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset Seizures

Epilepsy

Korea, Republic of
Sun Yat-sen University

Not yet recruiting

The Effect of Metformin in Patients With Newly Diagnosed mHSPC

Metastatic Prostate Cancer

China
University of Florida
ALS Association

Active, not recruiting

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Frontotemporal Dementia | C9orf72 Amyotrophic Lateral Sclerosis (ALS)

United States
University of Pennsylvania
Pennsylvania Department of Health

Completed

Effects of Metformin During Nicotine Withdrawal (MEP)

Smoking | HIV-1-infection

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage I-III Pancreatic Cancer

United States
Tianjin Medical University Cancer Institute and...
Innovent Biologics (Suzhou) Co. Ltd.

Unknown

Sintilimab Combined With Metformin in First-Line Chemotherapy Refractory Advanced NSCLC Patients (SMART)

Non Small Cell Lung Cancer

China
Peking University

Unknown

Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) (ECMTPneo)

Esophageal Squamous Cell Carcinoma

China
University of Exeter
University of Bristol; University of Dundee

Withdrawn

Autoimmune Diabetes Accelerator Prevention Trial (adAPT)

Prediabetic State

United Kingdom
Poznan University of Medical Sciences
University of California, San Diego

Unknown

Androgen Responses to hCG and Ovarian Morphology in PCOS

PCOS

Poland
Novo Nordisk A/S

Completed

Comparison of Repaglinide and Metformin Administered Alone or in Combination in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Comparison of Metformin, Repaglinide or the Combination of Both in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Spain
HaEmek Medical Center, Israel

Completed

A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

Gestational Diabetes Mellitus

Israel
M.D. Anderson Cancer Center

Terminated

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Colorectal Carcinoma

United States
Eunice Kennedy Shriver National Institute of Child...
University of Pittsburgh; University of Washington; University of Texas; RTI International and other collaborators

Unknown

Glyburide and Metformin for Gestational Diabetes Mellitus (GDM) (GDM)

Gestational Diabetes Mellitus

United States
IlDong Pharmaceutical Co Ltd

Completed

A Open-label, Single-dose, 2-Sequence, 2-Period, Crossover Study to Assess Safety and Pharmacokinetics of a Nateglinide/Metformin HCl Combined Tablet Compared With a Nateglinide 120 mg Tablet and Metformin HCl 500 mg Tablet Under Fasting Conditions in Healthy Male Subjects

Healthy Volunteers

Korea, Republic of
GlaxoSmithKline

Completed

Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

Mexico
LG Life Sciences

Completed

Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Lady Hardinge Medical College

Recruiting

Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study (TOPAMAD)

Epileptic Spasms, Failed Hormonal Therapy

India
University of Jordan

Completed

Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan

Diabetes Mellitus, Type 2

Jordan
Shengjing Hospital

Completed

CANA/Met in Non-diabetic Women With PCOS

Polycystic Ovary Syndrome

China
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Activity and Metformin Intervention in Obese Adolescents (REACH)

Obesity | Type 2 Diabetes

Canada
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

Breast Cancer

United States
University Health Network, Toronto

Active, not recruiting

The Metformin Active Surveillance Trial (MAST) Study (MAST)

Prostate Cancer

Canada
Ain Shams University

Completed

Effect of Metformin in Children With Type 1 Diabetes

Effect of Change in T1DM Glycemic Control

Egypt
Hospital Civil de Guadalajara

Unknown

Metformin and Systemic Inflammation in HIV (Metfo)

PreDiabetes | HIV-1-infection

Mexico
University of Dundee

Completed

MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease (MET-REMODEL)

Coronary Artery Disease | Insulin Resistance | PreDiabetes | Left Ventricular Hypertrophy

United Kingdom
Postgraduate Institute of Medical Education and...
Council of Scientific and Industrial Research, India

Withdrawn

Comparison of Cardiovascular Outcomes of Pioglitazone and Metformin in Type 2 Diabetes Patients

Type 2 Diabetes

India
Sanofi

Completed

Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus (T2DM) Patients

Type 2 Diabetes Mellitus

Germany
University of Leipzig

Completed

Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease (KFO)

Obesity | Impaired Glucose Tolerance | Stable Coronary Artery Disease

Germany

Search clinical trials for: metformin, topiramate

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