Search clinical trials for: miRNA

Total 531 results

Seqirus

Active, not recruiting

Safety, Reactogenicity, and Immunogenicity Study of a Self-Amplifying mRNA Influenza Vaccine in Healthy Adults

Influenza, Human

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) After Receipt of EUA Vaccines

COVID-19

United States
Boninger, Michael, MD
National Institute of Neurological Disorders and Stroke (NINDS); Ripple Therapeutics...

Recruiting

Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation (MIRA)

Amputation | Amputation; Traumatic, Hand

United States
National Institute of Allergy and Infectious Diseases...
PPD

Completed

COVID-19 Protection After Transplant Pilot Study (CPAT)

Kidney Transplant Recipients

United States
Nova Scotia Health Authority
Obafemi Awolowo University

Not yet recruiting

Molecular Subtyping of Triple-negative Breast Cancer and African Ancestry-related Immunogenicity

Triple Negative Breast Cancer
Tang-Du Hospital
Air Force Military Medical University, China

Not yet recruiting

Exosome-based Nanoplatform for Ldlr mRNA Delivery in FH (ENDFH)

Familial Hypercholesterolemia

China
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Immunogenecity and Safety of VaccinemRNA-1273 in Elderly Volunteers (Over 65 y) Compared to Younger Ones (18-45y) (CoviCompareM)

Prevention of COVID19
ModernaTX, Inc.

Active, not recruiting

A Study of the Effectiveness of Moderna COVID-19 Vaccine

COVID-19 | SARS-CoV-2

United States
Maria Joyera Rodríguez

Withdrawn

Study About the Response to the Administration of a Third Dose of mRNA-1273 Vaccine (COVID-19 Vaccine Moderna) in Renal Transplants With Immunological Failure Initial to Vaccination (VAX-TRES)

Covid19
Real Imaging Ltd.

Unknown

Evaluation of a 3D Functional Metabolic Imaging and Risk Assessment System in Classifying Women for Likelihood of Breast Cancer

Breast Cancer

Italy
Second Affiliated Hospital of Guangzhou Medical...

Not yet recruiting

Anti-cancer Neoantigen mRNA Vaccine to Treat Solid Tumors

Solid Tumor, Adult
ModernaTX, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.

Cytomegalovirus Infection

United States
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age

Respiratory Syncytial Virus

United States, Spain, Taiwan, Korea, Republic of, Singapore, Canada, Belgium, Finland, Japan, United Kingdom, Chile, New Zealand, South Africa, Australia, Puerto Rico, Argentina, Costa Rica, Poland, Bangladesh, Colombia, Germany, ... and more
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age

Cytomegalovirus Infection

United States, Australia, Canada, France, Belgium, Germany, Israel, Italy, United Kingdom, Spain, Estonia, Finland, Japan
ModernaTX, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); Biomedical Advanced...

Completed

A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19

SARS-CoV-2

United States
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in Children 2 to <18 Years of Age at High Risk of Respiratory Syncytial Virus

Respiratory Syncytial Virus

United States, Panama
Trakya University

Unknown

Gene Expression and DNA Variation Analysis of Sacs to Identify the Pathophysiology of Indirect Inguinal Hernia

Genetic Predisposition to Disease | Indirect Inguinal Hernia

Turkey
ModernaTX, Inc.

Completed

Safety, Reactogenicity, and Immunogenicity of mRNA-1653 in Healthy Adults

Human Metapneumovirus and Human Parainfluenza Infection

United States
University of Florida

Withdrawn

Human Telomerase Reverse Transcriptase Messenger RNA (hTERT mRNA) Transfected Dendritic Cell Vaccines

Metastatic Prostate Cancer
Karolinska University Hospital
Karolinska Institutet

Active, not recruiting

COVID-19 Vaccination of Immunodeficient Persons (COVAXID) (COVAXID)

Covid19

Sweden
University Hospital, Montpellier

Completed

Small Circulating RNA as Molecular Markers of Lung Disease in Cystic Fibrosis (MIRDIAMUCO)

Cystic Fibrosis

France
Mansoura University

Completed

The Potential Role Of MicroRNA-155 And Telomerase Reverse Transcriptase In Diagnosis Of Non-Muscle Invasive Bladder Cancer And Their Pathological Correlation

Bladder Cancer | Bladder Disease | Bladder Neoplasm | Micro-RNA

Egypt
National Institute of Allergy and Infectious Diseases...
Moderna TX, Inc

Active, not recruiting

Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy Adults

Nipah Virus Infection

United States
National Institute of Allergy and Infectious Diseases...
ModernaTX, Inc.

Completed

Safety and Immunogenicity Study of 2019-nCoV Vaccine (mRNA-1273) for Prophylaxis of SARS-CoV-2 Infection (COVID-19)

COVID-19 | COVID-19 Immunisation

United States
ModernaTX, Inc.

Enrolling by invitation

A Long-Term Extension Study to Evaluate the Immunogenicity and Safety of Cytomegalovirus (CMV) mRNA-1647 Vaccine

Cytomegalovirus Infection

United States
H. Lee Moffitt Cancer Center and Research Institute
ModernaTX, Inc.

Completed

COVID-19 Immunogenicity of a Third Dose of mRNA-1273 Vaccine Among Cancer Patients

Covid19 | SARS-CoV2 Infection

United States
Radboud University Medical Center
Rotterdam Eye Hospital

Terminated

Messenger Ribonucleic Acid (mRNA) Transfected Dendritic Cell Vaccination in High Risk Uveal Melanoma Patients

Uveal Melanoma

Netherlands
Universiteit Antwerpen

Completed

Immunogenicity After COVID-19 Vaccines in Adapted Schedules (IMCOVAS)

COVID-19 | Coronavirus Disease 2019

Belgium
University of Texas Southwestern Medical Center

Withdrawn

Adenomyosis: Genomic Mechanisms and Biological Response

Adenomyosis | Abnormal Uterine Bleeding
ModernaTX, Inc.

Recruiting

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus in Pregnant Women and in Infants Born to Vaccinated Mothers

Respiratory Syncytial Virus

Canada, United Kingdom, Japan, United States, Chile, Denmark, Panama, South Africa
Sinocelltech Ltd.

Not yet recruiting

A Study to Evaluate the Immunogenicity and Safety of a Recombinant Protein COVID-19 Vaccine as a Booster Dose in Population Aged 12-17 Years

COVID-19 | SARS-CoV-2 Infection
ModernaTX, Inc.

Active, not recruiting

A Study to Investigate The Safety, Tolerability, And Immune Response of a Range of Doses of mRNA-1769 Compared With Placebo in Healthy Participants From ≥18 Years of Age to <50 Years of Age

Smallpox | Mpox

United Kingdom
ModernaTX, Inc.

Completed

Dose-Finding Trial to Evaluate the Safety and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647 in Healthy Adults

Cytomegalovirus Infection

United States
ModernaTX, Inc.

Completed

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647

Cytomegalovirus Infection

United States
ModernaTX, Inc.

Active, not recruiting

Moderna Vaccine mRNA-1345 Observational Respiratory Syncytial Virus (RSV) Study

Respiratory Syncytial Virus

United States
Mayo Clinic

Terminated

COVID-19 Vaccination in Rheumatic Disease Patients

Osteoarthritis | Systemic Lupus Erythematosus | Psoriatic Arthritis | Sjogren's Syndrome | Gout | Ankylosing Spondylitis | Inflammatory Myositis | Arthritis of Multiple Sites Associated With Inflammatory Bowel Disease (Diagnosis)

United States
ModernaTX, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-1944 in Healthy Adults

Prevention of Chikungunya Virus Infection

United States
Real Imaging Ltd.

Unknown

Evaluation of Real Imaging's 3D Functional Metabolic Imaging and Risk Assessment (MIRA) System

Breast Cancer

Israel
Chulalongkorn University
BioNet-Asia; Chula Clinical Research Center (Chula CRC), Faculty of Medicine... and other collaborators

Recruiting

Safety and Immunogenicity of ChulaCov19 BNA159 mRNA Vaccine

Safety of 25 ug of ChulaCov19-BNA159 mRNA Vaccine | Tolerability of 25 ug of ChulaCov19-BNA159 mRNA Vaccine | Immune Response of 25 ug of ChulaCov19-BNA159 mRNA Vaccine | Safety of 50 ug of ChulaCov19-BNA159 mRNA Vaccine | Tolerability of 50 ug of ChulaCov19-BNA159 mRNA Vaccine | Immune Response... and other conditions

Thailand
Changhai Hospital
Stemirna Therapeutics

Unknown

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Digestive System Neoplasms

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Colorectal Adenocarcinoma | Advanced Esophageal Squamous Carcinoma

China
Duke University
Washington University School of Medicine; University of Pittsburgh; Centers for... and other collaborators

Completed

Comparative Immunogenicity of Concomitant vs Sequential mRNA COVID-19 and Influenza Vaccinations

COVID-19 | Influenza

United States
International AIDS Vaccine Initiative
Emory University; Fred Hutchinson Cancer Center; George Washington University; ModernaTX... and other collaborators

Active, not recruiting

A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core)

Hiv

United States
West China Hospital

Recruiting

Application of mRNA Immunotherapy Technology in Hepatitis B Virus-related Refractory Hepatocellular Carcinoma

Hepatocellular Carcinoma | Liver Cancer

China
West China Hospital

Recruiting

Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors

Malignant Tumors

China
Swiss Paraplegic Research, Nottwil

Recruiting

Novel mRNA-based Urine Test for Bladder Cancer in Spinal Cord Injury Individuals

Bladder Cancer | Spinal Cord Injury

Switzerland
ModernaTX, Inc.
Biomedical Advanced Research and Development Authority

Completed

Safety, Tolerability, and Immunogenicity of mRNA-1325 in Healthy Adult Subjects

Zika Virus

United States
ModernaTX, Inc.
Biomedical Advanced Research and Development Authority

Completed

Safety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Seronegative Adults

Zika Virus

United States, Puerto Rico
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1647 Cytomegalovirus Vaccine in Healthy Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age

Cytomegalovirus

United Kingdom, United States, Canada
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1608, a Herpes Simplex Virus -2 (HSV-2) Therapeutic Candidate Vaccine, in Healthy Adults 18 to 55 Years of Age With Recurrent HSV-2 Genital Herpes

Genital Herpes

United States
ModernaTX, Inc.

Active, not recruiting

A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 12- to 30-Year-Old Healthy Adolescents and Adults

Epstein-Barr Virus Infection

United States

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