Search clinical trials for: one proton pump inhibitor(PPI)

Total 15356 results

University of Iowa

Withdrawn

Dexilant Treatment in Gastrointestinal Reflux Disease (GERD Related Non Cardiac Chest Pain (Dexilant)

Chest Pain | Gastrointestinal Reflux Disease

United States
Emory University

Unknown

A Randomized, Double-Blind, Placebo-Controlled Study of Gastroesophageal Reflux Disease Therapy.

Asthma

United States
AstraZeneca

Completed

NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis

Gastroesophageal Reflux Disease | Erosive Esophagitis | Reflux Esophagitis

United States
Casa Sollievo della Sofferenza IRCCS

Completed

High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding

Upper Gastrointestinal Bleeding | Peptic Ulcers

Italy
UMC Utrecht
Takeda

Unknown

On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication

Peptic Ulcer | GERD | GORD | Reflux | Chronic Use of Acid Suppressive Medication
Sun Yat-sen University

Unknown

Study on the Adverse Drug Reactions (ADRs) of Apatinib and Their Biomarker Correlations

Stage IV Cancer

China
Beijing Friendship Hospital

Unknown

A Study of Apatinib Combined With S1 in Patients With Advanced Gastric Cancer

Gastric Cancer

China
St. Petersburg State Pavlov Medical University

Recruiting

Evaluating of Role of Myeloperoxidase in Prediction of Outcomes of Cardiac Surgery Procedures. (MPO-CSP)

Ischemic Heart Disease | Valve Heart Disease | Cardiac Procedure Complication | Defect Septal

Russian Federation
Jiangsu vcare pharmaceutical technology co., LTD

Recruiting

Assessment of the Effect of Omeprazole on Vicagrel in Healthy Subjects

Healthy Subjects

China
UCB Biopharma SRL

Completed

A Study to Test Bioavailability of of 2 New Formulations of UCB0599 in Healthy Participants in Part A and to Test Safety, Tolerability, and Pharamacokinetic (PK) of UCB0599 in Healthy Japanese and Chinese Participants in Part B

Healthy Study Participants

United States
Jiangsu Carephar Pharmaceutical Co., Ltd.

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008

Erosive Esophagitis

United States
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Food and Acid Reducing Agents on the Absorption of Capivasertib in Healthy Participants

Solid and Hematological Malignancies

Germany
GlaxoSmithKline

Completed

GSK1325756 Relative Bioavailability Study in Healthy Elderly Subjects

Pulmonary Disease, Chronic Obstructive

United States
Fundación Pública Andaluza para la Investigación...

Unknown

Response to Oral Lansoprazole of Inorganic Pyrophosphate Levels in Patients With Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum) (FIMPXE2016-01)

Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum)

Spain
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO) (PROMO)

HCV Infections | Gastric Acid-related Disorders

Netherlands
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University

Completed

Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF) (PPIPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
Genentech, Inc.

Completed

A Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cobimetinib in Healthy Participants

Healthy Volunteer
AstraZeneca

Completed

Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma (RELAX)

Asthma | GERD

United States, Bulgaria, Czech Republic, France, Italy, Poland, Germany, Canada, Hungary, Slovakia, Argentina, Mexico, Portugal, Switzerland
Zealand University Hospital

Terminated

The Clinical Significance of Acid Rebound in Functional Dyspepsia (CLARIFY)

Functional Dyspepsia

Denmark
Eisai Inc.

Completed

Maintenance Intermittent Therapy for Symptomatic GERD Patients

Gastroesophageal Reflux Disease

United States
University of Western Ontario, Canada

Completed

Evaluation of Methods for the Determination of Chromogranin A in Routine Blood Samples

Neuroendocrine Carcinoma (Carcinoid)

Canada
David A. Johnson, MD
AstraZeneca

Completed

Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performance

GERD

United States
Inje University

Withdrawn

Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERD (DRNERD)

Gastroesophageal Reflux Disease

Korea, Republic of
AstraZeneca

Completed

Reflux Esophagitis Phase III Study (Initial Treatment)

Reflux Esophagitis

Japan
Nantes University Hospital

Completed

Comparison of Antisecretory Effect of a Single Dose of Rabeprazole 20 mg and Omeprazole 20 mg in Obese Subjects (Oberab)

Gastroesophageal Reflux

France
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Omeprazole Magnesium 20 mg DR Capsule Under Fed Conditions

Healthy

India
Eisai Inc.

Completed

E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers

Heartburn

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

PK Study for Endostar Continuous Intravenous Infusion in NSCLC Patients With 1st-line Platinum Based Chemotherapy

Advanced or Metastatic NSCLC

China
Zhongshan Hospital Xiamen University

Unknown

Camrelizumab Combined With Apatinib in the Treatment of Patients With Advanced Gastric Cancer and Colorectal Cancer

Colorectal Cancer Recurrent

China
Third Military Medical University

Unknown

Apatinib and Chemotherapy Sequential Treatment With Cervical Cancer

Cervical Cancer

China
Baylor College of Medicine

Terminated

On-Q Pump vs Epidural for Postoperative Pain Control in Children

Postoperative Pain

United States
AstraZeneca

Terminated

Study Comparing Esomeprazole and ASA Combined Together as One Capsule Versus These Medications Taken Separately

Peptic Ulcer Disease

Canada
National Cancer Institute (NCI)

Active, not recruiting

Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma

Metastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Cutaneous Melanoma

United States
Icahn School of Medicine at Mount Sinai

Completed

High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population

Helicobacter Pylori Infection

United States
Carlos Roberto Simons-Linares

Recruiting

OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers (OPEN-IT)

Marginal Ulcer

United States
Onconic Therapeutics Inc.

Recruiting

JP-1366 20mg Versus Esomeprazole 40mg in Patients With Erosive Esophagitis

Erosive Esophagitis

Korea, Republic of
Celgene

Completed

Relative Bioavailability Study of CC-292

Healthy Volunteers

United States
Sihuan Pharmaceutical Holdings Group Ltd.

Completed

A Phase 2 Randomised Controlled Trial to Evaluate Efficacy and Safety of Anaprazole in Patients With Duodenal Ulcers.

Duodenal Ulcer，DU

China
Kaohsiung Veterans General Hospital.

Completed

On-demand PPI Therapy is Effective on Controlling Symptoms in Patients With Barrett's Esophagus.

Barrett Esophagus | Reflux | Proton Pump Inhibitor | Symptom
First Affiliated Hospital, Sun Yat-Sen University

Completed

The Primary Symptoms of GERD(Gastroesophageal Reflux Disease) in Chinese Outpatients in Gastroenterology Department

Gastroesophageal Reflux

China
Indiana University

Terminated

The Effects of Dexlansoprazole for the Treatment of Throat-Related Reflux

Laryngopharyngeal Reflux

United States
Takeda

Completed

A Study to Evaluate the Bioequivalence of Single Oral Dose of Esomeprazole Capsule and Tablet Formulation in Healthy Participants

Healthy Participants

United States
Pfizer

Completed

Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment

Heartburn

United States
Ahn-Gook Pharmaceuticals Co.,Ltd

Unknown

S-pantoprazole 10mg Phase III Clinical Study

Non Erosive Reflux Disease

Korea, Republic of
AstraZeneca
Quintiles, Inc.

Completed

To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole

Heartburn

China
Norgine

Completed

A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting Conditions

Acid Reflux | Gastro Oesophageal Reflux Disease

United Kingdom
American Institute for Voice and Ear Research

Terminated

Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux

Laryngopharyngeal Reflux

United States
Chang Gung Memorial Hospital

Completed

Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease

Gastroesophageal Reflux Disease | Heartburn

Taiwan
University of North Carolina, Chapel Hill
AstraZeneca

Completed

The Utility of Nexium in Chronic Cough and Reflux Disease

Cough | GERD

United States
Takeda

Completed

The Use of Lansoprazole to Treat Infants With Symptoms of Gastroesophageal Reflux

Gastroesophageal Reflux Disease

Poland, United States

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