Search clinical trials for: placebo oxycodone / naloxone

Total 54611 results

Kalyra Pharmaceuticals, Inc.
United States Department of Defense; PRA Health Sciences

Terminated

A Single and Multiple Ascending Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of KP-1199

Analgesia

United States
Centre for Addiction and Mental Health
University of Toronto

Completed

Abuse Liability of Controlled-Release Oxycodone Formulations

Substance-Related Disorders

Canada
Astellas Pharma Global Development, Inc.

Withdrawn

A Study to Assess the Safety and Efficacy of ASP8062 as an Add-on Therapy to Buprenorphine/Naloxone in Participants With Opioid Use Disorder

Opioid Use Disorder
University of California, San Francisco

Terminated

Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain

Temporomandibular Joint Dysfunction Syndrome | Burning Mouth Syndrome

United States
Milton S. Hershey Medical Center

Withdrawn

Buprenorphine Induction for Fentanyl Dependent Opioid Users

Opioid Dependence Fentanyl

United States
NYU Langone Health
Emergency Medicine Foundation

Completed

Buprenorphine Loading in the Emergency Department

Opioid-use Disorder

United States
University of California, Los Angeles

Completed

Buprenorphine/Naloxone Versus Clonidine for Outpatient Opiate Detoxification - 1

Heroin Dependence | Substance Withdrawal Syndrome | Morphine Dependence

United States
Maimonides Medical Center

Terminated

Buprenorphine Treatment: A Safe Alternative for Opioid Dependent Pain Patients

Opioid Use Disorder

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Assessing Abuse Potential of Parenteral Buprenorphine/Naloxone in Non-Dependent Opioid Abusers

Opioid-Related Disorders

United States
King's College London
South London and Maudsley NHS Foundation Trust

Recruiting

Psilocybin in Depression Resistant to Standard Treatments (PsiDeR)

Treatment Resistant Depression

United Kingdom
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid (OPI-15-001)

Drug Overdose

Norway
Pfizer

Completed

A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers

Chronic Pain | Analgesia | Acute Pain | Opioid-related Disorders | Narcotic Abuse

United States
CBT4CBT, LLC

Completed

CBT4CBT for Office Based Buprenorphine

Opioid-use Disorder

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine/Naloxone Stabilization and Induction Onto Injection Naltrexone

Opioid Dependence

United States
Indivior Inc.

Completed

Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444)

Opioid-Related Disorders | Drug Abuse | Opiate Dependence

Austria
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA)

Terminated

Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug Users

HIV Infections | Opioid-Related Disorders

China, Thailand
New York State Psychiatric Institute

Completed

Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse (PAIN)

Opioid Dependence

United States
National Institute of Nursing Research (NINR)

Completed

Hormone Function in Men Treated for Pain With Opioids or Placebo

Osteoarthritis | Chronic Pain

United States
Murdoch Childrens Research Institute

Recruiting

Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone (POPCORN)

Patient-Controlled Analgesia

Australia
University of Rochester
Endo Pharmaceuticals

Terminated

Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis

Multiple Sclerosis | Chronic Pain | Neuropathic Pain

United States
New York State Psychiatric Institute
Alkermes, Inc.

Terminated

Buprenorphine Stabilization and Induction Onto Vivitrol for Heroin-dependent Individuals

Heroin Dependence

United States
Unity Health Toronto
University of Toronto; Toronto Public Health; Ontario College of Art and Design...

Withdrawn

Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) (SOONER)

Opioid-Related Disorders | Opioid Use | Education | Opioid Withdrawal | Opioid Overdose | Resusitation

Canada
NanoSHIFT LLC

Completed

A Single-Dose Study of an Investigational Capsule Formulation of 2 mg/0.5 mg Buprenorphine/Naloxone

Healthy

United States
University of California, Los Angeles

Completed

Buprenorphine/Naloxone Versus Clonidine for Inpatient Opiate Detoxification - 1

Heroin Dependence | Substance Withdrawal Syndrome | Morphine Dependence

United States
Leiden University Medical Center

Not yet recruiting

Influence of Oxycodone on Individuals Taking an SSRI (OXIS)

Depressive Disorder | Anxiety Disorders | Opioid Induced Respiratory Depression
QRxPharma Inc.

Completed

Efficacy and Safety of Q8003 in the Management of Post-bunionectomy Pain

Postoperative Pain

United States
Massachusetts General Hospital

Not yet recruiting

A Prospective, Randomized Trial of the Effect of Standard of Care Reduced Dose Versus Full Dose Buprenorphine/Naloxone in the Perioperative Period on Pain Control and Post-Operative Opioid Use Disorder Symptoms

Opioid-use Disorder | Opioid Use Disorder, Mild
Pfizer
Syneos Health

Completed

A Study to Characterize the Abuse Liability of ALO-02 in Healthy, Non-Dependent, Recreational Opioid Users When ALO-02 Capsules Are Crushed and Snorted

Healthy

Canada
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone

Healthy Subjects | Pharmacokinetics | Opioid Antagonist

United States
Nassima Ait-Daoud Tiouririne

Unknown

Measures to Improve Outcomes After an Opioid Overdose

Opioid Overdose

United States
Vertex Pharmaceuticals Incorporated
Tibotec BVBA

Completed

Drug-Drug Interaction Study Between Telaprevir and Buprenorphine

Hepatitis C | Opioid-Related Disorders

United States
Emory University

Recruiting

Opioid-Free Orthopaedics

Pain | Pain, Postoperative

United States
University of California, Irvine

Recruiting

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

Hyperalgesia

United States
New York State Psychiatric Institute

Terminated

Evaluation of Doxazosin to Alter the Abuse of Oxycodone

Opioid-use Disorder

United States
University of Rochester

Terminated

Open-Label Trial Comparing Oxycodone Medications (OUTCOMES)

Chronic Pain

United States
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Investigate the Pharmacodynamic Effect of Single Doses of MT-8554 in Healthy Subjects

Healthy

United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

An Efficacy and Safety Study of Oral Osmotic Therapeutic System (OROS) Hydromorphone Hydrochloride (HCl) in Participants With Cancer Related Pain

Pain

China
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Maternal Buprenorphine-naloxone Treatment and the Infant

Maternal Opioid Use Disorder | Opioid Exposed Infant

United States
University of California, Davis
Yale University; University of Utah

Not yet recruiting

Feasibility of Pediatric Emergency Department-Initiated Treatment for Adolescents With Opioid Use Disorder (PEDsTREATOUD)

Opioid-use Disorder
MedicaSafe, Inc.
Friends Research Institute, Inc.

Unknown

Improving Office Based Treatment of Opioid Use Disorder With Technology

Opioid-use Disorder

United States
Massachusetts General Hospital

Unknown

Effect of Buprenorphine/Naloxone Continuation on Pain Control and Opioid Use

Surgery | Pain, Acute | Opioid-use Disorder
National Institute on Drug Abuse (NIDA)
Organization to Achieve Solutions in Substance Abuse (OASIS)

Completed

Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1

Hepatitis C | Heroin Dependence

United States
Indivior Inc.
Taipei City Psychiatric Center, Taiwan

Completed

Multicentre Trial of Suboxone in Opiate-dependent Subjects in Taiwan

Opiate Dependence

Taiwan
Indivior Inc.

Completed

Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603)

Opioid-Related Disorders | Drug Abuse | Opiate Dependence
Bausch Health Americas, Inc.

Completed

Randomised, Placebo-controlled Safety and Pharmacokinetics Study of Novel Rifaximin Formulations in Healthy Volunteers

Healthy Volunteers

New Zealand
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Unknown

Naloxone in Treating Constipation in Patients Who Are Receiving Opioids for Chronic Pain

Unspecified Adult Solid Tumor, Protocol Specific | Constipation, Impaction, and Bowel Obstruction

United States
Friends Research Institute, Inc.
MATClinics

Recruiting

Low-dose Versus a High-dose Sublingual Buprenorphine Induction

Opioid Use Disorder

United States
Friends Research Institute, Inc.
National Institute on Drug Abuse (NIDA); Baltimore City Health Department

Enrolling by invitation

Opioid Use Disorder Treatment Linkage at Sexual Health Clinics Using Buprenorphine (OUTLAST-B)

Opioid-use Disorder

United States
University of Vermont

Unknown

Interim Buprenorphine Treatment to Bridge Waitlist Delays: Stage II Evaluation

Opioid-use Disorder

United States
GL Pharm Tech Corporation

Completed

A Randomized, Open-label, Multiple-dose, Two-sequence, Two-period Crossover Study to Investigate The Pharmacokinetics Between a GL2907 and Oxycontin CR Tab. 10mg in Healthy Male Volunteers

Healthy

Korea, Republic of

Search clinical trials for: placebo oxycodone / naloxone

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