Search clinical trials for: Protease Inhibitors

Total 64266 results

Jonathan Stine
Grifols Therapeutics LLC

Withdrawn

Preventing de Novo Portal Vein Thrombosis With Antithrombin-III in Patients With Cirrhosis (PiVoT)

Cirrhosis, Liver | Portal Vein Thrombosis

United States
Boehringer Ingelheim

Completed

Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT)

Atrial Fibrillation

Spain, United States, United Kingdom, Canada, Germany, Italy, Japan, Belgium, Netherlands, France, Russian Federation
Kyowa Kirin Co., Ltd.

Completed

An Open-label Study of KW-3357 (3357-004)

Disseminated Intravascular Coagulation (DIC)

Japan
Kyunghee University Medical Center

Unknown

Pleotropic Effect of New Oral Anticoagulants

Atrial Fibrillation

Korea, Republic of
Boehringer Ingelheim

Completed

Pharmacokinetics, Safety and Pharmacodynamics After Multiple Oral Doses of Dabigatran Etexilate Capsule in Healthy Japanese and Caucasian Male Subjects

Healthy
HLB Pharmaceutical Co., Ltd.

Unknown

Phase 1 Single Dose Escalation Study of CTB-001

Healthy

Korea, Republic of
The Medicines Company

Completed

Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)

Thrombosis | Heparin-Induced Thrombocytopenia

United States
AstraZeneca
Eli Lilly and Company

Completed

A Drug-drug Interaction Study of Lanabecestat (LY3314814) in Healthy Participants

Healthy

United States
Boehringer Ingelheim

Completed

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Atrial Fibrillation

Korea, Republic of
Vanderbilt University Medical Center
Boehringer Ingelheim

Completed

Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism

Atrial Fibrillation | Atrial Flutter

United States
Nova Scotia Health Authority

Withdrawn

Validation of a Novel Dabigatran Based Peri-Operative Bridging Anticoagulation Protocol for Patients on Chronic Warfarin Therapy

Venous Thromboses
Children's Hospital Los Angeles

Withdrawn

Pharmacokinetic Study of Recombinant AT III in Neonates Undergoing ECMO

Neonates on ECMO

United States
Austin Health
Northern Health and Social Care Trust; Western Hospital, Australia

Unknown

Angiotensin in Septic Kidney Injury Trial (ASK-IT)

Sepsis | Septic Shock | Acute Renal Failure

Australia
National Institutes of Health Clinical Center (CC)

Completed

Heparin Versus Lepirudin Flushes in Preventing Blockage of Venous Access Devices

Thrombosis

United States
Mayo Clinic

Completed

The Effects of HIV Protease Inhibitors in Severe Sepsis

Sepsis

United States
Heidelberg Pharma AG

Completed

Gemcitabine With or Without WX-671 in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery

Pancreatic Cancer

Spain, Germany, Hungary, Italy, Russian Federation, Ukraine
Ain Shams University

Completed

Human Epididymis Protein 4 in Endometrial Carcinoma

Endometrial Cancer

Egypt
Bristol-Myers Squibb

Completed

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

HIV-Associated Lipodystrophy Syndrome

Spain, Italy, United States, Canada, France, Mexico, United Kingdom, Poland, Germany
Grifols Therapeutics LLC

Completed

Deposition of Inhaled Prolastin in Cystic Fibrosis Patients (CF2)

Cystic Fibrosis
Northwestern University

Suspended

Study To antagOnize Plasminogen Activator Inhibitor-1 in Severe COVID-19

Covid19

United States
Northwell Health
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Terminated

Nelfinavir in Systemic Lupus Erythematosus (NISLE)

Systemic Lupus Erythematosus

United States
Universität des Saarlandes

Completed

Alpha-1-Antitrypsin-Deficiency in COVID-19 (CORSAAR-AAT)

Covid19

Germany
University of Rostock

Unknown

AKI Cardiosurgery Diagnostic Study (AKI-CDS) (AKI-CDS)

Acute Kidney Injury | Renal Replacement Therapy

Germany
Jilin University

Recruiting

Anti-CoagulaTion on Left Ventricular Thrombus After ST Segment Elevation Myocardial Infarction (ACTonLVT)

ST-segment Elevation Myocardial Infarction (STEMI) | Left Ventricular Thrombus

China
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Venous Thromboembolism...

Recruiting

COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation (COBRRA-AF)

Atrial Fibrillation

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Venous Thromboembolism...

Completed

Comparison of Bleeding Risk Between Rivaroxaban and Apixaban (COBRRA Pilot)

Venous Thromboembolism

Canada
Bayer
Janssen Research & Development, LLC

Completed

A Non-interventional Study on Xarelto for Treatment of Venous Thromboembolism (VTE) and Prevention of Recurrent VTE in Patients With Active Cancer (COSIMO)

Venous Thrombosis and Pulmonary Embolism

Italy, Germany, United Kingdom, France, Belgium, Canada, Netherlands, Spain, Denmark, Australia
Scott C. Woller, MD
Bristol-Myers Squibb; University of Utah

Completed

Apixaban for Secondary Prevention of Thromboembolism Among Patients With AntiphosPholipid Syndrome (ASTRO-APS)

Thrombosis | Antiphospholipid Syndrome

United States
Bayer
Janssen Scientific Affairs, LLC

Completed

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study (XASSURE)

Stroke

China
Perosphere Pharmaceuticals Inc, a wholly owned...
Quintiles, Inc.

Completed

Study of PER977 Administered to Subjects With Steady State Edoxaban Dosing and Re-anticoagulation With Edoxaban

Anticoagulation Reversal

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Clinical Management of Argatroban in Patients With Heparin Induced Thrombocytopenia Type II

Heparin-induced Thrombocytopenia Type II

France
Merck Sharp & Dohme LLC

Completed

A Study to Investigate Biomarkers After Single Doses of Anticoagulants in Healthy Young Male and Healthy Elderly Participants (MK-0000-216 AM1)

Thrombosis
Pfizer
Bristol-Myers Squibb

Completed

A Phase 2 Study To Evaluate The Safety Of Apixaban In Atrial Fibrillation

Atrial Fibrillation

Japan
Chinese PLA General Hospital
Changhai Hospital; Southwest Hospital, China; General Hospital of Beijing PLA...

Unknown

Ulinastatin in Inhalation Lung Injury

Inhalation Injury

China
ViiV Healthcare
GlaxoSmithKline

Completed

Fosamprenavir Versus Other Protease Inhibitors

Infection, Human Immunodeficiency Virus I

United States, Puerto Rico
Abbott Medical Devices

Terminated

Safety Study on Stopping Anticoagulation Medication in Patients With a History of Atrial Fibrillation (TACTIC AF)

Atrial Fibrillation

United States
University Children's Hospital, Zurich

Recruiting

Short and Long-arm Fiberglass Cast Immobilization for Distal Salter Harris I and II Forearm Fractures in Children

Fracture Forearm

Switzerland
Intermountain Health Care, Inc.
Boehringer Ingelheim

Completed

Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation (CAF)

Dementia | Cognition Disorders | Cerebral Ischemic Events

United States
Medical University of South Carolina
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma

Interstitial Lung Disease | Scleroderma

United States
Research Institute for Complex Problems of Cardiovascular...

Unknown

Dabigatran in Patients With Atrial Fibrillation and Mitral Biological Prostheses

Atrial Fibrillation | Mitral Valve Stenosis and Insufficiency

Russian Federation
Meshalkin Research Institute of Pathology of Circulation

Unknown

Pradaxa or Warfarin for Prevention of Recurrent VTE in Patients With Angiographically Confirmed Acute Massive Pulmonary Embolism undergoIng Endovascular Mechanical Fragmentation and Thrombolytic Therapy (Re-Spire)

Angiographically Confirmed Acute Massive Pulmonary Embolism Treated With Endovascular Mechanical Fragmentation and Thrombolytic Therapy

Russian Federation
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Venous Thromboembolism... and other collaborators

Not yet recruiting

VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy (PREVENT-GU)

Venous Thromboembolism | Urologic Cancer
Brigham and Women's Hospital

Recruiting

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk (EMPOWER)

Stable Coronary Disease

United States
Mitsubishi Tanabe Pharma GmbH

Completed

Safety of Argatroban Infusion in Conduction Disturbances (SAICoDis)

Stable Coronary Artery Disease (CAD) | Unstable Angina (Troponin Negative)

Germany
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Deep Vein Thrombosis | Pulmonary Embolism | Metastatic Malignant Solid Neoplasm | Cerebral Vein Thrombosis | Splanchnic Vein Thrombosis

United States
Bayer

Completed

A Study to Learn Whether There Are Differences in the Kidney's Ability to Work Properly in Korean Patients With Non-valvular Atrial Fibrillation (Irregular and Often Rapid Heartbeat Not Caused by a Heart Valve Problem) Treated With Rivaroxaban as Compared to Those Treated With Warfarin (RENOVATOR)

Non-valvular Atrial Fibrillation (NVAF)

Korea, Republic of
Second Affiliated Hospital, School of Medicine,...

Completed

Efficacy Argatroban in Ischemic Stroke With Early Deterioration (EASE) (EASE)

Acute Progressive Ischemic Stroke

China
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 2 of 4)

Healthy Volunteers
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 4 of 4)

Healthy Volunteers
Fujita Health University

Completed

Rivaroxaban Estimation With Warfarin in Atrial Fibrillation Patients With Coronary Stent Implantation Study (REWRAPS) (REWRAPS)

Coronary Artery Disease | Stroke | Atrial Fibrillation | All Cause Mortality | Fetal Blood Loss | Major Bleeding

Japan

Search clinical trials for: Protease Inhibitors

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