Search clinical trials for: Protease Inhibitors

Total 64286 results

Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
University of Calgary
Merck Sharp & Dohme LLC

Completed

Triple-Therapy in Patients With HCV Genotype 3 Who Previously Failed Treatment (LeeG3)

Hepatitis C

Canada
Peking University Third Hospital

Recruiting

Effect of Oral D-mannose Tablets on Pharmacokinetics of Dabigatranate in Healthy Adults

Health

China
University Hospital, Grenoble
University Hospital, Rouen; University Hospital, Paris

Recruiting

Bradykinin-degradating Enzymes Activities in Angiotensin-Converting Enzyme Inhibitors-associated Angioedema (KIN-ACE)

Angio-Oedema Caused by Angiotensin-Converting-Enzyme Inhibitor

France
Alexander Flannery

Completed

Renin and Renal Biomarker Response to Angiotensin II

Septic Shock | Acute Kidney Injury

United States
Corcept Therapeutics

Completed

Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants

Neoplasms | Cushing Syndrome

United States
University of Oulu
Tampere University Hospital

Completed

PRCT-study of Different Non-operative Treatment Protocols of ER-stress Negative Weber-B Unimalleolar Ankle Fractures.

Lateral Malleolus Fractures

Finland
Daniel Zimpfer, MD

Terminated

Dabigatran as an Alternative Anticoagulant in Patients With Left Ventricular Assist Device (LVAD)

Thrombosis | Bleeding

Austria
Massachusetts General Hospital

Completed

Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV

HIV-infection

United States
Boehringer Ingelheim

Completed

Single and Multiple Oral Doses of Dabigatran Etexilate in Healthy Chinese Subjects

Healthy
Speedel Pharma Ltd.
Quintiles, Inc.

Completed

A Clinical Study to Assess the Safety of PEG-Hirudin (SPP200) Compared to Heparin in Patients Who Are on Haemodialysis

Chronic Kidney Failure | Vascular Graft Occlusion

United States
The Medicines Company

Completed

Comparison of Angiomax Versus Heparin in Acute Coronary Syndromes (ACS)

Myocardial Infarction | Acute Disease | Unstable Angina

United States
Korea University Anam Hospital

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Rivaroxaban 15mg and 20mg in Patients With Non-valvular Atrial Fibrillation (REVISE-AF)

Atrial Fibrillation | Anticoagulant Adverse Reaction

Korea, Republic of
Region Stockholm
Uppsala University

Recruiting

Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation (SACK)

Stroke | Chronic Kidney Diseases | Death | Atrial Fibrillation | Intracerebral Hemorrhage | Kidney Transplant; Complications | Thromboses, Venous | Cardiovascular Complication | Major Bleed

Sweden, Norway, Finland, Iceland
Hospital do Servidor Publico Estadual

Not yet recruiting

Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer (Ésquilo)

Colonic Cancer | Deep Venous Thrombosis

Brazil
Duke University

Recruiting

The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation

Glioblastoma | Malignant Glioma

United States
Bayer
Janssen Research & Development, LLC

Active, not recruiting

A Study to Evaluate the Safety and Effectiveness of Rivaroxaban (Xarelto) for Prevention of Stroke and Systemic Embolism in Indian Patients With Non-valvular Atrial Fibrillation (NVAF) (XARIN)

Non-valvular Atrial Fibrillation (NVAF)

India
Portola Pharmaceuticals

Completed

Phase 2 Study of the Safety, Tolerability and Pilot Efficacy of Oral Factor Xa Inhibitor Betrixaban Compared to Warfarin (EXPLORE-Xa)

Atrial Fibrillation

United States, Canada
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 1 of 4)

Healthy Volunteers

United States
Stanford University

Completed

Oral Camostat Compared With Standard Supportive Care in Mild-Moderate COVID-19 Patients (COPS-2003)

Covid19

United States
Sagent Pharmaceuticals Inc.

Completed

Camostat Efficacy vs. Placebo for Outpatient Treatment of COVID-19 (CAMELOT)

COVID-19

United States
Pirogov Russian National Research Medical University

Completed

Rivaroxaban With Diosmin in Long-term Treatment of Deep Vein Thrombosis (RIDILOTT-DVT)

Deep Vein Thrombosis | Postthrombotic Syndrome

Russian Federation
Electrophysiology Research Foundation
Axio Research Corporation

Terminated

EdoxabaN or Warfarin Therapy In Device Procedures in Patients With Non-Valvular Atrial Fibrillation (ENTICED-AF)

Atrial Fibrillation

United States
Zagazig University

Completed

Efficacy and Safety of Rivaroxaban in Acute Non-neoplastic Portal Vein Thrombosis in HCV

Portal Vein Thrombosis
Bristol-Myers Squibb
Pfizer

Completed

Phase 1 Bioavailability Study of Apixaban Solution Formulation Relative to Apixaban Tablets in Healthy Subjects

Healthy Volunteers

United States
GlaxoSmithKline

Completed

ARIXTRA® Adherence in SVT Patients.

Thrombosis, Venous
Yonsei University

Completed

Effects of Ulinastatin on Coagulation in High Risk Patients Undergoing Off Pump Coronary Artery Bypass Graft Surgery

Coronary Artery Occlusive Disease

Korea, Republic of
Karolinska Institutet
Karolinska University Hospital; Pfizer

Recruiting

imPROving Quality of LIFe In the Long COVID Patient (PROLIFIC)

COVID-19 | Post-COVID-19 Syndrome | Long COVID | Long Covid19 | Post COVID-19 Condition | Post-COVID Syndrome | Post COVID-19 Condition, Unspecified | POTS - Postural Orthostatic Tachycardia Syndrome | Postinfectious Inflammation | Postinfectious Disorder

Sweden
Abramson Cancer Center of the University of Pennsylvania

Terminated

Proton Beam Radiation With Concurrent Chemotherapy and Nelfinavir for Inoperable Stage III Non Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

United States
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Completed

Optimization of Darunavir Therapy and Dosage Recommendations

Human Immunodeficiency Virus I Infection

Belgium
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C202: A Study of Safety, Efficacy, and Tolerability of TMC114 and Low Dose Ritonavir in HIV-1 Infected Patients

HIV Infections

United States, Argentina
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors

Nasopharyngeal Cancer | Gastric Cancer | Hodgkin Lymphoma | Castleman Disease | Non-Hodgkin Lymphoma | Kaposi Sarcoma | EBV

United States
Brigham and Women's Hospital
National Institutes of Health (NIH)

Completed

A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Tibotec Pharmaceuticals, Ireland

Completed

An Open Label Trial of TMC114/RTV in HIV-1 Infected, Treatment-experienced Subjects.

HIV Infection

United States, Australia, France, United Kingdom, Germany, Spain, Belgium, Portugal, Canada, Argentina, Brazil, Austria, Hungary
Fundacion SEIMC-GESIDA
ViiV Healthcare

Completed

HCV Evolution in HIV/HCV (Genotype 1) Coinfected Patients Treated With Fosamprenavir (FOSTER-C)

HCV Coinfection | Chronic HIV Infection

Spain
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-TiDP3-C181: Study to Assess the Pharmacokinetics of Darunavir (DRV) With Different Doses of Ritonavir in Healthy Volunteers.

HIV | AIDS
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C201: A Study to Determine the Antiviral Activity of TMC114 in Patients With Multiple Protease Inhibitor (PI) Resistant Human Immunodeficiency Virus (HIV) Strains

HIV Infections
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in HIV-Positive Women

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3

HIV Infections | Sarcoma, Kaposi

United States
Agouron Pharmaceuticals

Completed

Phase I Study of Safety, Tolerability, and Pharmacokinetics of Viracept in HIV-1 Infected Children and Exposed Infants

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Viracept Expanded Access Program

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected Patients

HIV Infections

United Kingdom
China National Center for Cardiovascular Diseases

Not yet recruiting

Low-dose Versus Standard-dose Rivaroxaban in Elderly Patients With Atrial Fibrillation

Stroke | Atrial Fibrillation | Major Adverse Cardiac Events | Anticoagulant Adverse Reaction
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); Amgen

Not yet recruiting

Mechanistic Clinical Trial of PCSK9 Inhibition for AAA

Abdominal Aortic Aneurysm
Kevin H.M. Kuo, MD, MSc, FRCPC

Recruiting

THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS) (THIS)

Sickle Cell Disease | Venous Thromboembolism | Central Venous Catheter Thrombosis

Canada
University of Texas at Austin
University of Kansas

Not yet recruiting

Restart TICrH Alpha Pilot Protocol, Restarting DOACs After Traumatic Intracranial Hemorrhage

Anticoagulants; Increased
McMaster University

Recruiting

Postoperative Extended Venous Thromboprophylaxis in Inflammatory Bowel Disease (EXPAND)

Crohn Disease | Ulcerative Colitis | Venous Thromboembolism | Colorectal Disorders | Pulmonary Embolism | IBD

Canada
Brigham and Women's Hospital

Active, not recruiting

Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism (HI-PRO)

Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolism

United States
Montreal Heart Institute
Servier

Active, not recruiting

Canadian EdoxAban(Lixiana®) Registry in Patients With ATrial Fibrillation/Flutter With Confirmed ValvUlar HeaRt DiseasE (CAPTURE)

Valvular Heart Disease | Atrial Fibrillation and Flutter

Canada

Search clinical trials for: Protease Inhibitors

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