Search clinical trials for: proton pump inhibitor use

Total 11633 results

Sun Yat-sen University
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Camrelizumab(SHR-1210) Combined With Apatinib in the Treatment of Advanced Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Jiangsu vcare pharmaceutical technology co., LTD

Recruiting

Assessment of the Effect of Omeprazole on Vicagrel in Healthy Subjects

Healthy Subjects

China
UCB Biopharma SRL

Completed

A Study to Test Bioavailability of of 2 New Formulations of UCB0599 in Healthy Participants in Part A and to Test Safety, Tolerability, and Pharamacokinetic (PK) of UCB0599 in Healthy Japanese and Chinese Participants in Part B

Healthy Study Participants

United States
Jiangsu Carephar Pharmaceutical Co., Ltd.

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008

Erosive Esophagitis

United States
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Food and Acid Reducing Agents on the Absorption of Capivasertib in Healthy Participants

Solid and Hematological Malignancies

Germany
GlaxoSmithKline

Completed

GSK1325756 Relative Bioavailability Study in Healthy Elderly Subjects

Pulmonary Disease, Chronic Obstructive

United States
Fundación Pública Andaluza para la Investigación...

Unknown

Response to Oral Lansoprazole of Inorganic Pyrophosphate Levels in Patients With Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum) (FIMPXE2016-01)

Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum)

Spain
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO) (PROMO)

HCV Infections | Gastric Acid-related Disorders

Netherlands
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University

Completed

Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF) (PPIPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
Genentech, Inc.

Completed

A Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cobimetinib in Healthy Participants

Healthy Volunteer
AstraZeneca

Completed

Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma (RELAX)

Asthma | GERD

United States, Bulgaria, Czech Republic, France, Italy, Poland, Germany, Canada, Hungary, Slovakia, Argentina, Mexico, Portugal, Switzerland
Zealand University Hospital

Terminated

The Clinical Significance of Acid Rebound in Functional Dyspepsia (CLARIFY)

Functional Dyspepsia

Denmark
Eisai Inc.

Completed

Maintenance Intermittent Therapy for Symptomatic GERD Patients

Gastroesophageal Reflux Disease

United States
University of Western Ontario, Canada

Completed

Evaluation of Methods for the Determination of Chromogranin A in Routine Blood Samples

Neuroendocrine Carcinoma (Carcinoid)

Canada
David A. Johnson, MD
AstraZeneca

Completed

Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performance

GERD

United States
Inje University

Withdrawn

Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERD (DRNERD)

Gastroesophageal Reflux Disease

Korea, Republic of
AstraZeneca

Completed

Reflux Esophagitis Phase III Study (Initial Treatment)

Reflux Esophagitis

Japan
Nantes University Hospital

Completed

Comparison of Antisecretory Effect of a Single Dose of Rabeprazole 20 mg and Omeprazole 20 mg in Obese Subjects (Oberab)

Gastroesophageal Reflux

France
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Omeprazole Magnesium 20 mg DR Capsule Under Fed Conditions

Healthy

India
Eisai Inc.

Completed

E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers

Heartburn

United States
Zhongshan Hospital Xiamen University

Unknown

Camrelizumab Combined With Apatinib in the Treatment of Patients With Advanced Gastric Cancer and Colorectal Cancer

Colorectal Cancer Recurrent

China
Third Military Medical University

Unknown

Apatinib and Chemotherapy Sequential Treatment With Cervical Cancer

Cervical Cancer

China
Icahn School of Medicine at Mount Sinai

Completed

High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population

Helicobacter Pylori Infection

United States
Nationwide Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

GERD Infant Feeding Therapeutics Trial (GIFT Trial) (GIFT)

GERD in Infants

United States
Chinese University of Hong Kong
Nanfang Hospital, Southern Medical University

Recruiting

PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers

Proton Pump Inhibitors | Upper GI Bleeding

China
The University of Texas Health Science Center at...

Recruiting

Dermaprazole Cream for Radiation Dermatitis in Head and Neck Cancer

Cancer of the Head and Neck

United States
Shinshu University

Recruiting

Efficacy of Proton Pump Inhibitors in Gastrointestinal Erosions and/or Ulcers

Gastrointestinal Erosions and/or Ulcers

Japan
Shandong Luoxin Pharmaceutical Group Stock Co.,...

Completed

Efficacy and Safety of LXI-15028 Comparing With Esomeprazole in the Treatment of Erosive Esophagitis

Erosive Esophagitis (EE)

China
Takeda

Completed

Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)

Gastroesophageal Reflux

Belgium, Bulgaria, Poland, Estonia, United Kingdom, Czechia
Baylor Breast Care Center
AstraZeneca

Terminated

Nexium Study To Suppress Nausea During Chemotherapy (NEXIUM)

Nausea

United States
Baskent University Ankara Hospital

Completed

The Effect of Esomeprazole on Type 2 Diabetes

Diabetes Mellitus, Type 2
Livzon Pharmaceutical Group Inc.

Completed

Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese Patients

Gastroesophageal Reflux Disease
Eisai Inc.

Completed

Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

Chile, Canada, United States, Estonia, India, Hungary, Bulgaria, Croatia, Australia, Lithuania, Latvia, Argentina, France, Germany
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized Males

Pharmacokinetics of ASP8477 | Pharmacodynamics of ASP8477

France, Belgium
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Efficacy and Safety of L-Pantoprazole Sodium Injection to Treat Upper Gastrointestinal Ulcer Bleeding

Bleeding Gastric Ulcer | Bleeding Duodenal Ulcer

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing a Pantoprazole Formulation to the Currently Marketed Tablet for GERD and Erosive Esophagitis

Gastroesophageal Reflux | Esophagitis

United States
AstraZeneca

Completed

Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD Patients (MAESTRO)

GERD

France
AstraZeneca

Completed

Study of Intragastric pH Profile After 5 Days Pantoprazole 40 mg iv Followed by Oral Esomeprazole 40 mg po or Oral Pantoprazole 40 mg po

Healthy

United States
AstraZeneca

Completed

Esomeprazole in PPI Failures - IMPROVE

Gastroesophageal Reflux Disease

Sweden
Carlos Roberto Simons-Linares

Recruiting

OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers (OPEN-IT)

Marginal Ulcer

United States
Onconic Therapeutics Inc.

Recruiting

JP-1366 20mg Versus Esomeprazole 40mg in Patients With Erosive Esophagitis

Erosive Esophagitis

Korea, Republic of
Universitaire Ziekenhuizen KU Leuven

Completed

PPI and Microbiome in Healthy Volunteers and Functional Dyspepsia

Dysbiosis

Belgium
Celgene

Completed

Relative Bioavailability Study of CC-292

Healthy Volunteers

United States
Sihuan Pharmaceutical Holdings Group Ltd.

Completed

A Phase 2 Randomised Controlled Trial to Evaluate Efficacy and Safety of Anaprazole in Patients With Duodenal Ulcers.

Duodenal Ulcer，DU

China
Kaohsiung Veterans General Hospital.

Completed

On-demand PPI Therapy is Effective on Controlling Symptoms in Patients With Barrett's Esophagus.

Barrett Esophagus | Reflux | Proton Pump Inhibitor | Symptom
First Affiliated Hospital, Sun Yat-Sen University

Completed

The Primary Symptoms of GERD(Gastroesophageal Reflux Disease) in Chinese Outpatients in Gastroenterology Department

Gastroesophageal Reflux

China
Indiana University

Terminated

The Effects of Dexlansoprazole for the Treatment of Throat-Related Reflux

Laryngopharyngeal Reflux

United States
Takeda

Completed

A Study to Evaluate the Bioequivalence of Single Oral Dose of Esomeprazole Capsule and Tablet Formulation in Healthy Participants

Healthy Participants

United States
Pfizer

Completed

Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment

Heartburn

United States
Ahn-Gook Pharmaceuticals Co.,Ltd

Unknown

S-pantoprazole 10mg Phase III Clinical Study

Non Erosive Reflux Disease

Korea, Republic of

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