Search clinical trials for: rGLP-1 protein

Total 27245 results

GlaxoSmithKline

Completed

A Study of the Pharmacokinetics of Albiglutide in Normal and Renally Impaired Subjects.

Diabetes Mellitus, Type 2

United States, South Africa
GlaxoSmithKline

Completed

Albiglutide Glucose Clamp Study in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
GlaxoSmithKline

Withdrawn

A Study to Evaluate Pharmacokinetics, Safety and Efficacy of Albiglutide in Pediatric Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
GlaxoSmithKline
PPD

Withdrawn

Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2
GlaxoSmithKline

Completed

Safety and Efficacy of Albiglutide in Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, United Kingdom, Korea, Republic of, Peru, South Africa, India
GlaxoSmithKline

Completed

Safety and Efficacy Study of Albiglutide in Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Mexico, South Africa
GlaxoSmithKline

Completed

Pharmacokinetics/Pharmacodynamics of Albiglutide

Diabetes Mellitus, Type 2

United States
GlaxoSmithKline

Completed

A Study to Determine the Efficacy and Safety of Albiglutide as Compared With Liraglutide.

Diabetes Mellitus, Type 2

United States, Peru, Israel, Australia, United Kingdom, Korea, Republic of, Spain, Philippines
GlaxoSmithKline

Terminated

Extension to Study 200952 to Evaluate the Long-term Safety, Tolerability and Pharmacodynamics of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus Subjects

Diabetes Mellitus, Type 2

United States
GlaxoSmithKline

Completed

Out-Patient Study in Patients With Type 2 Diabetes Mellitus Who Are Taking no Diabetes Medication or Metformin Only

Diabetes Mellitus, Type 2

United States, Dominican Republic, Chile
GlaxoSmithKline

Completed

A Drug Interaction Study With Albiglutide and Warfarin

Diabetes Mellitus, Type 2

United States
University of Copenhagen
Gentofte Hospital, Denmark

Recruiting

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function (H-21044858)

Incretin Effect

Denmark
Ludwig-Maximilians - University of Munich
German Research Foundation; Merck Sharp & Dohme LLC

Completed

Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans

Hyperglycemia

Germany
GlaxoSmithKline

Completed

A Study to Determine the Safety and Efficacy of Albiglutide in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Russian Federation, United Kingdom, South Africa
GlaxoSmithKline
Duke Clinical Research Institute

Completed

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Argentina, Germany, Poland, Russian Federation, Spain, Taiwan, Czechia, Hungary, Italy, Ukraine, Belgium, Netherlands, South Africa, Sweden, Thailand, Korea, Republic of, Mexico, Bulgaria, Hong Kong, Peru, Philippines, Gree... and more
Zealand Pharma
Profil Institut für Stoffwechselforschung GmbH

Recruiting

A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Safety and Tolerability

Germany
GlaxoSmithKline

Completed

Albiglutide Versus Placebo in Insulin-treated Subjects With New-onset Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

Spain, Italy, France, Germany, United Kingdom
GlaxoSmithKline

Completed

A Study Evaluating the Effect of Albiglutide on Gallbladder Emptying in Healthy Subjects

Diabetes Mellitus, Type 2

United States
Zealand Pharma

Completed

A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Healthy

Germany
GlaxoSmithKline

Completed

Dose Ranging Study of Albiglutide in Japanese Subjects

Diabetes Mellitus, Type 2

Japan
University Hospital Tuebingen
Merck Sharp & Dohme LLC

Withdrawn

Characterization of Beta Cell Failure

Diabetes | Metabolic Syndrome

Germany
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Modulation of Human Myocardial Metabolism by GLP-1 Dose Response

Healthy | Type 2 Diabetes Mellitus

United States
University of Chicago

Completed

Incretin Regulation of Insulin Secretion in Monogenic Diabetes

Monogenic Diabetes

United States
Danone North America

Completed

Comparison of Plant and Animal Proteins on Amino Acid Concentrations

Healthy Resistance-Trained Males

Canada
GlaxoSmithKline
Wake Forrest Baptist Health

Terminated

An Exploratory Study on the Effects of Repeat Doses of Albiglutide Compared to Exenatide on Gastric Myoelectrical Activity and Gastric Emptying in Type 2 Diabetes Mellitus Subjects

Diabetes Mellitus, Type 2

United States
University of Mississippi Medical Center

Recruiting

Effect of GLP-1 Receptor Agonists on Trabecular Bone Score

Diabetes Mellitus, Type 2 | Osteoporosis, Postmenopausal

United States
Mayo Clinic
Merck Sharp & Dohme LLC

Completed

GLP1R Polymorphisms and Response to GLP1

Diabetes

United States
Athenex, Inc.

Completed

Safety, Tolerability & PK of KX2-361 in Subjects w Adv. Malignancies Refractory to Conventional Therapies

Advance Malignancies

United States
Papworth Hospital NHS Foundation Trust

Completed

Human Vasodilatory Effect of GLP-1

Angina, Stable | Type2 Diabetes | Coronary Stenosis
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Glucagon-Like Peptide-1 (GLP-1) Suppression of Alpha Cell Secretion in Type 2 Diabetes Mellitus (T2DM)

Hyperglycemia | Glucose Intolerance | Hyperglucagonemia
Aarhus University Hospital Skejby
Aarhus University Hospital; University of Aarhus

Completed

Effect of 48 Hours of Treatment With the Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure

Heart Failure, Congestive

Denmark
GlaxoSmithKline

Completed

A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.

Diabetes Mellitus, Type 2

United States, Germany, Peru, Israel, Taiwan, Australia, Russian Federation, United Kingdom, Korea, Republic of, Spain, Brazil, Colombia, India, Philippines, South Africa
GlaxoSmithKline

Completed

A Monotherapy Study to Evaluate the Efficacy and Safety of 2 Dose Levels of Albiglutide in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

Japan
GlaxoSmithKline

Completed

Bioequivalence Study of Two Albiglutide Drug Products in Healthy Adult Subjects

Diabetes Mellitus, Type 2

United States
University of Copenhagen
The Danish Medical Research Council

Completed

The Interaction Between Appetite Hormones

Obesity

Denmark
CellMed AG, a subsidiary of BTG plc.

Terminated

GLP-1 CellBeads® for the Treatment of Stroke Patients With Space-occupying Intracerebral Hemorrhage

Intracerebral Hemorrhage (ICH)

Germany
Dasman Diabetes Institute

Recruiting

Relationship Between Improvement in Insulin Secretion and Decrease in HbA1c in GLP-1 RA Therapy in T2DM Patients

Diabetes Mellitus, Type 2

Kuwait
Mikkel Christensen
University of Copenhagen

Completed

GIP and GLP-1 in Type 1 Diabetes

Hypoglycemia

Denmark
Papworth Hospital NHS Foundation Trust

Unknown

GLP-1 Loading During Elective Percutaneous Coronary Intervention (GOLD-PCI)

Myocardial Infarction | Angina Pectoris | Coronary Heart Disease | Reperfusion Injury

United Kingdom
Johns Hopkins University

Terminated

Effect of GLP - 1 (7-36 Amide) on Myocardial Function Following Coronary Artery Bypass (CABG) Surgery (GLP-1 CABG)

CABG

United States
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Gene Polymorphisms on GLP-1 Receptor Agonists Response in Patients With T2DM

Type 2 Diabetes Mellitus

China
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight

Obesity

United States
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Unknown

Intact Vagal Innervation and Glucagon-like Peptide-1 (GLP-1) Effects

Vagotomy, Truncal

Denmark
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Completed

Effects of Oral GLP-1 on Glucose Homeostasis and Appetite Profile in Healthy Male Subjects

Glucose Homeostasis

Switzerland
GlaxoSmithKline

Completed

A Drug Interaction Study of Albiglutide and Digoxin

Diabetes Mellitus, Type 2

United States
University of Copenhagen
Copenhagen University Hospital, Hvidovre

Recruiting

Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.

Obesity

Denmark
University of Missouri-Columbia
American Society for Metabolic and Bariatric Surgery

Recruiting

Impact GLP-1 Agonists Following Bariatric

Hypertension | Diabetes Mellitus | Metabolic Syndrome | Morbid Obesity | Obstructive Sleep Apnea of Adult

United States
Danish Headache Center

Unknown

Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon Like Peptide-1 in Humans

Headache, Migraine

Denmark
Rigshospitalet, Denmark

Completed

Hyperglycemia and the Extra-pancreatic Effect of Incretins

Extra-pancreatic Incretin Effect | Glucose Effectiveness

Denmark
GlaxoSmithKline
PPD

Completed

Safety and Efficacy of Albiglutide + Insulin Glargine Versus Insulin Lispro + Insulin Glargine Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Spain, Germany, Hungary, Italy, Philippines, France, United States, Mexico, Brazil, South Africa, Korea, Republic of, Canada, Poland, United Kingdom

Search clinical trials for: rGLP-1 protein

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