Search clinical trials for: recombinant human insulin

Total 7532 results

Shire
Takeda Development Center Americas, Inc.

Active, not recruiting

An Efficacy and Safety Study of HGT-1110 in Participants With Metachromatic Leukodystrophy

Metachromatic Leukodystrophy (MLD)

Denmark, Germany, Japan, Australia, France, Brazil, Czechia
Shire

Completed

Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients

Mucopolysaccharidosis (MPS)

United Kingdom, Netherlands
Shire

Completed

Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease

Sanfilippo Syndrome

United States, Spain, United Kingdom, Argentina, France, Germany, Italy, Netherlands
FDA Office of Orphan Products Development
Children's Hospital of Philadelphia

Completed

Short Term Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism

Hyperinsulinism
Julphar Gulf Pharmaceutical Industries
Parexel; Profil Institut für Stoffwechselforschung GmbH

Completed

Pharmacokinetic (PK) Bioequivalence and Pharmacodynamics of Julphar Insulin R and Huminsulin® Normal

Diabetes Mellitus

Germany
Wockhardt

Terminated

Immunosafety Study of Recombinant Human Insulins in Type 1 Diabetics

Type I Diabetes

United States, India
Ming Hou
Peking Union Medical College Hospital; Cancer Institute and Hospital, Chinese... and other collaborators

Completed

Recombinant Human Thrombopoietin in Combination With Rituximab in Immune Thrombocytopenia (ITP)

Purpura | Idiopathic Thrombocytopenic Purpura

China
Novo Nordisk A/S

Completed

Comparison of the Blood Sugar Lowering Effect of Biphasic Insulin Aspart 30 and Insulin Glargine Both Combined With Metformin and Glimepiride in Chinese and Japanese Subjects With Type 2 Diabetes New to Insulin Treatment (EasyMix)

Diabetes Mellitus, Type 2 | Diabetes

Japan, China
Novo Nordisk A/S

Completed

Observational Study to Investigate the Efficacy and Safety of Human Insulin or Insulin Analogue Treatments in Type 2 Diabetes Subjects

Diabetes Mellitus, Type 2 | Diabetes

China
State University of New York - Downstate Medical...

Terminated

Pilot: Insulin Sensitivity/Management in Hyperglycemic Patients in Perioperative Period ESRD/Non-ESRD

Diabetes Mellitus | End-Stage Renal Disease

United States
BioMarin Pharmaceutical

Completed

A Safety, Tolerability, and Efficacy Study of Intracerebroventricular BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease | CLN2 Disorder

United States, Germany, Italy, United Kingdom
Shanghai Gebaide Biotechnology Co., Ltd.

Unknown

A Phase III Trial of Recombinant Human Apo-2 Ligand for Injection

Non-small-cell Lung Cancer (NSCLC) Stage IV

China
Genzyme, a Sanofi Company
BioMarin/Genzyme LLC

Terminated

A Study of the Effect of Aldurazyme® (Laronidase) Treatment on Lactation in Female Patients With Mucopolysaccharidosis I (MPS I) and Their Breastfed Infants

Mucopolysaccharidosis I | Hurler's Syndrome | Hurler-Scheie Syndrome | Scheie

Italy
Shire

Terminated

An Extension Study to Determine Safety and Efficacy for Pediatric Patients With MPS Type IIIA Disease Who Participated in Study HGT-SAN-093.

Sanfilippo Syndrome | Mucopolysaccharidosis (MPS)

United States, United Kingdom, Spain, Germany, France, Italy, Netherlands
Beijing Northland Biotech. Co., Ltd.

Completed

A Phase 1a Study of Thymosin Beta 4 in Healthy Volunteers

Healthy

China
Beijing Northland Biotech. Co., Ltd.

Completed

A Phase 1b Study of Thymosin Beta 4 in Healthy Volunteers

Healthy

China
University of Miami
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of Leptin Replacement in Children

Obesity | Diabetes | Metabolic Syndrome

United States
Alexion Pharmaceuticals

Completed

Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)

Mucopolysaccharidosis IIIB

United States, United Kingdom, Spain
BioMarin Pharmaceutical

Approved for marketing

A Multicenter, Multi-national Open-label Program to Provide BMN 190 to Patients Diagnosed With CLN2 Disease

CLN2 Disease

United Kingdom, United States, Germany, Italy
Green Cross Corporation
ICON Clinical Research

Terminated

Safety Study of MG1102 in Patients With Solid Tumors

Solid Tumors

Korea, Republic of
Protalix

Completed

Safety and Pharmacokinetics of Oral PRX-112 in Gaucher Disease Patients

Gaucher Disease

Israel
Patricia I. Dickson, M.D.
The Ryan Foundation

Terminated

Extension Study of Intrathecal Enzyme Replacement Therapy for MPS I

Mucopolysaccharidosis I | Scheie Syndrome | Lysosomal Storage Disease | Spinal Cord Compression | Hurler-Scheie Syndrome

Finland, United States
NHS Greater Glasgow and Clyde

Completed

Efficacy and Safety of R-hLH (Luveris ®) Priming Prior to R-HFSH Treatment in Infertile Women Undergoing IVF-ET

Infertility

Denmark, France, United Kingdom
AM-Pharma

Terminated

(Revival) Study to Investigate the Efficacy and Safety of Alkaline Phosphatase in Patients With Sepsis-Associated AKI

Acute Kidney Injury Due to Sepsis

Belgium, Spain, United States, Austria, Denmark, France, United Kingdom, Finland, New Zealand, Australia, Germany, Canada, Netherlands, Ireland, Japan
Zensun Sci. & Tech. Co., Ltd.

Active, not recruiting

Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure

Chronic Systolic Heart Failure

China
Shire

Completed

Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD) (IDEAMLD)

Metachromatic Leukodystrophy (MLD)

Australia, Denmark, Japan, France, Germany
The First Affiliated Hospital of Guangzhou Medical...

Withdrawn

Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19

COVID-19

China
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI); Sanofi

Withdrawn

Intensive Glycemic Control on Infectious Morbidity In Patients With Acute Leukemia

Hyperglycemia | Leukemia

United States
Eli Lilly and Company

Completed

A Study of LY2605541 (Insulin Peglispro) and Human Insulin Concentrations in Fat Tissue

Diabetes Mellitus, Type 1

Austria
University of Miami
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of Human Leptin Replacement

Obesity | Diabetes | Metabolic Syndrome

United States
Daiichi Sankyo, Inc.

Completed

Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure

Heart Failure, Congestive | Heart Decompensation | Left Ventricular Failure | Myocardiopathies | Systolic or Diastolic Left Ventricular Dysfunction

United States, Canada
Genzyme, a Sanofi Company

Completed

High Dose or High Dose Frequency Study of Alglucosidase Alfa

Glycogen Storage Disease Type II (GSD-II) | Pompe Disease | Glycogenesis 2 Acid Maltase Deficiency

United States, Canada, Australia
TNO
Alloksys Life Sciences B.V.

Completed

Microdose and First-In-Human (FIH) Study of Recombinant Human Placental Alkaline Phosphatase (hRESCAP)

Healthy

Netherlands
Novo Nordisk A/S

Completed

Efficacy and Safety of Insulin Aspart in MDI or CSII in Children Below 7 Years of Age With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Poland
Novo Nordisk A/S

Completed

Efficacy and Safety of Insulin Aspart vs. Human Insulin During Pregnancy by Women With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

United Kingdom, Denmark, Canada, France, Netherlands, Austria, Israel, Finland, Russian Federation, Croatia, Bulgaria, Poland, Ireland, Spain, Norway, Greece, Argentina, Germany
Mannkind Corporation

Completed

Comparison of the Effect on the Glucose Infusion Rates Between Inhaled Technosphere Insulin and a Subcutaneous Injection of Regular Human Insulin

Healthy
Novo Nordisk A/S

Completed

Comparison of the Pharmacodynamics and Pharmacokinetics of Insulin Aspart and Human Insulin in Elderly People With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Germany
Novo Nordisk A/S

Completed

Self-control Trial to Evaluate the Remission Rate in Newly Diagnosed Type 2 Diabetes Patients After Treatment With Insulin Aspart

Diabetes Mellitus, Type 2 | Diabetes

China
University of Giessen
Sanofi

Completed

Comparison of Insulin Glargine and NPH Insulin at Night and at Hypoglycemia in Type 2 Diabetes (ClampHOE901)

Diabetes

Germany
Novo Nordisk A/S

Terminated

Safety of Inhaled Human Insulin in Subjects With Diabetes Mellitus and Chronic Obstructive Pulmonary Disease (COPD) (iINHALE 8)

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1 | Chronic Obstructive Pulmonary Disease

Slovakia, Argentina, India, Turkey, Romania, Taiwan, Thailand
Eli Lilly and Company
Alkermes, Inc.

Completed

A Study for Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

NovoLet® Acceptance Study Within the Hospital Practise in Indonesia

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Indonesia
Novo Nordisk A/S

Terminated

Changing Diabetes in Children (CDiC)

Diabetes | Diabetes Mellitus, Type 1

India
Novo Nordisk A/S

Completed

Insulin Aspart vs. Insulin Lispro vs. Regular Insulin in Paediatric Population

Diabetes | Diabetes Mellitus, Type 1

United States
Hypoglycaemia Research Group
Rigshospitalet, Denmark

Completed

The Impact of Renin-angiotensin System on Brain Activation During Hypoglycaemia in Healthy Men, a PET Study

Hypoglycemia | Cognitive Impairment

Denmark
Novo Nordisk A/S

Completed

Observational Study of the Predictability of Levemir® in Terms of Metabolic Control, Change of Body Weight and Hypos

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Slovakia
Novo Nordisk A/S

Completed

Effect of Exercise on the Absorption of Inhaled Human Insulin in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Austria
Christchurch Women's Hospital

Completed

Study of a Model-based Approach to Blood Glucose Control in Very-low-birthweight Neonates

Hyperglycaemia

New Zealand
Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 1 Diabetes Mellitus.

Diabetes Mellitus, Type 1

United States, Canada
Novo Nordisk A/S

Completed

Pharmacokinetics of Insulin Detemir in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Japan

Search clinical trials for: recombinant human insulin

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