Search clinical trials for: rhNGF 60 µg/ml eye drops solution

Total 547 results

Dompé Farmaceutici S.p.A

Completed

A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP) (Lumos)

Retinitis Pigmentosa

Italy
Ospedale San Raffaele
Dompé Farmaceutici S.p.A

Completed

Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema (NEMO)

Retinitis Pigmentosa | Cystoid Macular Edema

Italy
Dompé Farmaceutici S.p.A
Covance

Completed

Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers (NGF0112)

Healthy

Switzerland, United Kingdom
Dompé Farmaceutici S.p.A

Completed

Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. (REPARO)

Keratitis | Neurotrophic Keratitis | Corneal Ulcer

Germany, Italy, France, Poland, Spain, United Kingdom
Dompé Farmaceutici S.p.A
Cross Research S.A.

Completed

Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye

Dry Eye Syndrome

Austria
Merz Pharmaceuticals GmbH

Completed

Safety and Tolerability of MRZ-99030 Eye Drops in Healthy Volunteers and Glaucoma Patients

Healthy Volunteers and Glaucoma Patients

Germany
Alcon Research

Completed

Acute Comfort and Blur Profile of a Lubricant Eye Drop Versus a Marketed Eye Ointment

Dry Eye
Jadran Galenski laboratorij d.d.

Completed

Comparative Study of Dorzotimol Eye Drops, 20 mg/mL + 5 mg/mL Versus Cosopt® Eye Drops, 20 mg/mL + 5 mg/mL

Primary Open Angle Glaucoma of Both Eyes

Russian Federation
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

A Phase II Clinical Trial to Evaluate the Efficacy and Safety of ZKY001 Eye Drops (TPRK)

Corneal Epithelium Defect

China
Alcon Research

Completed

Formula Identification (FID) 114657 in Contact Lens Wearers

Refractive Error
Allergan

Completed

Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease

Dry Eye Syndromes

United States
Alcon Research

Completed

Efficacy of Systane Ultra in Post Menopausal Women With Dry Eye

Post Menopausal Dry Eye Subjects
Alcon Research

Completed

Acute Comfort of Lubricant Eye Drop FID 111421

Dry Eye
Alcon Research

Completed

Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Health

Ocular Hypertension | Open Angle Glaucoma
Dompé Farmaceutici S.p.A

Completed

A 2 Weeks Study to Evaluate Tolerability, Safety, Permanence on the Ocular Surface and Efficacy of Two Concentrations of Lubricin Eye Drops Versus Sodium Hyaluronate 0.18% Eye Drops in Patients With Ocular Discomfort Following Refractive Surgery

Ocular Discomfort

Italy
Johnson & Johnson Vision Care, Inc.

Completed

Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients

Dry Eye

United States
Alcon Research

Completed

An Evaluation of the Daytime Use of an Investigational Lubricant Eye Drop

Dry Eye
Alcon Research

Completed

An Evaluation of the Nighttime Retention of Effect of an Investigational Lubricant Eye Drop (FID 115958D)

Dry Eye
Ophthalmic Consultants of Connecticut

Unknown

Patient Satisfaction and Tear Osmolarity With the Use of Blink Tears, Blink Gel Tears and Systane Balance

Dry Eye

United States
Alcon Research

Completed

Residence Time Evaluation of Systane Ultra Lubricant Eye Drops vs. Hialid and Saline

Dry Eye Syndrome
Alcon Research

Completed

Residence Time Evaluation of Marketed OTC Ophthalmic Products

Dry Eye
Medical University of Vienna

Completed

Influence of Three Different Formulations of Lachrymal Substitutes on Tear Film Thickness and Other Signs and Symptoms in Patients With Moderate to Severe Dry Eye Syndrome

Dry Eye Syndromes

Austria
Hai Yen Eye Care
Brien Holden Vision Institute

Completed

Myopia Control With Novel Eye Drops

Myopia

Vietnam
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Recruiting

Evaluating the Efficacy and Safety of ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects

Corneal Defect

China
Alcon Research

Completed

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Vanderbilt-Ingram Cancer Center

Terminated

Effect of Artificial Tears on Radioiodine Levels in the Nasolacrimal Duct System

Thyroid Carcinoma | Radioactive Iodine Level

United States
Dompé Farmaceutici S.p.A

Completed

A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye

Dry Eye Syndrome

United States
Alcon Research

Completed

Acute Comfort and Blur of Systane and Optive

Dry Eye
Alcon Research

Completed

Acute Comfort and Blur Profile of a Lubricant Eye Drop Versus a Marketed Lubricant Eye Gel

Dry Eye
Alcon Research

Completed

Efficacy Study of Travoprost APS Versus TRAVATAN

Ocular Hypertension | Open Angle Glaucoma
Alcon Research

Completed

Acute Comfort and Blurring Profile Evaluation of Marketed Lubricant Eye Drops

Dry Eye

United States
Allgenesis Biotherapeutics Inc.

Completed

A Study of the Response to AG-86893 in Patients With Pterygium Hyperemia (SURPH)

Pterygium

Australia
Fovea Pharmaceuticals SA

Completed

Safety and Efficacy Study of Topical Administration of FOV2304 (High Dose or Low Dose) for the Treatment of Center-involving Clinically Significant Macular Edema Associated With Diabetic Retinopathy

Diabetic Macular Edema

United States, Australia, Belgium, Czech Republic, France, Germany, Israel, Italy, Poland, Spain
Alcon Research

Completed

The Effect of Systane Ultra Lubricant Eye Drops (FID 112903) on Visual Performance

Dry Eye

United States
pH Pharma

Completed

PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects

Healthy Volunteer

Korea, Republic of
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of SHR8058 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction

Treatment of Dry Eye Disease With Meibomian Gland Dysfunction

China
Alcon Research

Completed

Systane Hydration in Subjects Undergoing Cataract Surgery

Cataract | Dry Eye Disease

Spain
Tufts Medical Center

Completed

The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED

Dry Eye Disease

United States
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects in a Phase Ⅱ Clinical Trial

Corneal Epithelial Defect

China
Alcon Research

Completed

Acute Comfort of Lubricant Eye Drops FID 112903

Dry Eye

United States
Alcon Research

Completed

Acute Comfort and Blur of Systane Ultra and Systane

Dry Eye

United States
Tiedra Farmacéutica SL
Hospital Universitario Principe de Asturias

Unknown

Efficacy and Tolerance of Hypertonic Sodium Chloride (NaCl 5%) Eye Drops Without Preservatives in Corneal Edema

Corneal Edema

Spain
Jiangsu HengRui Medicine Co., Ltd.

Completed

Efficacy and Safety of SHR8028 Eye Drops for the Treatment of Dry Eye Disease

Dry Eye Disease

China
Tarsier Pharma

Completed

A Study of TRS01 in Participants With Post-surgical Ocular Inflammation

Post Surgical Ocular Inflammation

United States
Johnson & Johnson Vision Care, Inc.

Completed

Clinical Evaluation of Two Marketed Artificial Tears in Non-contact Lens Wearing Patients

Visual Acuity

United Kingdom
Quan Dong Nguyen
Global Ophthalmic Research Center (GORC)

Recruiting

Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study (LION)

Inflammation | Uveitis

United States
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

The Germinal Peptide Eye Drops in Healthy Volunteers in a Clinical Study

Corneal Defect

China
Horus Pharma

Completed

Evaluation of the Efficacy and Safety of DM05 Versus Optive™ on the Treatment of Moderate to Severe Ocular Dryness

Dry Eye
Alcon Research

Completed

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Withdrawn

Comparative Efficacy of SYSTANE® ULTRA vs Optive™ in Improving Tear Film Break-up Time

Dry Eye

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