Search clinical trials for: signalling change

Total 10387 results

Queen's University, Belfast
University of Warwick; University of Birmingham

Completed

Parents Resources for Decreasing the Incidence of Change Triggered Temper Outbursts (PREDICTORS)

Child Behavior

United Kingdom
Longeveron Inc.
The University of Texas Health Science Center, Houston; National Heart, Lung... and other collaborators

Recruiting

Evaluation of Lomecel-B™ Injection in Patients With Hypoplastic Left Heart Syndrome (HLHS): A Phase IIb Clinical Trial. (ELPIS II)

Hypoplastic Left Heart Syndrome

United States
Chulalongkorn University
King Chulalongkorn Memorial Hospital

Recruiting

Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG (CMD03DIPG)

Diffuse Intrinsic Pontine Glioma | DIPG Brain Tumor

Thailand
University Hospital, Montpellier

Recruiting

Immune Activation as a Cause of Insulin Resistance in Adults Living With HIV-1 on Effective Antiretroviral Therapy (MetACTIVIH)

HIV Infections

France
Assiut University

Completed

Expression of EPK in Recurrent Miscarriage (EPK-RM)

Recurrent Miscarriage

Egypt
Washington University School of Medicine

Completed

The Impact of Legumes vs Corn-soy Flour on Environmental Enteric Dysfunction in Rural Malawian Children 1-3 Year Olds

Environmental Enteropathy

Malawi
West Cancer Center
Puma Biotechnology, Inc.; Celcuity Inc

Active, not recruiting

Evaluating the Efficacy of Neratinib on Live Cell HER2 Signaling Transduction Analysis Positive Triple Negative Breast (FACT-2)

Triple Negative Breast Cancer | HER2-positive Breast Cancer | Early-stage Breast Cancer

United States
Drugs for Neglected Diseases
Bayer; Bill and Melinda Gates Foundation

Completed

Safety, Tolerability and PK of Multiple-ascending Doses of Emodepside

Filariasis

United Kingdom
National Cancer Institute (NCI)

Completed

RO4929097 in Treating Patients With Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
National Cancer Institute (NCI)

Completed

Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer

Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
National Cancer Institute (NCI)

Terminated

Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced, Metastatic, or Recurrent Triple Negative Invasive Breast Cancer

Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Triple-negative Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer | Estrogen Receptor-negative Breast Cancer | Progesterone Receptor-negative Breast Cancer | HER2-negative Breast Cancer

Canada
UNC Lineberger Comprehensive Cancer Center

Recruiting

Physical Function During ARSI Treatment

Advanced Prostate Carcinoma

United States
National Cancer Institute (NCI)
M.D. Anderson Cancer Center

Terminated

RO4929097 in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Recently Completed Treatment With Front-Line Chemotherapy

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Memorial Sloan Kettering Cancer Center

Completed

Proximal Molecular Effects of Concurrent Chemoradiotherapy on Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

United States
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Worksite Program to Prevent Weight Gain Among Bus Drivers

Heart Diseases | Cardiovascular Diseases | Obesity

United States
National Cancer Institute (NCI)

Withdrawn

RO4929097 in Treating Patients With Stage IIIB, Stage IIIC, or Stage IV Melanoma That Can Be Removed by Surgery

Stage IV Melanoma | Stage IIIB Melanoma | Stage IIIC Melanoma

United States
National Cancer Institute (NCI)

Completed

Gamma-Secretase Inhibitor RO4929097 in Treating Patients With Metastatic or Unresectable Solid Malignancies

Unspecified Adult Solid Tumor, Protocol Specific

Canada
National Cancer Institute (NCI)

Terminated

RO4929097 in Treating Patients With Recurrent Invasive Gliomas

Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Adult Brain Stem Glioma

Canada
Chulalongkorn University

Unknown

Effectiveness of Modified Health Belief Model Based Intervention to Reduce Body Mass Index

Overweight
German Heart Institute
Deutsche Stiftung für Herzforschung; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Recruiting

Microvascular Cardiac Allograft Vasculopathy Trial (mCAV)

Cardiac Allograft Vasculopathy

Germany
University of California, Los Angeles

Recruiting

Work Time Schedule Changes for Nurse Managers

Work-Related Condition

United States
National Cancer Institute (NCI)

Terminated

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Unspecified Adult Solid Tumor, Protocol Specific | HER2-positive Breast Cancer | Recurrent Melanoma | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer | Recurrent Breast Cancer | Estrogen Receptor-negative Breast... and other conditions

United States
Lithuanian University of Health Sciences
University of Groningen; Research Council of Lithuania

Unknown

Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma (ECMA)

Extracellular Matrix Alteration | Allergic Asthma | Airway Remodelling

Lithuania
Ludwig-Maximilians - University of Munich
Child Health Foundation; Johnson & Johnson Citizenship Trust, in cooperation... and other collaborators

Completed

Population-based Intervention to Promote Health in Elementary Schools

Health Promotion
Children's Hospital of Fudan University
Xiamen Children's Hospital; Shenzhen Children's Hospital; Anhui Province Children...

Completed

Frequence of Dressing Change and Bacterial Colonization in Pediatric Intensive Care Unit

Bacterial Infections

China
Tri-Service General Hospital

Completed

Three-month Chan-Chung Qigong Improves Physical Function Performance and Quality of Life

Cognitive Dysfunction | Exercise Training | Cognitive Decline | Cognitive Aging | Grip | Physical Endurance
Scripps Center for Integrative Medicine

Unknown

Lifestyle Change Program in Elderly Patients With Heart Failure

Heart Failure

United States
National Cancer Institute (NCI)

Terminated

RO4929097 Before Surgery in Treating Patients With Pancreatic Cancer

Adenocarcinoma of the Pancreas | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
University of Aberdeen
University of Jazan

Completed

Weight Gain in First-year University Students

Obesity

United Kingdom
University of Bradford

Completed

Reducing Knee Compression When Sleeping in Those With Knee OA

Osteoarthritis, Knee

United Kingdom
Georgia State University
Arizona State University

Enrolling by invitation

Personalized Integrated Alcohol and Sexual Assault Prevention Among College Students (+Change)

Alcohol Drinking | Sexual Assault

United States
Fundacio d'Investigacio en Atencio Primaria Jordi...
Universitat de Vic

Active, not recruiting

Do the Symptoms of Chronic Constipation Improve With a Primary Care Programme Based on Behavioural Re-education and Abdominal Massage?

Constipation Chronic Idiopathic

Spain
Federal University of São Paulo

Completed

Oral Pilocarpine in the Treatment of the Dry Eye of Patients With Sjogrens Syndrome

Dry Eye

Brazil
National Cancer Institute (NCI)

Completed

RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States, Canada
Children's Mercy Hospital Kansas City

Completed

Mic-Key Versus Mini One Family Preference Comparison (MicKeyVMini)

Gastroesophageal Reflux | Family Satisfaction | Feeding Disorder

United States
Tung Wah College
The Hong Kong Polytechnic University; University of Southampton

Not yet recruiting

E-health Brisk Walking in Older People With Cognitive Frailty

Cognitive Frailty
Dokuz Eylul University

Not yet recruiting

Lifestyle Change in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome
California Polytechnic State University-San Luis...
The Miriam Hospital; Bradley Hospital

Recruiting

Feasibility of Cardiovascular Health Intervention Within Evidence-based Home Visiting

Obesity | Diet, Healthy | Inactivity, Physical

United States
Fundacion Podoactiva

Completed

Baropodometric Parameters Variation With Body Weight Loss

Obesity | Postural Imbalance

Spain
University of British Columbia

Unknown

Small Steps for Big Changes: A Lifestyle Program to Reduce the Risk of Developing Type 2 Diabetes

PreDiabetes

Canada
University of Turin, Italy
Ministry of Health, Italy

Unknown

Protective Ventilatory Strategy in Potential Organ Donors

Mechanical Ventilation

Italy
Umeå University
Kuopio University Hospital; Sahlgrenska University Hospital, Sweden; Uppsala...

Terminated

Using Cerebrospinal Fluid Dynamics to Optimize Treatment of Idiopathic Normal Pressure Hydrocephalus (PULSE-OPT)

Hydrocephalus, Normal Pressure

Finland, Sweden
Centre Hospitalier Universitaire de Nīmes
University Hospital, Montpellier

Recruiting

Study of the Impact of Frequency of Changing PICCline Dressings in Patients With Acute Leukemia (LEUKA-PICC)

Leukemia

France
Rebecca Tavernier

Withdrawn

Augmentation of Standard Psychotherapy With a Habit Change App

Depression | Diabetes | Anxiety Disorders | Substance Use Disorders
Liverpool John Moores University
University of Liverpool; Dublin City University

Unknown

A Multi-component Physical Activity Intervention for Adolescent Girls

Exercise

Ireland, United Kingdom
Stanford University
Johns Hopkins Bloomberg School of Public Health

Completed

Using Behaviour Change Messaging to Improve Communal Toilets in Dhaka, Bangladesh (WSUP)

Diarrhea

Bangladesh
Rambam Health Care Campus

Completed

The Effects of Position on the Oxygenation Instability of Premature Infants as Documented by SpO2 Histograms

Bronchopulmonary Dysplasia | Premature Infant

Israel
University of Pennsylvania

Completed

Behavioral Economics in Provider Incentive Design

Diabetes

Search clinical trials for: signalling change

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