Search clinical trials for: Sitagliptin and Metformin

Total 271746 results

Boehringer Ingelheim

Completed

Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects

Healthy

Germany
Children's Hospital Los Angeles

Terminated

Metformin and Transient Hyperglycemia

Hyperglycemia | Diabetes Mellitus | Insulin Resistance | Acute Lymphoblastic Leukemia

United States
GlaxoSmithKline

Completed

AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes

Non-Insulin-Dependent Diabetes Mellitus

Spain, Germany, Belgium, United Kingdom, Ireland, Netherlands, Italy, France, Mexico, Switzerland, Lithuania
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Bristol-Myers Squibb

Completed

A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)

Type 2 Diabetes Mellitus
University of Jordan

Completed

Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan

Diabetes Mellitus, Type 2

Jordan
Peking University

Unknown

Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) (ECMTPneo)

Esophageal Squamous Cell Carcinoma

China
M.D. Anderson Cancer Center

Terminated

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Colorectal Carcinoma

United States
AstraZeneca
Parexel

Completed

Phase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single Components

Healthy Volunteers (Intended Indication: Type 2 Diabetes Mellitus)

Germany
GWT-TUD GmbH

Terminated

Risk of Nocturnal Hypoglycemia and Arrhythmias With Sitagliptin Versus Glimepiride in Patients With Type 2 Diabetes

Diabetes Mellitus Type 2

Germany
Merck Sharp & Dohme LLC

Completed

MK0431 (Sitagliptin) Pioglitazone Add-on Study for Patients With Type 2 Diabetes Mellitus (0431-055)(COMPLETED)

Type 2 Diabetes Mellitus
Boehringer Ingelheim

Completed

Bioavailability of BI 1356 BS and Metformin After Co-administration Compared to the Bioavailability of BI 1356 BS Alone and Metformin Alone in Healthy Male Volunteers

Healthy
AstraZeneca
Bristol-Myers Squibb

Completed

52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period

Type 2 Diabetes

Korea, Republic of, Russian Federation, United Kingdom, Vietnam, Germany, Hungary, Finland, Norway, Netherlands, Slovakia, India
Khoo Teck Puat Hospital

Completed

Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment

Type II Diabetes in Subjects BMI 27 to 32

Singapore
Zagazig University

Completed

Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Egypt
Solvay Pharmaceuticals

Completed

A Controlled-Study on the Effect of a Combination of Fenofibrate and Metformin on Weight Loss and Weight Loss-Maintenance, in Obese Patients.

Obesity

Finland
Second Affiliated Hospital, School of Medicine,...

Recruiting

Retrospective Analysis for Patients With Metabolic Syndrome

Metabolic Syndrome

China
King Edward Medical University

Completed

Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver

NAFLD

Pakistan
Boehringer Ingelheim
Eli Lilly and Company

Completed

Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Compared With Single Tablets

Healthy

United States
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
National Cancer Institute (NCI)

Recruiting

Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

Lung Carcinoma

United States, Canada
Chongqing Medical University

Completed

Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes

Diabetes

China
Assiut University

Recruiting

USE THE SYSTEMIC METFORMIN IN MELASMA

Melasma

Egypt
Hernando Gomez
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Enrolling by invitation

Safety and Feasibility of Metformin for Sepsis Induced AKI

Sepsis | Septic Shock | Acute Kidney Injury | Metformin

United States
Seoul National University Bundang Hospital

Completed

Initial Combination of Gemigliptin and Metformin on Microbiota Change (INTESTINE)

Diabetes

Korea, Republic of
Mannkind Corporation

Completed

Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Brazil, Spain, Argentina, Canada, Chile, Mexico, Poland, Russian Federation, Ukraine, Czech Republic
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (150 mg/850 mg) With Respect to the Individual Components of Canagliflozin (1 x 300 mg) and Metformin IR Tablets (2 x 850 mg) in Healthy Volunteers

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

Healthy

United States
Wake Forest University Health Sciences
University of South Florida; National Institute on Aging (NIA)

Recruiting

Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction (Met-PEF)

Heart Failure With Preserved Ejection Fraction

United States
PT. Pyridam Farma Tbk
PT Pharma Metric Labs

Completed

Bioequivalence Study of Metformin Hydrochloride 500 mg Film-Coated Tablets in Indonesia Healthy Subject

Drug Use

Indonesia
Sunovion

Completed

A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.

Schizophrenia

United States
Hager salah el din

Completed

Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment

Metastatic Breast Cancer

Egypt
Kristian Karstoft
University of Copenhagen

Completed

The Interaction Between Metformin and Acute Exercise

Diabetes Mellitus, Type 2 | Impaired Glucose Tolerance

Denmark
National Cheng-Kung University Hospital

Terminated

Metformin in Stage IV Lung Adenocarcinoma

Non-small Cell Lung Cancer

Taiwan
GlaxoSmithKline

Completed

Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies.

Diabetes Mellitus, Type 2

Spain, Germany, France, Austria, Italy
K. Marcinkowski University of Medical Sciences

Completed

Metformin in Gestational Diabetes Mellitus (MetGDM)

Insulin Resistance | Diabetes, Gestational

Poland
University of Oulu
University of Turku; University of Helsinki; Tampere University; University of...

Completed

The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS)

Toxemia | Polycystic Ovary Syndrome | Infertility | Miscarriage | Gestational Diabetes

Finland
Sherif S. Farag
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Acute Lymphoid Leukemia | Leukemia, Myelogenous, Chronic | Hematopoetic Myelodysplasia

United States
Amsterdam UMC, location VUmc
EU FP7: SAFEGUARD consortium

Completed

SAFEGUARD: Pleiotropic Effects of Incretin Based Therapies

Type 2 Diabetes

Netherlands
AstraZeneca

Completed

A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin

Type 2 Diabetes Mellitus

United States, Poland, Mexico, Hungary, Spain, Romania, South Africa, Denmark, Czechia, Sweden
RenJi Hospital

Not yet recruiting

The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics

Myocardial Fibrosis | Obesity | Type 2 Diabetes | Magnetic Resonance Imaging | Sodium-glucose Co-transporter-2 Inhibitor
Sun Yat-sen University

Not yet recruiting

The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer

Metastatic Prostate Cancer

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Recruiting

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

United States
Garvan Institute of Medical Research
National Health and Medical Research Council, Australia

Recruiting

Preventing Cognitive Decline With Metformin (MetMemory)

Cognitive Decline

Australia
National Cancer Institute (NCI)

Terminated

Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

Renal Cell Carcinoma | Renal Cell Cancer | Hereditary Leiomyomatosis

United States
Cynthia Calkin
Stanley Medical Research Institute

Completed

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder (TRIO-BD)

Bipolar Disorder

United States, Canada
University of Virginia

Completed

Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome (EJB044)

Metabolic Syndrome | Insulin Sensitivity

United States
Lars Christian Gormsen

Completed

Effects of Metformin on Hepatic FFA Metabolism

Type 2 Diabetes | Dyslipidemia
Virginia Commonwealth University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacogenetics of Metformin Action in PCOS

Polycystic Ovary Syndrome

United States

Search clinical trials for: Sitagliptin and Metformin

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