Search clinical trials for: subcutaneous tocilizumab

Total 1219 results

Hoffmann-La Roche

Completed

A Long-term Safety Extension Study of Tocilizumab in Brazilian Participants With Rheumatoid Arthritis (RA) Who Completed the Studies ML21530 and MA21488 (RITACT)

Arthritis, Rheumatoid

Brazil
Sanofi
Regeneron Pharmaceuticals

Completed

Single-dose Study to Describe the Safety of Sarilumab and Tocilizumab in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
University Health Network, Toronto
Janssen Inc.

Not yet recruiting

Plan Development for Giving Teclistamab in the Outpatient Setting

Multiple Myeloma | Relapsed Cancer | Refractory Cancer
Hoffmann-La Roche

Terminated

A Study to Evaluate Safety, Pharmacokinetics, and Preliminary Anti-tumor Activity of RO7444973 in Participants With Unresectable and/or Metastatic MAGE-A4-positive Solid Tumors

Solid Tumors

Belgium, United States, Australia, Denmark, Spain, United Kingdom
Assistance Publique - Hôpitaux de Paris
Chugai Pharmaceutical

Completed

Efficacy and Tolerance of Tocilizumab In Takayasu Arteritis (TOCITAKA)

TAKAYASU ARTERITIS

France
Hospices Civils de Lyon

Completed

TOCILIZUMAB IN FIBROUS DYSPLASIA OF BONE (TOCIDYS)

Fibrous Dysplasia of Bone

France
Bio-Thera Solutions

Active, not recruiting

A Randomized, Double-blind, Single-dose, Two-arm Parallel Study to Compare the Pharmacokinetics and Safety of BAT1806 Prefilled Subcutaneous Injection With RoActemra® in Healthy Chinese Male Subjects

Healthy Men

China
Academisch Medisch Centrum - Universiteit van Amsterdam...
Boston Scientific Corporation

Active, not recruiting

A PRospective, rAndomizEd Comparison of subcuTaneOous and tRansvenous ImplANtable Cardioverter Defibrillator Therapy (PRAETORIAN)

Ventricular Arrhythmias

United States, United Kingdom, Netherlands, Germany, Denmark, Czechia
Roxall Medicina España S.A

Completed

Subcutaneous Immunotherapy in Patients Sensitized to Dermatophagoides Pteronyssinus (DPT)

Allergic Rhinoconjunctivitis

Spain
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

China
Endo Pharmaceuticals

Completed

Histrelin Subcutaneous Implant in Children With Central Precocious Puberty

Central Precocious Puberty
Merz North America, Inc.
Ulthera, Inc

Completed

Study of the Cabochon System for Improvement in the Appearance of Cellulite

Gynoid Lipodystrophy

United States
Hasselt University
Jessa Hospital; Maastricht University

Completed

The Role of Atrial Natriuretic Peptide in the Lipolytic Process: Effect of Obesity and Exercise (BALO)

Obesity

Belgium
Shenzhen People's Hospital

Completed

Denosumab Effect on Bone Quality and Function After Lumbar Fusion Surgery

Osteopenia | Spine Fusion | Denosumab Allergy

China
Hoffmann-La Roche

Recruiting

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United Kingdom, Spain, Germany, Poland, South Africa, Netherlands
Rigshospitalet, Denmark

Completed

Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6

Healthy | Obesity

Denmark
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Patients With Active Polyarticular Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

Belgium, Canada, United States, United Kingdom, Argentina, Germany, Italy, Russian Federation, Spain, Mexico, Poland, Brazil, Australia, France, Peru
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Combination With Disease-Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Moderate to Severe Active Rheumatoid Arthritis With an Inadequate Response to DMARDs

Rheumatoid Arthritis

Italy
Hoffmann-La Roche

Completed

TORPEDO Study: A Study on Rapid Effect of Tocilizumab in Patients With Rheumatoid Arthritis With an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARDs) or Anti-TNF

Rheumatoid Arthritis

France
Kyowa Kirin Co., Ltd.

Completed

A Clinical Study of KRN321 in Adult Subjects With Myelodysplastic Syndrome

MDS

Japan, Korea, Republic of
AbbVie

Not yet recruiting

Study of ABBV-383 Assessing Adverse Events and Clinical Activity With Subcutaneous (SC) Injection in Adult Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma
University of Southern California
ConvaTec Inc.

Recruiting

Use of a Subcutaneous Catheter for Controlled Ovarian Stimulation

Infertility, Female

United States
China Medical University Hospital

Completed

Fu's Subcutaneous Needling Treatment for Knee Osteoarthritis

Knee Osteoarthritis

Taiwan
Centre Hospitalier Universitaire Dijon

Unknown

AGARIC Case Control Study (AGARIC)

First Recently-diagnosed Colorectal Cancer

France
United Therapeutics
CVie Therapeutics Co. Ltd.

Withdrawn

Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China
Medical University of Lodz

Unknown

Effect of Specific Immunotherapy to Dust Mites in Children With Asthma

Asthma

Poland
Affinivax, Inc.

Completed

Single Ascending Dose of ASP3772 Study in Japanese Healthy Male and Female Adults, and Single Ascending Dose Study of ASP3772 in Comparison With PPSV23 in Japanese Elderly Male and Female Subjects

Healthy Volunteers

Japan
Maimónides Biomedical Research Institute of Córdoba
Consejería de Salud y Familias - Junta de Andalucía; Red Andaluza de Ensayos...

Completed

Clinical Trial of Sarilumab in Adults With COVID-19 (SARICOR)

SARS-CoV 2 | SARS

Spain
Emory University
Thrasher Research Fund

Completed

Insulin Delivery Using Microneedles in Type 1 Diabetes

Type 1 Diabetes Mellitus

United States
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
German Cancer Research Center
University Hospital Tuebingen

Terminated

Bispecific PSMAxCD3 Antibody CC-1 in Patients With Squamous Cell Carcinoma of the Lung

Lung Cancer Squamous Cell

Germany
UCB Celltech
Parexel

Completed

A First-In-Human Study With a Single Dose UCB7665 in Healthy Volunteers

Healthy

United Kingdom
University of British Columbia
Medtronic

Active, not recruiting

Glucose Variability in Subclinical Hypertrophy

Diabetes Mellitus | Lipohypertrophy

Canada
AstraZeneca
Parexel

Completed

A Study to Assess Safety, Tolerability, PK and PD of AZD2373 in Healthy Male Participants of Sub-Saharan West African Ancestry

Healthy Volunteers

United States
AstraZeneca
Parexel

Completed

A First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD2373 After Single Dose Administration in Healthy Male Subjects of African Ancestry.

Healthy Volunteers

United States
GlaxoSmithKline

Completed

In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
King Edward Medical University

Completed

Irrigation and Suction Trial to Prevent SSI (I&S)

Diabete Mellitus | Surgical Site Infection | Abdominal Hysterectomy

Pakistan
University Hospital, Montpellier
University Hospital, Rouen; University Hospital, Lille; Nantes University Hospital and other collaborators

Terminated

Impact of Denosumab in the Prevention of Bone Loss in Non-menopausal Women With Anorexia Nervosa (DIBLAN)

Anorexia Nervosa

France
Columbia University
Incyte Corporation

Terminated

Itacitinib and Tocilizumab for Steroid Refractory Acute Graft Versus Host Disease (GVHD)

Graft Vs Host Disease | Steroid Refractory GVHD

United States
Hospital Universitario Dr. Jose E. Gonzalez

Completed

Tocilizumab for Cytokine Release Syndrome Prophylaxis in Haploidentical Transplantation

Cytokine Release Syndrome | Stem Cell Transplant Complications

Mexico
University Hospital, Brest

Completed

Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica (TENOR-IMMUNO)

Polymyalgia Rheumatica

France
Hoffmann-La Roche

Terminated

A Study of Tocilizumab (RoActemra/Actemra) in Patients With Ankylosing Spondylitis Who Have Had an Inadequate Response to Previous Tumor Necrosis Factor (TNF) Antagonist Therapy

Spondylitis, Ankylosing

Belgium, Czech Republic, France, Germany, Italy, Spain, United States, Canada, Poland, South Africa, United Kingdom, Australia, Denmark, Netherlands, Bulgaria, India, Lithuania, Brazil, Slovakia
Tel-Aviv Sourasky Medical Center
Amsterdam Rheumatology and Immunology Center

Unknown

Therapeutic Drug Monitoring of Tocilizumab in Rheumatoid Arthritis

Rheumatoid Arthritis | Tocilizumab

Israel
Fundació Institut de Recerca de l'Hospital de la...

Completed

Immunoregulatory Mechanisms of Treg Cells Induced by Tocilizumab

Arthritis,Rheumatoid

Spain
University of Michigan Rogel Cancer Center

Withdrawn

Study of Tocilizumab in Patients With Hepatocellular Carcinoma (HCC) Undergoing Transarterial Chemoembolization (TACE)

Hepatocellular Carcinoma

United States
University of Texas Southwestern Medical Center

Completed

The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study (SIMPLE)

Diabetes Mellitus, Type 2 | Diabetes

United States
Weill Medical College of Cornell University

Terminated

Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)

Glucocorticosteroid Refractory Acute GVHD

United States
Mayo Clinic

Terminated

Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

Heart Failure

United States
United Allergy Services

Unknown

Corn Occupational Rhinitis SCIT Efficacy Study

Rhinitis
Hoffmann-La Roche

Completed

A Time to Cardiovascular Event Analysis Comparing Tocilizumab to Other Biologics in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

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