Search clinical trials for: Ticagrelor

Total 449 results

Liverpool University Hospitals NHS Foundation Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Countess of Chester... and other collaborators

Completed

The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome (ROBOT-ACS)

Bleeding | Acute Coronary Syndrome | Ticagrelor | Clopidogrel | Novel Anti-platelets

United Kingdom
Yonsei University

Not yet recruiting

Dual Antiplatelet Therapy in Patients With Clopidogrel Resistance Following Off-Pump Coronary Artery Bypass

Multi Vessel Coronary Artery Disease

Korea, Republic of
University of Florida
AstraZeneca

Completed

Low Maintenance Dose Ticagrelor Versus Clopidogrel in Diabetes Patients Undergoing PCI (OPTIMUS-6)

Coronary Artery Disease | Diabetes Mellitus, Type 2

United States
Medical University of Warsaw
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Antiplatelet Therapy Effect on Extracellular Vesicles in Acute Myocardial Infarction (AFFECT EV)

Myocardial Infarction

Netherlands, Poland
AORTICA Group

Completed

Prasugrel vs. Ticagrelor on Myocardial Injury in STEMI (COMPARE)

ST Elevation Myocardial Infarction

Spain
Federal University of São Paulo

Completed

Sampling P2Y12 Receptor Inhibition With Prasugrel and Ticagrelor in Patients Submitted to Thrombolysis (SAMPA)

Acute Coronary Syndrome | Platelet Function

Brazil
Unity Health Toronto
Prairie Vascular Research Inc.

Completed

Ticagrelor for PCI Post Thrombolysis (SETFAST)

Acute Myocardial Infarction

Canada
Michael Wolzt, Prof. MD

Completed

The Effect of Ticagrelor or Clopidogrel on Endothelial Function During Acute and Chronic Treatment

Ischemia

Austria
Deutsches Herzzentrum Muenchen

Unknown

Intracoronary Stenting and Antithrombotic Regimen: ADjusting Antiplatelet Treatment in PatienTs Based on Platelet Function Testing (ISAR ADAPT PF)

Coronary Heart Disease

Germany, Hungary
University of Patras

Completed

Ticagrelor in Comparison to Prasugrel for Early Inhibition of Platelet Reactivity in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)

Platelet Reactivity

Greece
Second Affiliated Hospital, School of Medicine,...

Completed

Ticagrelor Versus Clopidogrel for CMD in Patients With AMI: A Retrospective Study Based on the Angio-IMR

Coronary Heart Disease

China
University of Arkansas
American Society of Nephrology

Completed

Chronic Kidney Disease (CKD) Platelet Study

Chronic Kidney Diseases | Stroke, Ischemic | Heart Attack

United States
University Hospital, Bordeaux

Completed

Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI) (TICTAVI)

Aortic Valve Stenosis

France
University of Athens

Completed

A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI (PTOLEMAIOS)

Aortic Valve Stenosis

Greece
AstraZeneca
Iqvia Pty Ltd

Withdrawn

Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease. (HESTIA5)

Sickle Cell Disease
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Drug Drug Interaction

United States, Sweden
University of Maryland, Baltimore

Completed

CES1 Crossover Trial of Clopidogrel and Ticagrelor

Myocardial Infarction | Thrombosis | Platelet Dysfunction

United States
Universiti Sains Malaysia

Completed

Impact of CYP2C19 Genotype-guided Clopidogrel and Ticagrelor Treatment on Platelet Function Test and Metabolomics Profile

Coronary Artery Disease (CAD)

Malaysia
Spanish Society of Cardiology
AstraZeneca

Unknown

Comparison of TIcagrelor and Clopidogrel in Patients With Coronary Artery diseaSe and Type 2 Diabetes Mellitus (TICS-DM) (TICS-DM)

Coronary Artery Disease | Diabetes Mellitus. Type 2

Spain
Jinan Central Hospital

Unknown

Comparison of Ticagrelor And Clopidogrel on Inflammatory Biomarkers And Vascular Endothelial Function (TIGERCAVE)

ST-Segment Elevation Myocardial Infarction

China
First Hospital of China Medical University
AstraZeneca

Unknown

Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI

Myocardial Infarction | No-Reflow Phenomenon

China
University of Patras

Completed

Ticagrelor Versus Prasugrel in Acute Coronary Syndromes After Percutaneous Coronary Intervention

Coronary Artery Disease | Acute Coronary Syndrome

Greece
Assiut University

Unknown

Effect of Upstream Treatment With High Intensity Statin on the Outcomes of STMI Patients Treated With PPCI

ST Elevation Myocardial Infarction
Beijing Tiantan Hospital
Beijing Municipal Science & Technology Commission

Completed

Platelet Reactivity in Acute Non-disabling Cerebrovascular Events (PRINCE)

Stroke | Ischemic Attack, Transient

China
The University of Hong Kong

Completed

Ticagrelor Monotherapy Compared to Aspirin Monotherapy in Patients With History of ACS (FMD_ACS)

Acute Coronary Syndrome

China
AstraZeneca

Completed

A Study of the Onset and Offset of Antiplatelet Effects Comparing Ticagrelor, Clopidogrel, and Placebo With Aspirin

Coronary Artery Disease

United States, United Kingdom
Assistance Publique - Hôpitaux de Paris
AstraZeneca; Action Research Group

Completed

Assessment of Loading With the P2Y12 Inhibitor Ticagrelor or Clopidogrel to Halt Ischemic Events in Patients Undergoing Elective Coronary Stenting (ALPHEUS)

Myocardial Infarction | Myocardial Ischemia | Cardiovascular Diseases | Coronary Artery Disease | Stent Thrombosis

France
Campus Bio-Medico University

Completed

Clopidogrel Versus Ticagrelor in Type-2 Diabetes

Coronary Artery Disease | Diabetes Mellitus
Thorax Centrum Twente

Completed

Change of Dual Antiplatelet Therapy in Patients With Acute Coronary Syndrome (CHANGE DAPT)

Acute Coronary Syndrome | Percutaneous Coronary Intervention | Drug-Eluting Stents

Netherlands
University of Patras

Completed

Differential Effect of Ticagrelor Versus Prasugrel Maintenance Dose on Endothelial Function of Peripheral Vessels in Patients With Coronary Artery Disease

Coronary Artery Disease | Endothelial Function

Greece
University Hospital of Limerick

Completed

Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI

Myocardial Ischemia | Coronary Artery Disease | Endothelial Dysfunction

Ireland
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0200 Carboplatin With or Without Doxil in Patients With Recurrent Ovarian Cancer

Ovarian Cancer | Peritoneal Cavity Cancer

United States
General Hospital of Chinese Armed Police Forces

Unknown

Efficacy and Safety Study of Ticagrelor

Acute Coronary Syndrome

China
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); Spartan Bioscience Inc.; Applied...

Completed

Tailored Antiplatelet Therapy Following PCI (TAILOR-PCI)

Coronary Artery Disease | Acute Coronary Syndrome | Stenosis

United States, Korea, Republic of, Canada, Mexico
University of Florida

Completed

Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery Disease (SWAP-4)

Coronary Artery Disease

United States
Baylor College of Medicine

Withdrawn

The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and Inflammation

Atherosclerosis

United States
Medical Center of South Arkansas

Withdrawn

Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis (TACAT)

Acute Coronary Syndrome | Acute ST Segment Elevation Myocardial Infarction

United States
Yongjian Wu

Unknown

Evaluation of Antiplatelet Effects and Safety of Intraoperative Administration of Ticagrelor Versus Clopidogrel

Coronary Disease

China
Catholic University of the Sacred Heart

Terminated

Study of Effects of Ticagrelor on Microparticles and Micro-RNA in NSTE-ACS (TIGER-M)

Non ST Segment Elevation Acute Coronary Syndrome

Italy
Kyunghee University Medical Center

Unknown

Genotype and Platelet Reactivity in Patients on Hemodialysis

Chronic Kidney Disease

Korea, Republic of
Mina Wageh Mohareb
Al-Azhar University

Recruiting

Individualized and Combined Effects of Diabetes and Smoking on the Antiplatelet Activity of Ticagrelor in Acute Myocardial Infarction Patients Undergoing Primary PCI

Individualized and Combined Effects of Smoking and Diabetes on the Antiplatelet Activity in Patients Undergoing Primary Percutaneous Coronary Intervention

Egypt
Hellenic Society of Interventional Cardiology

Completed

Ticagrelor in Remote Ischemic Preconditioning Study (TRIP)

Periprocedural Myocardial Infarction

Greece
AstraZeneca

Completed

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease (EUCLID)

Peripheral Artery Disease

United States, Canada, France, Italy, Netherlands, Spain, United Kingdom, Czechia, Thailand, Russian Federation, Vietnam, Germany, Korea, Republic of, Brazil, Hungary, Mexico, Philippines, Turkey, China, Slovakia, Japan, Bulgaria, R... and more
Lawson Health Research Institute

Completed

Effect of Ticagrelor on Endothelial Function

Coronary Artery Disease | Endothelial Function

Canada
Careggi Hospital

Completed

Rapid Activity of Platelet Inhibitor Drugs Study (RAPID)

ST-segment Elevation Myocardial Infarction

Italy
University of Patras

Completed

Τicagrelor Versus Prasugrel in Diabetic Patients: a Pharmacodynamic Study

Coronary Artery Disease | Acute Coronary Syndrome

Greece
AstraZeneca

Completed

A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome (PLATO)

Acute Coronary Syndrome

Sweden, United States, Bulgaria, Czech Republic, France, Italy, Korea, Republic of, Poland, Russian Federation, South Africa, Turkey, United Kingdom, Germany, Philippines, China, Hungary, Romania, Denmark, Netherlands, Norway, C... and more
General Hospital of Ningxia Medical University

Not yet recruiting

Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic Patients

Adverse Effect
The Cleveland Clinic

Terminated

Establishing the Microcirculatory Effects of Ticagrelor on Tissue Perfusion in Critical Limb Ischemia

Peripheral Arterial Disease

United States
Chiang Mai University

Unknown

Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving DAPT Undergoing Dental Procedure.

Antiplatelet Agents | Dental Diseases | Antiplatelet Drugs

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