Search clinical trials for: tocilizumab and IV steroids combination

Total 16788 results

Centre Hospitalier National d'Ophtalmologie des...
Roche Chugai

Recruiting

Efficacy of Tocilizumab for the Treatment of Acute AION Related to GCA (TOCIAION)

Giant Cell Arteritis | Optic Ischaemic Neuropathy

France
Jarmo Oksi

Completed

COVID-19: Salvage TOcilizumab as a Rescue Measure (COVIDSTORM)

Covid19

Finland
Hoffmann-La Roche

Completed

A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

France, Germany, Italy, Spain, United Kingdom, Hong Kong, United States, Colombia, Brazil, Canada, New Zealand, South Africa, Philippines, Russian Federation, Thailand, Singapore, Bulgaria, Mexico, Australia, Lithuania, Poland, Ar... and more
Marius Henriksen

Terminated

Anti-il6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure (TOCIVID)

Corona Virus Disease

Denmark
University of Ulm

Completed

Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application (CasiTocCOVID)

COVID-19 | Critically Ill | Outcome, Fatal | Interleukin 6 | Tocilizumab

Germany
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

TOward the Lowest Effective DOse of Abatacept or Tocilizumab (TOLEDO)

Rheumatoid Arthritis

France
M Abdur Rahim Medical College and Hospital
First Affiliated Hospital Xi'an Jiaotong University; Cox's Bazar 250 Bed District... and other collaborators

Completed

Efficacy and Safety of Remdesivir and Tociluzumab for the Management of Severe COVID-19: A Randomized Controlled Trial

Covid19 | Covid-19 ARDS

Bangladesh
Almirall, S.A.
proDERM GmbH

Completed

Efficacy and Tolerability of LAS41004 Formulations in a Non-occlusive Psoriasis Plaque Test (PPT4)

Psoriasis

Germany
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma

United States, Israel, Italy, Spain, United Kingdom
UCB Pharma

Completed

Efficacy and Safety of CDP6038 in Patients With Rheumatoid Arthritis With an Unsuccessful Response to Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

Rheumatoid Arthritis

United States, Belgium, United Kingdom
Hoffmann-La Roche

Active, not recruiting

Trial of Mosunetuzumab (BTCT4465A) as Consolidation Therapy in Participants With Diffuse Large B-Cell Lymphoma Following First-Line Immunochemotherapy and as Monotherapy or in Combination With Polatuzumab Vedotin in Elderly/Unfit Participants With Previously Untreated Diffuse Large B-Cell Lymphoma

Diffuse Large B-cell Lymphoma

United States, Israel, Spain, Korea, Republic of, Poland, Taiwan
Hoffmann-La Roche

Completed

A Long-term Extension Study of Tocilizumab (Myeloma Receptor Antibody [MRA]) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

France, Israel, Italy, Hong Kong, Switzerland, Canada, Germany, Mexico, Austria, Thailand, Singapore, Hungary, Bulgaria, Australia, Argentina, Slovakia, Brazil
National Institute of Allergy and Infectious Diseases...

Recruiting

Tocilizumab in Lung Transplantation (ALL IN LUNG)

Lung Transplant

United States, Canada
University Hospital, Toulouse

Recruiting

Evaluation of the Safety of Use of Anti-IL6 Receptor Antibodies to Reduce Allo-sensitization Post Allograft Nephrectomy (RAIPONS)

Kidney Transplantation | Graft Failure

France
Flavio Vincenti

Completed

Tocilizumab for Renal Graft Inflammation

Late Complication From Kidney Transplant

United States
Tel-Aviv Sourasky Medical Center
Rambam Health Care Campus; Assaf-Harofeh Medical Center; Bnai Zion Medical Center

Unknown

Efficacy and Safety of Tocilizumab in Adult's Still Disease

Adult's Still Disease

Israel
Peking University First Hospital

Unknown

Favipiravir Combined With Tocilizumab in the Treatment of Corona Virus Disease 2019

COVID-19

China
University Hospital, Brest
Roche Chugai

Completed

Safety and Efficacy of tocilizuMAb Versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence SEMAPHORE

Polymyalgia Rheumatica

France
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen (BCMA)-Exposed Participants With Relapsed/Refractory Multiple Myeloma (CAMMA 2)

Multiple Myeloma

United States, Italy, Spain, Australia, Belgium, Israel, Germany, France
Hadassah Medical Organization
Sheba Medical Center; Wolfson Medical Center

Unknown

The Use of Tocilizumab in the Management of Patients Who Have Severe COVID-19 With Suspected Pulmonary Hyperinflammation

Covid19 Pneumonia

Israel
Hospital for Special Surgery, New York
Genentech, Inc.

Completed

Study of Tocilizumab to Treat Polymyalgia Rheumatica

Polymyalgia Rheumatica (PMR)

United States
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With Polatuzumab Vedotin in B-Cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

United States, Canada, Belgium, Spain, United Kingdom
Hoffmann-La Roche

Active, not recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma

Follicular Lymphoma

United Kingdom, United States, China, France, Spain
Tessa Therapeutics

Completed

A Phase III Trial Evaluating Chemotherapy and Immunotherapy for Advanced Nasopharyngeal Carcinoma (NPC) Patients (VANCE)

Nasopharyngeal Carcinoma

United States, Taiwan, Malaysia, Singapore, Thailand
Mycenax Biotech Inc.

Completed

Phase I, Pharmacokinetic, Safety and Tolerability Study in Healthy Volunteers

Pharmacokinetics

Australia
Insel Gruppe AG, University Hospital Bern

Not yet recruiting

PRONTO Trial (PRophylactic Versus ON-demand Use of TOcilizumab) (PRONTO)

Lymphoma | Leukemia | Myeloma

Switzerland
The First Affiliated Hospital of Soochow University

Recruiting

Safety and ASCT-related Symptom Burden Optimization of Tocilizumab in ASCT Following HD Melphalan Conditioning for Multiple Myeloma Patients

Multiple Myeloma

China
Hoffmann-La Roche

Completed

A Study of Tocilizumab (RoActemra/Actemra) Versus Adalimumab in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Belgium, Germany, Spain, Sweden, United Kingdom, United States, Brazil, Greece, Portugal, Turkey, Finland, Switzerland, Australia, Mexico, Czech Republic
Fu-Dong Shi

Completed

A Longitudinal Study of ACTEMRA® (Tocilizumab) as Monotherapy in Highly Active NMOSD

Neuromyelitis Optica | Neuromyelitis Optica Spectrum Disorders | Devic's Disease

China
Takeda

Recruiting

Specified Drug-Use Survey on Vedolizumab for IV Infusion 300 mg [Crohn's Disease]

Crohn's Disease

Japan
SCRI Development Innovations, LLC
Janssen Research & Development, LLC

Recruiting

Outpatient Administration of Teclistamab for Multiple Myeloma

Multiple Myeloma

United States
Affiliated Hospital of Nantong University

Active, not recruiting

Combined Anti-IL6R and Anticoagulation Therapy in Advanced NPC Patients

Nasopharyngeal Carcinoma

China
Hoffmann-La Roche

Completed

A Study of Decreased Dose Frequency in Participants With Systemic Juvenile Arthritis Who Experience Laboratory Abnormalities During Treatment With RoActemra/Actemra (Tocilizumab)

Juvenile Idiopathic Arthritis

Canada, Mexico, United States, Argentina, Germany, Israel, Italy, Russian Federation, Spain, United Kingdom
Hoffmann-La Roche

Completed

Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Participants With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Non-Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) and/or Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Rheumatoid Arthritis

India
Hoffmann-La Roche

Completed

EMBRACE-SC: Observational Study of Subcutaneous (SC) Tocilizumab Alone or in Combination With Conventional Disease-Modifying Antirheumatic Drugs (cDMARDs) in Rheumatoid Arthritis

Rheumatoid Arthritis

Greece
MediMergent, LLC

Terminated

Real World Evaluation of the Effectiveness of AZD7442 for Prevention of SARS-CoV-2

SARS-CoV-2 Infection

United States
University of Southern Denmark
Odense University Hospital; Sygehus Lillebaelt; Odense Patient Data Explorative... and other collaborators

Terminated

Interleukin-6 Inhibitors and Drug-drug Interactions in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid | Interaction

Denmark
Tufts Medical Center
Hoffmann-La Roche

Terminated

Single Patient Use of Tocilizumab in Systemic Onset Juvenile Idiopathic Arthritis

Arthritis, Juvenile Rheumatoid | Still's Disease, Juvenile Onset

United States
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA22763 and NA25220 of Subcutaneous RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Herlev Hospital
Bristol-Myers Squibb

Completed

Checkpoint Inhibitor Induced Colitis and Arthritis -Immunomodulation With IL-6 Blockade and Exploration of Disease Mechanisms (COLAR)

Arthritis | Solid Tumor | Colitis

Denmark
Kathy Miller
Genentech, Inc.

Recruiting

Phase II Trial of Carboplatin +/- Tocilizumab for Metastatic Triple Negative and ER-low Breast Cancers

Metastatic Breast Cancer | Triple Negative Breast Cancer | Estrogen-receptor-low Breast Cancer

United States
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Participants With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Non-Biological Disease-modifying Anti-rheumatic Drugs (DMARDs)

Rheumatoid Arthritis

Montenegro
Hoffmann-La Roche

Completed

A Study Assessing the Safety and Efficacy of Subcutaneous RoActemra/Actemra Alone or in Combination With Non-biologic Antirheumatics in Rhuematoid Arthritis Patients in Latin America With Inadequate Response to Non-biologic Antirheumatic Drugs.

Rheumatoid Arthritis

Brazil, Colombia, Argentina, Dominican Republic, Mexico, Venezuela
Hoffmann-La Roche

Completed

A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases

Carcinoma, Hepatocellular | Liver Metastases | Biliary Tract Cancer | Secondary Liver Cancer

Korea, Republic of, Denmark, Spain, Taiwan, United States, Hong Kong
New York State Psychiatric Institute
Stanley Medical Research Institute

Completed

Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) Plus DMARDs in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

South Africa
Genentech, Inc.

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

Relapsed or Refractory Multiple Myeloma

Korea, Republic of, Australia, Israel
Valio Ltd
University of Helsinki

Completed

Bioactive Milk Peptides and Blood Pressure

Stage 1 Hypertension

Finland
University Health Network, Toronto
Janssen Inc.

Not yet recruiting

Plan Development for Giving Teclistamab in the Outpatient Setting

Multiple Myeloma | Relapsed Cancer | Refractory Cancer
Hoffmann-La Roche

Terminated

A Study to Evaluate Safety, Pharmacokinetics, and Preliminary Anti-tumor Activity of RO7444973 in Participants With Unresectable and/or Metastatic MAGE-A4-positive Solid Tumors

Solid Tumors

Belgium, United States, Australia, Denmark, Spain, United Kingdom

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