Clinical Trials Sponsored by Cardiff Oncology

Total 5124 results

Cardiff Oncology

Completed

Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

United States
Cardiff Oncology

Completed

Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Cardiff Oncology

Active, not recruiting

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab Versus FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer in Participants With a Kirsten Rat Sarcoma Virus Gene (KRAS) or Neuroblastoma-RAS (NRAS) Mutation

Metastatic Colorectal Cancer | Colorectal Cancer

United States
Cardiff Oncology

Completed

Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a Kras Mutation

Metastatic Colorectal Cancer | KRAS Gene Mutation

United States
Cardiff Oncology

No longer available

Expanded Access of Onvansertib With FOLFIRI and Bevacizumab for the Second-Line Treatment of Participants With KRAS-Mutated Metastatic Colorectal Cancer

Metastatic Colorectal Cancer | KRAS Gene Mutation
Cardiff Oncology

Active, not recruiting

Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma

United States
Cardiff Oncology
Pfizer

Recruiting

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

Metastatic Colorectal Cancer | CRC | KRAS/NRAS Mutation

United States
Memorial Sloan Kettering Cancer Center
Cardiff Oncology

Completed

Detection of Oncogenic Tumor Mutations in the Urine and Blood of Lung and Colorectal Cancer Patients

Colorectal Cancer | Lung Cancer

United States
Cardiff Metropolitan University
Cardiff University

Recruiting

The Effects of High-intensity and Moderate-intensity Exercise on Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Exercise | Cerebrovascular Circulation

United Kingdom
Antonio Giordano, MD
Cardiff Oncology

Recruiting

Onvansertib + Paclitaxel In TNBC

Breast Cancer | Metastatic Breast Cancer | Inflammatory Breast Cancer | Invasive Breast Cancer | Locally Advanced Breast Cancer | Unresectable Breast Carcinoma | HER2-negative Breast Cancer | Triple Negative Breast Cancer (TNBC) | Hormone Receptor Negative Breast Carcinoma | Hormone Receptor/Growth Factor...

United States
Cardiff University

Completed

Platelet Enzymatically Oxidized Phospholipids (eoxPL) Characterisation in a Healthy Cohort on and Off Aspirin

Platelet Dysfunction Due to Aspirin

United Kingdom
Cardiff University

Completed

Diagnostic Investigation and Prediction of Shock (DiPS)

Shock

United Kingdom
Cardiff University

Completed

Gemcitabine Hydrochloride, Cisplatin, and Sunitinib Malate as First-Line Therapy in Treating Patients With Locally Advanced And/or Metastatic Transitional Cell Carcinoma of the Urothelium (SUCCINCT)

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

United Kingdom
Cardiff University

Completed

Comparison of Medical Therapies in Marfan Syndrome.

Marfan Syndrome

United Kingdom
Cardiff University

Not yet recruiting

Evaluating an ACT Self-help Book for University Students

Well-Being, Psychological

United Kingdom
Cardiff University

Not yet recruiting

Study in Adult Ph-positive ALL (EWALL-Ph-03)

Acute Lymphoblastic Leukemia, Adult
Cardiff University

Recruiting

Phase 1b/II Trial of Pembrolizumab Plus IMRT in Stage III/IV Carcinoma of Anus (CORINTH)

Anal Cancer Stage III A | Anal Cancer Stage III B

United Kingdom, Norway
Cardiff University

Completed

Enhanced Epidermal Antigen Specific Immunotherapy Trial -1 (EE-ASI-1)

Type 1 Diabetes

United Kingdom
Cardiff University

Completed

Life-Style Exercise and Activity Package for People Living With Progressive MS (LEAP-MS)

Multiple Sclerosis

United Kingdom
Cardiff University

Completed

Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen Test

Healthy | Hypopituitarism | Adrenal Insufficiency

United Kingdom
Cardiff University

Completed

Carboplatin and Gemcitabine Hydrochloride With or Without Vandetanib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urinary Tract Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Ureter Cancer | Urethral Cancer

United Kingdom
Cardiff University

Completed

Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

United Kingdom
Cardiff University
GlaxoSmithKline; Cardiff Metropolitan University

Completed

Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Cardiff University

Completed

Study to Investigate the Effects of Hot Drinks on Nasal Airway Resistance and Symptoms of Common Cold

Common Cold/Flu

United Kingdom
Cardiff University

Withdrawn

Carboplatin With or Without ZD4054 in Patients With Metastatic Breast Cancer (PLANET)

Metastatic Breast Cancer

United Kingdom
Cardiff University

Completed

Real-time fMRI Neurofeedback for Treatment of Parkinson's Disease

Parkinson's Disease

United Kingdom
Cardiff University

Completed

Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium With or Without Zibotentan in Treating Patients With Metastatic Colorectal Cancer (FOLFERA)

Colorectal Cancer

United Kingdom
Cardiff and Vale University Health Board
Cardiff University

Completed

Magnetic Resonance Imaging and Neuro-Psychological Testing In Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Cardiff University
Cardiff and Vale University Health Board

Unknown

Molecular Imaging of Pituitary Adenomas (MIMOPA)

Pituitary Adenoma

United Kingdom
Cardiff and Vale University Health Board
Cardiff University

Unknown

Role of Polymorphisms in the Dectin-1 Gene in Determining the Risk of Candida Colonization and Infection in Critically Ill Patients (Dectin-1)

Critically Ill

United Kingdom
Cardiff and Vale University Health Board
Cardiff University

Recruiting

Ventilator Aspiration With PneuX (PneuX vs Standard Care Feasibility RCT) (VAP-X)

Infections | Ventilator Associated Pneumonia | Ventilator Lung | Aspiration

United Kingdom
Cardiff University
Cardiff and Vale University Health Board

Recruiting

mSEP: Testing of Physiological and Immune-metabolic Blood Markers for Maternal Sepsis

Sepsis | SIRS | Pregnancy; Infection | Maternal Sepsis During Labor | Maternal Sepsis

United Kingdom
Cardiff and Vale University Health Board
Cardiff University

Recruiting

nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis (nSeP)

Sepsis

United Kingdom
Cardiff and Vale University Health Board
Cardiff University

Completed

Estimating Insertion Length of Umbilical Catheters in Newborn Infants

Infant, Newborn, Diseases

United Kingdom
Cardiff University
Cardiff and Vale University Health Board

Recruiting

Blood Markers for Identifying & Investigating Infection With COVID19 & Sepsis in Children. (pSeP)

Sepsis | Covid19

United Kingdom
Cardiff University
Cardiff and Vale University Health Board

Completed

uSing Wearable TEchnology to Predict Perioperative High-riSk Patient Outcomes (STEPS)

Perioperative Care

United Kingdom
Cardiff University
Novartis

Unknown

A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis (TRON)

Tuberous Sclerosis

United Kingdom
Taofeek Owonikoko
National Cancer Institute (NCI); Cardiff Oncology

Active, not recruiting

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

Small Cell Lung Carcinoma | Small-cell Lung Cancer

United States
Cardiff and Vale University Health Board
Cardiff Metropolitan University

Completed

Development of Volatile Organic Compounds (VOC) Analysis as a Potential Diagnostic for Infected and Non-Healing Wounds (AROMA)

Non-healing Wound | Pilonidal Abscess

United Kingdom
Cardiff and Vale University Health Board
Abbott; Cardiff Metropolitan University

Completed

Cardiac Resynchronisation Therapy Versus Rate-responsive Pacing in Heart Failure With Preserved Ejection Fraction (PREFECTUS)

Diastolic Heart Failure

United Kingdom
Cardiff University
European Commission

Completed

Neurofeedback & Alcohol Dependence

Alcohol Dependence

United Kingdom
Swansea University
Cardiff University

Completed

Wales Electronic Cohort for Children (WECC)

Premature Birth | Low Birth Weight | Childhood Obesity | Macrosomia | Poverty

United Kingdom
Lisette Nixon

Completed

Feasibility of Reduction in Right Sided Bowel Cancer Through Contrast Enhanced Colonoscopy (CONSCOP)

Colorectal Cancer

United Kingdom
Cardiff University
Diabetes UK

Terminated

Trial of Motivational Interviewing in Adolescents With Diabetes

Diabetes Mellitus

United Kingdom
Lisette Nixon

Completed

Gemcitabine, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by Surgery (SCALOP)

Pancreatic Cancer

United Kingdom
Cardiff University
European Commission

Completed

Optimisation of Functional MRI-based Neurofeedback for Alcohol Use Disorders

Alcohol Abuse

United Kingdom
Cardiff University
Nottingham Trent University

Recruiting

Self-help Booklets for Depression in Adults With Pulmonary Hypertension.

Depression | Pulmonary Hypertension

United Kingdom
Cardiff University
CHDI Foundation, Inc.

Unknown

PHysical Activity and Exercise Outcomes in Huntington's Disease (PACE-HD)

Huntington Disease

Spain, Germany, United States
Cardiff University
Cancer Research UK

Completed

Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery (COPERNICUS)

Colorectal Cancer

United Kingdom
Cardiff University
University of Canterbury

Recruiting

Mindful Parenting - A Single Case Experimental Design Study

Cleft Lip and Palate | Parenting | Neurofibromatoses | Skin Condition | Alopecia | Craniofacial | Limb Difference

United Kingdom

Clinical Trials Sponsored by Cardiff Oncology

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