Clinical Trials Sponsored by MICALIS Institute

Total 74333 results

University Hospital, Montpellier
CBS; MICALIS

Recruiting

Synthetic Metabolic and Genetic Networks for Medical Diagnosics (SynBioDiag)

Cancer | Prostate

France
Assistance Publique - Hôpitaux de Paris
INRAe - Micalis Institute - Jouy en Josas

Not yet recruiting

EDN and Eosinophilic Esophagitis (OesEDN)

Eosinophilic Esophagitis

France
Nivalis Therapeutics, Inc.

Completed

MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetic Effects of N91115 in Healthy Subjects (SNO2)

Healthy

United States
Michalis Karamouzis

Recruiting

The Impact of Thromboprophylaxis on Progression Free Survival of Patients With Advanced Pancreatic Cancer (imPaCT-PRO)

Pancreatic Cancer | Thromboembolism

Greece
Firalis SA

Not yet recruiting

Validation of the Stability of Diagnostic Biomarkers on Healthy Volunteers

Healthy

France
Firalis SA

Active, not recruiting

HeartLinc, a Study With AMI Patients Undergoing PCI (HeartLinc)

AMI Patients

France, Korea, Republic of
Nivalis Therapeutics, Inc.

Completed

Study of N91115 in Patients With Cystic Fibrosis Homozygous F508del-CFTR Mutation (SNO4)

Cystic Fibrosis

United States
Nivalis Therapeutics, Inc.

Completed

Safety and Pharmacokinetic Study of N6022 in Subjects With Cystic Fibrosis Homozygous for the F508del-CFTR Mutation (SNO-1)

Cystic Fibrosis

United States
Michalis Efstathiou

Unknown

Comparison of Neural Mobilization Techniques to Standard Care Treatment in Patients With Lumbar Radiculitis

Radiculitis
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin; MICALIS Institute

Recruiting

Use of Crohn's Disease Exclusion Diet on Top of Standard Therapy Versus Standard Therapy Alone in Unstable Pediatric Crohn's Disease Patients. (ASCENSION)

Crohn's Disease

France
Nivalis Therapeutics, Inc.

Completed

MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Cavosonstat (N91115) in Healthy Subjects (SNO-9) ((SNO-9))

Cystic Fibrosis

United States
Nivalis Therapeutics, Inc.

Unknown

Study of Cavosonstat (N91115) in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor (SNO-7)

Cystic Fibrosis

United States
Nivalis Therapeutics, Inc.

Completed

PK Study of N91115 in Cystic Fibrosis Patients (SNO3)

Cystic Fibrosis

United States
Nivalis Therapeutics, Inc.

Completed

A Safety Study Evaluating N6022 in Multiple-Ascending Doses in Healthy Subjects

Healthy

United States
Nivalis Therapeutics, Inc.

Completed

Study to Evaluate the Bronchoprotective Effects of a Single Dose of N6022 in Patients With Mild Asthma

Asthma

United States
Nivalis Therapeutics, Inc.

Completed

Safety and Tolerability Study of N6022 in Healthy Subjects

Healthy

United States
Firalis SA
Istanbul University

Recruiting

Validation of a Rapid, Non-invasive Point-of-care IVD Test for Diagnosis of SARS-COV-2 (COVID-19) Infection (EasyCov)

SARS-CoV

Turkey
Nivalis Therapeutics, Inc.
Davita Clinical Research

Completed

A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects

Drug Interaction Potentiation

United States
Firalis SA
Herz-Zentrums Bad Krozingen

Completed

Prospective Study With AMI Patients Undergoing PCI (CardioSAVE)

Heart Failure

Germany
Nivalis Therapeutics, Inc.
Medidata Solutions

Completed

Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation (SNO-6)

Cystic Fibrosis

United States
University Hospital, Clermont-Ferrand
Unite de Nutrition Humaine UMR 1019- INRAE; Unite MetaGenoPolis INRAE; France...

Completed

Sampling of Human Microbiota in Order to Test, on a Mouse Model, Individualized Intervention Strategies During Aging (FRAGIBIOTE)

Healthy Volunteers | Frail Volunteers

France
Mical Paul
European Commission

Completed

Multicenter Open-label Randomized Controlled Trial (RCT) to Compare Colistin Alone Versus Colistin Plus Meropenem

Gram-Negative Bacterial Infections

Israel, Greece, Italy
University of Messina
Natasha Irrera; Gianluca Di Bella; Antonio Micari; Roberto Licordari

Recruiting

Modulation of Fibrosis-inducing Pathways in Acute Myocardial Infarction (BETA-MI)

Myocardial Infarction | Myocardial Fibrosis | Myocardial Remodeling, Ventricular

Italy
Karolinska Institutet
The Swedish Institute

Recruiting

MIDWIZE - Strengthening Midwives

Midwifery

Uganda
Institute of Rheumatology, Prague
Karolinska Institutet

Completed

Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM (Prometheus)

Dermatomyositis | Polymyositis

Czech Republic
Karolinska Institutet
Children's National Research Institute

Completed

Resistance Exercise Reduces the Expression of Inflammation and Fibrosis Associated Genes in Autoimmune Myositis Patients

Exercise | Myositis

Sweden
Jules Bordet Institute
AstraZeneca; Institut Curie

Active, not recruiting

Neo-adjuvant Chemotherapy Combined With Stereotactic Body Radiotherapy to the Primary Tumour +/- Durvalumab, +/- Oleclumab in Luminal B Breast Cancer: (Neo-CheckRay)

Luminal B

France, Belgium
The Netherlands Cancer Institute
Institut Curie

Terminated

Pre- Versus Postoperative Accelerated Partial Breast Irradiation (PAPBI-2)

Breast Cancer | Neoplasms, Breast | Cancer of the Breast

France, Netherlands, Portugal, Spain
Institut Bergonié
National Cancer Institute, France

Completed

Validation of a Screening Tool in Geriatric Oncology (ONCODAGE)

Lymphoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer

France
Institut Bergonié

Completed

Effect of Advertisements on Treatment Compliance in Women With Breast Cancer

Breast Cancer
Institut Curie

Completed

Sunitinib as Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Transitional Cell Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

France
Institut Bergonié

Completed

MRI in Evaluating Early Response to Chemotherapy in Women Receiving Chemotherapy for Infiltrating Breast Cancer

Breast Cancer

France
Institut Bergonié

Completed

Psychological and Social Factors That May Increase the Risk of Developing Chronic Pain After Surgery in Women With Breast Cancer

Pain | Breast Cancer | Psychosocial Effects of Cancer and Its Treatment
Institut Curie

Unknown

Study of Tumor and Blood Samples From Women With Breast Cancer

Breast Cancer

France
Institut Bergonié

Unknown

Efavirenz as Second-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer

France
Institut Curie

Unknown

Radiation Therapy With or Without Temozolomide in Treating Women With Brain Metastases and Breast Cancer

Breast Cancer | Metastatic Cancer

France
Institut Curie
National Cancer Institute, France

Completed

ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer Surgery (ER-One)

Breast Surgery

France
Institut Bergonié
National Cancer Institute, France

Completed

A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma (RADIOSARP)

Soft-tissue Sarcoma

France
Institut Curie

Completed

Blood Levels of Tumor Cells in Predicting Response in Patients Receiving First-Line Chemotherapy for Stage IV Breast Cancer

Breast Cancer

France
Institut Curie

Completed

Bone Marrow and Blood Samples From Patients With Metastatic Choroid Melanoma

Intraocular Melanoma
Institut Curie
National Cancer Institute, France

Recruiting

LOC-R01 Study of Lenalidomide and Ibrutinib in Association With Rituximab-Methotrexate Procarbazine Vincristin (R-MPV) (LOC-R01)

Lymphoma, Large B-Cell, Diffuse | Central Nervous System Neoplasms, Primary

France
Institut Bergonié
National Cancer Institute, France

Completed

Diffuse Large B Cell Non-Hodgkin's Lymphoma in the Vulnerable/Frail Elderly. A Multicentric Randomized Phase II Trial (FRAIL-06)

Lymphoma

France
Institut Bergonié
National Cancer Institute, France

Completed

Anastrozole or Fulvestrant in Treating Postmenopausal Patients With Breast Cancer (HORGEN)

Breast Cancer

France
Institut Curie

Unknown

Temozolomide and Bevacizumab in Treating Patients With Metastatic Melanoma of the Eye

Intraocular Melanoma

France
Azienda Ospedaliera Universitaria Policlinico "G...
Gianluca Di Bella; Antonio Micari; Giampiero Vizzari; Giorgio Quadri; Greca Zanda; Ferdinando...

Recruiting

De-escalating Antiplatelet Therapy to Assess Platelet Reactivity and Outcomes in High Bleeding Risk Patients With Recent ACS (DESC-HBR)

Coronary Artery Disease | Acute Coronary Syndrome | Dual Antiplatelet Therapy

Italy
Karolinska Institutet
Patient-Centered Outcomes Research Institute; Kaiser Foundation Research Institute

Active, not recruiting

COMparison Between All immunoTherapies for Multiple Sclerosis. (COMBAT-MS)

Relapsing-remitting Multiple Sclerosis

Sweden
Karolinska Institutet
Tata Institute of Social Sciences

Completed

Unmet Need for Massive Transfusion in Indian Trauma Patients

Trauma
Karolinska Institutet
Linkoeping University; Oregon Research Institute

Completed

Swedish Body Project for Prevention of Eating Disorders (sBodyProject)

Eating Disorders

Sweden
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Safety and Efficacy of Adipose Derived Stem Cells for Congestive Heart Failure

Ischemic Congestive Heart Failure

Mexico
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Study to Assess the Safety and Cardiovascular Effects of Autologous Adipose-Derived Stromal Cells Implantation In Patients During the Acute Recovery Phase of ST-Elevation Myocardial Infarction (Acute MI)

Acute Myocardial Infarction

United States

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