Search clinical trials for: Drug Safety

Total 274312 results

Yunfeng Cheng
Shanghai Zhongshan Hospital; Shanghai Jinshan Hospital; Macau University of Science... and other collaborators

Recruiting

The Efficacy and Safety of HCQ Plus TPO-RA in ANA Positive ITP

Immune Thrombocytopenia With Positive ANA Antibodies

China, Hong Kong, Macau
Yunfeng Cheng
Shanghai Zhongshan Hospital; Shanghai Jinshan Hospital; Macau University of Science... and other collaborators

Recruiting

The Efficacy and Safety of HCQ Plus Pred in ANA Positive ITP

Immune Thrombocytopenia With Positive ANA Antibodies

China, Hong Kong, Macau
Anhui Provincial Hospital

Not yet recruiting

Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases

Acute Graft Versus Host Disease | Malignant Hematologic Neoplasm

China
Yunfeng Cheng
Shanghai Zhongshan Hospital; Shanghai Jinshan Hospital; Macau University of Science... and other collaborators

Recruiting

The Efficacy and Safety of HCQ Plus DEX in ANA Positive ITP

Immune Thrombocytopenia With Positive ANA Antibodies

China, Hong Kong, Macau
Teva Branded Pharmaceutical Products R&D, Inc.

Not yet recruiting

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

Advanced Solid Tumors
RenJi Hospital

Recruiting

Evaluate the Safety and Efficacy of BGT007H Cell Therapy in Patients With Relapsed/Refractory Pancreatic Cancer

Tumor Pancreas

China
Shanghai Huaota Biopharmaceutical Co., Ltd.

Not yet recruiting

Long-Term Safety and Efficacy of HB0034 in Subjects With Generalized Pustular Psoriasis

Generalized Pustular Psoriasis
Febico Biomedical Corp.
National Taiwan University Hospital

Recruiting

To Evaluate Safety and Efficacy of FB-1603 in Hepatocellular Carcinoma Patient Receiving Transarterial Chemoembolization

Hepatocellular Carcinoma

Taiwan
Johnson & Johnson Consumer and Personal Products...

Not yet recruiting

Four-Week Oral Malodor and Clinical Safety for a Concentrated Cosmetic Mouthwash

Oral Malodor

United States
University of Manitoba
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements in ACPA+ Individuals (PASCOD3)

Healthy Participants

Canada
Zhejiang Cancer Hospital

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for ES-SCLC

Extensive-stage Small-cell Lung Cancer

China
Pharmaluce srl
Gruppo FarmaImpresa

Not yet recruiting

Study on the Efficacy and Safety of a Device for Post-op Recovery in Pediatric Adenectomy/Adenotonsillectomy.

Otorhinolaryngologic Diseases | Tonsillitis | Nasal Disease | Adenoidal Disorder
Universitaire Ziekenhuizen KU Leuven
Janssen Pharmaceutica

Not yet recruiting

Study on the Clinical Efficacy of Teclistamab (TECTONIC)

Hematologic Diseases | Multiple Myeloma

Belgium
Curasight
ABX CRO

Recruiting

Safety and Diagnostic Performance of uPAR PET Imaging in Localised, Untreated Prostate Cancer (uTRACE-101)

Prostate Cancer

Denmark
Pfizer

Not yet recruiting

A Study to Learn About the Safety of BESPONSA Injection in Pediatric Patients With Acute Lymphocytic Leukemia.

Acute Lymphocytic Leukemia
Bristol-Myers Squibb

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of Single Doses of BMS-986435 (MYK-224) in Healthy Chinese Participants

Healthy Volunteers

China
RenJi Hospital

Not yet recruiting

Efficacy and Safety of Rivaroxaban in the Early Postoperative Period for Patients With Bioprosthetic Valves

Anticoagulation
Beijing Chest Hospital
Anhui Chest Hospital; Changsha Central Hospital; Wuhan Institute for Tuberculosis... and other collaborators

Recruiting

The Safety and Efficacy of BDL(Bedaquiline Plus Delamanid Plus Linezolid) Regimen in Subjects With Pulmonary Infection of Multi-drug Resistant Tuberculosis (MDR-TB) or Rifampicin-Resistant Tuberculosis (RR-TB)

Pulmonary Tuberculosis

China
Shanghai Changzheng Hospital
Shanghai East Hospital; Daping Hospital, Army Medical Center of PLA

Not yet recruiting

The Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertension

Hypertension, Portal
Pfizer

Not yet recruiting

A Study to Assess Safety, Tolerability and Immunogenicity of RSVpreF From Multidose Vials in Healthy Female Adults. (Amélie)

Respiratory Syncytial Virus (RSV)

United States
Shanghai BDgene Co., Ltd.

Not yet recruiting

A Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis

Herpes Simplex Virus Type I Stromal Keratitis

China
Shanghai BDgene Co., Ltd.

Recruiting

A Study of the Safety, Tolerability and Prelinminary Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis

Herpes Simplex Virus Type I Stromal Keratitis

China
Xiangya Hospital of Central South University

Not yet recruiting

Efficacy and Safety of Early Initiation of Butylphthalide Treatment in Patients With Acute Ischemic Stroke.

Acute Ischemic Stroke
Wuhan Union Hospital, China

Not yet recruiting

Efficacy and Safety of Colchicine After PCI

Coronary Heart Disease | Percutaneous Coronary Intervention | Colchicine

China
The University of Hong Kong

Not yet recruiting

PREDICATE Trial For Respiratory Tract Infections

Respiratory Tract Infections
GCS Ramsay Santé pour l'Enseignement et la Recherche

Not yet recruiting

Evaluation of the Benefit and Safety of Localized Tissue Hydration in the Management of Chronic Low Back Pain (HTL-LOMB)

Chronic Low-back Pain

France
Medibiofarma S.L.

Recruiting

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of MBF-015 in Huntington's Disease Patients

Huntington Disease

Spain
AstraZeneca

Not yet recruiting

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma (BAIYUN)

Asthma

China
Shanghai Changzheng Hospital
The First Affiliated Hospital of Nanchang University; Shanghai Zhongshan Hospital and other collaborators

Not yet recruiting

The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis

Hypertension, Portal
Chang Gung Memorial Hospital

Not yet recruiting

Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing Loss

Sudden Hearing Loss
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Safety and Adequacy of Trans-jugular Liver Biopsy in Patients With Liver Disease: SAFE-TJLB Study

Liver Cirrhosis

India
Grupo Espanol de Trabajo en Enfermedad de Crohn...
Pfizer

Recruiting

An Active Surveillance, Post-Authorization Study to Characterize the Safety of Tofacitinib in Patients With Moderately to Severely Active Ulcerative Colitis in the Real-World Setting Using Data From the United Registries for Clinical Assessment and Research (UR-CARE) in the European Union (EU) (PASS TOFA)

Ulcerative Colitis

Belgium, Bulgaria, Greece, Lithuania
AstraZeneca

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults

Healthy Participants

United States
Luye Pharma Group Ltd.

Recruiting

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Pain, Postoperative

China
Duke University

Not yet recruiting

A Phase 1 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of JCXH-211 (SElf-Replicating RNA IL-12) Intratumoral Injection in Patients With Recurrent or Progressive High-Grade Glioma (SERIL)

Recurrent or Progressive High-grade Glioma
Shanghai Bovax Biotechnology Co., Ltd.

Not yet recruiting

A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males

Anal Cancer | HPV-Related Carcinoma | Penile Cancer | Genital Wart | AIN3 | AIN2 | PIN-1 | AIN1 | PIN2 | PIN3

China
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients

Atopic Dermatitis
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
EMD Serono Research & Development Institute, Inc.

Not yet recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

United States, Germany
IVIEW Therapeutics Inc.

Not yet recruiting

Trial to Evaluate the Efficacy And Safety of IVIEW-1201 In the Treatment of Fungal Keratitis

Fungal Keratitis
Genelux Corporation
Newsoara Biopharma Co., Ltd.

Not yet recruiting

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's of Choice Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer (VIRO-25) ((VIRO-25))

Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Advanced Non-squamous Non-small-cell Lung Cancer | Non-small Cell Lung Cancer Stage IV | Metastatic Squamous Non-Small Cell Lung Carcinoma | Non-small Cell Lung Cancer Recurrent | Metastatic Non-squamous Non Small Cell Lung Cancer and other conditions
Biocodex
Exystat

Not yet recruiting

Evaluation of the Efficacy and Safety of Stiripentol in Patients 6 Years and Older With Primary Hyperoxaluria Type 1, 2 or 3 (CRYSTAL)

Primary Hyperoxaluria Type 3 | Primary Hyperoxaluria Type 2 | Primary Hyperoxaluria Type 1
InventVacc Biologicals Inc.
Hia Consortium

Recruiting

A Study to Evaluate Safety and Immunogenicity of Haemophilus Influenzae Serotype A Vaccine

Haemophilus Influenzae Meningitis | Invasive Haemophilus Influenzae Disease

Canada
Inozyme Pharma

Not yet recruiting

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Pseudoxanthoma Elasticum | Arterial Calcification | Gene Mutations | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency | Autosomal Recessive Hypophosphatemic Rickets Type 2
Samsung Medical Center

Recruiting

Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Patients With High - Risk Localized Prostate Cancer (DESAR-H) (DESAR-H)

High Risk Prostate Carcinoma

Korea, Republic of
Guangzhou University of Traditional Chinese Medicine
Jiangsu Province Hospital of Traditional Chinese Medicine; The First Affiliated...

Not yet recruiting

Acupuncture for Enhancing Immunotherapy in Advanced NSCLC：a Pilot Study

Non-small Cell Lung Cancer | Non-Small-Cell Lung Carcinoma

China
Kaplan Medical Center

Recruiting

Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint

Osteoarthritis Thumb

Israel
Vertex Pharmaceuticals Incorporated

Not yet recruiting

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older

Cystic Fibrosis
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered Radotinib

Drug Kinetics

Korea, Republic of
Xijing Hospital

Not yet recruiting

Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer

Sintilimab | Neoadjuvant Chemotherapy | Locally Advanced Gastric Cancer
Sumitomo Pharma Co., Ltd.

Not yet recruiting

First-in-human Study to Assess the Safety, Tolerability and Immunogenicity of the Adjuvanted Universal Influenza Vaccine fH1/DSP-0546LP

Influenza

Belgium

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