Search clinical trials for: NI-0501

Total 753 results

Swedish Orphan Biovitrum

Completed

A Study to Evaluate Emapalumab in Japanese Healthy Volunteers.

Rare Diseases

Japan
Swedish Orphan Biovitrum

Completed

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Primary Hemophagocytic Lymphohistiocytosis

Spain, United States, United Kingdom, Germany, Italy, Sweden, Canada, Switzerland
Swedish Orphan Biovitrum

Recruiting

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE (EMERALD)

Systemic Lupus Erythematosus | Macrophage Activation Syndrome | Still Disease | Secondary Hemophagocytic Lymphohistiocytosis | SJIA | AOSD | MAS

United States, Belgium, Italy, Netherlands, United Kingdom, China, France, Spain, Czechia, Canada, Sweden, Japan, Germany, Poland
Swedish Orphan Biovitrum

Completed

First in Human Study of an Anti-IFN Gamma Monoclonal Antibody in Healthy Volunteers

Healthy Volunteers

United Kingdom
Swedish Orphan Biovitrum
Seventh Framework Programme

Completed

Study to Investigate Safety, Efficacy of an Anti-IFNγ mAb in Children With Primary Haemophagocytic Lymphohistiocytosis

Primary Haemophagocytic Lymphohistiocytosis

United States, Sweden, Spain, Italy, Germany, United Kingdom
Swedish Orphan Biovitrum
Light Chain Bioscience - Novimmune SA

Terminated

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLH

Hemophagocytic Lymphohistiocytoses

United States
Swedish Orphan Biovitrum
Seventh Framework Programme

Completed

A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Hemophagocytic Lymphohistiocytosis

United States, France, Italy, Spain, United Kingdom
Swedish Orphan Biovitrum
PRA Health Sciences; Cromsource; BioMérieux; Q2 Solutions; Cytel Inc.; ABF Pharmaceutical...

Terminated

Study to Investigate the Pharmacokinetics, Pharmacodynamics and Assess the Efficacy and Safety to Support Dose Selection of Emapalumab in Pre-empting Graft Failure in Patients at High Risk After HSCT.

Graft Failure

Canada, Australia, Israel
Swedish Orphan Biovitrum

Completed

A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Arthritis, Juvenile | Lymphohistiocytosis, Hemophagocytic | Macrophage Activation Syndrome | Adult Onset Still Disease

United States, Spain, United Kingdom, France, Italy
Hong Kong Baptist University
The Hong Kong Jockey Club Charities Trust

Completed

The Distribution of Body Constitutions Among Hong Kong Elderly Population: A Cross-sectional Study

Nine Body Constitutions

China
University of Ulster
University College Cork; Dublin City University; Northern Ireland Chest Heart...

Recruiting

The Youth - Physical Activity Towards Health Intervention in Northern Ireland (Y-PATH NI)

Physical Inactivity

United Kingdom
Swedish Orphan Biovitrum
Harvard Medical School (HMS and HSDM); Brigham and Women's Hospital

Completed

Evaluation of IFNγ and Inflammatory Mediators in Patients With Hemophagocytic Lymphohistiocytosis

Hemophagocytic Lymphohistiocytoses

United States
Swedish Orphan Biovitrum
PRA Health Sciences; BioMérieux; Cytel Inc.

Terminated

A Clinical Study to Investigate Interferon Gamma (IFNɣ) Signature in Patients Post HSCT and in Patients With Impaired HSC Proliferation Pre-transplant

Graft Failure

Italy, Belgium, United Kingdom, France, Germany, Netherlands
Hospital Psiquiatrico Infantil Dr. Juan N. Navarro...

Unknown

Anti-inflammatories and Adolescent Schizophrenia

Schizophrenia

Mexico
Light Chain Bioscience - Novimmune SA

Completed

NI-0401 in Patients With Acute Renal Allograft Rejection

Acute Renal Transplant Rejection

France
Light Chain Bioscience - Novimmune SA

Recruiting

A Study of NI-1801 in Patients With Mesothelin Expressing Solid Cancers

Triple Negative Breast Cancer | Epithelial Ovarian Cancer | Non-squamous Non-small-cell Lung Cancer

Italy, France
Indonesia University

Not yet recruiting

Effectiveness of HVNI in Preterm Infants With Moderate Respiratory Distress

Respiratory Distress, Newborn
SymBio Pharmaceuticals

Completed

Study of SyB L-0501 to Treat Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

Japan
SymBio Pharmaceuticals

Completed

Efficacy and Safety Study of SyB L-0501 for Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Japan
Shanghai Zhongshan Hospital

Recruiting

The Risk Factors of Cardiovascular Disease in Elderly Diabetic Patients: A Prospective Cohort Study

Cardiovascular Diseases | Diabetes Mellitus | Complication Diabetic

China
Jiangsu Taizhou People's Hospital

Recruiting

Clinical Value of Prick Therapy Combined With Wheat Grain Moxibustion in the Treatment of Spleen Deficiency and Dampness Obstructed Cancer

Pricking Therapy on the Back Shu Points | Wheat Grain Moxibustion on the Back Shu Points

China
Queen's University, Belfast
AWARE NI; Northern Ireland Public Health Research Network

Completed

Developing E-health Services (DES): The Feasibility and Acceptability of Video-conferencing for Adults With Depression (DES)

Depression

United Kingdom
Light Chain Bioscience - Novimmune SA

Completed

First in Human Study of NI-0701 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Guangdong Provincial Hospital of Traditional Chinese...

Completed

The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis

Severe Sepsis

China
Changhua Christian Hospital

Terminated

Simultaneously Using Traditional Chinese Medicine (Si-Ni-Tang) to Treat Septic Shock Patients

Septic Shock

Taiwan
Hôpital NOVO

Recruiting

Efficacy of Non-instrumental Pleural Chest Physiotherapy (KINEPANCH)

Infectious Pleural Effusion

France
Kangen Pharmaceuticals, Inc

Completed

A Dose Ranging Study Evaluating Efficacy and Safety of NI-03 (Tactic)

Chronic Pancreatitis

United States, Russian Federation, Ukraine
Light Chain Bioscience - Novimmune SA

Completed

Study of an Anti-TLR4 mAb in Rheumatoid Arthritis

Rheumatoid Arthritis

Serbia, Bosnia and Herzegovina, Bulgaria, Georgia, Hungary, Moldova, Republic of, Poland
Queen's University, Belfast
College of Optometrists

Completed

The Northern Ireland Sensory Ageing Study (NISA)

Aging

United Kingdom
Queen's University, Belfast
University of Sussex

Unknown

Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision

Retinitis Pigmentosa | Low Vision | Albinism | Stargardt Disease 1 | Stargardt Disease 3 | Stargardt Disease 4

United Kingdom
Cellivery Therapeutics, Inc.
Labcorp Corporation of America Holdings, Inc

Suspended

iCP-NI - Safety, Tolerability, Pharmacokinetic, and Immunogenicity Study in Healthy Male and Female Subjects

Healthy Volunteers

United States
University Hospital, Montpellier

Completed

Criteria Associated With Patient Willingness to Participate in Biomedical Research (PROTOACCEPT)

Consulting in Pneumology Department, But Not for Oncology or Tobacology

France
Queen's University, Belfast
University of Sussex

Unknown

Determining the Clinical Utility of Using Virtual Reality Headsets to Assess Visual Function in Those With Glaucoma.

Glaucoma

United Kingdom
Queen's University, Belfast

Completed

A Systematic Study of Retinal Structure and Function in Diabetic Macular Oedema

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United Kingdom
University of Vienna
Medical University of Vienna; Flinders University; Queensland University of Technology and other collaborators

Completed

Dietary Nitrate, Vascular Function and Inflammation

Inflammation | Hypertension

Austria
Rennes University Hospital

Recruiting

Microsampling Approach for Monitoring of Kinase Inhibitor Targeted Therapies (MISTIK)

Blood Concentrations of Nine Anti-cancer Drugs : Axitinib, Olaparib, regorafénib, Cabozantinib, Niraparib, Talazoparib, Palbociclib, Abemaciclib, Tucatinib

France
Light Chain Bioscience - Novimmune SA
M.D. Anderson Cancer Center

Completed

Study to Evaluate Interferon Gamma (IFNγ) and Other Inflammatory Mediators in Patients With Malignancy-Associated Hemophagocytic Lymphohistiocytosis (M-HLH)

Hemophagocytic Lymphohistiocytosis

United States
University of North Carolina, Chapel Hill
Gilead Sciences; Duke University

Recruiting

Pilot Mobile Medical Unit Study for I'm Fully Empowered4Her (IFE4Her)

PrEP | HIV Prevention | Women's Health | Prevention | Mobile Health | Pre-exposure Prophylaxis

United States
Alanya Alaaddin Keykubat University

Completed

Comparison of Neuromuscular Integrative Activity and Pilates on Sedentary Females

Healthy | Sedentary Behavior | Womens's Health

Turkey
BioSerenity

Unknown

evaluatioN de la perfOrMAnce De Capteurs E-textiles (NOMADE)

Healthy Volunteers Without Any Cardiac or Any Neurological Disorders

France
Columbia University
Solstice Neurosciences

Completed

Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia

Focal Dystonia

United States
UMN Pharma Inc.

Completed

Immunogenicity, Safety and Optimal Dose Finding Study of Recombinant Influenza H5N1 Vaccine in Healthy Young Adults

Virus Diseases | Influenza

Japan
bo xu

Not yet recruiting

Effect of Subanesthetic Dose Esketamine on Propofol-refentanil Closed-loop Targeted Controlled Infusion

Esketamine
Light Chain Bioscience - Novimmune SA

Terminated

Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody (PIANO)

Primary Biliary Cirrhosis

Italy, United Kingdom
North Dakota State University
Neuropsychiatric Research Institute, Fargo, North Dakota

Completed

The Effect of Nutrient Intake on the Microbiome, Weight, and Glucoregulation (NI-MWG) (NI-MWG)

Obesity | Type2 Diabetes

United States
Charles University, Czech Republic

Not yet recruiting

Variability of Healthy People and People After Stroke Results in the Nine Hole Peg Test

Motor Activity

Czechia
Brugmann University Hospital

Completed

Correlation Between the 'Nine Holes Peg Test' Performance and the Triple Stimulation Technique Within a Group a Patients With Multiple Sclerosis

Multiple Sclerosis

Belgium
WANG Yan-bin

Unknown

Mitochondrial Apoptotic Pathway Induced by Myocardial Ischemia-Reperfusion Injury in Human

Ischemic Postconditioning | Ischemia-reperfusion(I/R) | Cardiopulmonarybypass | the Mitochondrial Pathway

China
UMN Pharma Inc.

Completed

Immunogenicity and Safety Study of a Booster Vaccination With a Recombinant H5N1 Influenza HA Vaccine in Primed Adults

Influenza

Japan
University Hospital, Geneva

Completed

Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPed-NI) (NavPed-NI)

Respiratory Failure | Mechanical Ventilation Complication

Switzerland

Search clinical trials for: NI-0501

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