Search clinical trials for: SC-58635

Total 2677 results

M.D. Anderson Cancer Center
National Comprehensive Cancer Network

Completed

CPT-11/Cisplatin and Celecoxib With Radiation Therapy for Patients With Unresectable Non-Small Cell Lung Cancer (NSCLC)

Lung Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

Familial Adenomatous Polyposis

United States
Michele Brignole

Completed

Optimization of Coronary Sinus Lead Placement Targeted to the Longest Right-to-Left Delay (Opsite 2)

HF Patient

Italy
University of Utah
National Cancer Institute (NCI)

Suspended

Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer

Oral Cavity Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal... and other conditions

United States
National Cancer Institute (NCI)

Completed

Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis

Colorectal Cancer | Familial Adenomatous Polyposis

United States
University of Washington
National Cancer Institute (NCI)

Terminated

A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With Metastatic Colorectal Cancer (ADAPT)

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
National Cancer Institute (NCI)

Completed

Celecoxib in Treating Postmenopausal Women Who Are Undergoing Surgery for Invasive Breast Cancer

Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Celecoxib and Recombinant Interferon Alfa-2b in Metastatic Kidney Cancer Who Have Undergone Surgery

Renal Cell Cancer | Stage IV Renal Cell Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Unresectable Triple-Negative Breast Carcinoma

United States
Emory University
National Cancer Institute (NCI); Genentech, Inc.

Completed

Secondary Primary Tumor Prevention With EGFR, OSI-774, and Cyclooxygenase-2

Head and Neck Cancer

United States
National Cancer Institute (NCI)

Completed

Celecoxib in Preventing the Damaging Effects of Sunburn in Healthy Volunteers

No Evidence of Disease

United States
National Cancer Institute (NCI)

Completed

Celecoxib in Decreasing the Damaging Effects of Sunburn in Healthy Volunteers

No Evidence of Disease

United States
National Cancer Institute (NCI)

Completed

Celecoxib and Erlotinib in Treating Former Smokers With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma

Refractory Melanoma | HLA-A2 Positive Cells Present

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Terminated

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions

United States
Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Completed

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Prognostic Stage I Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
Assiut University

Completed

Reproductive Outcome in Assisted Conception Cycles

Infertility

Egypt
City of Hope Medical Center

Completed

Cyclophosphamide With or Without Celecoxib in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Fallopian Tube Cancer | Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Carcinoma in the Liver

United States
University of Chicago
National Cancer Institute (NCI)

Terminated

Capecitabine and Celecoxib in Patients With Solid Cancers That Have Been Previously Treated With Standard Therapies

Unspecified Adult Solid Tumor, Protocol Specific

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia

Cervical Carcinoma | Cervical Intraepithelial Neoplasia Grade 2/3 | Stage 0 Cervical Cancer

United States
City of Hope Medical Center
OSI Pharmaceuticals

Completed

Erlotinib Hydrochloride With or Without Celecoxib in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Celecoxib in Treating Patients With Stage IIIB or Stage IV Recurrent Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Completed

Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps

Rectal Cancer | Colon Cancer

United States
National Cancer Institute (NCI)

Completed

Celecoxib in Treating Patients With Bladder Cancer

Recurrent Bladder Cancer

United States
SC Medica

Recruiting

Post-marketing Clinical Follow-up of the Medical Device DIVA®

Lumbar Disc Herniation

France
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy (RAVOS)

Sickle Cell Disease | Sickle Cell SC Disease | Sickle Cell-SS Disease | Sickle Cell Retinopathy

Netherlands
SC Medica

Recruiting

Evaluation of the Efficacy and Safety of the FACET FIXation Implant. (FACETFIX)

Degenerative Lumbar Spinal Stenosis

France
SC Medica

Not yet recruiting

Effectiveness and Safety of the Facet Fixation (FFX®) Implant in the Treatment of Degenerative Lumbar Spinal Stenosis (FFX® RCT)

Degenerative Lumbar Spinal Stenosis
Klein Buendel, Inc.
National Institute on Minority Health and Health Disparities (NIMHD); Hilton...

Completed

PINPOINT: Gaming Technology for SCD Pain (Pinpoint II)

Sickle Cell Disease | Sickle Cell Anemia in Children | Sickle Cell Thalassemia | Sickle Cell SC Disease

United States
StemCells, Inc.

Terminated

Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury

Cervical Spinal Cord Injury | Spine Injury | Cervical Spine Injury

United States, Canada
argenx

Recruiting

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease. (UplighTED)

Thyroid Eye Disease

United States
Hangzhou Sumgen Biotech Co., Ltd.

Recruiting

SG301-SC Injection Safety Study in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE)

China
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Safety and Efficacy of IBI306 in Chinese Subjects With Non-familial Hypercholesterolemia

Hypercholesterolemia

China
argenx

Recruiting

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease (UplighTED)

Thyroid Eye Disease

United States
Tami D. John
Baylor College of Medicine; The Methodist Hospital Research Institute

Terminated

Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP (SCALLOP)

Sickle Cell Disease | Hemoglobin SC

United States
SC Aromaarmony SRL

Unknown

Effects of Arom Digest Slim on Metabolic Profile and Food Behaviour in Overweight Persons

Metabolic Syndrome

Romania
argenx

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia (ADVANCE SC)

Primary Immune Thrombocytopenia

United States, France, Georgia, Germany, Italy, Japan, Poland, Russian Federation, Spain, Turkey, United Kingdom, Argentina, Australia, Bulgaria, Chile, China, Denmark, Greece, Ireland, Israel, Jordan, Korea, Republic of, Mexico, New... and more
National Cancer Institute (NCI)

Completed

Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers

Colorectal Neoplasm | Hereditary Nonpolyposis

United States
Baylor College of Medicine
Boston Children's Hospital

Terminated

Oral Magnesium Pidolate, Hemoglobin SC Disease, MG Pidolate

HEMOGLOBIN SC DISEASE

United States
ViiV Healthcare
GlaxoSmithKline

Recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
University of Michigan
Patient-Centered Outcomes Research Institute; Medical University of South Carolina and other collaborators

Completed

Taking Charge of Systemic Sclerosis (TOSS)

Scleroderma

United States
StemCells, Inc.

Terminated

Long-Term Follow-up Safety Study of Human Central Nervous System Stem Cells in Subjects With Geographic Atrophy of Age-Related Macular Degeneration

Age-Related Macular Degeneration | Geographic Atrophy

United States
University of California, San Diego
University of Oklahoma; University of Southern California; Children's Bureau... and other collaborators

Completed

Evaluating Trauma-Informed, Evidence-Informed Interventions for Latino Families Experiencing Domestic Violence

Interpersonal Relations

United States
University of the State of Santa Catarina

Terminated

Pulmonary Rehabilitation in Functional Outcomes and Its Relationship With Morbidity and Mortality in Patients With COPD

Pulmonary Disease, Chronic Obstructive

Brazil
Fundacion Nacional de Dermatologia
Hospital Dermatologico de Jorochito; Ministerio de Salud de Bolivia, Programa... and other collaborators

Completed

Oral Miltefosine Plus Topical Paromomycin In American Cutaneous Leishmaniasis

Cutaneous Leishmaniasis, American

Bolivia
Alessandro Haupenthal
Santa Catarina Federal University

Unknown

Effect of Therapeutic Techniques on Leg Stretching in Healthy Subjects

Healthy | Adult

Brazil
Universidade Federal de Santa Catarina

Completed

Effect of Prebiotic or Synbiotic on Inflammatory Response and Indicators of Nutritional Status in Obesity

Morbid Obesity

Brazil
Hoffmann-La Roche
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis

Moderate to Severe Ulcerative Colitis

United States, Australia, Thailand, Poland, Russian Federation, Japan, Colombia, Spain, Turkey, Romania, India, Slovakia, France, Hungary, South Africa, Belgium, Bulgaria, Germany, Italy, Mexico, Serbia, Ukraine, United Kingdom
Eli Lilly and Company

Completed

A Study of LY3461767 in Healthy Participants

Healthy

United States, Singapore

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