Search clinical trials for: Tapentadol extended-release tamper-resistant formulation

Total 2850 results

Hangzhou Highlightll Pharmaceutical Co., Ltd

Completed

Evaluation of TLL-018 Extended and Immediate Release Formulation for Bioequivalence Testing in Healthy Chinese Subjects

Atopic Dermatitis

China
Grünenthal GmbH

Completed

Pharmacokinetic Characterization of Two Novel CG5503 Tablet Formulations in Healthy Volunteers

Pharmacokinetics

Germany
Astellas Pharma Inc

Completed

Oral Multiple-dose Study in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess Bioequivalence of a New Tapentadol Extended-Release Tablet With Respect to a Tapentadol Extended Release Tablet Under Fasted Conditions in Healthy Subjects

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pivotal Study to Evaluate the Bio-equivalence of the Tapentadol Extended-Release (ER) Tamper-resistant Formulation (TRF) Tablet to the Current Tapentadol ER Prolonged-release 2 (PR2) Tablet

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Phase 1 Pharmacokinetic Study of Tapentadol Prolonged-Release 250 Milligram (mg) Formulation in Healthy Participants

Healthy

Netherlands
Novo Nordisk A/S

Recruiting

A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or Obesity

Obesity | Overweight

United States
AbbVie

Not yet recruiting

A Study to Assess Relative Bioavailability and Food Effect of ABBV-668 Extended-Release Formulations in Adult Participants

Healthy Volunteers
Bayer

Not yet recruiting

A Study to Learn About the Taste of Vericiguat Given in Liquid Form in Healthy Male Participants Aged 18 to 45 Years

Heart Failure

Germany
Sinovac Life Sciences Co., Ltd.

Not yet recruiting

Phase I Clinical Trial of PCV24 in Adults

Pneumococcal Infectious Disease

China
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
EMD Serono Research & Development Institute, Inc.

Recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

Japan
Nanexa AB
Profil Institut für Stoffwechselforschung GmbH

Not yet recruiting

Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D

Type 2 Diabetes
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Tolerability and Acceptance of Two Oral Hydrocortisone Compounding Formulation for Pediatrics

Adrenal Insufficiency

Spain
Jiaxing AnDiCon Biotech Co.,Ltd

Recruiting

Comparative Bioavailability Study of Tablet and Granule Formulations of ADC189 and the Study of Ultra-high Dose

Healthy Volunteer

China
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8 | Resectable Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Ductal Adenocarcinoma

United States
Supplement Formulators, Inc.
Compound Solutions Inc.

Recruiting

Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms

Gut Health

United States
Bayer

Recruiting

A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants

Soil-transmitted Helminth Infection | Onchocerciasis (River Blindness)

Germany
Boehringer Ingelheim

Recruiting

A Study in Healthy People to Compare How 2 Different Low Dose Formulations of BI 1015550 Are Taken up in the Body

Healthy

Germany
AbbVie

Recruiting

A Study in Healthy Adult Participants to Assess the Pharmacokinetics, Immunogenicity, Safety, and Tolerability of a Ravagalimab Subcutaneous Formulation in a Pre-Filled Syringe

Healthy Volunteers

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Not yet recruiting

Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Pfizer

Not yet recruiting

A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants

Healthy Participants | Biological Availability
Pfizer

Recruiting

A Study to Learn How Different Forms of the Study Medicine Called PF-06954522 Are Taken up Into the Blood in Healthy Adults

Healthy Participants

United States
Boehringer Ingelheim

Recruiting

A Study in Healthy People to Compare How 2 Different High Dose Formulations of BI 1015550 Are Taken up in the Body

Healthy

Germany
Opella Healthcare Group SAS, a Sanofi Company

Not yet recruiting

Bioavailability Study of Magne-B6 New Formulation

Healthy Volunteers
University of Redlands

Not yet recruiting

Pharmacokinetics of Melatonin Administered in Oral, Lotion, and Bubble Bath Formulations

Sleep

United States
Amazentis SA
Mprex Healthcare Pvt. Ltd.

Recruiting

Bioavailability of Three Mitopure Formulations

Healthy Adults

India
Changchun BCHT Biotechnology Co.
The First Affiliated Hospital of Yunnan University of Traditional Chinese... and other collaborators

Not yet recruiting

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of the Fully Human Anti-tetanus Toxin Monoclonal Antibody A82 / B86 Injection Combination Formulation

Clostridium Tetanus
Pharmacotherapies for Alcohol and Substance Use...
Yale University; United States Department of Defense; VA Connecticut Healthcare... and other collaborators

Not yet recruiting

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

Post Traumatic Stress Disorder (PTSD) | Alcohol Use Disorder (AUD)

United States
Gut-Brain-Axis Therapeutics Inc.
Pitt Hopkins Research Foundation

Recruiting

Microbiota Transfer Therapy for Children and Adults With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders

Pitt Hopkins Syndrome

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

Open-label Trial Characterizing the PK of 3 SC Olanzapine Extended-release Formulations in Participants With Schizophrenia/Schizoaffective Disorder

Schizophrenia, Schizoaffective Disorder

United States
ViiV Healthcare
GlaxoSmithKline

Recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
Queen Mary University of London
Geistlich Pharma AG

Not yet recruiting

Hyaluronic Acid and Polynucleotides for Supra-bony Defects

Periodontal Diseases | Wound Heal | Periodontal Pocket | Periodontal Attachment Loss | Periodontal Inflammation

United Kingdom
Pharma Nueva

Not yet recruiting

A Bioequivalence Study of Two Formulations of 10-mg Empagliflozin Tablets in Healthy Thai Volunteers Under Fasting Conditions

Healthy Vollunteer
Friends Research Institute, Inc.

Not yet recruiting

Buprenorphine for Individuals in Jail

Opioid Use Disorder

United States
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
Shanghai Institute Of Biological Products
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

A Clinical Trial of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients.

Advanced Solid Tumor
Rovi Pharmaceuticals Laboratories

Recruiting

Pharmacokinetics, Safety and Tolerability of Different Formulations and Dose Strengths of Quarterly Risperidone (QUAR) in Patients With Schizophrenia (QUARTZ)

Schizophrenia

Jordan
Shionogi

Recruiting

A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants

Healthy Volunteers

United States
University of Thessaly

Recruiting

Tapentadol vs Tramadol in Total Knee Arthroplasty

Chronic Pain | Total Knee Replacement | Post-operative Pain

Greece
United States Army Research Institute of Environmental...

Not yet recruiting

Effect of Ration Formulations on Warfighter Energy Balance and Physical Performance During a Field Training Exercise

Healthy Volunteers

United States
Sanofi Pasteur, a Sanofi Company

Recruiting

Study of a Respiratory Syncytial Virus Candidate Formulation in Adults Aged 60 Years and Older

Healthy Volunteers | Respiratory Syncytial Virus Infection

Australia, Dominican Republic, Honduras
Dompé Farmaceutici S.p.A

Recruiting

A Study to Evaluate Safety and Efficacy of a New Formulation of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution in Patients With Dry Eye Disease (REDUCO)

Dry Eye Disease

United States, Italy
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

Methamphetamine-dependence | Methamphetamine Abuse
Ruijin Hospital

Not yet recruiting

A Study on the Prophylactic Use of Antibiotics Within 72 Hours After Acute Burn Injury in Patients

Burn Infection
Zuyderland Medisch Centrum

Not yet recruiting

Effect of Honey For CIN II (HoneyForCIN2)

Cervical Intraepithelial Neoplasia-II | High Risk Human Papillomavirus
Atea Pharmaceuticals, Inc.

Recruiting

Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and Ruzasvir

Healthy Volunteer Study

United States
Pfizer

Recruiting

A Study to Learn About the Safety and Immune Response of a New Pneumococcal Vaccine in Adults

Pneumococcal Disease

United States
Al-Azhar University

Not yet recruiting

Efficacy of Manuka Honey Nano-Formulation in the Treatment of Acne Vulgaris

Acne Vulgaris
Pontificia Universidad Catolica de Chile

Recruiting

PK of Lidocaine/Tetracaine and PD Derived From a New Topical Formulation for Treatment of Neuropathic Pain. (PK/PDLido)

Neuralgia | Neuropathic Pain | Local Anesthetic Complication | Lidocaine Adverse Reaction

Chile
National Cancer Institute (NCI)

Recruiting

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United States

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