Search clinical trials for: dosing immunosuppression

Total 2030 results

Philipps University Marburg Medical Center

Active, not recruiting

Viral Load Guided Immunosuppression After Lung Transplantation (VIGILung)

Transplantation Lung

Austria, Germany
Kevin W Hatton, MD, PhD

Terminated

Repeated Amiodarone Dosing In Cardiac surgicaL Procedures (RADICAL)

Atrial Fibrillation

United States
University of Florida
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine (PPM - Pro)

Liver Transplant | Kidney Transplant

United States, Singapore
Emory University

Completed

Bela 8 Week Dosing

Kidney Transplantation

United States
Medical University of South Carolina
Astellas Pharma Inc

Completed

Dosing Requirements of Astagraf XL® in African American Kidney Transplant Recipients

Immunosuppression

United States
University of Illinois at Chicago
Astellas Pharma US, Inc.

Completed

A Pharmacokinetic Analysis of Tacrolimus ER Dosing in Obese Kidney Transplant Recipients (Tacrolimus ER)

Kidney Transplantation

United States
University of Cincinnati
Roche Pharma AG; University of Tennessee

Completed

A Trial of Two Daclizumab Dosing Strategies vs. No Induction Treatment With Tacrolimus, Mycophenolate Mofetil , & Steroids for the Prevention of Acute Allograft Rejection in Simultaneous Kidney/Pancreas Transplant Recipients

Acute Allograft Rejection in Simultaneous Kidney/Pancreas Transplant Recipients

United States, Canada
Nova Scotia Health Authority

Completed

Intensified Dosing of Cellcept (Mycophenolate Mofetil) in Kidney Transplantation

Acute Rejection of Renal Transplant

Canada
Merck Sharp & Dohme LLC

Not yet recruiting

Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016)

Non-alcoholic Fatty Liver Disease | Liver Disease | Nonalcoholic Fatty Liver Disease | Metabolic Dysfunction-Associated Steatotic Liver Disease
ARCAGY/ GINECO GROUP
Horizon 2020 - European Commission

Not yet recruiting

Utility of Adjusting Chemotherapy Dose & Dosing Schedule With the SALVage Weekly Dose-dense Regimen in Patients With Poor Prognostic OVARian Cancers Based on the Tumor Unfavorable Primary Chemosensitivity and Incomplete Debulking Surgery (SALVOVAR)

Ovarian Cancer

France
CHU de Reims

Not yet recruiting

Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma (Myomachia)

Hepatocellular Carcinoma | Sarcopenia

France
Laure Pittet, MD-PhD

Recruiting

Registry of Vaccine Responses in Immune Compromised Patients (REVAPI)

Immunosuppression

Switzerland
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Viral Infection of HSPC Impacts Hematopoiesis (MEGAHOST)

SARS-CoV-2 | HIV-1

France
University of Hamburg-Eppendorf

Not yet recruiting

Model-informed Precision Dosing for Linezolid (LINEMAP)

Gram-Positive Bacterial Infections
Medical University of South Carolina

Recruiting

tFUS Induced Transient Scotoma for Individual Dosing

Healthy

United States
University Hospital, Ghent

Recruiting

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) (PADECMO)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin | Cefazolin

Belgium
National University Hospital, Singapore

Not yet recruiting

A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers (VALUE-CHECK)

Carcinoma, Hepatocellular | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Oesophageal Cancer | GastroEsophageal Cancer

Singapore
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Micro-dosing Indocyanine Green (ICG) in Children

Genitourinary Disease | Perfusion | Fluorescence Imaging | Gastrointestinal Tract Disorders

United Kingdom
Ontario Clinical Oncology Group (OCOG)
Pfizer

Not yet recruiting

Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma (EMBRACE)

Refractory Multiple Myeloma

Canada
Papworth Hospital NHS Foundation Trust
Medical Research Council; University of Oxford; University of Liverpool

Not yet recruiting

PrOtamIne doSing clOt imagiNg (POISON) Study (POISON)

Cardiac Surgery

United Kingdom
University Hospital, Ghent
Belgium Health Care Knowledge Centre

Not yet recruiting

Proactive TDM Versus Standard Use of Biologics in Psoriasis (HELIOS)

Psoriasis Vulgaris

Belgium
American Society of Clinical Oncology
Patient-Centered Outcomes Research Institute

Not yet recruiting

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

Metastatic Breast Cancer
Jessica Merlin
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment (TREETOP)

Chronic Pain | Opioid Use Disorder

United States
CT Glaucoma Associates

Recruiting

How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

Glaucoma, Open-Angle | Glaucoma; Drugs

United States
Peking Union Medical College Hospital
Xiangya Hospital of Central South University; Ruijin Hospital; China-Japan Friendship...

Recruiting

The Study of Monitoring and Dosing Guidance of Direct Oral Anticoagulants Based on Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics

Pulmonary Embolism

China
Neonc Technologies, Inc.

Not yet recruiting

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

High Grade Glioma | Pineocytoma | Diffuse Midline Glioma, H3 K27M-Mutant | Spinal Cord Tumor | Pediatric Tumor of CNS | Pediatric Tumor of Brain | Pediatric Tumor of Brain Stem | Choroid Plexus Carcinoma, Childhood
University Hospital, Limoges

Not yet recruiting

Evaluation of the Benefits of Administering Immunosuppressive Drugs as Single Daily Doses Over the First Year After Liver Transplantation (EASY) (EASY)

Liver Transplantation | Immunosuppression

France
Technical University of Munich
Hannover Medical School; University Hospital Heidelberg; Klinikum der Universität... and other collaborators

Recruiting

The Transplant Cohort of the German Center for Infection Research

Infections | Immunosuppression | Transplant Failure | Transplant Complication

Germany
ReAlta Life Sciences, Inc.

Not yet recruiting

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease (AURORA)

Steroid Refractory GVHD
University of Texas Southwestern Medical Center

Not yet recruiting

Use of DNA Testing and Gene Expression Profiling to Help Transition Kidney Transplant Recipients to Belatacept-only Immunosuppression

Kidney Transplant Immunosuppression

United States
Children's Mercy Hospital Kansas City
Indiana Clinical and Translational Sciences Institute

Recruiting

IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver Disease (IMPROVE-FALD)

Fontan Circulation

United States
Nantes University Hospital

Recruiting

Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation (EDearly AF)

Atrial Fibrillation

France
Kathelijn Fischer
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Pharmacokinetic-guided Dosing of Emicizumab (DosEmi)

Adolescent | Child | Hemophilia A With Inhibitor | Adult | Hemophilia A Without Inhibitor | Hemophilia A, Severe

Netherlands
University of Virginia
Rutgers University; Haydom Lutheran Hospital

Not yet recruiting

Precision Rifampin Trial for Personalized Dosing (P-RIF)

Tuberculosis
Rhode Island Hospital
Brown University

Not yet recruiting

Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose (Optimal Bup)

Opioid Use Disorder
Qilu Hospital of Shandong University

Recruiting

Clemastine Fumarate in the Treatment of Neurodevelopmental Delays in Williams Syndrome

Child | Williams Syndrome | Neurodevelopmental Delay

China
Bayer

Recruiting

An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)

Preterm Infants | Retinopathy of Prematurity

United Kingdom
Centre Hospitalier Universitaire de Nice

Recruiting

Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease (PPi-DIA)

Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control

France
University Hospital, Rouen

Not yet recruiting

Efficacy and Safety of Immunosuppression, Caplacizumab and Plasma Infusion Without Therapeutic Plasma Exchange in Immune-mediated Thrombotic Thrombocytopenic Purpura: Multicentric Non-inferiority Single-arm Study (PEX-FREE)

Thrombotic Microangiopathies
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Recruiting

Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (XT1061)

Chronic Hepatitis b

China
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus (ELIMINATE)

Liver Transplant

United States
Florida Atlantic University

Not yet recruiting

Machine Learning and 3D Image-based Modeling for Body Weight Estimation.

Weight, Body | Drug Dose | No Specific Conditions | Weight-Estimation
University of Manitoba

Not yet recruiting

Croup Dosing Study

Croup
VA Sierra Nevada Health Care System
Merck Sharp & Dohme LLC

Not yet recruiting

Evaluation of PCV15 Vaccination Among PPSV23-experienced, Immunocompromised Elderly Veterans

Immunosuppression | Pneumococcal Vaccines
Edward Geissler
Chiesi Pharmaceuticals GmbH

Recruiting

Tacrolimus C:D Ratio Measured in Renal Transplant Recipients Treated With Once-daily Prolonged-release Drugs (TaC:Drop)

Immunosuppression

Germany
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

Myeloproliferative Disorders | Acute Leukemia | Myelodysplastic Syndrome

United States
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
Central Adelaide Local Health Network Incorporated
National Health and Medical Research Council, Australia; University of Adelaide and other collaborators

Not yet recruiting

Safety and Immunogenicity of Recombinant Zoster Vaccine for Kidney Transplant Recipients (SIR ZOSTER)

Immunosuppression | Vaccine Response Impaired
Police General Hospital, Thailand

Not yet recruiting

Effectiveness of Repeated Amiodarone Dosing Regimen Versus Standard Dosing Regimen in Atrial Fibrillation Patient With Rapid Ventricular Response

Atrial Fibrillation
hemotune AG

Not yet recruiting

First in Human Trial to Assess the Safety of HemoSystem REBOOT in Patients With Sepsis-induced Immunosuppression (RESTORE I)

Septic Shock

Switzerland

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