Search clinical trials for: roflumilast

Total 119 results

University of Calgary

Not yet recruiting

Roflumilast and TMS Motor Plasticity

TMS Induced Synaptic Plastcity

Canada
Rao Dermatology

Recruiting

Visualization of Topical Zoryve vs. Vehicle Using Line Field Optical Coherence Tomography in Healthy Skin

Healthy Skin

United States
Mansoura University

Not yet recruiting

Efficacy of Roflumilast in Prevention of Peripheral Neuropathy

Peripheral Neuropathy
Tanta University

Not yet recruiting

Role of Roflumilast in Ulcerative Colitis

Ulcerative Colitis
Jacob Pontoppidan Thyssen
The Novo Nordic Foundation

Recruiting

Treatment of Chronic Hand Eczema With Oral Roflumilast (HERO)

Chronic Hand Eczema

Denmark
Elpen Pharmaceutical Co. Inc.

Recruiting

Clinical Study for the Effectiveness of Roflumilast Treatment in COPD Greek Patients Based on Standard Clinical Practice. (ARGO)

Copd | COPD Exacerbation

Greece
Children's Hospital Medical Center, Cincinnati
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge

Fragile X Syndrome

United States
Sadat City University

Recruiting

The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients

Major Depressive Disorder

Egypt
Maastricht University Medical Center

Recruiting

Cognitive Effects of Roflumilast in (a)MCI and Mild Dementia Patients (ROMEMA)

Mild Cognitive Impairment | Mild Dementia | Amnestic Mild Cognitive Disorder

Netherlands
Chiesi Farmaceutici S.p.A.

Recruiting

A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR) (PILLAR)

Chronic Obstructive Pulmonary Disease

Bulgaria, United States, Argentina, Austria, Bosnia and Herzegovina, Chile, Croatia, Czechia, Estonia, Germany, Greece, Hungary, Israel, Latvia, Mexico, Netherlands, New Zealand, North Macedonia, Poland, Romania, Russian Federation and more
The University of Hong Kong

Recruiting

Roflumilast in Non-CF Bronchiectasis Study (2019)

Non-cystic Fibrosis Bronchiectasis

Hong Kong
Johns Hopkins University
Patient-Centered Outcomes Research Institute; University of Illinois at Chicago

Recruiting

Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) (RELIANCE)

Chronic Bronchitis | Chronic Obstructive Pulmonary Disease Severe

United States
Arcutis Biotherapeutics, Inc.

Completed

Long-Term Safety of ARQ-154 Foam in Subjects With Seborrheic Dermatitis

Seborrheic Dermatitis

United States
Arcutis Biotherapeutics, Inc.

Completed

Open Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-OLE)

Atopic Dermatitis Eczema

United States, Canada
National Institute on Aging (NIA)

Completed

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

Healthy Volunteers

United States
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (Integument-PED)

Atopic Dermatitis Eczema

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast (ARQ-154) Foam 0.3% for the Management of Seborrheic Dermatitis (STRATUM)

Seborrheic Dermatitis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis (DERMIS-OLE)

Chronic Plaque Psoriasis

United States, Canada, Dominican Republic
The University of Texas Health Science Center at...

Withdrawn

Clinical Trial of Roflumilast Added to Standard Chemoimmunotherapy

Lymphoma, B-Cell

United States
The University of Texas Health Science Center at...

Completed

Study of Roflumilast in Combination With Standard Chemotherapy for High-risk Diffuse Large B-cell Lymphoma

Lymphoma, B-Cell

United States
Maastricht University
Netherlands Brain Foundation

Completed

Roflumilast to Treat Cognitive Sequela After Stroke (ROSTMEMA)

Cerebrovascular Disorders | Functional Recovery | Memory | Drug Intervention

Netherlands
Arcutis Biotherapeutics, Inc.

Completed

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-215)

Psoriasis | Plaque Psoriasis

United States, Canada, Dominican Republic
Tanta University

Completed

Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy

Diabetic Neuropathies | Type 2 Diabetes (Adult Onset)

Egypt
University of California, Davis

Terminated

Phosphodiesterase 4 Inhibitor, Roflumilast, and the Effects of Inhibition in Severe Asthma

Asthma

United States
AstraZeneca

Completed

Long-term Observational Study of the Safety of Roflumilast

COPD

Sweden, Germany, United States, Norway
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-II)

Atopic Dermatitis Eczema

United States, Canada
Padagis LLC

Completed

Bioequivalence Study of Two Treatments for the Treatment of Plaque Psoriasis

Plaque Psoriasis

United States
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-I)

Atopic Dermatitis Eczema

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Safety and Efficacy of ARQ-154 Foam in Subjects With Seborrheic Dermatitis

Seborrheic Dermatitis

United States, Canada
Bispebjerg Hospital

Completed

Efficacy of Roflumilast in the Treatment of Psoriasis (PSORRO)

Psoriasis

Denmark
Dermatology Consulting Services, PLLC

Completed

Evaluation of the Safety and Efficacy of Topical Roflumilast Cream in the Treatment of Facial Papulopustular Rosacea

Rosacea

United States
Cairo University

Completed

Roflumilast Versus Methotrexate in Psoriasis

Psoriasis

Egypt
Arcutis Biotherapeutics, Inc.

Completed

Topical Roflumilast to Treat Scalp and Body Psoriasis (ARRECTOR) (ARRECTOR)

Scalp Psoriasis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-216)

Psoriasis | Plaque Psoriasis

United States, Canada, Dominican Republic
Arcutis Biotherapeutics, Inc.

Completed

Safety and Efficacy of ARQ-151 Cream in Adolescents and Adults With Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Twin Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis (DERMIS-2)

Chronic Plaque Psoriasis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis (DERMIS-1)

Chronic Plaque Psoriasis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Safety and Efficacy of ARQ-154 Foam in Adolescent and Adult Subjects With Scalp and Body Psoriasis

Plaque Psoriasis

United States, Australia, Bulgaria, Canada
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); American Lung Association

Completed

Trial of Roflumilast in Asthma Management (TRIM) (TRIM)

Obesity | Asthma

United States
Arcutis Biotherapeutics, Inc.

Completed

Long-Term Safety of ARQ-151 Cream in Adult Subjects With Chronic Plaque Psoriasis

Plaque Psoriasis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

The Safety, Efficacy and Pharmacokinetics of ARQ-151 Cream in Subjects With Chronic Plaque Psoriasis (ARQ-151-201)

Plaque Psoriasis

United States, Canada
Tanta University

Completed

The Possible Effects of Roflumilast on Obesity Related Disorders

Obesity | PreDiabetes

Egypt
Cairo University

Completed

Roflumilast as add-on Therapy in Early Cases of ARDS

Respiratory Distress Syndrome, Adult

Egypt
University of Calgary

Withdrawn

Roflumilast TMS-EEG Plasticity

Synaptic Plasticity

Canada
Tanta University

Unknown

Possible Role of Roflumilast in Diabetic Nephropathy

Diabetic Nephropathies
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome

Nervous System Disease

United States
Temple University
Forest Laboratories

Completed

Effects of Roflumilast in Hospitalized Chronic Obstructive Pulmonary Disease( COPD) on Mortality and Re-hospitalization

COPD

United States
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Effect of Roflumilast on Quality of Life, Lung Function and Mucus Properties in Patients With Bronchiectasis

Bronchiectasis Adult

Brazil
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Roflumilast and Cognition (EEGrofl)

Dementia

Netherlands
AstraZeneca

Completed

Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD

Poland, United Kingdom, Germany, Sweden, Denmark

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