Search clinical trials for: [14C] NKTR-118

Total 4264 results

Mahidol University

Completed

Comparison of Lactated Ringer's Solution and PlasmaLyte-A as a Base Solution for Del Nido Cardioplegia

Myocardial Injury

Thailand
Massachusetts General Hospital

Completed

PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients

Sciatica

United States
Centre for Addiction and Mental Health

Completed

MAO-B Occupancy in Depressed Patients (MOCP)

Major Depressive Disorder | Treatment Resistant Depression

Canada
Janssen Research & Development, LLC

Completed

A Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand 11C-MK-3168 and the Blocking of the Retention of the Ligand in the Human Brain by JNJ-42165279

Healthy

Belgium
Stempeutics Research Pvt Ltd

Completed

Mesenchymal Stem Cells in Critical Limb Ischemia

Critical Limb Ischemia

India
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome

Nervous System Disease

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Investigate the Absorption, Metabolism, and Excretion of Canagliflozin (JNJ-28431754) in Healthy Male Volunteers

Healthy

Belgium
University Hospital, Montpellier

Recruiting

Prediction of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage Using Dynamic 18F-FDG PET/CT (PREDISP)

Aneurysmal Subarachnoid Haemorrhage

France
Pfizer

Completed

A Study To Asses Mass Balance And Absolute Bioavailability Of 14C PF-06826647 In Healthy Male Participants

Healthy

Netherlands
Alexion Pharmaceuticals

Completed

Study of Radiolabeled ALXN2050 in Healthy Adult Males

Healthy

United States
Hutchmed

Active, not recruiting

Human Mass Balance of [14C]HMPL-523 in Healthy Adult Male Chinese Subjects

Imumune Thrombocytopenia(ITP) Human Mass Balance

China
IRCCS San Raffaele

Completed

PET Study of Acetylcholine Esterase Activity in Alzheimer's Disease

Alzheimer Disease
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis

Diabetes | Gastroparesis With Diabetes Mellitus

United States
St. Jude Children's Research Hospital

Active, not recruiting

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

Ependymoma

United States, Canada
Merck Sharp & Dohme LLC

Completed

Positron Emission Tomography/Computed Tomography (PET/CT) in Relapsed Ovarian Cancer (MK-0000-143)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer
Rhythm Pharmaceuticals, Inc.

Recruiting

A Study of RM-718 in Healthy Subjects and in Patients With HO

Hypothalamic Obesity

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]BMS-986419 in Healthy Male Participants

Healthy Volunteers

United States
Seoul National University Hospital

Unknown

To Investigate the Absorption, Metabolism, Excretion, Absolute Bioavailability, and Immunogenicity of GX-I7 in Healthy Volunteers

Leukopenia

Korea, Republic of
Seoul National University Hospital

Completed

Absolute Bioavailability of YH4808 With Accelerator Mass Spectrometry(AMS)-Based Microdose Study

Gastroesophageal Reflux Disease

Korea, Republic of
Galapagos NV

Completed

Investigation of the Pharmacokinetics and Metabolism of GLPG0634 in Healthy Male Subjects

Healthy

United Kingdom
Amgen

Completed

A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy Participants

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Bristol-Myers Squibb

Completed

Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986278 in Healthy Male Participants

Healthy Volunteers

United States
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Open-label Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of a Single Oral Dose of [14C]-20 mg/100 μCi Anaprazole Sodium Enteric-coated Capsule in Healthy Adult Male Subjects

Healthy Male Volunteers
Universitaire Ziekenhuizen KU Leuven

Completed

Synaptic Density and Progression of Parkinson's Disease.

Parkinson Disease

Belgium
University of California, Davis

Not yet recruiting

Zinc and Iron Absorption From Common Beans in Young Adult Women

Iron Absorption | Zinc Absorption

United States
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of 5% Albumin v/s Plasmalyte in Combination With 20% Albumin for Fluid Resuscitation in Cirrhosis With Sepsis Induced Hypotension

Liver Cirrhosis

India
BioCardia, Inc.

Not yet recruiting

AllogeneiC Expanded Human MSC Therapy in Patients Recovering From COVID-19 Acute Respiratory Distress Trial (ACE_CARD)

ARDS, Human
Galderma R&D

Completed

Systemic Bioavailability Study Of Col-118 Administered Topically as a 0.18 % Facial Gel And Brimonidine Ophthalmic Solution 0.2%

Erythematous Rosacea

United States
Minerva Neurosciences

Completed

A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive Disorder

Major Depressive Disorder

United States, Bulgaria, Finland, Georgia, Moldova, Republic of, Poland, Ukraine
Sensorion

Completed

Efficacy of SENS-111 in Patients Suffering From Acute Unilateral Vestibulopathy

Acute Unilateral Vestibulopathy (AUV)

United States, Israel, France, Korea, Republic of, Hungary, Germany, Czechia, Italy
Erasme University Hospital

Unknown

Correlation Between Duration of Fasting and Response to Fluid Replenishment, Evaluated With Repeated Measures of VTI.

Fluid Therapy | Fluid and Electrolyte Imbalance

Belgium
University of Liege

Completed

HES and Acute Kidney Injury in Adult Cardiac Surgery

Acute Kidney Injury After Adult Cardiac Surgery
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Test How the Test Medicine GLPG1972 is Taken up by the Body When Given by Mouth and Into the Vein as an Injection

Healthy

United Kingdom
Nektar Therapeutics

Terminated

A Study of NKTR-262 in Combination With Bempegaldesleukin (NKTR-214) and With Bempegaldesleukin Plus Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumor Malignancies (REVEAL)

Melanoma | Sarcoma | Renal Cell Carcinoma | Colorectal Cancer | Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Merkel Cell Carcinoma

United States
Lawrence Recht
Nektar Therapeutics

Completed

Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma

Anaplastic Astrocytomas | Glioblastomas (GBM) | Anaplastic Oligodendrogliomas

United States
PainReform LTD

Completed

A Safety and Effectiveness Pilot Study of PRF-108 and PRF-110 in Healthy Volunteers

Pain

Israel
Millennium Pharmaceuticals, Inc.

Completed

Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants

Healthy Volunteers

United States
Bristol-Myers Squibb

Withdrawn

A Study of Absorption, Metabolism, and Elimination CC-90010 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Spain
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid

Bacterial Infections | Inflammatory Disease | Renal Excretion | Oncologic Disease

United States
UCB Pharma

Terminated

A 12 Week Study to Assess Changes in Joint Inflammation Using Ultrasonography in Patients With Rheumatoid Arthritis (RA) (SWIFT)

Rheumatoid Arthritis

United States
University of California, Davis
National Cancer Institute (NCI)

Completed

Oxaliplatin in Treating Patients With Metastatic Breast Cancer

Stage IV Breast Cancer

United States
Pfizer

Completed

A Study to Learn About Effect of Sisunatovir in Healthy Adult Male Participants

Respiratory Syncytial Virus Infections

United States
Teva Branded Pharmaceutical Products R&D, Inc.
Covance

Terminated

A Study to Investigate the Absorption, Metabolism and Excretion of Talampanel

Healthy

United States
Bayer

Completed

A Study to Learn How BAY2927088 is Taken up and Handled by the Body in Healthy Male Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

Netherlands
Debiopharm International SA

Completed

Mass Balance Recovery and Metabolic Profile of 14C Debio 1450 Following Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy

United Kingdom
Bristol-Myers Squibb
Nektar Therapeutics

Completed

A Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic Melanoma

Melanoma

Canada, Australia, France, Italy, Brazil, United States, Argentina, Austria, Belgium, Chile, Czechia, Finland, Germany, Greece, Ireland, Israel, Mexico, Netherlands, New Zealand, Poland, Portugal, Romania, Russian Federation, Spain, Sweden and more
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd; Nektar Therapeutics

Completed

An Investigational Study of NKTR-214 Combined With Nivolumab in Japanese Participants With Advanced Solid Tumors

Advanced Cancer

Japan
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

Cardiovascular Disease

United Kingdom
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers

Healthy
Stempeutics Research Pvt Ltd
Stempeutics Research Malaysia SDN BHD

Completed

Allogeneic Mesenchymal Stem Cells for Osteoarthritis

Osteoarthritis of Knee Joint

Malaysia

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