Search clinical trials for: Histamine H3 Antagonists

Total 33027 results

Wayne State University

Completed

Role of Mirtazapine in Ameliorating Sleep Disordered Breathing

Sleep Disordered Breathing | Spinal Cord Injuries
Merck Sharp & Dohme LLC

Completed

A Long-Term Safety Study of Org 50081 (Esmirtazapine) in Elderly Outpatients With Chronic Primary Insomnia (176005/P05697/MK-8265-001) (Jade)

Dyssomnias | Sleep Disorders | Mental Disorder | Sleep Initiation and Maintenance Disorder; Elderly | Sleep Disorder, Intrinsic
Merck Sharp & Dohme LLC

Completed

A 6-Month Efficacy and Safety Study of Org 50081 in Adult Patients With Chronic Primary Insomnia (21106/P05701/MK-8265-002)

Mental Disorders | Dyssomnias | Sleep Initiation and Maintenance Disorders | Sleep Disorders | Sleep Disorder, Intrinsic
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From Depression

Depression | Cocaine Dependence

United States
Brasilia University Hospital

Unknown

Mirtazapine for Sleep Disorders in Alzheimer's Disease

Alzheimer's Disease | Sleep Disorders

Brazil
The University of Texas Health Science Center,...
Society of Cardiovascular Anesthesiologists

Recruiting

Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor

Acute Kidney Injury

United States
Amgen

Completed

A Study to Evaluate the Impact of Acid-reducing Agents on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants

Healthy Participants

United States
Vanderbilt University

Withdrawn

Refractory Eustachian Tube Dysfunction: Are the Symptoms Related to Endolymphatic Hydrops

Endolymphatic Hydrops | Eustachian Tube Dysfunction

United States
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Reflux Oesophagitis

United Kingdom
Vistakon Pharmaceuticals

Completed

Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Pamukkale University

Completed

Comparison of Efficacy Dimenhydrinate and Metoclopramide in the Treatment of Nausea Due to Vertigo

Nausea | Vomiting | Vertigo
Merck Sharp & Dohme LLC

Terminated

Twenty-six Week Extension Trial of Org 50081 (Esmirtazapine) in Outpatients With Chronic Primary Insomnia (176003/P05721/MK-8265-007)

Mental Disorders | Sleep Disorders, Intrinsic | Dyssomnias | Sleep Initiation and Maintenance Disorders | Sleep Disorders
Merck Sharp & Dohme LLC

Completed

Fifty Two Week Extension Trial of Org 50081 (Esmirtazapine) in the Treatment of Insomnia (P05708)

Insomnia
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)

Mental Disorders | Dyssomnias | Insomnia | Sleep Initiation and Maintenance Disorders | Sleep Disorders
Boston University

Completed

Efficacy of Mirtazapine in Depressed Cocaine Dependent Subjects

Depression | Cocaine Dependence

United States
Samsung Medical Center

Unknown

Pharmacogenetic Study of Mirtazapine Response in Depressed Patients

Depression

Korea, Republic of
Mahidol University
University of Texas; University of Wuerzburg

Completed

Study of Indoleamine 2,3-dioxygenase Activity, Serum Levels of Cytokines, BDNF, BH4 and Mirtazapine Efficacy in Fibromyalgia Syndrome

Fibromyalgia Syndrome

Thailand
Universitaire Ziekenhuizen KU Leuven

Unknown

Mirtazapine Versus Placebo in Functional Dyspepsia

Functional Dyspepsia

Belgium
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions

Healthy

Canada
Apsen Farmaceutica S.A.

Completed

Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin

Vertigo, Peripheral

Brazil
The Hospital for Sick Children
Duchesnay Inc.

Completed

Pre-emptive Treatment of Severe Nausea and Vomiting of Pregnancy

Pregnancy | Hyperemesis Gravidarum

Canada
Vistakon Pharmaceuticals

Completed

Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers

Allergic Conjunctivitis

United States
Community Research Initiative of New England

Completed

A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection

HIV Infections

United States
Johnson & Johnson Consumer and Personal Products...

Completed

To Determine if Diphenhydramine Works for Nasal Congestion at Two Different Doses

Nasal Congestion

United States
Kinnov Therapeutics
ECSOR

Completed

Clinical Outcome of a Patented Pharmaceutical Composition (KT-110) to Treat Alcohol Use Disorder While Avoiding Major Side Effects (COCKTAIL)

Alcohol Use Disorder

France
Stanford University

Completed

Palonosetron and Hydroxyzine to Reduce Opioid Withdrawal

Substance-Related Disorders

United States
University of Chicago

Recruiting

A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection (COVID-19)

COVID-19

United States
Sandoz

Completed

Efficacy and Safety of Azelastine +Mometasone , Nasal Spray, 140 mcg + 50 mcg, (Sandoz d.d., Slovenia) and Momat Rino Advance, Nasal Spray, 140 mcg + 50 mcg, (Glenmark, India) Administered as a Monotherapy to Patients With Seasonal Allergic Rhinitis.

Seasonal Allergic Rhinitis

Russian Federation
Sandoz

Completed

Prospective, Randomized, Multinational, Multicenter, Double-blind, Placebo and Active Controlled Trial in 4 Parallel-groups of Patients Suffering From Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Bulgaria, Germany, Poland, Moldova, Republic of
Alcon Research

Completed

Safety Study of Olopatadine Nasal Spray

Perennial Allergic Rhinitis

United States
Hanmi Pharmaceutical Company Limited

Completed

Efficacy/Safety of Pseudoephedrine Plus Levocetirizine Versus Placebo in Patients With Vasomotor Rhinitis

Vasomotor Rhinitis

Korea, Republic of
Meda Pharmaceuticals

Completed

A Study to Evaluate the Safety & Effectiveness of a Nasal Spray to Treat Seasonal Allergies

Seasonal Allergic Rhinitis

United States
Meda Pharmaceuticals

Completed

Study to Evaluate the Safety and Tolerability of a Nasal Spray in Patients With Chronic Allergic or Nonallergic Rhinitis

Chronic Allergic Rhinitis | Nonallergic Rhinitis

United States
Sandoz

Terminated

Study to Compare the Pharmacokinetics of Fixed-Dose Combination of Mometasone + Azelastine Nasal Spray to Mometasone and Azelastine Nasal Sprays in Adolescents and Young Adults With Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Sandoz

Completed

To Demonstrate the Relative Bioavailability Study of Loratadine 10 mg Tablets

Allergy
GlaxoSmithKline

Completed

Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine

Rhinitis, Allergic, Seasonal

United States
Peking Union Medical College Hospital

Unknown

Effectiveness of Qufeng Shengshi Fang on Treatment of Allergic Rhinitis.

Rhinitis, Allergic, Perennial

China
Meda Pharmaceuticals

Completed

A Study to Evaluate the Safety and Tolerability of a Nasal Spray to Treat Perennial Allergic Rhinitis

Perennial Allergic Rhinitis

United States
EMS

Completed

Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Persistent Allergic Rhinitis Treatment

Allergic Rhinitis
EMS

Unknown

Comparison of Desloratadine Associated With Prednisolone (Tablet)Versus Dexchlorpheniramine Associated With Betamethasone (Tablet) for Adult Persistent Allergic Rhinitis Treatment

Allergic Rhinitis

Brazil
University of Maryland, Baltimore

Completed

HCV Treatment Immune Response With Grazoprevir/Elbasvir Before or After Renal Transplant

Renal Insufficiency, Chronic | Hepatitis C | Disorder of Transplanted Kidney

United States
EMS

Terminated

Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Cutaneous Rash Treatment

Cutaneous Hypersensitivity

Brazil
Campus Bio-Medico University

Completed

Aprepitant in the Management of Biological Therapies-related Severe Pruritus (AprepIt)

ITCH

Italy
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Recruiting

CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy

Multiple Sclerosis

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects

Healthy Subjects

Germany
Arrowhead Pharmaceuticals
ICON Clinical Research

Terminated

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Hong Kong
University of California, San Francisco
National Institute of General Medical Sciences (NIGMS)

Completed

Drug-Drug Interaction Study With Metformin and Nizatidine

Healthy

United States
RSPR Pharma AB

Completed

Study in Healthy Volunteers to Document Safety and Tolerability of Increasing Doses Pemirolast

Healthy Volunteers
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, Food, Formulation, and pH Effects on Relative Absorption of BMS-986465 and Its Active Derivative BMS-986464 in Healthy Participants

Healthy Participants

United States
Oriental Neurosurgery Evidence-Based-Study Team

Recruiting

To Evaluate the Therapeutic Efficacy of Hydrated Amniotic Membrane in Promoting Closure of Refractory Macular Holes.

Macular Holes

China

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