Clinical Trials Sponsored by Duke Cancer Institute

Total 29404 results

Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Behavioral Factors in Coronary Heart Disease

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Metabolic Syndrome X
Johns Hopkins University
Duke University; Maryland Medical Research Institute

Completed

Randomized Comparison Angioplasty Outcomes at Hospitals With and Without On-site Cardiac Surgery

Angina Pectoris | Coronary Arteriosclerosis

United States
Vertex Pharmaceuticals Incorporated
Duke Clinical Research Institute; ViroChem Pharma

Completed

Safety,Tolerability and Pharmacokinetics of Multiple Ascending Doses of VCH 916 in Subjects With Chronic Hep C Infection

HCV Infection

Puerto Rico, United States, Canada
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Resistance and Aerobic Exercise on Cardiovascular Health (STRRIDE2)

Heart Diseases | Cardiovascular Diseases | Obesity | Insulin Resistance | Hyperlipidemia | Metabolic Syndrome X

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Umbilical Cord Blood Stem Cell Transplantation in Adults With Advanced Blood Disorders or Cancer

Hematologic Neoplasms

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM))

Long COVID | Long Covid19 | Long Covid-19
Duke University
University of Pennsylvania; National Eye Institute (NEI)

Recruiting

Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2) (BabySTEPS2)

Retinopathy of Prematurity

United States
University of California, San Francisco
Duke Clinical Research Institute

Completed

Facilitating COVID-19 Test for Korean Americans Through Korean Schools in Northern California

Educational Activities

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Exercise, Heart Failure, and Type 2 Diabetes

Heart Failure | Type 2 Diabetes

United States
Duke University
National Institute of General Medical Sciences (NIGMS)

Completed

Delivery of Pharmacogenetic Testing in a Community Pharmacy Setting

Pharmacogenetics

United States
Janssen Scientific Affairs, LLC
Bayer; Duke Clinical Research Institute

Completed

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II) (ORBIT-AF II)

Atrial Fibrillation

United States, Puerto Rico, Virgin Islands (U.S.)
AegisCN LLC
Duke Clinical Research Institute; PharPoint Research, Inc.

Completed

A Proof of Concept Study to Evaluate CN-105 in ICH Patients (CATCH)

Intracerebral Hemorrhage

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease (STICH)

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Heart Failure, Congestive

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stress Management and Biomarkers of Risk in Cardiac Rehabilitation (ENHANCED)

Coronary Heart Disease

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Guiding Evidence Based Therapy Using Biomarker Intensified Treatment (GUIDE-IT)

Heart Failure

United States, Canada
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cell Phone Intervention in Young Adults (CITY)

Obesity

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure (ATHENA-HF)

Heart Failure

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Coping Skills and Heart Failure: Outcomes and Mechanisms (COPE-HF)

Heart Failure

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) (FIGHT)

Acute Heart Failure

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Teen CHAT: Improving Physician Communication With Adolescents About Healthy Weight (TeenCHAT)

Obesity | Physical Activity | Sleep | Communication | Nutrition

United States
Duke University
North Carolina Translational and Clinical Sciences Institute

Withdrawn

Cortical Metrics in Intervention Trials With Autism Spectrum Disorders

Autism Spectrum Disorders

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness of Bridging Anticoagulation for Surgery (The BRIDGE Study)

Atrial Fibrillation | Arterial Thromboembolic Events

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

PROspective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE)

Chest Pain

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT)

Myocardial Ischemia

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol (RESULT)

Gastroesophageal Reflux Disease (GERD) | Reflux

United States, Canada
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study (ROSE/RED ROSE)

Acute Heart Failure

United States, Canada
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Coping Skills for Patients With Chronic Obstructive Pulmonary Disease (COPD) and Their Caregivers

Chronic Obstructive Pulmonary Disease

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Investigational Study of Psychological Intervention in Recipients of Lung Transplant (INSPIRE) (INSPIRE)

Depression | Lung Diseases
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

ENCORE: Exercise and Nutritional Interventions for Cardiovascular Health (ENCORE)

Hypertension

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Exercise Training Program to Improve Clinical Outcomes in Individuals With Congestive Heart Failure

Heart Diseases | Cardiovascular Diseases | Heart Failure, Congestive

United States, Canada, France
Mayo Clinic
Abbott Medical Devices; Duke Clinical Research Institute

Completed

Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial (CABANA)

Atrial Fibrillation | Arrhythmia

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Understanding of Genetic Risk Information for Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Weight Loss Maintenance (WLM) (WLM)

Heart Diseases | Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus, Non-insulin Dependent
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Recruiting

An Escape Room Intervention to Help Improve Breast Cancer Patients' Ability to Navigate Online Access to Nutrition Information

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Recruiting

A Combined Biomarker Model for Risk Stratification of Indeterminate Pulmonary Nodules

Pulmonary Nodule

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Recruiting

Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors

Stage III Colorectal Cancer AJCC v8 | Stage II Colorectal Cancer AJCC v8

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients

Glioma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

A Phase 1b Study of Gemcitabine and Nab-paclitaxel in Combination With IM156 in Patients With Advanced Pancreatic Cancer.

Pancreas Cancer

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Association Between Gut Microbiome and Dietary Determinants and Vaccine Response

Influenza

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Mobile-Health Delivery of Lifestyle Interventions for Women With Breast Cancer

Breast Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Quality of Life and Function of Patients With Pelvic Tumors After Undergoing Hemipelvectomy

Malignant Primary Pelvic Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling

Li-Fraumeni Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | BK Virus Infection | Symptomatic COVID-19 Infection Laboratory-Confirmed | Adenovirus Infection | Cytomegaloviral Infection | JC Virus Infection

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis

Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Promoting HPV Vaccination Among Young Adults in Texas

HPV | Related Malignancy | Related Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Patient-Specific Computational Walking Models in Improving Surgical and Rehabilitation Treatment in Patients With Pelvic Sarcomas

Pelvic Sarcoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Increasing Access to Smoking Cessation and Smoke Free Home Services for Low-Income Pregnant Women in Northeast Texas

Cigarette Smoking-Related Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Engineered NK Cells Containing Deleted TGF-BetaR2 and NR3C1 for the Treatment of Recurrent Glioblastoma

Recurrent Gliosarcoma | Recurrent Supratentorial Glioblastoma | Supratentorial Gliosarcoma

United States

Clinical Trials Sponsored by Duke Cancer Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Moldova

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Rare Diseases

Drug Interventions

Dietary Supplements

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