Clinical Trials Sponsored by Merck Sharp & Dohme LLC

Total 3962 results

Merck Sharp & Dohme LLC

Completed

MK0557 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0557-027)

Schizophrenia | Paranoid Schizophrenia
Merck Sharp & Dohme LLC

Completed

Comparing 4.0 mg.Kg-1 Sugammadex With Placebo in the Reversal of Profound Neuromuscular Blockade (P05767)

Anesthesia | Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

An Observational Study of Fungal Biomarkers (MK-0000-089)

Aspergillosis
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Safety and Tolerability of MK-0517 in Healthy Subjects (MK-0517-012)

Postoperative Nausea and Vomiting | Chemotherapy-Induced Nausea and Vomiting
Merck Sharp & Dohme LLC

Completed

Evaluation of Continuous Glucose Monitoring in Participants With Type 2 Diabetes Mellitus (MK-0000-258 AM2)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED)

Type 2 Diabetes
Merck Sharp & Dohme LLC

Completed

A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED)

Liver Insufficiency
Merck Sharp & Dohme LLC

Completed

Study of the Bioequivalence of Two Tablet Forms of MK0431 (0431-027)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

A Study to Examine the Safety and Tolerability of MK0517 for the Prevention of Post-Operative Nausea and Vomiting (0517-015)

Post-Operative Nausea and Vomiting
Merck Sharp & Dohme LLC

Completed

Lipid Management in Clinical Practice (MK-0524A-115)

Lipid Metabolism Disorder
Merck Sharp & Dohme LLC

Completed

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)

Postoperative Pain
Merck Sharp & Dohme LLC

Completed

MK0249 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0249-016)

Paranoid Schizophrenia
Merck Sharp & Dohme LLC

Completed

A Study to Test the Safety and Efficacy of MK0249 in Patients With ADHD (0249-018)(COMPLETED)

Attention-Deficit/Hyperactivity Disorder (ADHD)
Merck Sharp & Dohme LLC

Completed

Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED)

Alzheimer's Disease
Merck Sharp & Dohme LLC

Completed

Study of Biomarkers of Airway Inflammation (0000-128)

Airway Inflammation
Merck Sharp & Dohme LLC

Completed

V710 First-In-Man (FIM) Study (V710-001)

Staphylococcal Infections
Merck Sharp & Dohme LLC

Withdrawn

A Single-Dose Study of MK-8351 in a Lung Allergen Challenge (MK-8351-003)

Asthma
Merck Sharp & Dohme LLC

Terminated

Safety Study of CAELYX in Patients With Metastatic Breast Cancer Previously Treated With Anthracyclines (Study P04057)(TERMINATED)

Breast Neoplasm
Merck Sharp & Dohme LLC

Completed

A Study of Absorption, Metabolism, Excretion and Mass Balance After a Single Dose Administration of MK-0941 (MK-0941-016)(COMPLETED)

Type 2 Diabetes
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of MK0974 in the Acute Migraine (0974-016)

Migraine
Merck Sharp & Dohme LLC

Completed

Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC

Terminated

ATHENAS - Retrospective Study of Compliance in Chronic Hepatitis C With Pegylated Interferon Alfa-2b/Ribavirin in Brazil (P05632) (ATHENAS)

Hepatitis C, Chronic
Merck Sharp & Dohme LLC

Completed

Effect of Insulin Resistance on the Safety and Efficacy of Pegylated Interferon and Ribavirin Treatment in HCV (Study P05562)

Hepatitis C, Chronic | Hepatitis C Virus
Merck Sharp & Dohme LLC

Completed

Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED)

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Terminated

Remicade® Crohn's Disease Registry Across Canada (Study P02793) (RemiTRAC®)

Crohn's Disease
Merck Sharp & Dohme LLC

Withdrawn

Broad Spectrum HPV Vaccine Tolerability, Immunogenicity, and Efficacy Study (V502-003)

Cervical Cancer | Condylomata Acuminata
Merck Sharp & Dohme LLC

Terminated

Placebo Controlled Metformin and Sulfonylurea Combination Study in Patients With Type 2 Diabetes (0767-025)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC

Completed

A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

MK0431 Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-040)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Terminated

Study MK0767 and Metformin in Type 2 Diabetic Patients (0767-020)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC

Completed

MK0782 + Low-Dose Aspirin 7-Day Erosion Endoscopy Study (0782-001)

Duodenal Ulcer | Stomach Ulcer
Merck Sharp & Dohme LLC

Completed

A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095)

Type 2 Diabetes
Merck Sharp & Dohme LLC

Terminated

Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)

Hyperlipoproteinemia Type II | Homozygous Familial Hypercholesterolemia
Merck Sharp & Dohme LLC

Withdrawn

A Study of Immune Cells in Patients With Rheumatoid Arthritis During Different Types of Anti-TNF Alpha Treatments (Study P05521)

Rheumatoid Arthritis
Merck Sharp & Dohme LLC

Completed

A Study That Will Evaluate Ketogenesis and Glucose-Dependent Insulin Secretion Methodologies in Healthy Male Subjects (MK-0000-159)(COMPLETED)

Obesity
Merck Sharp & Dohme LLC

Terminated

A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013)

Myelodysplastic Syndromes | Chronic Lymphocytic Leukemia | Leukemia, Lymphoblastic, Acute, T-cell | Myelogenous Leukemia
Merck Sharp & Dohme LLC

Completed

A Study of MK0359 in Patients With Chronic Asthma (0359-013)

Asthma
Merck Sharp & Dohme LLC

Completed

Biomarkers of Prednisolone Treatment (P05888)

Hyperglycemia | Insulin Resistance | Glucose Intolerance
Merck Sharp & Dohme LLC

Terminated

Safety and Preliminary Efficacy of MK0759 in Postherpetic Neuralgia (PHN)(0759-004)

Neuralgia, Postherpetic
Merck Sharp & Dohme LLC

Completed

Phase 1 Study of Vorinostat and Bortezomib in Multiple Myeloma (MK-0683-015 EXT 1 (AM1))

Multiple Myeloma
Merck Sharp & Dohme LLC

Completed

Neuropathic Pain Syndrome Patient Study (MK-0000-072)

Diabetic Neuropathy | Neuralgia, Postherpetic | Painful Small-Fiber Neuropathy | Idiopathic Distal Sensory Polyneuropathy
Merck Sharp & Dohme LLC

Terminated

Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED)

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic | Myelodysplasia | Myelomonocytic
Merck Sharp & Dohme LLC

Completed

Evaluation of Satisfaction in Patients Receiving PegIntron Pen/Rebetol for Hepatitis C (Study P04067) (SATISFACTION)

Hepatitis C, Chronic
Merck Sharp & Dohme LLC

Completed

To Study Different Levels of MK0493 for Safety, Efficacy, and Tolerability in Obese Patients (0493-017)(COMPLETED)

Obesity
Merck Sharp & Dohme LLC

Completed

MK0429 Study in Prostate Cancer Patients With Metastatic Bone Disease (0429-011)

Prostatic Neoplasms
Merck Sharp & Dohme LLC

Completed

Study of Hepatitis C Virus (HCV) Nonstructural Protein 5a (NS5A) Inhibitor IDX719 in Healthy and HCV-Infected Participants (MK-1894-001)

Hepatitis C, Chronic
Merck Sharp & Dohme LLC

Withdrawn

Safety and Efficacy Study of an Etoricoxib and Tizanidine Fixed Dose Combination in Participants With Moderate to Severe Acute Low Back Pain (MK-0663B-164)

Low Back Pain
Merck Sharp & Dohme LLC

Terminated

An Investigational Study of a Histone Deacetylase (HDAC) Inhibitor Plus Targretin in Cutaneous T-Cell Lymphoma Patients (0683-016)(TERMINATED)

Lymphoma
Merck Sharp & Dohme LLC

Terminated

A Study of Carboplatin + Paclitaxel and MK0683 in Patients With Chemotherapy-naive Non-Small Cell Lung Cancer (NSCLC)(0683-066)

Neoplasms
Merck Sharp & Dohme LLC

Completed

Effects of Andriol Testocaps in Symptomatic Late-Onset Hypogonadism (43203)

Hypogonadism | Androgens

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