Clinical Trials Sponsored by aTyr Pharma, Inc.

Total 2355 results

Zurex Pharma, Inc.

Completed

Perioperative Patient Skin Antiseptic Preparation Evaluation

Surgical Site Infection

United States
MEI Pharma, Inc.

Terminated

Zandelisib (ME-401) in Subjects With Follicular Lymphoma or Marginal Zone Lymphoma After Failure of Two or More Prior Therapies (TIDAL)

Marginal Zone Lymphoma | Non Hodgkin Lymphoma | Follicular Lymphoma (FL)

United States, Spain, Korea, Republic of, Belgium, Taiwan, Germany, France, Italy, Australia, Poland, New Zealand, United Kingdom, Austria, Switzerland
OBI Pharma, Inc

Terminated

Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors

Locally Advanced Solid Tumor

United States
Vincerx Pharma, Inc.

Terminated

A Study to Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome

Chronic Lymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Relapsed Non Hodgkin Lymphoma | Richter Syndrome | MYC Amplification | MYC Overexpression | MYC Translocation

United States, Poland
Astellas Pharma Inc

Completed

A Study for Ureter Visualization, Using ASP5354 in Subjects Undergoing Laparoscopic/Minimally Invasive Colorectal Surgery

Laparoscopic/Minimally Invasive Colorectal Surgery

United States
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis

Mydriasis | Dilation

United States
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision Disturbances

Dim Light Vision Disturbances

United States
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3) (MIRA-3)

Mydriasis | Dilation

United States
Klus Pharma Inc.

Completed

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Cervical Cancer | Head and Neck Cancer | Mucoepidermoid Carcinoma | Pancreatic Cancer | Recurrent Prostate Cancer | Lung Cancer | Rectal Cancer | Solid Tumor | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Recurrent Ovarian Carcinoma | Bladder Cancer | Skin Cancer | HER2-positive Breast Cancer | Rare Diseases | Colo-rectal Cancer and other conditions

United States
CinCor Pharma, Inc.

Completed

A Study of CIN-107 in Patients With Uncontrolled Hypertension (HALO)

Uncontrolled Hypertension

United States
Sinew Pharma Inc.

Completed

A Randomized, Single-blind, Parallel Group and Multiple - Dose Design Study

Acetaminophen Toxicity

Taiwan
Astellas Pharma Inc

Completed

Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery

Acute Kidney Injury (AKI)

United States
Acasti Pharma Inc.

Active, not recruiting

Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects

Postherpetic Neuralgia

Canada
InnoCare Pharma Inc.

Active, not recruiting

Evaluate the Safety, Tolerability, and Pharmacokinetics of ICP-723 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
NS Pharma, Inc.

Active, not recruiting

Long-term Use of Viltolarsen in Boys With Duchenne Muscular Dystrophy in Clinical Practice (VILT-502)

Duchenne Muscular Dystrophy

United States, Canada
Astellas Pharma Inc

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ASP5354 in Healthy Adult Japanese Male Participants

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate the Effect of ASP7991 in Secondary Hyperparathyroidism Patients Undergoing Hemodialysis

Secondary Hyperparathyroidism

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate Long-term Safety and Efficacy of ASP1941 in Diabetes Patients

Type 2 Diabetes Mellitus

Japan
Amarin Pharma Inc.

Completed

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (MARINE)

Hypertriglyceridemia

United States, Netherlands, Russian Federation, Ukraine, Denmark, Finland, Germany, India, Italy, Mexico, South Africa
Amarin Pharma Inc.

Completed

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (ANCHOR)

Hypertriglyceridemia

United States
Amarin Pharma Inc.

Completed

A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin (REDUCE-IT)

Cardiovascular Diseases

United States, Australia, Canada, India, Netherlands, New Zealand, Poland, Romania, Russian Federation, South Africa, Ukraine
NS Pharma, Inc.

Completed

Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States
Astellas Pharma Inc

Completed

Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases)

Irritable Bowel Syndrome With Constipation (IBS-C) | Chronic Constipation (CC) (Excluding Constipation Due to Organic Diseases)

Japan
Sinew Pharma Inc.

Completed

A Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of SNP-630 in Health Subjects.

NASH - Nonalcoholic Steatohepatitis

Taiwan
CinDome Pharma, Inc.

Terminated

A Scintigraphy Study in Adults With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
CinDome Pharma, Inc.

Completed

A Phase 2 Study of CIN-102 in Adults With Idiopathic and Diabetic Gastroparesis

Gastroparesis

United States
OBI Pharma, Inc

Completed

Trial of Active Immunotherapy With Globo H-KLH (OPT-822) in Metastatic Breast Cancer Subjects

Metastatic Breast Cancer

United States, Taiwan, Korea, Republic of, China, India
Acasti Pharma Inc.

Completed

A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2) (TRILOGY 2)

Hypertriglyceridemia

United States, Mexico, Canada
Beta Pharma, Inc.

Completed

A Phase I Study to Determine the Effect of Food on the Pharmacokinetic Profile of BPI-7711

NSCLC

China
Astellas Pharma Inc

Completed

Post-Marketing Surveillance on Long-Term Drug Use of Kiklin (Bixalomer)® Capsules in Patients With Hyperphosphatemia Receiving Peritoneal Dialysis

Chronic Renal Failure

Japan
Astellas Pharma Inc

Completed

Development of Visual Function Evaluation Method

Retinitis Pigmentosa

Japan
Acasti Pharma Inc.

Completed

A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1) (TRILOGY 1)

Hypertriglyceridemia

United States
Astellas Pharma Inc

Completed

A Study to Evaluate the Effect of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome

Constipation-predominant Irritable Bowel Syndrome (IBS-C)

Japan
Astellas Pharma Inc

Completed

A Study to Investigate the Effect of ASP1517 After Intermittent Oral Dosing in Dialysis Chronic Kidney Disease Patients With Anemia Compared With Darbepoetin as a Reference Drug

Renal Anemia Associated With Chronic Renal Failure (CRF)

Japan
Astellas Pharma Inc

Completed

A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients

Restless Legs Syndrome (RLS)

Japan
Astellas Pharma Inc

Terminated

An Open Study of ASP8273 in Patients With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) Mutations

Non-small Cell Lung Cancer

Japan, Korea, Republic of, Taiwan
Astellas Pharma Inc

Completed

A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Metformin

Healthy Subjects

Japan
Astellas Pharma Inc

Completed

Bioequivalence Evaluation of a New and Current Tablet of ASP015K

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

Comparison of Plasma Concentration Changes Between Two Types of Tablets of FK949E Administration to Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate the Efficacy and Safety of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects

Arthritis, Rheumatoid

Japan
Astellas Pharma Inc

Completed

A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe Psoriasis

Psoriasis

United States
Seldar Pharma, Inc.

Completed

A Phase 2 Pilot Study to Assess ASP7147 in Patients With Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)

Diarrhea Predominant Irritable Bowel Syndrome

United States
Kringle Pharma, Inc.

Completed

Phase I/II Study of KP-100IT in Acute Spinal Cord Injury

Spinal Cord Injuries

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate

Arthritis, Rheumatoid

United States, Poland, Colombia, Belgium, Czechia, Bulgaria, Hungary, Mexico
Astellas Pharma Inc

Completed

A Study to Compare the Effect of ASP3550 With Goserelin in Patients With Prostate Cancer

Prostate Cancer

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Pioglitazone in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of ASP1941 in Combination With α-glucosidase Inhibitor in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of ASP1941 in Japanese Type 2 Diabetes Patients

Type 2 Diabetes Mellitus

Japan
Akros Pharma Inc.

Withdrawn

Study to Evaluate Efficacy and Safety of JTT-251 in Participants With Pulmonary Arterial Hypertension (RELIEF-PAH)

Pulmonary Arterial Hypertension
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan

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