Search clinical trials for: Accelerated phase MPN

Total 19372 results

Aktion Bronchialkarzinom e.V.

Completed

Randomized Phase III-Study in Stage IIIb and IV Non-Small-Cell Lung Cancer. Sequential Single-Agent vs. Double-Agent vs. Triple-Agent Therapy.

Non-Small-Cell Lung Carcinoma

Germany
Astex Pharmaceuticals, Inc.
Eisai Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Accelerated Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
University of Bologna

Completed

Protein-Tyrosine Kinase Inhibitor (STI571) for Treatment of Patients With Ph+ Chronic Myeloid Leukemia in Accelerated and Blastic Phase (CML003)

Chronic Myeloid Leukemia

Italy
Massachusetts General Hospital
University of Pennsylvania; Beth Israel Deaconess Medical Center; Massachusetts... and other collaborators

Completed

Accelerated Mortality on Renal Replacement (ArMORR)

End Stage Renal Disease
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A Phase IB/II Clinical Study of SHR-9839 for Injection Combined With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Shanghai Juncell Therapeutics

Not yet recruiting

A Phase Ⅰb Study on Autologous GC101 TIL Injection for the Treatment of NSCLC (MIZAR-005)

Non Small Cell Lung Cancer | Non-Small Cell Lung Cancer With Mutation
Shanghai BDgene Co., Ltd.

Recruiting

A Phase Ⅰ Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis

Stromal Keratitis Caused by Herpes Simplex Virus Type I

China
Centre Hospitalier Régional d'Orléans

Not yet recruiting

Assessment of T-cell Response and In-vitro Proof-of-concept of T-cell Engineering in Chronic ESKD Patients. (LYMPHOVIRCT)

Chronic Kidney Diseases
Bayer

Not yet recruiting

A Study to Learn About the Taste of Vericiguat Given in Liquid Form in Healthy Male Participants Aged 18 to 45 Years

Heart Failure

Germany
Shanghai BDgene Co., Ltd.

Not yet recruiting

A Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis

Herpes Simplex Virus Type I Stromal Keratitis

China
Nantes University Hospital

Not yet recruiting

Pharmaco Mechanical Thrombolysis Associated With Anticoagulation Compared With Anticoagulation in the Acute Phase of Very Symptomatic Proximal Venous Thrombosis of the Lower Limbs. (PMT-DVT)

Iliofemoral Venous Thrombosis
University of Lisbon
Fundação para a Ciência e a Tecnologia; Egas Moniz - Cooperativa de Ensino...

Not yet recruiting

A Women-Focused Cardiovascular Rehabilitation Program on Adherence, Health Related Physical Fitness, and Quality of Life

Cardiovascular Diseases
Sinovac Life Sciences Co., Ltd.

Not yet recruiting

Phase I Clinical Trial of PCV24 in Adults

Pneumococcal Infectious Disease

China
Chinese PLA General Hospital

Recruiting

A Phase ll Trial of the Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma (ZARAV)

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy of Methylprednisolone Pulses in Neuroendocrine Celles Hyperplasia of Infancy : An Early Phase Study (CORTICONEHI)

Neuroendocrine Cell Hyperplasia of Infancy

France
Rophibio, Inc.

Not yet recruiting

A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-related Macular Degeneration (nAMD)

United States
University of Colorado, Boulder
National Heart, Lung, and Blood Institute (NHLBI); Northwestern University

Recruiting

Pathophysiology of Circadian Rhythm Delayed Sleep Wake Phase Disorder

Delayed Sleep Phase Syndrome | Delayed Sleep Phase

United States
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

A Prospective, Randomised Controlled, Phase II Clinical Study of Tirilizumab in Combination With Albumin-bound Paclitaxel With Cisplatin for Neoadjuvant and Adjuvant Treatment of Locally Advanced Resectable Oral Squamous Cell Carcinoma (OPTimal)

Locally Advanced Head and Neck Squamous Cell Carcinoma

China
University of Hawaii
National Heart, Lung, and Blood Institute (NHLBI); National Association of... and other collaborators

Not yet recruiting

Peau o le Vasa: Analysis of the Efficacy and Feasibility of the PILI Lifestyle Program (PLP) + Social Determinants of Health (SDOH) Intervention and Adaptation of SDOH Measures Pilot Study

Hypertension | Type 2 Diabetes Mellitus | Dyslipidemia | Pre-diabetes | Cardiometabolic Syndrome | Weight Loss Trial

United States
Fujian Cancer Hospital

Not yet recruiting

Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
AstraZeneca
Daiichi Sankyo Company, Limited 3-5-1 Nihonbashihoncho, Chuo-ku, Tokyo

Not yet recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer (DESTINY-BTC01)

Biliary Tract Cancer

Belgium, Canada, Brazil, Japan, Korea, Republic of, Taiwan, Germany, Austria, Netherlands
Amgen

Not yet recruiting

A Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (ESRD)

End-Stage Renal Disease (ESRD)
Chinese University of Hong Kong

Recruiting

Boiled Tree Nut for Oral Immunotherapy in Food-allergic Children

Food Allergy | Food Allergy in Children

Hong Kong
PharmaEssentia

Not yet recruiting

P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk

Primary Myelofibrosis | Myeloproliferative Neoplasm
Xin-Hua Xu

Recruiting

A Prospective, Open-label, Single-center, Single-arm Phase II Clinical Study of Cadonilimab (AK104) Combined With Monotherapy Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer With Negative Driver Genes and Failed Immunotherapy

Non-small Cell Lung Cancer

China
Shikai Wu

Recruiting

Development and Application Study of ePRO Software for Managing Cancer Patients Throughout the Treatment Period

Solid Tumor, Adult

China
Luye Pharma Group Ltd.

Recruiting

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Pain, Postoperative

China
Duke University

Not yet recruiting

A Phase 1 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of JCXH-211 (SElf-Replicating RNA IL-12) Intratumoral Injection in Patients With Recurrent or Progressive High-Grade Glioma (SERIL)

Recurrent or Progressive High-grade Glioma
Shanghai Bovax Biotechnology Co., Ltd.

Not yet recruiting

A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males

Anal Cancer | HPV-Related Carcinoma | Penile Cancer | Genital Wart | AIN3 | AIN2 | PIN-1 | AIN1 | PIN2 | PIN3

China
Tanta University

Not yet recruiting

Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis

Hemodialysis | ESRD | Renal Replacement Therapy | End-stage Renal Disease | Uremic Pruritus | Chronic Kidney Disease-associated Pruritus

Egypt
Shanghai BDgene Co., Ltd.

Recruiting

A Phase 1 Study of Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major

β-thalassemia

China
Genexine, Inc.
PT Kalbe Genexine Biologics

Recruiting

A Phase 3 Study of Efepoetin Alfa for Treatment of Anemia in Patients With Chronic Kidney Disease on Dialysis

Anemia of Chronic Kidney Disease

Korea, Republic of, Georgia
M.D. Anderson Cancer Center

Not yet recruiting

A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias

Refractory Acute Leukemia | Undifferentiated Leukemia | Relapsed Acute Leukemia | Bi-Phenotypic Leukemia

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Randomized Phase II Trial: Chest Wall RT Omission After Prosthetic Reconstruction

Breast Neoplasms

China
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA (DURVASCC)

Extrapulmonary Small Cell Carcinoma

Italy
AstraZeneca

Recruiting

STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic Asthma (STEP)

Severe Eosinophilic Asthma

China
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (FUMANBA-03)

Multiple Myeloma

China
HysensBio Co., Ltd

Not yet recruiting

Phase 2 Study of KH001 in Long-term Relief From Dentin Hypersensitivity

Dentin Hypersensitivity

United States
Emory University
The Marcus Foundation

Not yet recruiting

A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)

Dilated Cardiomyopathy

United States
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.

Not yet recruiting

A Study of IMM01 Plus Tiselizumab Versus Physician's Choice Chemotherapy in PD(L)1-refractory Classical Hodgkin Lymphoma

Classic Hodgkin Lymphoma
GeneQuantum Healthcare (Suzhou) Co., Ltd.

Recruiting

A Study of GQ1010 in Subjects With Advanced Solid Tumors

Advanced Malignant Solid Tumors

China
Eli Lilly and Company
Loxo Oncology, Inc.

Not yet recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (NEXUS-01)

Cervical Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Renal Pelvis Cancer | Urinary Bladder Neoplasm | Recurrent...

United States
Wuhan Union Hospital, China
Wuhan Hamilton Biotechnology Co., Ltd; Guangzhou Hamilton Biotechnology Co....

Not yet recruiting

Phase I Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis
SpinChip Diagnostics ASA
CTC Clinical Trial Consultants AB; Scandinavian Contract Research Organization

Recruiting

SpinChip Hs-cTnI Determination of the 99th Percentile URL (HEAT-3)

Acute Myocardial Infarction

Sweden
Shanghai Pulmonary Hospital, Shanghai, China
Shanghai Zhongshan Hospital; The First Affiliated Hospital of Xiamen University

Not yet recruiting

Phase II Trial of Almonertinib Plus Lastet for EGFR+ Non-small Cell Lung Cancer

Lung Cancer Non-small Cell Stage IV

China
Chengdu Baiyu Pharmaceutical Co., Ltd.

Recruiting

A Phase l Study of By101298, an Oral DNA-PK Inhibitor, in Patients With Advanced Solid Tumors

Solid Tumor, Adult

China
Chen Xiaoping

Recruiting

Precision Treatment of Unresectable HCC Guided by Multi-omics Deep Learning Models

HCC | Precision Therapy

China
Rion Inc.
Caidya Clinical Research Organization

Not yet recruiting

Phase 1b Clinical Trial to Evaluate PEP and EUFLEXXA for Knee Osteoarthritis (KOA)

Knee Osteoarthritis

United States
Kaplan Medical Center

Recruiting

Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint

Osteoarthritis Thumb

Israel
Institute of Medical Biology, Chinese Academy of...

Not yet recruiting

Phase IV Study of Concomitant Administration of the sIPV and HepA

Hepatitis A | Polio

China

Search clinical trials for: Accelerated phase MPN

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