Search clinical trials for: Drug interaction

Total 260887 results

Alexion Pharmaceuticals

Completed

Drug Interaction Study of ALXN2050 With Fluconazole and Rifampin in Healthy Adult Participants

Healthy

United States
Jiangsu Aosaikang Pharmaceutical Co., Ltd.

Completed

Drug-drug Interaction Study Beteewn ASK120067 and Rifampicin or Itraconazole

Locally Advanced or Metastatic NSCLC

China
Eli Lilly and Company

Completed

A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy Participants

Healthy

Singapore
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Interaction Between ACT-246475 and Clopidogrel, Prasugrel, and Ticagrelor in Healthy Subjects

Healthy

United States
Hanmi Pharmaceutical Company Limited

Completed

Pharmacokinetic Drug Interactions Between HGP1607 and HGP1501

Healthy Male Volunteers

Korea, Republic of
GlaxoSmithKline

Completed

Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participants

Pruritus

United States
University of Arizona
University of Virginia

Completed

Oxytocin Pathways and the Health Effects of Human-Animal Interaction

HAI

United States
Acibadem University

Completed

Interaction Between Tramadol and Ondansetron

Cholecystectomy, Laparoscopic

Turkey
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Interaction Study Between Apatinib Mesylate and Transporter Pgp Substrate Digoxin in Advanced Solid Tumor Subjects

Advanced Solid Tumor

China
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Malaria

United Kingdom
Assistance Publique - Hôpitaux de Paris

Completed

Role of the Pharmacist in Detection of Drug Interactions Before Antitumor Treatment Initiation (CHOPIN)

Neoplasm

France
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate

Healthy Participants

China
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole

Malaria

United Kingdom
Sunshine Lake Pharma Co., Ltd.

Active, not recruiting

A Study to Evaluate Drug-Drug Interaction of Larotinib With Itraconazole and Rifampin in Healthy Adult Participants (Z650)

Healthy Volunteers

China
University of Louisville
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Prospective Observational Study of Erythropoietin-Iron Interaction in Anemia of Renal Disease

Anemia of End Stage Renal Disease

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Interaction Study Between Apatinib Mesylate and Repaglinide or Bupropion in Advanced Solid Tumor Subjects

Advanced Solid Tumor

China
Dr Valerie ZELLER
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Genetic Determinants of Clindamycin/Rifampin Interaction (CLINDA-RIFAM)

VA Drug Interaction

France
Thai Red Cross AIDS Research Centre

Active, not recruiting

Assessment of Drug-drug Interactions Between Feminizing Hormone Therapy and Emtricitabine/Tenofovir Alafenamide Concomitantly for Pre-exposure Prophylaxis Among Transgender Women

Drug Interaction

Thailand
Nanjing Yoko Biomedical Co., Ltd.

Completed

Study on Tolerance, Pharmacokinetics and Drug Interaction of YK-1169 in Healthy Volunteers

Pharmacokinetics

China
Amgen

Completed

Study to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants

Healthy Participants

United States
Amgen

Completed

A Study to Evaluate the Drug-drug Interaction Effect of Rifampin on the Pharmacokinetics of AMG 510 in Healthy Participants

Healthy Participants

United States
Seoul National University Hospital

Completed

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects

Drug Interaction

Korea, Republic of
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

Drug-Drug Interaction Study of IV QPX2014 Combined With QPX7728 in Healthy Adult Subjects

Bacterial Infections

United States
Taisho Pharmaceutical Co., Ltd.

Completed

Drug-drug Interaction Study With TS-142 in Healthy Adult Subjects (Concomitant Administration of Itraconazole)

Healthy Subjects

Japan
Amgen

Completed

A Study to Evaluate the Drug-drug Interaction Effect of Itraconazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants

Healthy Participants

United States
Jazz Pharmaceuticals

Completed

An Open-label Extension Study to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol

Epilepsy

Spain, United Kingdom
Jazz Pharmaceuticals

Completed

A Randomized Controlled Trial to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol

Epilepsy

Spain, United Kingdom
Wake Forest University Health Sciences
National Institute on Aging (NIA)

Completed

The Interaction Between Diabetes and Estradiol on Human Brain Metabolism in Postmenopausal Women (E2T2D)

Dementia | Diabetes Type 2

United States
Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Drug-drug Interaction Study of FYU-981 and Oxaprozin

Healthy

Japan
Radboud University Medical Center

Completed

Determining the Clinical Relevance of the inTeraction Between AprepitaNt aNd EtoposiDe (TANNED)

Testicular Cancer

Netherlands
Abbisko Therapeutics Co, Ltd

Completed

ABSK091 Food Effect Study in Healthy Subjects

Health, Subjective | Food-drug Interaction

Taiwan
Tabula Rasa HealthCare
Cambia Health Solutions

Enrolling by invitation

Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Adults With Polypharmacy Using Data From Large Medicare and Commercially Insured Populations

COVID | Drug Effect | Adverse Drug Event | Drug Interaction

United States
Association pour le Développement et l'Organisation...

Completed

Sensory and Emotional Modulation of Dyspnea Under Artificial Ventilation in the Intensive Care Unit (Sensopnée2)

Dyspnea

France
Madrigal Pharmaceuticals, Inc.
Celerion

Completed

Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin

Healthy

United States
Tabula Rasa HealthCare

Enrolling by invitation

Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Frail Elderly Adults With Polypharmacy

COVID | Drug Effect | Adverse Drug Event | Drug Interaction

United States
Tabula Rasa HealthCare

Withdrawn

Assessment of Mortality Rates in COVID-19 Infected Populations Treated With Repurposed Medications

COVID | Drug Effect | Risk Reduction | Drug Interaction

United States
Chong Kun Dang Pharmaceutical

Completed

CKD-506 Drug-Drug Interaction Study in Healthy Male Subjects

Drug Drug Interaction

Netherlands
AstraZeneca
Parexel

Completed

A Study to Assess the Pharmacokinetics of AZD4831 When Administered Alone and in Combination With Itraconazole

Healthy Volunteers

United Kingdom
The Lymphoma Academic Research Organisation
Millennium Pharmaceuticals, Inc.

Completed

Brentuximab Vedotin Associated With Chemotherapy in Untreated Patients With Hodgkin Lymphoma. (BREACH)

Hodgkin Lymphoma

Netherlands, France, Belgium, Croatia, Denmark
Taipei Veterans General Hospital, Taiwan

Completed

Chinese Medicine Zhengyi Prescription Tea Bag

Herbal Interaction

Taiwan
Jupiter Orphan Therapeutics Inc.
National Institute on Aging (NIA)

Completed

JOTROL PK, Safety, and Food Effect Assessment

Pharmacokinetics | Food-drug Interaction | Safety

United States
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Pulmonary Tuberculoses | Other Specified Pulmonary Tuberculosis

South Africa
National Institute of Diabetes and Digestive and...

Completed

Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly

Avitaminosis | Delirium, Dementia, Amnestic, Cognitive Disorders

United States
Italfarmaco

Completed

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Drug-Drug Interaction

Portugal
SignalChem Lifesciences Corporation
Syneos Health

Completed

Crossover Study to Evaluate the Effect of Food on the Pharmacokinetics of SLC-391 in Healthy Adult Subjects

Food-drug Interaction

Canada
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Drug-drug Interaction Study of SPH3127

Drug Drug Interaction

China
The University of Hong Kong

Completed

Peer-delivered Follow-up Text Communication After a Brief Motivational Interviewing (MI) for Adolescent Drug Abusers

Drug Abuse | Adolescent Behavior

Hong Kong
Oregon Social Learning Center
National Institute on Drug Abuse (NIDA)

Completed

Oregon Supplement: Supporting Sustainable Positive Interactions in the Child Welfare System: The R3 Supervisor Strategy

Evidence-Based Practice

United States
Brigham and Women's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2

Circadian Rhythm | Melatonin | Glucose | Genes | Light

United States

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