Search clinical trials for: autologous T cells

Total 498430 results

Baylor College of Medicine
Cancer Prevention Research Institute of Texas; The Methodist Hospital Research... and other collaborators

Active, not recruiting

Her2 Chimeric Antigen Receptor Expressing T Cells in Advanced Sarcoma

Sarcoma

United States
University of Florida
Immunomic Therapeutics, Inc.

Terminated

RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.

Glioblastoma

United States
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Safety and Efficacy of Gene Therapy of the Sickle Cell Disease by Transplantation of an Autologous CD34+ Enriched Cell Fraction That Contains CD34+ Cells Transduced ex Vivo With the GLOBE1 Lentiviral Vector Expressing the βAS3 Globin Gene in Patients With Sickle Cell Disease (DREPAGLOBE) (DREPAGLOBE)

Sickle Cell Disease

France
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Bioray Laboratories
Xiangya Hospital of Central South University; The 923rd Hospital of Joint Logistics...

Completed

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

β Thalassemia Major

China
Bioray Laboratories
Changhai Hospital

Suspended

LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer

Castrate-Resistant Prostate Cancer

China
Novartis Pharmaceuticals

Active, not recruiting

Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD)

Sickle Cell Disease

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Dendritic Cell Therapy After Cryosurgery in Combination With Pembrolizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Remove by Surgery

Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Guangdong Women and Children Hospital

Completed

Effect of Autologous Cord Blood-mononuclear Cells Infusion on Immune Microenvironment in Infants Born Very Preterm in NICU

Immunomodulation Effect

China
Intellia Therapeutics

Terminated

Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, United Kingdom
University of Nebraska
Biogen

Completed

Monoclonal Antibody Therapy in Relapsed Non-Hodgkin's After Chemotherapy and Autologous Stem Cell Transplantation

Lymphoma

United States
Juno Therapeutics, a Subsidiary of Celgene

Completed

Lisocabtagene Maraleucel (JCAR017) as Second-Line Therapy (TRANSCEND-PILOT-017006)

Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin | Lymphoma, Nonhodgkin

United States
University of California, Davis

Active, not recruiting

Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy

Diabetic Retinopathy | Retinitis Pigmentosa | Non-exudative Age-related Macular Degeneration | Retina Vein Occlusion | Hereditary Macular Degeneration

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma

Anaplastic Large Cell Lymphoma, ALK-Positive | Hepatosplenic T-Cell Lymphoma | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Anaplastic Large Cell Lymphoma, ALK-Negative | Stage II Angioimmunoblastic T-cell Lymphoma | Stage II Enteropathy-Associated T-Cell Lymphoma | Stage III Angioimmunoblastic... and other conditions

United States
Jacob L. Sellon, M.D.

Completed

Autologous Culture Expanded Mesenchymal Stromal Cells for Knee Osteoarthritis

Osteoarthritis, Knee

United States
University Hospital, Bordeaux

Completed

Evaluation of the Success of Prophylactic Enteral Nutrition in Therapeutic Intensification With Autograft of Autologous Hematopoietic Cells in Hematology (GAGNE)

Lymphoma | Myeloma

France
Takara Bio Inc.

Completed

Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients With Synovial Sarcoma

Synovial Sarcoma

Japan
Juno Therapeutics, a Subsidiary of Celgene
Bristol-Myers Squibb

Completed

A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-007)

Neoplasms | Neoplasms by Histologic Type | Lymphoma | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphoproliferative Disorders | Lymphatic Diseases | Immunoproliferative Disorders | Lymphoma, Non-Hodgkin | Immune System Disorder

United States
Ruijin Hospital
Regend Therapeutics

Completed

Autologous Transplantation of Bronchial Basal Cells for Treatment of Bronchiectasis

Bronchiectasis

China
SCRI Development Innovations, LLC
Bristol-Myers Squibb

Completed

Elotuzumab, Lenalidomide and Dexamethasone in Treatment of Transplant-Eligible Newly Diagnosed Multiple Myeloma Patients

Multiple Myeloma

United States
Massachusetts Eye and Ear Infirmary
Dana-Farber Cancer Institute

Completed

Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft (CALEC)

Limbal Stem Cell Deficiency

United States
Juan C. Ramos, MD

Withdrawn

Safety Trial of STING-dependent Activators and Stimulated Dendritic Cells for Aggressive Relapsed/Refractory Leukemias

Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Refractory Leukemia | Adult T-Cell Leukemia/Lymphoma | Relapsed Leukemia

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Phase I Study of Bendamustine and Melphalan Conditioning and Autologous Stem Cell Transplantation for Treatment of Multiple Myeloma and Relapsed/Refractory B-cell Lymphoma in Elderly Patients

Lymphoma

United States
University of Chile

Completed

Immunization With Autologous Dendritic Cells and Tumor Lysates in Melanoma Patients

Stage III Malignant Melanoma of Skin AJCC V6 | Stage IV Malignant Melanoma of Skin

Chile
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Arthritis Research UK

Completed

Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis (AutoDECRA) (AutoDECRA)

Rheumatoid Arthritis

United Kingdom
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

Autologous/Allogeneic TGFbeta-resistant LMP-specific CTL, Lymphoma (TGF-beta) (TGF-beta)

Lymphoma | Lymphoma, Non-Hodgkin | Relapse | Hodgkin's Disease

United States
Washington University School of Medicine
Amgen

Completed

Blinatumomab Consolidation Post Autologous Stem Cell Transplantation in Patients With Diffuse Large B-Cell Lymphoma (DLBCL)

Diffuse Large B Cell Lymphoma

United States
Hemostemix

Completed

ACP-01 in Patients With Critical Limb Ischemia

Critical Limb Ischemia

United States, Canada
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Specialized Immune Cells (nCTLs) and a Vaccine (Alpha-type-1 Polarized Dendritic Cells) in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stage III Fallopian Tube Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage III Primary Peritoneal Cancer AJCC v8 | Stage IIIA Fallopian Tube Cancer AJCC v8 | Stage IIIA Ovarian Cancer AJCC v8 | Stage IIIA Primary Peritoneal Cancer AJCC v8 | Stage IIIA1 Fallopian Tube Cancer AJCC v8 | Stage... and other conditions

United States
Sangamo Therapeutics

Active, not recruiting

A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease

Sickle Cell Disease

United States
Campus Bio-Medico University
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; Center for Outcomes...

Active, not recruiting

Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD (ACTIVE)

Chronic Low-back Pain | Intervertebral Disc Degeneration

Italy
Craig van Horne, MD, PhD

Active, not recruiting

Cont. of a Study to Evaluate Implanting Peripheral Nerve Grafts Into Subjects With Parkinson's Disease (PD) During DBS (CAPNG)

Parkinson's Disease

United States
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Intracoronary Infusion of Mononuclear Cells Autologous Bone Marrow in Patients With Chronic Coronary Occlusion and Ventricular Dysfunction, Previously Revascularized.

Coronary Atherosclerosis and Other Heart Disease

Spain
Instituto Venezolano de Investigaciones Cientificas
Hospital Central Dr. Plácido D. Rodriguez Rivero; Instituto Autónomo Hospital...

Enrolling by invitation

Treatment of Nonunion Fractures With Mesenchymal Stromal Cells (MSCs) (MSC)

Pseudarthrosis | Non Union Fracture | Pseudoarthrosis of Bone | Nonunion Bone Fracture

Venezuela
Matthias Löhr

Completed

Autologous Cell Sheets Transplantation After ESD in the Esophagus (CellSheet2)

Barrett Esophagus

Sweden
Johns Hopkins University
United States Department of Defense; The Geneva Foundation

Suspended

Stem Cells vs. Steroids for Discogenic Back Pain

Degenerative Disc Disease | Chronic Low Back Pain

United States
W. Dalton Dietrich
The Miami Project to Cure Paralysis

Active, not recruiting

Autologous Human Schwann Cells in Peripheral Nerve Repair

Peripheral Nerve Injuries

United States
Shanghai East Hospital
Regend Therapeutics

Completed

Autologous Lung Stem Cell Transplantation in Patients With Interstitial Lung Diseases

Interstitial Lung Diseases

China
University of Erlangen-Nürnberg Medical School

Completed

Autologous Ex Vivo Expanded Regulatory T Cells in Ulcerative Colitis

Autoimmune Diseases | Ulcerative Colitis

Germany
M.D. Anderson Cancer Center

Completed

Modified T Cells, Chemotherapy, and Aldesleukin With or Without LV305 and CMB305 in Treating Participants With Advanced or Recurrent Sarcoma

Recurrent Synovial Sarcoma | HLA-A*0201 Positive Cells Present | NY-ESO-1 Positive Tumor Cells Present | Recurrent Myxoid Liposarcoma

United States
Shanghai East Hospital
Bio4T2 LLC

Active, not recruiting

A Clinical Study to Evaluate B4T2-001 CAR T Cells in the Treatment of Advanced Solid Tumors

Advanced Solid Tumor

China
University of Nebraska
National Cancer Institute (NCI)

Completed

Lenalidomide Therapy After Chemotherapy & Stem Cell Transplant in Treating Chemotherapy Resistan Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma | Anaplastic Large Cell Lymphoma, ALK-Negative | Recurrent Anaplastic Large Cell Lymphoma

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Rituximab, Carmustine; Cytarabine, Etoposide, & Melphalan; Stem Cell Transplantation for Non-Hodgkin's Lymphoma

Lymphoma

United States
Lisata Therapeutics, Inc.

Terminated

Vaccine Therapy in Treating Patients With Kidney Cancer

Kidney Cancer

United States
Michael Murphy
Zimmer Biomet

Completed

Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA) (MarrowCHAMP)

Peripheral Artery Disease | Critical Limb Ischemia | Vascular Disease

United States
University of Delaware

Withdrawn

Knee Injections for the Clinical Management of Knee OsteoArthritis (KICK-OA)

Knee Osteoarthritis

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women)

Breast Cancer

United States
University of Nebraska
Millennium Pharmaceuticals, Inc.

Completed

VELCADE®-BEAM and Autologous Hematopoietic Stem Cell Transplantation for Non-Hodgkin's Lymphoma, or Mantle Cell Lymphoma

Mantle Cell Lymphoma | Non-hodgkin's Lymphoma

United States
Maxivax SA

Active, not recruiting

MVX-ONCO-1 in Patients With Solid Tumor

Cancer | Solid Tumor

Switzerland
Hope Biosciences Stem Cell Research Foundation

Available

Intermediate Size Expanded Access Protocol Using Autologous HB-adMSCs for the Treatment of Parkinson's Disease

Parkinson Disease

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