Search clinical trials for: cholinesterase inhibitor

Total 68193 results

Thrombologic ApS
Rigshospitalet, Denmark; Anders Perner

Terminated

Integrilin and Ilomedin in Combination in Comparison to Standard Treatment in Severe Pneumonia Patients With Severe Sepsis

Pneumonia

Finland, Denmark
Sunnybrook Health Sciences Centre

Completed

A Genetic and Perfusion Study of Response to Cognitive Enhancers in Lewy Body Disease

Lewy Body Disease

Canada
Per Borghammer
Lundbeck Foundation

Completed

Study to Investigate the Ability of [11C]Donepezil PET to Image the Parasympathetic Nervous System

Parkinson's Disease

Denmark
Stanford University
National Institute of Mental Health (NIMH); Autism Speaks

Completed

Randomized Controlled Study of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
Sanofi

Completed

Effect of Different Doses of SAR110894 on Cognition in Patients With Mild to Moderate Alzheimer's Disease on Donepezil

Dementia Alzheimer's Type

Australia, Italy, France, Portugal, United States, Canada, Germany, Poland, Spain
Coastal Anesthesiology Consultants

Completed

Does Residual Muscular Weakness Lead to an Increase in Respiratory Complications in Bariatric Patients?

Morbid Obesity | Respiratory Complication

United States
Cairo University
National Liver Institute, Egypt

Completed

Sugammadex Versus Neostigmine in Patients With Liver Cirrhosis Undergoing Liver Resection

Cirrhosis and Chronic Liver Disease

Egypt
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University

Completed

Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors

Cognitive Dysfunction | Brain Cancer | Brain Tumor | Cns Cancer

United States
Samsung Medical Center
Eisai Korea Inc.

Completed

Clinical Trial of Donepezil Between the Naive Group and the Switching Group

Dementia | Alzheimer's Disease

Korea, Republic of
Samsung Medical Center
Eisai Korea Inc.

Completed

Clinical Trial of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia

Dementia | Alzheimer's Disease

Korea, Republic of
Samsung Medical Center
Janssen Korea, Ltd., Korea

Completed

Characteristics of Treatment Responders to Galantamine

Dementia

Korea, Republic of
Konkuk University Medical Center

Unknown

The Clinical Changes Before and After Sugammadex in the Patients Undergoing Hip Surgery on the Aspect of Delirium

Delirium

Korea, Republic of
Onze Lieve Vrouw Hospital

Completed

Electromyographic Activity of the Respiratory Muscles During Neostigmine or Sugammadex Enhanced Recovery After Neuromuscular Blockade (REDNESII)

Respiratory Muscles | Electromyography

Belgium
Merck Sharp & Dohme LLC

Completed

Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)

Dementia
Eisai Inc.

Completed

Safety, Tolerability, and Efficacy of Donepezil (Aricept) in Parkinson' s Disease (PD) Patients With Dementia

Parkinson's Disease | Dementia

United Kingdom
Eisai Inc.

Completed

A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Rifampin, Digoxin, or Donepezil

Healthy Subjects

United States
Eisai Limited

Completed

The Efficacy, Safety, And Tolerability Of Donepezil HCl (E2020) In Patients With CADASIL Who Have Cognitive Impairment

Cognitive Impairment

United States, Spain, Australia
Merck Sharp & Dohme LLC

Completed

Comparison of 2.0 mg/kg Sugammadex and Neostigmine at Reappearance of T2 in Chinese and European Subjects (Study 19.4.324)(P05768AM1)(COMPLETED)

Anesthesia, General | Neuromuscular Blockade
Ever Neuro Pharma GmbH

Withdrawn

Cerebrolysin Compared to Donepezil in Patients With Mild to Moderate Dementia of Alzheimer's Type (DAT) (DAT)

Alzheimer Disease

Austria
Osaka University

Completed

Donepezil Therapy and Changes of Symptoms and Glucose Metabolism in Patients With Dementia With Lewy Bodies (DLB)

Dementia With Lewy Bodies (DLB)

Japan
Centre Hospitalier Universitaire de Nice

Completed

MELA Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy Volunteers (MELA)

Healthy

France
Korea University Anam Hospital

Unknown

Effectiveness of Sugammadex in LMS Surgery

Muscle Relaxation
Danbury Eye Physicians & Surgeons, PC

Unknown

Echothiophate Iodide for the Prevention of Progression of Myopia

Myopia

United States
Merck Sharp & Dohme LLC

Completed

A Study to Test the Performance of the CogState Computerized Neuropsychological Battery in Patients With Alzheimer's Disease (0000-086)(COMPLETED)

Alzheimer's Disease
Hospital Sultanah Aminah Johor Bahru

Completed

Optimal Relaxation Technique for Laparotomies With Rocuronium Infusion Followed by Sugammadex Reversal (ProjectO5Rs)

Underdosing of Skeletal Muscle Relaxants for Laparotomy | Reversal of Skeletal Muscle Relaxant

Malaysia
Inje University

Unknown

The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With Dementia (CUPID)

Parkinson's Disease

Korea, Republic of
Palacky University
University Hospital Olomouc; Masaryk Hospital Usti nad Labem

Unknown

Deep Neuromuscular Blockade During Robotic Radical Prostatectomy

Neuromuscular Blockade

Czech Republic
Merck Sharp & Dohme LLC

Completed

BOLD Functional Magnetic Resonance Imaging (fMRI) and Cerebral Blood Flow Measurements as Biomarkers for Cognition Enhancing Drugs (3134-006)

Dementia
Merck Sharp & Dohme LLC

Withdrawn

Rocuronium + Sugammadex vs. Succinylcholine + Cisatracurium + Neostigmine/Atropine in Obese Participants (MK-8616-104) (BENN)

Neuromuscular Blockade
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Galantamine Effects on Nicotine Responses in Smokers

Smoking | Tobacco Withdrawal

United States
Yonsei University

Completed

The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy

Robot-Assisted Laparoscopic Radical Prostatectomy

Korea, Republic of
Targacept Inc.

Completed

Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)

Alzheimer's Disease

United States, Ukraine, Czech Republic, Romania, Slovakia
Per Borghammer
Lundbeck Foundation; Jascha Fonden; Fonden af 2. Juli 1984 til bekæmpelse af...

Completed

[11C]Donepezil PET For Imaging The Autonomous Nervous System In Parkinsons Disease

Parkinson's Disease

Denmark
Zeria Pharmaceutical

Completed

To Evaluate the Efficacy and Safety in Subjects With Functional Dyspepsia

Functional Dyspepsia

Belgium
Seoul National University Hospital
Novartis Korea Ltd.

Unknown

Brain Changes by Rivastigmine According to Butyrylcholinesterase Alleles

Alzheimer's Disease

Korea, Republic of
University of Rochester

Completed

Phamacological Reversal of Airway Instability During Sedation (PHYSO)

Upper Airway Obstruction

United States
Yonsei University

Completed

A Double-blind, Randomized, Parallel Design Study to Compare the Effectiveness of Sugammadex Versus Neostigmine in Improving Surgical Condition in Subjects Undergoing Laryngeal Microsurgery

General Anesthesia

Korea, Republic of
Annovis Bio Inc.

Terminated

Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive Impairment

Alzheimer's Disease | Amnestic Mild Cognitive Impairment

United States
Onze Lieve Vrouw Hospital
Universiteit Antwerpen; MSD Belgium BVBA

Completed

Functional Respiratory Imaging After Neostigmine or Sugammadex (FRINeoS)

Respiratory-Gated Imaging Techniques

Belgium
T.C. ORDU ÜNİVERSİTESİ

Completed

Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular Blockade

Intraocular Pressure Changes During Tracheal Extubation

Turkey
Chung-Ang University Hosptial, Chung-Ang University...

Completed

Rivastigmine Patch Effect on the Post-operative Delirium in Patients at Risk of Dementia.

Delirium
University Hospital, Lille
Innovative Medicines Initiative

Completed

Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development (PharmacogWP3)

Alzheimer Disease | Battery

France
Duke University
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.; Taishoff Family...

Completed

Rivastigmine Study in Adolescents With Down Syndrome (DS-Riv)

Down Syndrome

United States
Icure Pharmaceutical Inc.

Completed

A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects.

Alzheimer Disease

Korea, Republic of
Pfizer

Terminated

Vaspect Study - An Open-Label Trial Of Donepezil in Vascular and Mixed Dementia

Dementia, Vascular | Dementia, Mixed

Canada
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774)

Anesthesia
Pfizer

Completed

A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes

Alzheimer Disease

Sweden
NYU Langone Health
Novartis

Completed

Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial

Delirium | Postoperative Cognitive Dysfunction

United States
Qualissima
European Union

Completed

Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers

Healthy

France
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Rivastigmine and Huperzine A as Treatments for Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States

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