Search clinical trials for: mammalian target of rapamycin (mTOR)

Total 431830 results

Institute of Mental Health, Singapore
National University of Singapore

Not yet recruiting

A Novel Individualized Connectome-guided Approach for Precision Intermittent Theta Burst Stimulation for Depression

Depression
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies

Myeloid Malignancies | Lymphodepleting Chemotherapy

United States
Biohaven Therapeutics Ltd.

Recruiting

A Phase 1/2 Study of PBI-410 in Advanced Solid Tumors

Solid Tumor

United States
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
Brigham and Women's Hospital
National Institutes of Health (NIH)

Not yet recruiting

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness (Searchlight)

Mood Disorders | Schizophrenia | Obsessive-Compulsive Disorder | Generalized Anxiety Disorder | Major Depressive Disorder | Depression, Anxiety | Psychiatric Disorder | Mental Disorder
University of Alabama at Birmingham

Not yet recruiting

Target Oxygen Ranges in Infants With Pulmonary Hypertension (TORPH)

Pulmonary Hypertension | Bronchopulmonary Dysplasia
University of Illinois at Chicago

Recruiting

Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.

Kidney Diseases | Frailty | Pain, Chronic | Dialysis; Complications

United States
Saint Petersburg State University, Russia

Recruiting

Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer

Anaplastic Thyroid Cancer

Russian Federation
Stanford University
National Institute of Mental Health (NIMH)

Not yet recruiting

A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety (R33 Phase)

Depression | Insomnia

United States
Ting Chang, MD

Not yet recruiting

Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis

Myasthenia Gravis

China
Zhejiang University
Hangzhou Qihanjiyin Biotech Co.,Ltd.

Recruiting

Natural Killer(NK) Cell Therapy Targeting CLL1 or CD33 in Acute Myeloid Leukemia

AML, Adult

China
The Cooper Health System
Won Sook Chung Foundation

Not yet recruiting

Emulated Study of Vitamin D Correction vs Non-Correction

Vitamin D Deficiency
University of Alabama at Birmingham

Not yet recruiting

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

Non Small Cell Lung Cancer

United States
University of Kansas Medical Center

Recruiting

Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.

Cystic Fibrosis

United States
Beijing 302 Hospital
Beijing GD Initiative Cell Therapy Technology Co., Ltd.; Chinese Academy of...

Not yet recruiting

Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial for First-line Treatment of Hepatocellular Carcinoma

Hepatocellular Carcinoma
Beijing 302 Hospital
Beijing GD Initiative Cell Therapy Technology Co., Ltd.; Chinese Academy of...

Not yet recruiting

Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial of Hepatocellular Carcinoma Resistant to PD-1 Monoclonal Antibody

Hepatocellular Carcinoma
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Recruiting

Early Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Systemic Lupus Erythematosus | Systemic Sclerosis | Idiopathic Inflammatory Myopathies | Primary Sjögren Syndrome | IgG4 Related Disease

China
West China Hospital

Not yet recruiting

AI App for Management of Atopic Dermatitis

Artificial Intelligence | Atopic Dermatitis
Peking University First Hospital

Recruiting

Comparison of MRI AI-cTB Versus Routine cTB in Prostate Cancer Diagnosis: a Prospective Randomized Controlled Trial

Prostate Cancer

China
Central Hospital, Nancy, France

Not yet recruiting

Interventional Reference Levels (IRL) in Digestive Endoscopy (EndoscopX)

Each Endoscopic Intervention Using X-rays

France
Saint Petersburg State University, Russia

Recruiting

Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy

Anaplastic Thyroid Cancer

Russian Federation
New York State Psychiatric Institute
Columbia University

Not yet recruiting

RCT of a Brief Video Intervention Targeting Peer Inclusion to Reduce Depression-related Stigma in Adolescents

Depression | Stigma, Social | Adolescent - Emotional Problem | Help-Seeking Behavior

United States
Wuhan Union Hospital, China

Not yet recruiting

Study of SYS6020 in BCMA-positive Multiple Myeloma

Multiple Myeloma
Royal Marsden NHS Foundation Trust
Imperial College London; Institute of Cancer Research, United Kingdom; RM Partners...

Recruiting

The Man Van Project (MV)

Smoking | Alcoholism | Urologic Diseases | Hypertension | Diabetes | Prostate Cancer | Bladder Cancer | Renal Cancer | Urologic Cancer | Mental Health Issue | Testis Cancer

United Kingdom
Shandong Cancer Hospital and Institute

Recruiting

Sintilimab Combined With Fruquintinib/Regorafenib ± Radiotherapy for Third-line Treatment of Advanced Metastatic Colorectal Cancer

Colorectal Cancer | Radiotherapy | Immunotherapy | Targeted Therapy

China
The Affiliated Hospital of Qingdao University

Recruiting

Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer (PILOT)

Non-small-cell Lung Cancer (NSCLC)

China
Zhu Xiaofan

Recruiting

CD19-targeted CAR T Cell Autotransfusion for the Treatment of Recurrent/Refractory B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Children With CD19+

B Lymphoblastic Lymphoma | B Lymphocytic Leukemia

China
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Identification of Biomarkers and Molecular Targets Involved on Intervertebral Disc Degeneration and Discogenic Pain

Intervertebral Disc Degeneration | Discogenic Pain | Discogenic Disease

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness

Glioma | Glioblastoma | Glioma Glioblastoma Multiforme

Italy
UNC Lineberger Comprehensive Cancer Center
Bellicum Pharmaceuticals

Not yet recruiting

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

Breast Cancer | Triple Negative Breast Cancer | Relapse | Resistant Cancer

United States
Zhejiang University
Shanghai YaKe Biotechnology Ltd.

Recruiting

CD19-BAFF CAR-T Cells Therapy for Patients With Relapsed / Refractory B-cell ALL and B-cell NHL

Non-hodgkin Lymphoma,B Cell | Acute Lymphoblastic Leukemia,B-Cell

China
Jie Zhong

Not yet recruiting

Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy

Diabetic Retinopathy | Retinal Vein Occlusion | Vitreous Hemorrhage | Retinal Vasculitis | Vascular Retinopathy of Left Eye (Disorder) | Vascular Retinopathy of Right Eye (Disorder)
Baylor College of Medicine

Not yet recruiting

CHIMERIC ANTIGEN RECEPTOR TREATMENT TARGETING CD70 (SEVENTY) (CASEY)

Lymphoma | Leukemia, Myeloid, Acute | Leukemia, T-Cell | Leukemia, B-cell

United States
Pontificia Universidad Catolica de Chile

Recruiting

Characterization of the Temporal Profile of the Anti-nociceptive Effect of Ketamine Bolus Measured With ANI (Keta-ANI)

Analgesia | Ketamine | Pharmacokinetic

Chile
Jonsson Comprehensive Cancer Center

Not yet recruiting

A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma

Diffuse Hemispheric Glioma, H3 G34-Mutant

United States
Hospital Universitari de Bellvitge

Recruiting

ICG vs Blue Patent as a Tracer in the Performance of TAD in Patients With cN1 Breast Carcinoma After Neoadjuvant Chemotherapy

Breast Cancer | Axillary Metastases

Spain
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease (VT-NMD)

Neuromuscular Diseases

United Kingdom
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Multi-modal Characterisation of Hepatocellular Carcinoma (HCC) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort (OPERANDI-HCC)

Hepatocellular Carcinoma | Radioembolization

France
University Hospital, Geneva
University of Geneva, Switzerland

Recruiting

Mental Imagery and Targeted Memory Reactivation in Insomnia

Insomnia Disorder

Switzerland
Autolus Limited

Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Patients With Severe, Refractory Systemic Lupus Erythematosus (SLE) (CARLYSE)

Systemic Lupus Erythematosus

United Kingdom
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Target of Suv420h1/2 in Hepatocytes

NAFLD

Italy
Centre Hospitalier Universitaire de Nice

Recruiting

Vitiligo Treatment by Targeting TYK2 Mediated Responses (ViTYK)

Vitiligo, Generalized

France
Prince of Songkla University

Recruiting

Differences in Rate of Decline in CT-defined Skeletal Muscle Mass and Physical Performance in Patients With Advanced Non-small Cell Lung Cancer Receiving Chemotherapy and Targeted Therapy/Immunotherapy, Before and After Treatment.

Sarcopenia | Advanced Lung Cancer

Thailand
IRCCS San Raffaele

Not yet recruiting

Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models

Pituitary Adenoma | Acromegaly | Hypopituitarism | Adiposity | Cushing Syndrome | Endocrine Disorders
University Health Network, Toronto

Not yet recruiting

Pilot Trial of Virtual and In-person STEP2 (STEP2)

Oncology
Complejo Hospitalario Universitario de Santiago
Instituto de Salud Carlos III; University of Santiago de Compostela; Instituto... and other collaborators

Recruiting

Glycoxidation, Arterial Biomechanics, and Target Organ Damage (GlycOxiTod)

Oxidative Stress | Cardiovascular Risk | Target Organ Damage

Spain
The Canadian College of Naturopathic Medicine

Not yet recruiting

Maitake for Integrative Cancer Care (Maitake)

Cancer

Canada
Fudan University

Not yet recruiting

Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022)

Lung Cancer | Minimal Residual Disease | EGFR Gene Mutation
University of Illinois at Chicago

Not yet recruiting

Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer (MindCRC)

Colon Cancer | Mindfulness | Females

United States
Chinese PLA General Hospital

Recruiting

TCR Reserved and Power3 Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma

Non-hodgkin Lymphoma

China

Search clinical trials for: mammalian target of rapamycin (mTOR)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in United Arab Emirates

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations