Search clinical trials for: methotrexate toxicity

Total 3406 results

Assiut University

Not yet recruiting

Use of Antiarrhythmic Drugs in Pediatrics

Antiarrhythmic Toxicity
Hospices Civils de Lyon

Recruiting

NIRAPK : Study of the Relationship(s) Between Clinical, Biological and Pharmacokinetic Metrics and Toxicities When Niraparib is Used as Maintenance Treatment for Ovarian Cancer Patients. (NIRAPK)

Adult Patients With Platinum-sensitive, Relapsed, High Grade Serous Epithelial Ovarian Cancer

France
Charite University, Berlin, Germany

Recruiting

A Phase I/II Study to Investigate the Use of VORAXAZE™ as Intended Intervention in Patients With CNSL (VALIDATE)

CNS Lymphoma

Germany
Zhejiang University

Recruiting

Ruxolitinib With Calcineurin and Methotrexate vs. Calcineurin Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation

Graft Versus Host Disease

China
University of Milano Bicocca

Recruiting

POst-Prostatectomy Ablative Radiation Therapy (POPART)

Radiation Toxicity

Italy
University of Milano Bicocca

Recruiting

ABlative Radiotherapy (for) Unfavorable Prostate Tumors (ABRUPT)

Prostate Cancer

Italy
Tehran University of Medical Sciences

Recruiting

Clinical Response and Toxicity of Hypo-fractionated Chemoradiotherapy in Cervix Cancer

Cervix Uteri Cancer

Iran, Islamic Republic of
Ass. Prof. Jan Nyman

Recruiting

Study on Proton Radiotherapy of Thymic Malignancies (PROTHYM)

Thymus Neoplasms | Cardiotoxicity | Pulmonary Toxicity

Sweden
Assiut University

Not yet recruiting

Hepatorenal Dysfunctions Among Workers Exposed To Petroleum Products

Petroleum Product Toxicity
Ain Shams University

Recruiting

Role of Intravenous Lipid Emulsion in Improving Coma of Acute Antipsychotics Poisoning

Coma

Egypt
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

A Single-cell Approach to Identify Biomarkers of Pulmonary Toxicity for Immune Checkpoint Blockade

Immunotherapy | Pneumonitis, Interstitial | Immune-related Adverse Events

Belgium
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

A Single-cell Approach to Identify Biomarkers of Efficacy and Toxicity for ICI in NSCLC

NSCLC | Lung Diseases, Interstitial | Immunotherapy

Belgium
Medical University of Graz

Recruiting

Fetal Haemoglobin and Cerebral and Peripheral Oxygenation. (HbFIN)

Preterm Birth | Oxygen Toxicity | Fetal Hemoglobin

Austria
Hospital San Carlos, Madrid

Recruiting

Efficacy, Safety and Costs of Methotrexate, Adalimumab, or Their Combination in Non-infectious Non-anterior Uveitis (Co-THEIA)

Uveitis

Spain
Centre Hospitalier Universitaire, Amiens

Recruiting

Impact of a Multidisciplinary Consultation Program on Drug Adherence in First Oral Anticancer Treatment (IMPAM)

Multidisciplinary Consultation Program | Adherence to Oral Anticancer Treatment | Drug Related Toxicity | Securing Medication Management

France
Azienda Ospedaliero-Universitaria Careggi

Recruiting

Stereotactic Radiotherapy in Association With Immunotherapy for the Treatment of NSCLC Brain Metastases (STRAITLUC)

Brain Metastases From NSCLC

Italy
Lauren Hamel

Recruiting

DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer (DISCO)

Cancer | Breast Cancer | Prostate Cancer | Financial Toxicity | Question Prompt List

United States
Radboud University Medical Center
UMC Utrecht; Catharina Ziekenhuis Eindhoven; Amsterdam UMC, location VUmc; Academisch... and other collaborators

Recruiting

Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome (AMICO)

Colorectal Cancer | Chemotherapeutic Toxicity | Lifestyle | Survivorship

Netherlands
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage... and other conditions

United States
University of Chicago

Recruiting

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

Acute Lymphoblastic Leukemia | Lymphoblastic Leukemia | ph+ Acute Lymphoblastic Leukemia

United States
Institut National de la Santé Et de la Recherche...
University of Zurich; Aarhus University Hospital; KU Leuven; University Hospital... and other collaborators

Recruiting

Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy (HARMONIC-RT)

Neoplasms

Denmark, France, Belgium, Germany
Henan Cancer Hospital

Recruiting

Rituximab, Lenalidomide Combined With Methotrexate and Temozolomide For Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma

China
Oklahoma Medical Research Foundation
Yale University; Columbia University; NYU Langone Health; Piedmont Heart Institute...

Recruiting

Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE (NAIVE)

Systemic Lupus Erythematosus (SLE)

United States
Seattle Children's Hospital
Mansoura University; Boston Children's Hospital, Boston, MA, USA; Hospital for... and other collaborators

Recruiting

CHronic Nonbacterial Osteomyelitis International Registry (CHOIR) (CHOIR)

Chronic Recurrent Multifocal Osteomyelitis | Chronic Nonbacterial Osteomyelitis

United States
Leiden University Medical Center
Jessa Hospital; The Netherlands Cancer Institute

Recruiting

Response and Toxicity Prediction by Microbiome Analysis After Concurrent Chemoradiotherapy (Prediction)

Immunotherapy | Non Small Cell Lung Cancer Stage III

Netherlands, Belgium
Sherief Abd-Elsalam

Recruiting

Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis

Beta Blocker Toxicity

Egypt
UNC Lineberger Comprehensive Cancer Center

Recruiting

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

Toxicity | Radiation Toxicity

United States
University Hospital, Caen
Heidelberg University; Groupe Hospitalier Pitie-Salpetriere; University Hospital... and other collaborators

Recruiting

Atrial Fibrillation in Active Cancer Patients (AFIB-CANCER)

Cancer | Atrial Fibrillation | Drug Toxicity | Cardiovascular Complication

France
Jun Zhang, MD, PhD
Rhode Island Hospital

Recruiting

Using Microbiome to Predict Durvalumab Toxicity in Post- Concurrent Chemoradiation Therapy (CCRT) NSCLC Patients (Microdurva)

NSCLC, Stage III | Locally Advanced Lung Carcinoma

United States
University of Aarhus
Aarhus University Hospital; Westmead and Blacktown Hospital, Sydney West Radiation...

Recruiting

Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer (ASPECT)

Lung Cancer | Pulmonary Disease | Radiation Pneumonitis | Lung Function Decreased | Radiation-Induced Disorder

Australia, Denmark
Peking University People's Hospital

Recruiting

MTX and Steroid for aGVHD Treatment

Acute GVH Disease

China
University of Calgary
The Hospital for Sick Children; CHU de Quebec-Universite Laval; McMaster University and other collaborators

Recruiting

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Radiation Toxicity | Radiation Exposure | DIPG | Brain Tumor, Pediatric, Recurrent | Brain Tumor, Pediatric | Brain Tumor, DIPG

Canada
University Hospital, Brest

Recruiting

PRediction Of DIverse Glucocorticoids toxIcity OUtcomeS (PRODIGIOUS)

Giant Cell Arteritis | Polymyalgia Rheumatica | ANCA Associated Vasculitis | Inflammatory Rheumatism | Idiopathic Inflammatory Myopathies | Systemic Autoimmune Disease

France
Aarhus University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Recruiting

TDM for Optimized Outcome in Patients With mRCC.

Kidney Cancer | Renal Cell Carcinoma Metastatic | Drug Toxicity | Drug Side Effect | Drug Mechanism

Denmark
National Science Centre, Poland
Medical University of Warsaw

Recruiting

The New LC-MS/MS Method for Determination of Unbound Tacrolimus in Plasma (FreeTAC)

Kidney Transplant Rejection | Liver Transplant; Complications | Immunosuppression | Metabolism Medication Toxicity | Genetic Predisposition | Kidney Transplant; Complications | Liver Transplant Rejection

Poland
Cairo University

Recruiting

Rebamipide (Regular & Nanoparticulated) vs. Clobetasol in Management of Methotrexate-Induced Oral Ulceration in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Egypt
University of Miami
Florida Breast Cancer Foundation; VAUGHN-JORDAN FOUNDATION, INC.

Recruiting

Application of Chinese Herbal Complementary and Alternative Medicine (CAM) to Improve Human Health and to Further Botanical and Horticultural Sciences

Skin Toxicity

United States
Institut de cancérologie Strasbourg Europe

Recruiting

Identification of Genetic Determinants for Treatment Resistance/Sensitivity and/or Toxicity in Adjuvant Setting for HER2 Positive Breast Cancer (SIGHER)

HER2-positive Breast Cancer

France
University of Kansas Medical Center

Recruiting

Pharmacogenomic Modulators of Impaired Exercise Adaptation in Statin Users

HMG-CoA Reductase Inhibitor Toxicity

United States
Medical University Innsbruck

Recruiting

Cryotherapy vs. Cryocompression for Preventing Chemotherapy-induced-peripheral-neuropathy in Women Undergoing Chemotherapy

Chemotherapeutic Toxicity | Chemotherapy-induced Peripheral Neuropathy | Chemotherapeutic Agent Toxicity

Austria
Western Sydney Local Health District
Bristol-Myers Squibb; University of Western Sydney

Recruiting

Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin Toxicity (ICEMELT)

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Gastric Cancer | Mesothelioma | Endometrial Cancer | Lung Cancer, Nonsmall Cell

Australia
National Cancer Institute (NCI)

Recruiting

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Renal Pelvis and Ureter Urothelial Carcinoma

United States
University of Sao Paulo General Hospital
Libbs Farmacêutica LTDA

Recruiting

GVHD Prophylaxis With Methotrexate in Haploidentical HCT Using Posttransplant Cyclophosphamide

Hematopoietic Neoplasm | Graft Vs Host Disease

Brazil
The Clatterbridge Cancer Centre NHS Foundation...
University of Liverpool

Not yet recruiting

Phase II Study of the Use of Neoadjuvant Cabazitaxel With Hormonal Treatment in Patients Operable Prostate Cancer, Assess the Efficacy and Toxicity of Cabazitaxel, and Explore Potential Predictive and Prognostic Markers of Clinical Outcome (CHROME)

Prostate Cancer
Jules Bordet Institute

Not yet recruiting

Efficacy of the Mepitel® Film on the Prevention of Radiodermatitis in the Inguinal Fold.

Radiation Toxicity | Radiodermatitis | Radiotherapy Side Effect
University of Sao Paulo General Hospital

Recruiting

Treatment of Patients With Atherosclerotic Disease With Methotrexate-associated to LDL Like Nanoparticles

Coronary Artery Disease | Inflammation | Atherosclerosis

Brazil
Icahn School of Medicine at Mount Sinai

Recruiting

Correlation Vitamin D Level to Endocrine Autoimmune Toxicity Due to Immune Checkpoint Inhibitors

Cancer | Thyroid | PD-1

United States
University of Erlangen-Nürnberg Medical School

Recruiting

Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis

Psoriatic Arthritis | Withdrawal | Reduction

Germany
University of Sao Paulo General Hospital
Hospital Santa Marcelina

Recruiting

Treatment of Patients With Mild Coronavirus-19 (COVID-19) Disease With Methotrexate Associated to LDL Like Nanoparticles (Nano-COVID19) (Nano-COVID19)

Inflammation | Covid19 | Coronavirus

Brazil
Krankenhaus Barmherzige Schwestern Linz
Verein zur Forschungsförderung der Krebshilfe OÖ; RECENDT GmbH; Johannes Kepler... and other collaborators

Recruiting

Optical Coherence Tomography in Patients With Radiotherapy for Head and Neck Cancer (ROOCT)

Head and Neck Cancer | Radiotherapy

Austria

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