Search clinical trials for: pharmacology.

Total 1967 results

Johns Hopkins University

Recruiting

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

Depression | Alzheimer Disease | Depressive Symptoms | Mild Cognitive Impairment

United States
Vigil Neuroscience, Inc.

Enrolling by invitation

A Phase 1 Study of VG-3927 in Healthy Adults

Healthy

United States
Immuron Ltd.
United States Department of Defense; Naval Medical Research Center

Active, not recruiting

Clinical Study to Assess the Efficacy of IMM-124E (Travelan®) in a Controlled Human Infection Model

Diarrhea | Infectious Diarrhea | Travelers Diarrhea

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Reduced Nicotine Cigarette Purchasing Decisions

Tobacco Use Disorder

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Effect of Itraconazole on the Pharmacokinetics of Bardoxolone Methyl in Healthy Adults

Healthy Volunteers

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Pharmacokinetic Study of Omaveloxolone in Healthy Volunteers

Healthy

United States
Takeda
Takeda Development Center Americas, Inc.; Baxalta Innovations GmbH, now part...

Completed

A Study of TAK-881 in Healthy Adults

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide

Obesity | Diabetes Mellitus, Type 2 | Overweight

United States
Chinook Therapeutics, Inc.

Terminated

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CHK-336 in Healthy Volunteers

Healthy Volunteers

United States
Graviton Bioscience Corporation

Completed

Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Dose of GV101 in Healthy Subjects

Phase 1

United States
AstraZeneca

Completed

Study With CIN-107 Following Multiple Oral Ascending Doses in Healthy Subjects

Hypertension

United States
Johns Hopkins University

Completed

Effects of Psilocybin in Anorexia Nervosa

Anorexia Nervosa

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin

Migraine

Belgium
Centre of Clinical Pharmacology, Hanoi Medical...
HK inno.N Corporation; Kyunghee University

Completed

Effect of Red Ginseng Extract on Changes in Indicators of Immune Function in Vietnamese Healthy Volunteers

Healthy

Vietnam
Equilibre Biopharmaceuticals B.V.

Completed

Safety, Tolerability, and Pharmacokinetics of EQU-001 in Healthy Volunteers

Safety Issues

United States
HiFiBiO Therapeutics

Completed

Study to Assess the Safety, Tolerability, and Pharmacokinetics of HFB30132A Against COVID-19 in Healthy Adults

Healthy

United States
Medical University of Vienna

Completed

Investigation of Different Scanning Protocols for 3 Dimensional High-resolution Imaging of the Human Cornea With Optical Coherence Tomography (OCT) - A Pilot Study

Keratoconus | Corneal Neovascularisation

Austria
Concert Pharmaceuticals

Completed

Drug-drug Interaction Study of CTP-543 and Rifampin in Healthy Adult Subjects

Healthy Volunteers

United States
Shire

Completed

The Effect of Food on the Bioavailability of a Single Dose of SSP-004184SS in Healthy Adult Subjects

Healthy

United States
Shire

Completed

Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Recombinant Human C1 Esterase Inhibitor in Healthy Adult Subjects

Hereditary Angioedema (HAE)

United States
Shire

Withdrawn

Pharmacokinetics of Granule and Tablet Formulations of Deferitazole (Disodium Salt) and a Capsule Formulation of Deferitazole (Magnesium Hydroxide Salt)

Healthy

United States
Shield Therapeutics

Unknown

Four-Way Crossover Study to Compare Ferric Maltol Capsules and Oral Suspension in Healthy Volunteers

Anemia, Iron Deficiency

United States
Nucorion Pharmaceuticals, Inc.
Medpace, Inc.; Ligand Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of NCO-48 Fumarate in Healthy Subjects

Hepatitis B

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Reproducibility of Flow Measurements in the SMA Using Doppler Ultrasound

Ultrasound

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.

Pruritus

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.

Pruritus

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick

Pruritus

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick.

Pruritus

Belgium
PegBio Co., Ltd.
Covance

Completed

Dose-finding of PB-119 Administered Subcutaneously Once Weekly Versus Placebo in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)

United States
Eli Lilly and Company
CoLucid Pharmaceuticals; SNBL Clinical Pharmacology Center, Inc.

Completed

Effect of Single Oral Doses of Lasmiditan When Coadministered With Single Oral Doses of Sumatriptan in Healthy Participants

Migraine

United States
Medical University of Vienna

Terminated

Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging

Primary Open Angle Glaucoma | Ocular Hypertension | Normal Tension Glaucoma

Austria
Repros Therapeutics Inc.

Completed

Comparison of Two Formulations of Androxal

Bioequivalence

United States
Allecra

Completed

Single Dose Mass Balance Study With C14 - Labeled AAI101 in Healthy Male Volunteers

Healthy

United States
Syntimmune, Inc.

Completed

A Study of SYNT001 in Healthy Volunteers

Healthy

United States
Central South University

Unknown

Clinical Research on Teratment of Gastrointestinal Cancer in the Preoperative by Propranolol

Gastrointestinal Cancer

China
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation (1207)

Nicotine Dependence

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

Pain | Addiction | Opioid Dependence

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain (1401)

Chronic Pain | Opioid-Related Disorders

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse

Cocaine Dependence

United States
Bial - Portela C S.A.

Completed

Effect of BIA 3-202 on the Pharmacokinetics and Pharmacodynamics of Warfarin

Healthy

Portugal
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Treatment for Caffeine Dependence

Caffeine Use Disorder (DSM-5 Condition for Further Study)

United States
Johns Hopkins University
Pfizer

Completed

Relapse Prevention With Varenicline (0815)

Substance-Related Disorders | Smoking Cessation | Recurrence

United States
Galapagos NV

Completed

This is a Study to Evaluate the Effect of Aging of Multiple Doses of GLPG1205 in Healthy Subjects

Healthy | Elderly

Belgium
Bial - Portela C S.A.

Completed

Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics

Parkinson Disease

Portugal
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study Comparing Salmeterol/Fluticasone Easyhaler and Seretide Diskus

Asthma

Finland
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Improving Learning-based Treatment of Cocaine Dependence With Medication

COCAINE-RELATED DISORDERS

United States
The Alfred

Completed

Digoxin Withdrawal in Stable Heart Failure

Heart Failure

Australia
Noven Therapeutics

Completed

Pharmacokinetic Evaluation of Brisdelle™ (Formerly Known as Mesafem) Following Single & Repeat Oral Administration in Healthy Postmenopausal Women (N30-005)

Postmenopausal Symptoms

United States
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study Comparing Salmeterol/Fluticasone Easyhaler Products and Seretide Diskus

Asthma

Finland
University Medicine Greifswald

Completed

Impact of Two Genetic Variants of OATP1B3 or MRP2 or Rifampin on Systemic Disposition and Biological Efficacy of CCK-8

Gastrointestinal Hormones

Germany

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