Search clinical trials for: Pharmacokinetics Safety Tolerability Pharmacodynamics

Total 50831 results

Cytos Biotechnology AG

Completed

Safety and Immunogenicity of a Melan-A VLP Vaccine in Advanced Stage Melanoma Patients

Malignant Melanoma

Switzerland
Weill Medical College of Cornell University
Forest Laboratories

Terminated

The Efficacy and Safety of Escitalopram for Depression in Multiple Sclerosis

Depression | Multiple Sclerosis

United States
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of a Commercially Available Influenza Vaccine (Formulation 2006/2007) When Administered to Subjects 18 Years of Age or Older

Influenza

Italy
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of Three Commercially Available Influenza Vaccines in Children Aged 6 to <36 Months

Influenza

Finland
Novartis
Novartis Vaccines; Chiron s.r.l. Beijing Representative Office

Completed

Comparative Trial Evaluating Safety and Immunogenicity of an Adjuvanted and a Conventional Influenza Vaccine in Elderly Subjects (> 60 Years)

Influenza

China
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of a Commercially Available Influenza Vaccine (Formulation 2006/2007) When Administered to Elderly Subjects

Influenza

Italy
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of a Inactivated Influenza Vaccine When Administered to Non Elderly Adults and Elderly Subjects.

Influenza Disease

Italy
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of an Adjuvanted Influenza Vaccine in Subjects Aged 65 Years and Over.

Influenza

Italy
Sheltering Arms Physical Rehabilitation Hospitals
Genzyme, a Sanofi Company; Virginia Commonwealth University

Unknown

Synvisc Injections for Lumbar Facet Joint Pain

Joint Pain

United States
Biogen

Terminated

Safety and Efficacy of Zevalin in the Treatment of Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United States
Ain Shams University
National Institute of Allergy and Infectious Diseases (NIAID); Beth Israel... and other collaborators

Completed

Timing and Duration of Acute Hepatitis C Treatment

Hepatitis C

Egypt
Mount Sinai Hospital, Canada

Terminated

Pilot Study to Assess Safety and Feasibility of Resuscitation of Preterm Infants With Controlled Volume of Air/Oxygen

Resuscitation

Canada
NYU Langone Health
Genentech, Inc.

Completed

Efficacy and Safety of Efalizumab in the Treatment of Moderate-Severe Hydradenitis Suppurativa

Hidradenitis Suppurativa

United States
QuatRx Pharmaceuticals Company

Completed

Safety and Efficacy Study of Two Dose Regimens of Becocalcidiol in the Treatment of Plaque-Type Psoriasis

Psoriasis

United States
Korean Gynecologic Oncology Group

Unknown

A Safety and Efficacy of CCRT With Paclitaxel as Adjuvant Therapy to Post-Operative Advanced Endometrial Cancer Patients

Endometrial Cancer

Korea, Republic of
Heidelberg University
Merck KGaA, Darmstadt, Germany

Unknown

Safety Study of Cetuximab, Radiotherapy and Temozolomide in Primary Glioblastoma Multiforme(GERT)

Glioblastoma Multiforme

Germany
Zhejiang University

Unknown

Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension

Idiopathic Pulmonary Arterial Hypertension

China
World Health Organization
University of Cape Town; Hanoi Obstetrics and Gynecology Hospital

Completed

Comparison of the Safety of First Trimester Abortions Performed by Physicians and Non-Physicians in South Africa and Viet Nam.

Abortion, Induced
Abbott

Terminated

A Study of the Safety and Efficacy of Multiple Doses of ABT-089 in Subjects With Alzheimer's Disease

Alzheimer's Disease

United States
Novartis

Completed

Follow-Up Study of Patients Previously Treated With Pimecrolimus Tablets for Atopic Dermatitis

Atopic Dermatitis
Novartis

Completed

Follow-Up Study of Patients Previously Treated With Pimecrolimus Tablets for Chronic Plaque-Type Psoriasis

Psoriasis
St. Luke's Hospital, Pennsylvania

Completed

Effectiveness and Safety Study of Etomidate Versus Midazolam to Help Place a Breathing Tube Outside of the Hospital.

Respiratory Failure

United States
Alizyme

Completed

Efficacy and Safety of ATL-962 in Obese Diabetics

Obesity | Non-Insulin-Dependent Diabetes Mellitus

Finland, Netherlands, Denmark, United Kingdom, Sweden
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Immunogenicity and Safety Study of Pneumococcal 7-Valent Conjugate Vaccine in Sickle Cell Disease Infants.

Pneumococcal Infections

France
National Center for Complementary and Integrative...

Completed

Safety and Effectiveness of Flaxseed for Reducing High Cholesterol

Hypercholesterolemia

United States
Tissue Regeneration Technologies

Unknown

Safety & Efficacy Study for the Use of Extracorporeal Shockwaves in the Treatment of Diabetic Foot Ulcers

Chronic Diabetic Foot Ulcers

United States
Purdue Pharma LP

Terminated

Efficacy and Safety of Hydromorphone Hydrochloride Extended-Release Compared to Placebo in Subjects With Persistent Pain

Chronic Non-Malignant Pain

United States
Abbott

Completed

Safety and Efficacy of Atrasentan in Men With Hormone Naive Prostate Cancer Exhibiting Early Signs of Biochemical Failure

Prostatic Neoplasms

United States, Canada
Abbott

Completed

Safety and Efficacy of Zemplar Capsule in Reducing Serum IPTH Levels in Chronic Kidney Disease Subjects (Three Times Weekly)

Renal Insufficiency, Chronic

United States, Poland
Hadassah Medical Organization

Completed

Efficacy and Safety of a Preparation Containing an Antibiotic and Anti-Inflammatory Agent in Acne Vulgaris

Acne Vulgaris

Israel
Arginox Pharmaceuticals

Terminated

A Study of the Safety and Efficacy of Nitric Oxide Reduction in Patients With Cardiogenic Shock After a Heart Attack

Shock, Cardiogenic

United States, Canada
Abbott

Completed

An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents

Bipolar Disorder

United States
Abbott

Terminated

A Study of the Safety and Efficacy of Depakote Sprinkle Capsules in the Treatment of Partial Seizures in Children

Partial Seizure Disorder

United States
Abbott

Completed

An Inpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder

Bipolar Disorder

United States
Abbott

Completed

Safety and Efficacy of Zemplar Capsule in Reducing Serum iPTH Levels in Chronic Kidney Disease Subjects (Daily Dosing)

Renal Insufficiency, Chronic

United States, Poland
Northfield Laboratories

Unknown

Safety and Efficacy of PolyHeme(R) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-Hospital Setting

Hemorrhagic Shock

United States
Abbott

Completed

Safety and Efficacy of Zemplar Capsule in Reducing Serum iPTH Levels in Chronic Kidney Disease Subjects (Three Times Weekly)

Renal Insufficiency, Chronic

United States, Poland
Abbott

Completed

Safety and Effectiveness of Zemplar Injection in Decreasing iPTH Levels in Pediatric ESRD Subjects on Hemodialysis

End Stage Renal Disease | Secondary Hyperparathyroidism

United States
AstraZeneca

Completed

GLAD: Dose-Finding, Efficacy, and Safety of AZ 242 (Tesaglitazar) in Subjects With Type 2 Diabetes

Type 2 Diabetes

United States, Canada, France, Mexico
Evolutec Group

Unknown

Safety and Efficacy Study of rEV131 in the Treatment of Ocular Inflammation After Cataract Surgery

Ocular Inflammation

United States
Laboratoires Thea

Completed

Study of the Ocular Safety After Repeated Instillations of T1225 1% or 1.5% Eye Drops in Healthy Volunteers

Eye Infections, Bacterial
Abbott

Completed

Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects

HIV Infections

Spain, United Kingdom, United States, France, Australia, Germany, Singapore
Laboratoires Thea

Completed

Efficacy and Safety of T1225 1.5% Versus Tobramycin 0.3 % in the Treatment of Purulent Bacterial Conjunctivitis

Conjunctivitis, Bacterial
Laboratoires Thea

Completed

Efficacy and Safety of 2 Dosing Regimens of T1225 Eye Drops 1.5% Versus Oral Azithromycin in Treatment of Trachoma

Trachoma
Gachon University Gil Medical Center

Completed

Safety and Effects of Ramipril Combined With Candesartan

Hypertension
Laboratoires Thea

Completed

Ocular Pharmacokinetics After a Single Drop Instillation of T1225 0.5, 1, 1.5% in 91 Healthy Volunteers

Eye Infections, Bacterial
Abarbanel Mental Health Center

Completed

Tolerability and Efficacy of High Dose Escitalopram for the Treatment of Obsessive-Compulsive Disorder (OCD)

Obsessive-Compulsive Disorder

Israel
Eli Lilly and Company
Boehringer Ingelheim

Completed

Safety and Effectiveness Study of Duloxetine HCl in Women of Different Backgrounds With Stress Urinary Incontinence Who May Also Have Other Various Medical Conditions.

Stress Urinary Incontinence

United States
Pfizer

Completed

Assessment of Onset, Safety & Toleration of UK-369,003 in Male Erectile Dysfunction

Impotence

United States
Pfizer

Completed

Assessment Of Duration Of Action, Safety & Toleration Of UK369,003 and Cialis In Patients With Erectile Dysfunction

Impotence

3

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