Clinical Trials Sponsored by Concert Pharmaceuticals

Total 51372 results

Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801) (1703/1801)

Lymphoma | Acute Leukemia | Myelodysplasia | Chronic Myelogenous Leukemia (CML)

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

Sickle Cell Disease

United States
John Mascarenhas
National Cancer Institute (NCI); National Institutes of Health (NIH); Celgene... and other collaborators

Completed

Combined Ruxolitinib and Enasidenib in Patients With Accelerated/Blast-phase Myeloproliferative Neoplasm or Chronic-phase Myelofibrosis With an IDH2 Mutation

IDH2 Mutation | Accelerated/Blast-phase Myeloproliferative Neoplasm | Chronic-phase Myelofibrosis

United States, Canada
Leiden University
Cancer Research UK; NCIC Clinical Trials Group; Mario Negri Institute for Pharmacological... and other collaborators

Active, not recruiting

Randomized Trial of Radiation Therapy With or Without Chemotherapy for Endometrial Cancer (PORTEC-3)

Endometrial Cancer

Netherlands
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Terminated

Autologous or Donor Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma (BMT CTN 0202)

Follicular Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Peripheral Blood Stem Cell Transplant vs Bone Marrow Transplant in Individuals With Hematologic Cancers (BMT CTN 0201)

Leukemia | Myeloproliferative Disorders | Myelodysplastic-Myeloproliferative Diseases

United States, Canada
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101)

Lymphoma | Leukemia | Infection

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Autologous Transplant in HIV Patients (BMT CTN 0803)

Lymphoma | HIV

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Blood Stem Cell Transplant With Low Dose Chemotherapy for Relapsed Follicular Non-Hodgkin's Lymphoma (BMT CTN 0701)

Lymphoma, Non-Hodgkin

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) (RICHI)

Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Leukocyte Adhesion Deficiency | Chronic Active Epstein-Barr Virus Infection | HIGM-1 | IPEX

United States, Canada
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Easy-to-Read Informed Consent (ETRIC) for Hematopoietic Cell Transplantation Clinical Trials (BMT CTN 1205)

Improve the Informed Consent Process

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Exercise and Stress Management Post Autologous and Allogeneic Transplant (BMT CTN 0902)

Physiological Stress

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

Severe Aplastic Anemia

United States
University of Nottingham
Cardiff University; University College, London; The Leeds Teaching Hospitals... and other collaborators

Completed

Yorkshire Enhanced Stop Smoking Study (YESS)

Heart Diseases | Respiratory Disease | Cancer, Lung

United Kingdom
Fred Hutchinson Cancer Center
Palo Alto Veterans Institute for Research; Bedford Research Corporation, Inc.; Jefferson Center, Community Mental Health Clinic and other collaborators

Completed

Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder (WebQuit Plus)

Smoking | Bipolar Disorder

United States
Maisonneuve-Rosemont Hospital
Canadian Institutes of Health Research (CIHR); Hopital de l'Enfant-Jesus; St.... and other collaborators

Completed

Expanded Cord Blood in Patients in Need of an Allogeneic Stem Cell Transplant

Hematologic Malignancy

Canada
National Cancer Institute (NCI)
Centers for Disease Control and Prevention; National Institute for Occupational...

Completed

A Case-Referent Study of Brain Tumors in Adults

Brain Tumors

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI); National Institute of Arthritis and Musculoskeletal... and other collaborators

Completed

Women's Health Initiative (WHI)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Breast Neoplasms | Bone Diseases | Osteoporosis | Colonic Neoplasms | Postmenopause
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Wyeth is now a wholly owned subsidiary of... and other collaborators

Completed

CCI-779 in Treating Patients With Advanced Solid Tumors

Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
Brigham and Women's Hospital
National Cancer Institute (NCI); University Hospitals Cleveland Medical Center and other collaborators

Completed

Personalized Asthma Care Team (PACT)

Obesity | Asthma | Sleep Disordered Breathing
Children's Cancer Group, China
Xiangya Hospital of Central South University; Qilu Hospital of Shandong University and other collaborators

Recruiting

Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma (T-LBL)

T-cell Lymphoblastic Lymphoma

China
Medical University of Vienna
M.D. Anderson Cancer Center; Odense University Hospital; Radboud University Medical... and other collaborators

Recruiting

Image Guided IMRT, Radiochemotherapy and MRI-based IGABT in Locally Advanced Cervical Cancer (EMBRACEII)

Uterine Cervical Neoplasms

Austria
Children's Hospital of Philadelphia
Eli Lilly and Company; University of Pennsylvania; Takeda; National Institute of... and other collaborators

Recruiting

The Myelin Disorders Biorepository Project (MDBP)

Mucopolysaccharidoses | Leukoencephalopathies | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2... and other conditions

United States
Institut National de la Santé Et de la Recherche...
UPCET; PARTNERS for International clinical Research; European Fundation for the... and other collaborators

Active, not recruiting

Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen (TREOCAPA)

Acetaminophen | Patency of the Ductus Arteriosus | Extreme Prematurity

France, Norway, Belgium, Estonia, Ireland, Switzerland, Sweden, Denmark, Finland, Hungary, Italy, Portugal
Radboud University Medical Center
Maastricht University Medical Center; Erasmus Medical Center; Catharina Ziekenhuis... and other collaborators

Recruiting

PROMOTE Study: Prediction of Response Of HorMOnal Treatment in Advanced and Recurrent Endometrial Cancer (PROMOTE)

Endometrial Cancer Recurrent | Endometrial Cancer Stage III | Endometrial Cancer Stage IV

Netherlands
Foundation for the National Institutes of Health
M.D. Anderson Cancer Center; Eli Lilly and Company; National Institute of Diabetes... and other collaborators

Unknown

Prospective Observational Study to Evaluate Biomarkers of Aminoglycoside Nephrotoxicity in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
Marian Neuhouser
Duke University; University of Washington; University of Nebraska; United States...

Recruiting

Phase 1 Seattle Dietary Biomarkers Development Center (P1-SDBDC)

Healthy Adults

United States
Prof.dr. H.P. Beerlage
Radboud University Medical Center; Amsterdam UMC, location VUmc; The Netherlands... and other collaborators

Recruiting

PSA Glycomics Assay for Early Detection of Prostate Cancer

Prostate Cancer | PSA

Netherlands
Helse Stavanger HF
University Hospital of North Norway; Sorlandet Hospital HF; St. Olavs Hospital; University Hospital, Akershus and other collaborators

Terminated

"Watch and Wait" After Neo-adjuvant Chemoradiotherapy for Primary Locally Advanced Rectal Cancer. (NORWAIT)

Rectal Cancer

Norway
Memorial Sloan Kettering Cancer Center
University of Southern California; Weill Medical College of Cornell University and other collaborators

Active, not recruiting

Early Onset and Familial Gastric Cancer Registry

Gastric Cancer

United States, Nigeria
National Institutes of Health Clinical Center (CC)
Harvard Medical School (HMS and HSDM); National Cancer Institute (NCI); National... and other collaborators

Completed

Hospital COVID-19 Surge and Associated Mortality Risk

Volume Outcome Relationship Among COVID-19 Inpatients in US Hospitals

United States
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Survey Study (MCSIO) (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United States, United Kingdom, Germany
SYZ Cell Therapy Co..
Sun Yat-sen University; Fujian Cancer Hospital; Beijing 302 Hospital; Nanfang Hospital... and other collaborators

Suspended

Multiple Antigen Specific Cell Therapy (MASCT) for Hepatocellular Carcinoma(HCC) Patients After Radical Resection or Radio Frequency Ablation(RFA). (HCC DC CTL)

Hepatocellular Carcinoma

China
Fred Hutchinson Cancer Center
Johns Hopkins University; University of Washington; Cedars-Sinai Medical Center; VA Puget Sound Health Care System and other collaborators

Completed

Effects of Sulforaphane on Normal Prostate Tissue (PHASE)

Prostate Cancer

United States
Peking Union Medical College Hospital
Henan Cancer Hospital; Shengjing Hospital; Sun Yat-Sen Memorial Hospital of Sun... and other collaborators

Recruiting

Toripalimab Plus Actinomycin-D as Fist-Line Treatment for GTN With FIGO Score 5-6 (TA56)

Gestational Trophoblastic Neoplasia

China
Fudan University
Chongqing University Cancer Hospital; Sun Yat-sen University; Peking University... and other collaborators

Recruiting

SNF Platform Study of HR+/ HER2-advanced Breast Cancer

Breast Cancer | Advanced Breast Cancer | Breast Neoplasm | HER2-negative Breast Cancer | Hormone Receptor Positive Tumor

China
National Cancer Centre, Singapore
National University Hospital, Singapore; Singapore General Hospital; Tan Tock... and other collaborators

Recruiting

Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma (EMPHASIS)

Hepatocellular Carcinoma

Singapore
ThermoMind Ltd.
M.D. Anderson Cancer Center; Technion, Israel Institute of Technology; Sheba... and other collaborators

Recruiting

ThermoBreast - Non-contact Breast Cancer Imaging Using AI-enhanced Thermography. (ThermoBreast)

Breast Cancer

Germany
Peking Union Medical College Hospital
Henan Cancer Hospital; Shengjing Hospital; Sun Yat-Sen Memorial Hospital of Sun... and other collaborators

Not yet recruiting

Toripalimab Plus Actinomycin-D as Fist-Line Treatment for GTN With FIGO Score 7 (TA7)

Gestational Trophoblastic Neoplasia

China
Tongji Hospital
Shanxi Province Cancer Hospital; Chongqing University Cancer Hospital; Fudan... and other collaborators

Not yet recruiting

Comparing Laparoscopic and Open Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas (NPPC)

Periampullary Adenocarcinoma

China
RenJi Hospital
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Recruiting

Safety of Laparoscopic Resection for Gastrointestinal Stromal Tumor on Unfavorable Anatomic Site of Stomach

Gastrointestinal Stromal Tumors

China
Massachusetts General Hospital
National Cancer Institute (NCI); Mayo Clinic; University of Pennsylvania; Washington... and other collaborators

Active, not recruiting

Proton Therapy vs. IMRT for Low or Intermediate Risk Prostate Cancer (PARTIQoL)

Prostate Cancer

United States
European Society for Blood and Marrow Transplantation
European Organisation for Research and Treatment of Cancer - EORTC; Swiss Group... and other collaborators

Terminated

HCT Versus CT in Elderly AML

Acute Myeloid Leukemia

Switzerland, Netherlands, Germany, France, Australia, Austria, Belgium
University Medical Center Groningen
Radboud University Medical Center; Maastricht University Medical Center; Erasmus... and other collaborators

Recruiting

Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels (ADAPT ALEC)

Carcinoma, Non-Small-Cell Lung | Lung Cancer | Drug Monitoring | Anaplastic Lymphoma Kinase Gene Mutation | Anaplastic Lymphoma Kinase Gene Translocation

Netherlands, France
The Netherlands Cancer Institute
Karolinska Institutet; Radboud University Medical Center; University Medical... and other collaborators

Recruiting

EffectiveNess of a Multimodal preHAbilitation Program in patieNts With Bladder canCEr Undergoing Cystectomy (ENHANCE)

Bladder Carcinoma

Netherlands
Sun Yat-sen University
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; First People's Hospital... and other collaborators

Not yet recruiting

Sintilimab Combined With Chemotherapy and Radiotherapy in Newly Diagnosed Metastatic Nasopharyngeal Carcinoma: A Multicenter Study

Nasopharyngeal Carcinoma

China
University College, London
King's College London; Rambam Health Care Campus; University of Melbourne; Menzies... and other collaborators

Not yet recruiting

18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in S. Aureus Bacteraemia (PET-SAB)

Sepsis | Staphylococcus Aureus Infection | Bloodstream Infection | Staphylococcus Aureus Bacteremia | Sepsis Bacterial | Staphylococcus Aureus Septicemia | Staph Sepsis
Guang'anmen Hospital of China Academy of Chinese...
West China Hospital; Jiangsu Cancer Institute & Hospital; Nanjing University... and other collaborators

Recruiting

Acupuncture Versus Sham Acupuncture or Usual Care for Antiandrogen-Induced Hot fLashes in Prostate Cancer (AVAIL) (AVAIL)

Hot Flashes | Prostate Cancer | Acupuncture

China
National Cancer Centre, Singapore
Nanyang Technological University; Duke-NUS Graduate Medical School; MiRXES Pte... and other collaborators

Recruiting

Early Detection of Hepatocellular Carcinoma in a High-risk Prospective Cohort (ELEGANCE)

Liver Diseases

Singapore
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine; The Faris Foundation and other collaborators

Recruiting

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

High Grade Glioma | Diffuse Intrinsic Pontine Glioma | Embryonal Tumor | Ependymal Tumor

United States

Clinical Trials Sponsored by Concert Pharmaceuticals

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