Search clinical trials for: cytochrome P4503A4

Total 5682 results

Santen Inc.
Vistakon Pharmaceuticals

Terminated

Ocular Penetration of 1.5% Levofloxacin and 0.5% Moxifloxacin During Corneal Transplant Surgery

Corneal Transplantation

United States
University of Virginia
National Cancer Institute (NCI)

Unknown

Modafinil in Treating Fatigue in Patients With Cancer

Depression | Fatigue | Unspecified Adult Solid Tumor, Protocol Specific | Cognitive/Functional Effects

United States
North Suffolk Mental Health Association
Cephalon

Completed

A Placebo-Controlled Trial of Modafinil (Provigil) Added to Clozapine in Patients With Schizophrenia

Schizophrenia

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Rifampin on Single-dose Pharmacokinetics of HCV-796

Healthy
National Institute of Allergy and Infectious Diseases...

Completed

Nevirapine (NVP) Use to Prevent Mother-to-Child Transmission of HIV

HIV Infections

Ethiopia
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Oxcarbazepine Oral Suspension 300 mg/5mL Under Fed Condition

Healthy

India
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Oxcarbazepine Oral Suspension 300 mg/5 mL Under Fasting Conditions

Healthy

India
Govind Ballabh Pant Hospital
Jhaver Research Foundation Limited

Completed

Evaluation of Safety & Efficacy of Synbiotic on the Incidence and Recurrence of Spontaneous Bacterial Peritonitis (SBP) in Cirrhotics

Cirrhosis With Ascites

India
University Hospital, Geneva
Swiss HIV Cohort Study

Unknown

Adjusting Antiretroviral Therapy Dosage Using Therapeutic Drug Monitoring (TDM)

HIV Infections | Human Immunodeficiency Virus

Switzerland
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Ketoconazole on Single-Dose Pharmacokinetics of HCV-796

Healthy
The Center for Autism and Related Disorders
The International Child Development Resource Center; Thoughtful House

Unknown

Study of Fluconazole in Children With Autism Spectrum Disorder

Autism Spectrum Disorder

United States
Universita di Verona

Completed

Time-Effect of Montelukast Protection (TEMPE)

Asthma | Exercise-Induced Asthma

Italy
University of Helsinki
Merck Sharp & Dohme LLC

Completed

The Effect of Montelukast Treatment in Wheezy Infants (Montelukast)

Signs and Symptoms, Respiratory | Lung Disease, Obstructive

Finland
Bayer

Completed

Efficacy and Safety of CIPRO XR Versus CIPRO IR in Patients With Complicated Urinary Tract Infections (EMERON)

Urinary Tract Infection

Italy
Bayer

Completed

Study To Evaluate The Efficacy And Safety Of Ciprofloxacin Extended-Release (Cipro® XR) 1000 mg Tablets Given Once Daily For 7 To 14 Days In The Treatment Of Patients 18 Years Or Older With Complicated Urinary Tract Infections Caused By Pseudomonas Aeruginosa And Other Common Uropathogens

Urinary Tract Infections

United States
Kirby Institute
Hoffmann-La Roche

Completed

A 48-Week, Randomised, Study to Describe the Pharmacokinetic Profile and Durability of Atazanavir-Saquinavir-Ritonavir Once Daily and Describe the Pharmacokinetic Profile of Saquinavir-Ritonavir Using Saquinavir 500mg Formulation: the ASK-500 Study (ASK-500)

HIV Infections

Australia
Korean College of Helicobacter and Upper Gastrointestinal...

Unknown

H. Pylori Eradication on Healing of Iatrogenic Gastric Ulcer by Endoscopic Mucosal Resection

Ulcer

Korea, Republic of
University Medical Center Groningen

Completed

Withdrawal Versus Continuation of Amiodarone in Successfully Treated Patients With Persistent Atrial Fibrillation (WISDOM)

Persistent Atrial Fibrillation

Netherlands
National Institute of Mental Health (NIMH)

Completed

Treatment of Youth With ADHD and Anxiety

Generalized Anxiety Disorder | Attention Deficit Hyperactivity Disorder | Social Phobia | Anxiety, Separation

United States
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Drug Interaction Study With Atazanavir/Ritonavir and Atazanavir

Healthy Volunteer

United States
MerLion Pharmaceuticals GmbH

Completed

Finafloxacin 300 mg Twice a Day (b.i.d.) Versus Ciprofloxacin 250 mg Twice a Day (b.i.d) in Patients With Lower Uncomplicated UTI (uUTI) (FLUT)

Urinary Tract Infections

Singapore, Germany
Hvidovre University Hospital

Completed

Effect of Add-on Montelukast to Inhaled Corticosteroids on Airway Responsiveness (SINGDEN)

Asthma
InterMune

Completed

Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Peru
Marywood University

Completed

Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?

Airway Inflammation

United States
North Suffolk Mental Health Association

Completed

Nicotine Replacement Therapy for Smoking Cessation in Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
French National Agency for Research on AIDS and...

Completed

Efficacy of Paroxetine in the Prevention of Depressive Syndrome in Patients With Chronic Hepatitis C Treated by PEG-Interferon Alfa Plus Ribavirin

Chronic Hepatitis C

France
Louisiana State University Health Sciences Center...
GlaxoSmithKline

Completed

Lamotrigine Augmentation in Resistant Depression

Unipolar Depression

United States
Korean Epilepsy Society
GlaxoSmithKline

Completed

Lamotrigine Cognitive Function Study in Adult Untreated Epilepsies

Epilepsy

Korea, Republic of
Brigham and Women's Hospital

Completed

The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction

Sleep Restriction | Impaired Glucose Metabolism

United States
Gyeongsang National University Hospital

Unknown

Comparison of Platelet Inhibition With Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel According to Hepatic Cytochrome 2C19 Allele (CYP2C19) Polymorphism (ACCEL2C19)

Coronary Artery Stenosis | Maximal Platelet Aggregation | Late Platelet Aggregation | High Post-Treatment Platelet Reactivity

Korea, Republic of
Javelin Pharmaceuticals

Completed

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Hepatic Insufficiency | Healthy | Renal Insufficiency, Chronic

United States, United Kingdom
Zodiac Produtos Farmaceuticos S.A.

Unknown

Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis

Candidiasis | Bacterial Vaginosis

Brazil
Kansas City Veteran Affairs Medical Center
Sanofi

Unknown

Neoadjuvant Therapy With Docetaxel and Ketoconazole in Patients With High-Risk Prostate Cancer: A Pilot Study (IST 16167)

Prostate Cancer

United States
Sanofi

Completed

Efficacy and Safety of One Single Dose of SR58611 Compared to Placebo and Paroxetine

Major Depressive Disorders

United States
Sanofi

Completed

Efficacy and Safety of SR58611 Compared to Placebo and Paroxetine

Major Depressive Disorders

France, Netherlands, Bulgaria, Estonia, Serbia, Czech Republic, Croatia, Montenegro
AstraZeneca

Completed

Pulmicort Respules(Budesonide Inhalation Suspension) vs Singulair, Children

Asthma
Virginia Commonwealth University
University of Louisville

Completed

Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

Sleep Apnea

United States
AstraZeneca

Completed

DESOLO - SiT Peri-Launch: A Comparison of Symbicort Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma in Adults

Asthma

Germany
Pfizer
Mclean Hospital

Completed

Assessment of Voriconazole Penetration Into the Brain by Fluorine-Magnetic Resonance Spectroscopy

Fungal Infection
Beijing Hospital

Unknown

Efficacy and Safety Trial to Assess Moxifloxacin in Treating Community-Acquired Pneumonia (CAP) With Aspiration Factors

Community-Acquired Pneumonia

China
Assaf-Harofeh Medical Center

Unknown

Use of Pharmacogenetics in the Treatment of Children With Autistic Spectrum Disorders

Autism | Neuroleptic Treatment

Israel
University of Auckland, New Zealand
Counties Manukau Health; Auckland Medical Research Foundation; Auckland District... and other collaborators

Unknown

Cyclophosphamide in Lupus Nephritis

Systemic Lupus Erythematosus

New Zealand
Sanofi

Completed

MDR TB, Levofloxacin, Multi-Drug-Resistant Pulmonary Tuberculosis

Tuberculosis, Pulmonary

Russian Federation
US Department of Veterans Affairs
Eli Lilly and Company

Completed

Fluoxetine as a Quit Smoking Aid for Depression-Prone Smokers

Depression | Smoking

United States
Veterans Medical Research Foundation
Cephalon

Completed

Modafinil Augmentation Therapy for Excessive Daytime Sleepiness and Negative Symptoms in Patients With Schizophrenia

Schizophrenia

United States
GlaxoSmithKline

Completed

Co-Administration Of Fosamprenavir With Methadone: A Drug Interaction Study.

Healthy Subjects

United States
Abbott

Completed

A Study of ABT-378/Ritonavir Combination in HIV-Infected Patients Who Have Taken Protease Inhibitors

HIV Infections

United States
Abbott

Completed

A Study to Compare Two Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Previously Received Anti-HIV Treatment

HIV Infections

United States, Canada, Switzerland, France, Germany, United Kingdom, Brazil, Austria, Australia, Denmark, Poland, South Africa, Spain, Puerto Rico
Abbott

Completed

A Study of Ritonavir (ABT-538) When Used With Nelfinavir in HIV-Infected Patients

HIV Infections

United States
Abbott

Completed

A Study of Ritonavir/Indinavir Combination in HIV-Infected Patients

HIV Infections

United States

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