Clinical Trials Sponsored by Insmed Incorporated

Total 1694 results

Bausch & Lomb Incorporated

Completed

Corneal Endothelial Cell Density in Eyes Treated With a Fluocinolone Acetonide Intravitreal Implant

Uveitis, Posterior

United States
Bausch & Lomb Incorporated

Terminated

A Study to Evaluate Plasmin for the Creation of a Posterior Vitreous Detachment (PVD)

Vitreoretinal Traction Syndrome

United States
Bausch & Lomb Incorporated

Completed

Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.

Cataract

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of Tezacaftor (VX-661) in Combination With Ivacaftor (VX-770) in Subjects Aged 12 Years and Older With Cystic Fibrosis (CF), Who Have One F508del-CFTR Mutation and a Second Mutation That Has Been Demonstrated to be Clinically Responsive to Ivacaftor

Cystic Fibrosis

United States, Australia, Canada, United Kingdom, Germany, Belgium, Austria, Ireland, Italy, France
Bausch & Lomb Incorporated

Completed

Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension (LUNAR)

Ocular Hypertension | Open-Angle Glaucoma

United States
Bausch & Lomb Incorporated

Completed

Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension (APOLLO)

Ocular Hypertension | Open-Angle Glaucoma

United States
Bausch & Lomb Incorporated

Completed

BOL-303259-X With Timolol 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Constellation)

Ocular Hypertension | Open Angle Glaucoma

United States
Sound Pharmaceuticals, Incorporated

Unknown

A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing Loss (PANIHL)

Noise Induced Hearing Loss

United States
Bausch & Lomb Incorporated

Completed

Study Comparing the Safety and Efficacy of BOL-303259-X to Latanoprost in Subjects With Glaucoma or Ocular Hypertension (Voyager)

Intraocular Pressure

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutation

Cystic Fibrosis

United States, Australia, Canada, Germany, Switzerland, Israel, Netherlands, Belgium, Italy, United Kingdom, France
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, Canada, France, Spain, Israel, Australia, Austria
Neograft Technologies, Incorporated

Completed

The Angioshield Study Feasibility II

Coronary Artery Disease

Lithuania
Bausch & Lomb Incorporated

Completed

Efficacy of Latanoprostene Bunod in Lowering Intraocular Pressure in Japanese Healthy Male Volunteers (KRONUS)

Intraocular Pressure

United States
Torax Medical Incorporated

Completed

LINX Reflux Management System Clinical Study Protocol

Gastroesophageal Reflux

United States, Netherlands
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

Cystic Fibrosis

United States, Canada, Germany, United Kingdom
Cook Group Incorporated

Completed

Zenith(R) Low Profile AAA Endovascular Graft Clinical Study

Abdominal Aortic Aneurysms | Aorto-iliac Aneurysms | Iliac Aneurysms

United States, China, Germany, Sweden, Russian Federation
GlycoMimetics Incorporated
Celerion

Completed

A Study to Evaluate the PK, Safety and Tolerability of GMI-1271 With and Without Filgrastim in Healthy Adult Subjects

Healthy Volunteers

United States
Cook Group Incorporated

Completed

Antimicrobial Hernia Repair Device Clinical Study (AMEX)

Ventral Hernia | Incisional Hernia

Canada, United Kingdom
Castle Biosciences Incorporated

Terminated

Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein Expression Assays

Anal Squamous Cell Carcinoma | Rectal Adenocarcinoma | Anal Adenocarcinoma

United States
Cook Group Incorporated

Completed

Pilot Safety Study of Injectable SIS for Critical Limb Ischemia (CLIC)

Peripheral Arterial Disease | Peripheral Vascular Disease | Critical Limb Ischemia

Czechia
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Belgium, Australia, Denmark, Canada, Sweden
Torax Medical Incorporated

Terminated

RELIEF Europe Study

Obesity | Gastroesophageal Reflux Disease | GERD | Laparoscopic Sleeve Gastrectomy | LSG

Germany, Italy
Cook Group Incorporated

Completed

Evolution® Biliary Stent System-Fully Covered

Carcinomas/Neoplasms

Canada, United States, France, Netherlands
Vertex Pharmaceuticals Incorporated

Completed

Study of Lumacaftor in Combination With Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, Canada
Cook Group Incorporated

No longer available

PRESERVE-Zenith® Iliac Branch System Clinical Extended Study

Aorto-iliac Aneurysms | Iliac Aneurysms

United States
Neograft Technologies, Incorporated

Completed

Angioshield First-In-Human Study to Demonstrate the Preliminary Safety and Efficacy

Coronary Artery Disease

Poland
Cook Group Incorporated

Completed

Zenith(R) Fenestrated Abdominal Aortic Aneurysm (AAA) Endovascular Graft Clinical Study

Abdominal Aortic Aneurysms | Aorto-iliac Aneurysms | Juxtarenal Aneurysms

United States
Cook Group Incorporated

Completed

Cook Micronized Small Intestinal Submucosa (SIS) for Critical Limb Ischemia

Ischemia | Peripheral Arterial Disease | Peripheral Vascular Diseases

Canada
Cook Group Incorporated

Completed

Evaluation of the Zilver® Vena™ Venous Stent (VIVO EU)

Iliofemoral Venous Outflow Obstruction

Switzerland, United Kingdom, Ireland, Germany, Spain
Vertex Pharmaceuticals Incorporated

Completed

A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation (TRANSPORT)

Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

United States, France, Spain, Belgium, Canada, Austria, Australia, Germany, United Kingdom, Denmark
Sound Pharmaceuticals, Incorporated

Completed

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

Cancer | Hearing Loss

United States
Cook Group Incorporated

Completed

Evaluation of the Cook Biodesign® Nipple Reconstruction Cylinder (NRC) (NRC)

Breast Cancer | Breast Reconstruction | Nipple Reconstruction

United States
Inflamax Research Incorporated

Completed

Irritation and Sensitization Potential of Repeat Applications of Rotigotine Patch

Bioequivalence - Irritation and Sensitization Potential of Transdermal Patch

United States, Canada
Cook Group Incorporated

Completed

Zilver PTX Drug-Eluting Peripheral Stent Study

Peripheral Arterial Disease

Germany, Switzerland
Cook Group Incorporated

Completed

Clinical Evaluation of the Surgisis Biodesign Vesico-Vaginal Fistula Plug (VVP)

Vesico-vaginal Fistula

Uganda
Cook Group Incorporated

Completed

Zilver® Flex™ Vascular Stent Study

Peripheral Arterial Disease (PAD)

Germany
Vertex Pharmaceuticals Incorporated

Completed

A Phase 2/3 Open-label Extension Study to Evaluate Long-Term Safety and Efficacy With VX-509 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Estonia, Lithuania, South Africa
Vertex Pharmaceuticals Incorporated

Completed

24-week Study With Open Label Extension of VX-509, an Oral JAK3 Inhibitor, in Subjects Taking Methotrexate

Rheumatoid Arthritis

United States, Argentina, Bulgaria, Czech Republic, Estonia, Germany, Hungary, Mexico, Poland, Romania, Russian Federation, Serbia, Slovakia, Ukraine
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Australia, New Zealand, Belgium
Vertex Pharmaceuticals Incorporated

Terminated

Telaprevir, Peg-IFN-alfa-2a, and RBV in Treatment-Experienced Black/African American and Non-Black/African American Subjects With Genotype 1 Chronic Hepatitis C

Hepatitis C

United States
Cook Group Incorporated

Terminated

Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD) (GERD)

Dyspepsia | Gastroesophageal Reflux Disease | Heartburn | Regurgitation

United States
Vertex Pharmaceuticals Incorporated

Terminated

An Open Label Study of the Effect of Telaprevir in Combination With Ribavirin and Peginterferon on HCV Infection in Stable Liver Transplant Patients

Hepatitis C

Canada, United States
Vertex Pharmaceuticals Incorporated

Completed

Pilot Study Testing the Effect of Ivacaftor on Lung Function in Subjects With Cystic Fibrosis and Residual CFTR Function

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 2 Study to Evaluate the Safety and Efficacy of VX-135 With Ribavirin in Treatment-Naïve Subjects With Chronic Hepatitis C

Chronic Hepatitis C

United States
Bausch & Lomb Incorporated

Completed

Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery

Cataract

United States
Bausch & Lomb Incorporated

Completed

A Study to Determine if 0.6% ISV-403 is Safe and Effective in the Treatment of Bacterial Conjunctivitis.

Acute Bacterial Conjunctivitis
Bausch & Lomb Incorporated

Completed

Safety and Efficacy of a Bausch & Lomb Multipurpose Solution When Compared to Ciba Vision Aquify Multipurpose Solution

Contact Lens Solutions

United States
Cook Group Incorporated

Completed

Zenith® AAA Endovascular Graft Clinical Study

Abdominal Aortic Aneurysm
Bausch & Lomb Incorporated

Completed

One-Day Dispensing Clinical Evaluation of SofLens Daily Disposable Lenses Compared to a Marketed 1 Day Contact Lens

Myopia

United States
Cook Group Incorporated

Completed

Surgisis Anal Fistula Plug Study: An Experience in Saudi Arabia (SurgiSIS AFP)

Anal Fistula

Saudi Arabia

Clinical Trials Sponsored by Insmed Incorporated

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