Clinical Trials Sponsored by Portola Pharmaceuticals

Total 20745 results

Arena Pharmaceuticals

Completed

A Study to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Atopic Dermatitis (ADVISE)

Atopic Dermatitis

United States, Australia, Canada
Primus Pharmaceuticals

Completed

Efficacy of Flavocoxid 500 mg Compared With Naproxen 500 mg in Subjects With Moderate-severe Osteoarthritis of the Knee

Osteoarthritis of Knee
CStone Pharmaceuticals

Completed

A Study of CS1001 in Subjects With Relapsed or Refractory Classical Hodgkin Lymphoma

Hodgkin Lymphoma

China
Regeneron Pharmaceuticals

Completed

Study to Assess the Efficacy of Anti-Bet v 1 Monoclonal Antibodies in Adults to Reduce Symptoms of Seasonal Allergic Rhinitis

Conjunctivitis | Allergic Rhinitis

United States, Belgium, Canada, Denmark, Germany
Botanix Pharmaceuticals

Completed

Study of the Safety, Tolerability and Efficacy of BTX 1204 in Patients With Moderate Atopic Dermatitis

Atopic Dermatitis

United States, Australia, New Zealand
Jazz Pharmaceuticals

Completed

Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

France, United States, United Kingdom, Poland
Endo Pharmaceuticals

Completed

CCH Treatment of Cellulite in the Presence of Dermal Laxity With Comparison Between Two (2) Different Injection Techniques

Laxity; Skin | Cellulite | Edematous Fibrosclerotic Panniculopathy

United States
Catabasis Pharmaceuticals

Completed

Phase 1/2 Study in Boys With Duchenne Muscular Dystrophy (MoveDMD®)

Muscular Dystrophy, Duchenne

United States
Jazz Pharmaceuticals

Terminated

Safety and Tolerability of Cannabidivarin (CBDV) in Children and Young Adults With Autism Spectrum Disorder

Autism Spectrum Disorder

United States
Jazz Pharmaceuticals

Completed

Phase 3 Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms: Open-label Extension Phase (GWPCARE7)

Infantile Spasms

United States, Poland
Jazz Pharmaceuticals

Withdrawn

Investigation of Cognitive Outcomes With Cannabidiol Oral Solution (EPI-COG)

Lennox-Gastaut Syndrome
Concert Pharmaceuticals

Completed

Study to Evaluate Multiple Doses of Fluconazole, a CYP3A4 and CYP2C9 Inhibitor, on the Pharmacokinetics of CTP-543 in Healthy Subjects

Health Volunteers

United States
Intercept Pharmaceuticals

Completed

Phase 2 Study on Effects of Obeticholic Acid (OCA) on Lipoprotein Metabolism in Participants With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
Syndax Pharmaceuticals

Completed

Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC

Carcinoma, Non-Small Cell Lung | Non-Small-Cell Lung Carcinoma

United States
Regeneron Pharmaceuticals

Completed

Phase 1B Study Evaluating Alternative Routes of Administration of CMP-001 in Combination With Pembrolizumab in Participants With Advanced Melanoma

Malignant Melanoma

United States
Arrowhead Pharmaceuticals

Completed

Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

United States
Syndax Pharmaceuticals

Terminated

A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19

COVID | ARDS | Coronavirus | Cytokine Storm | Cytokine Release Syndrome

United States
Aerie Pharmaceuticals

Completed

A Phase 2b Study Evaluating the Safety and Efficacy of AR-15512 Ophthalmic Solution for the Treatment of Dry Eye Disease (COMET-1)

Dry Eye Disease

United States
Concert Pharmaceuticals

Completed

Study To Evaluate The Effect Of Multiple Doses of CTP-543 On The Pharmacokinetics Of Single Doses of Midazolam In Healthy Subjects

Health Volunteers

United States
Concert Pharmaceuticals

Completed

Study to Evaluate the Safety and Efficacy of CTP-543 in Adults With Moderate to Severe Alopecia Areata

Alopecia Areata

United States
Algernon Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of NP-120 on Idiopathic Pulmonary Fibrosis and Its Associated Cough

Idiopathic Pulmonary Fibrosis

Australia, New Zealand
Neurotech Pharmaceuticals

Terminated

Study of the Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology (ECT) for the Treatment of Recurrent Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)

Macular Degeneration

United States, Israel
Bellicum Pharmaceuticals

Active, not recruiting

Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia

United States
Bellicum Pharmaceuticals

Active, not recruiting

Safety/PK Study of Gene Modified Donor T Cell Infusion in Children With Recurrent Hem Malignancies After Allo Transplant

Hematologic Malignancy

Italy
Bellicum Pharmaceuticals

Active, not recruiting

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Anemia, Aplastic | Primary Immune Deficiency Disorder | Cytopenia | Osteopetrosis | Leukemia, Acute Myeloid (AML), Child | Hemoglobinopathy in Children

United States
Dizal Pharmaceuticals

Terminated

Assess the Safety, Tolerability, PK and Anti-tumor Efficacy of DZD2269 in Patients With MCRPC

Metastatic Castration Resistant Prostate Cancer

United States, Korea, Republic of
Allena Pharmaceuticals

Terminated

Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria (URIROX-2)

Enteric Hyperoxaluria

United States, Spain, United Kingdom, Portugal, Romania, Canada, Austria, Belgium, Brazil, Croatia, France, Germany, Italy, Mexico, Russian Federation, Switzerland
Alnylam Pharmaceuticals

Completed

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Polyneuropathy | Hereditary Transthyretin-mediated (ATTRv) Amyloidosis

United States
Woolsey Pharmaceuticals

Active, not recruiting

Rho Kinase (ROCK) Inhibitor in Tauopathies - 1 (ROCKIT-1)

Progressive Supranuclear Palsy | Corticobasal Syndrome

United States
Dizal Pharmaceuticals

Completed

Pharmacokinetic and Mass Balance Study of Oral-Administrated [14C]-DZD9008 in Healthy Male Subjects

Healthy Volunteers

United States
Alexion Pharmaceuticals

Terminated

Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia

Pneumonia, Viral | Acute Respiratory Distress Syndrome | Acute Lung Injury | COVID-19 Severe Pneumonia

United States, Spain, United Kingdom, France, Japan
Constellation Pharmaceuticals

Completed

A Study Evaluating CPI-1205 in Patients With B-Cell Lymphomas

B-Cell Lymphoma

United States
CStone Pharmaceuticals

Completed

A Study of CS3005 in Advanced Solid Tumors

Advanced Solid Tumor

Australia
Regeneron Pharmaceuticals

Completed

COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection

COVID-19

United States
Novatek Pharmaceuticals

Completed

To Evaluate the Safety and Efficacy of TQ Formula in Covid-19 Participants (BOSS)

Covid19

United States
Arena Pharmaceuticals

Terminated

Safety, Tolerability, and Efficacy of Etrasimod (APD334) in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Australia, New Zealand
Rigel Pharmaceuticals

Enrolling by invitation

A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Warm Antibody Autoimmune Hemolytic Anemia

Spain, United States, Australia, Norway, Belarus, Germany, Netherlands, Belgium, Austria, Bulgaria, Czechia, France, Georgia, Italy, Russian Federation, Serbia, Ukraine, United Kingdom
Boston Pharmaceuticals

Completed

Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care

Systemic Lupus Erythematosus

United States, Philippines, Hungary, Poland, Mexico, Colombia, Ukraine, Peru, Romania, Argentina, Bulgaria, Georgia
Concert Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers

Healthy Volunteers

United States
Ferring Pharmaceuticals

Completed

A Trial to Investigate Efficacy, Safety and Tolerability of FE 201836 for Nocturia Due to Nocturnal Polyuria in Adults

Nocturia

United States, Belgium, Czechia, Hungary, Poland, Canada, Germany
Endo Pharmaceuticals

Completed

Real World CCH Study in Adult Females With Cellulite

Cellulite | Edematous Fibrosclerotic Panniculopathy (EFP)

United States, Puerto Rico
Veloxis Pharmaceuticals

Withdrawn

A Trial Measuring ART-123 Ability to Prevent Sensory Neuropathy in Unresectable mCRC Subjects w/Oxaliplatin-based Chemo

Chemotherapy-induced Peripheral Neuropathy
BioCryst Pharmaceuticals

Completed

First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria

United Kingdom, Austria, South Africa
Modra Pharmaceuticals

Withdrawn

Absorption and Excretion of Oral Docetaxel

Solid Tumor, Adult

Netherlands
ASLAN Pharmaceuticals

Completed

Varlitinib in Combination With mFOLFOX6 for Advanced or Metastatic Gastric Cancer (First Line)

Gastric Cancer

Estonia, Hong Kong, Korea, Republic of, Lithuania, Malaysia, Singapore, Taiwan, Thailand
Alexion Pharmaceuticals

Completed

Study of Subcutaneous and Intravenous ALXN1720 With and Without rHuPH20 in Healthy Subjects

Healthy

United Kingdom
Jazz Pharmaceuticals

Completed

An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Adults With Dravet or Lennox-Gastaut Syndromes (GWPCARE5)

Epilepsy | Dravet Syndrome | Lennox-Gastaut Syndrome
Aerie Pharmaceuticals

Completed

Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United Kingdom, Spain, Austria, Belgium, Czechia, France, Germany, Hungary, Italy, Latvia, Poland
Regeneron Pharmaceuticals

Completed

Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN10933+REGN10987) in Adult Volunteers as Related to COVID-19

Healthy | Chronic Stable Illness

United States
Cumberland Pharmaceuticals

Completed

Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patients

Liver Cirrhosis | Portal Hypertension

United States

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