Clinical Trials Sponsored by Vaccinex Inc.

Total 36306 results

Bharat Serums and Vaccines Limited
Ministry of Science and Technology

Completed

To Study the Effect Of Single Infusions Of Amphotericin B Lipid Preparations in Treatment of Patients Of Kala Azar

Leishmaniasis, Visceral

India
TD Vaccines A/S
Johns Hopkins University; University of Vermont; SNBL Clinical Pharmacology Center... and other collaborators

Unknown

ACE393-103 Vaccination Challenge Study (ACE393-103VC)

Campylobacter Infection

United States
Public Health Vaccines LLC
Biomedical Advanced Research and Development Authority

Recruiting

Study to Evaluate the Recombinant Vesicular Stomatitis Virus (rVSV)-Marburg Virus Vaccine Candidate (PHV01) in Healthy Adult Subjects (PHV01)

Marburg Virus Disease

United States
ANRS, Emerging Infectious Diseases
LinKinVax; Vaccine Research Institute (VRI), France

Not yet recruiting

Safety and Immunogenicity of a Sub-unit Protein CD40.RBDv Bivalent COVID-19 Vaccine, Adjuvanted or Not, as a Booster in Volunteers.

COVID-19
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College

Active, not recruiting

A Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021)

SARS-CoV-2

China
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI)

Terminated

Safety and Efficacy of NF135 CPS Immunization (CPS135)

Malaria,Falciparum | Controlled Human Malaria Infection | Immunization; Infection

Netherlands
AIM Vaccine Co., Ltd.
Shulan (Hangzhou) Hospital; Yuncheng Central Hospital

Active, not recruiting

Clinical Trial of SARS-CoV-2 mRNA Vaccine in China

COVID-19

China
International Vaccine Institute
Inovio Pharmaceuticals; Coalition for Epidemic Preparedness Innovations

Completed

Safety, Tolerability and Immunogenicity of INO-4800 Followed by Electroporation in Healthy Volunteers for COVID19

Coronavirus Infection | SARS-CoV 2

Korea, Republic of
International Centre for Diarrhoeal Disease Research...
Incepta Vaccine Limited

Completed

Non Inferiority Trial of Locally Manufactured Meningococcal ACWY Vaccine 'Ingovax ACWY' in Bangladesh.

Meningococcal Vaccine

Bangladesh
International Centre for Diarrhoeal Disease Research...
International Vaccine Institute

Completed

Safety and Immunogenicity of Locally Manufactured Oral Cholera Vaccine

Cholera

Bangladesh
Johns Hopkins Bloomberg School of Public Health
PATH Vaccine Solutions

Completed

Low-dose Challenge Model With Enterotoxigenic E Coli

Diarrhea

United States
International AIDS Vaccine Initiative
Biomedical Advanced Research and Development Authority

Active, not recruiting

Evaluation of Safety and Immunogenicity of rVSVΔG-SEBOV-GP Vaccine in Adults With Good General Health

Ebola Sudan Virus Disease

United States
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI)

Completed

Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31F (TB31F)

Malaria,Falciparum

Netherlands
Albert B. Sabin Vaccine Institute
ICON plc; Oklahoma Blood Institute

Completed

Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults

Ebola Virus Disease | Marburg Virus Disease

United States
GlaxoSmithKline
Crucell Holland BV; The PATH Malaria Vaccine Initiative (MVI)

Completed

Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults

Malaria

United States
Cardiff University
Juvenile Diabetes Research Foundation; Diabetes Vaccine Development Centre

Completed

Safety Study to Assess Whether Proinsulin Peptide Injections Can Slow or Stop the Body Damaging Its Own Insulin-making Cells in the Pancreas in Patients Newly Diagnosed With Type 1 Diabetes (MonoPepT1De)

Type 1 Diabetes

United Kingdom
Federal University of São Paulo
Albert B. Sabin Vaccine Institute

Completed

Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants

Pain | Analgesia | Neonatal Infections

Brazil
Institute of Vaccines and Medical Biologicals,...
Quintiles, Inc.; PATH; World Health Organization; Pasteur Institute, Ho Chi Minh...

Completed

Seasonal Trivalent Inactivated Split Virion Influenza Vaccine Clinical Trial (IVACFLU-S) - PHASE 2/3 (IVACFLUS-0203)

Influenza, Human

Vietnam
International AIDS Vaccine Initiative
Emory University; Fred Hutchinson Cancer Center; George Washington University; ModernaTX... and other collaborators

Active, not recruiting

A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core)

Hiv

United States
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.; AIM...

Recruiting

A Global Multi-center Clinical Study of SARS-CoV-2 mRNA Vaccine for the Prevention of COVID-19

SARS-CoV-2

Kenya
Objectif Recherche Vaccins SIDA
Fondation Bettencourt-Schueller

Completed

Towards HIV Functional Cure (ULTRASTOP)

Chronic HIV-1 Infection

France
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.; Oncoceutics, Inc.

Recruiting

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

Metastasis | Endometrial Cancer

United States
Janssen Vaccines & Prevention B.V.
Walter Reed Army Institute of Research (WRAIR)

Completed

Safety, Tolerability and Immunogenicity Study of 2-dose Heterologous Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-Filo

Hemorrhagic Fever, Ebola

United States, Uganda, Kenya, Mozambique, Nigeria, Tanzania
University of Vermont
Naval Medical Research Center; TD Vaccines A/S

Unknown

Campylobacter Jejuni Challenge Model Development: Dose Ranging Study

Campylobacter Infections

United States
NC Medial Research Inc

Recruiting

A Study of NCS-01 in Patients With Acute Ischemic Stroke

Ischemic Stroke

United States
Malaria Vaccine and Drug Development Center
Fundacion Clinica Valle del Lili

Completed

Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers

MALARIA | Chills | FEVER | ANEMIA | Sweating Fever

Colombia
International AIDS Vaccine Initiative
University of Nairobi; Medical Research Council-Oxford

Completed

A Phase IIA Trial to Evaluate the Safety and Immunogenicity of a DNA HIV-1 Vaccine Followed by an MVA HIV-1 Vaccine in HIV-uninfected Volunteers

HIV Infections

United Kingdom, Kenya
Seattle Children's Research Institute (SCRI)
The PATH Malaria Vaccine Initiative (MVI)

Completed

Reproducibility of Malaria Challenge in Healthy Volunteers

Healthy

United States
Albert B. Sabin Vaccine Institute
Biomedical Advanced Research and Development Authority

Not yet recruiting

Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults

Ebola Sudan Virus Disease

Uganda, Kenya
MRC/UVRI and LSHTM Uganda Research Unit
International AIDS Vaccine Initiative

Recruiting

Feasibility of Identifying, Enrolling and Following Acute and Early HIV-1 Infected Individuals. (KILGORIS)

Acute Human Immunodeficiency Virus Type I Infection

Uganda
Albert B. Sabin Vaccine Institute
Biomedical Advanced Research and Development Authority

Active, not recruiting

Monovalent Chimpanzee Adenoviral-Vectored Marburg Virus Vaccine in Healthy Adults

Marburg Virus Disease

Uganda, Kenya
University of Toronto
UVRI-IAVI HIV Vaccine Program; Entebbe General Hospital

Unknown

Effect of Antibiotics on Penile Microbiome and HIV Susceptibility Study in Ugandan Men

Foreskin HIV Susceptibility

Uganda
IC-IT Sciences Inc.

Unknown

Comparison of the Natural Frequencies Technology Sleep Patches to Sham Patches During Sleep in the Home Environment

Sleep Disturbance

United States
Emory University
International AIDS Vaccine Initiative; Zambia-Emory HIV Research Project

Completed

Zambia SiVET MMR Tdap-IPV (SiVET)

High Risk for HIV

Zambia
International Vaccine Institute
Christian Medical College, Vellore, India; Shantha Biotechnics Limited

Completed

A Study to Evaluate Safety and Immunogenicity of the Bivalent Killed Whole Cell Oral Cholera Vaccine in Adults and Children

Vibrio Cholerae

India
University of Wisconsin, Madison
Bristol-Myers Squibb; National Cancer Institute (NCI); United States Department... and other collaborators

Recruiting

Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer

Prostate Cancer

United States
Chulalongkorn University
National Vaccine Institute, Thailand; Chula Vaccine Research Center (ChulaVRC)... and other collaborators

Completed

ChulaCov19 Vaccine in Healthy Adults

COVID-19 Vaccine | Safety Issues

Thailand
Zhengzhou Gensciences Inc
Haimen Gensciences lnc

Completed

An Open Label Study to Determine the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A.

Hemophilia A

China
Zhengzhou Gensciences Inc
Jiangsu Gensciences lnc.

Completed

Phase III Expansion Trial for Determining the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A (RH-107-III02)

Hemophilia A

China
Bandim Health Project
Research Center for Vitamins and Vaccines, Statens Serum Institute

Terminated

Can Earlier BCG Vaccination Reduce Early Infant Mortality? A Randomised Trial (BCGR)

Infant Mortality | BCG

Guinea-Bissau
MCM Vaccines B.V.
Merck Sharp & Dohme LLC; Sanofi Pasteur, a Sanofi Company

Completed

Long-term Persistence of Hepatitis B and Pertussis Antibody Responses in Healthy 4 to 5 Year Old Children Previously Vaccinated With Vaxelis® or INFANRIX® Hexa (V419-012)

Hepatitis B | Pertussis
St George's, University of London
Novartis Vaccines; European Union; Richmond Pharmacology Limited

Terminated

Safety Study Of Nasal HIV Vaccine Adjuvanted With LTK63

HIV Infections

United Kingdom
University of Maryland, Baltimore
Bill and Melinda Gates Foundation; Auro Vaccines LLC

Completed

A Safety and Immunogenicity Trial of IHV01 (FLSC-001)

HIV Infection

United States
Bandim Health Project
Statens Serum Institut; Research Center for Vitamins and Vaccines

Unknown

Vaccine Campaign Effects on General Hospital Admissions and Mortality Among Children (RE-CAMP)

Mortality | Children | Oral Polio Vaccine | Morbidity | Measles Vaccination | Non-specific/Heterologous Effects of Vaccines

Guinea-Bissau
Dalhousie University
Mount Sinai Hospital, Canada; IWK Health Centre; MCM Vaccines B.V.

Completed

Study to Compare Self-administered and Nurse-administered Intradermal Influenza Vaccine

Influenza

Canada
St George's, University of London
Novartis Vaccines; Statens Serum Institut; European Union

Terminated

A Phase I Trial of a LTK63 Adjuvated Tuberculosis Nasal Subunit Vaccine (Ag85B-ESAT6) (TMUVA-01)

Tuberculosis

United Kingdom
MCM Vaccines B.V.
Merck Sharp & Dohme LLC; Sanofi Pasteur, a Sanofi Company

Completed

Spanish Mixed HEXA/PENTA/HEXA Schedule (V419-010)

Virus Diseases | Bacterial Infections | Neisseria Meningitidis
Janssen Vaccines & Prevention B.V.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study to Evaluate Safety, Tolerability, and Immunogenicity of Heterologous Prime-boost Regimens Using the Multivalent Filovirus Vaccines Ad26.Filo and MVA-BN-Filo Administered in Different Sequences and Schedules in Healthy Adults

Healthy

United States
Swedish Institute for Infectious Disease Control
MCM Vaccines B.V.; Statens Serum Institut

Unknown

An Immunogenicity and Safety Study of Tetanus, Diphtheria and Acellular Pertussis Vaccine Booster (Tdap Booster)

Pertussis | Tetanus | Diphtheria

Sweden
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Evaluating the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibodies in Healthy Participants (HVTN143)

HIV Infections

South Africa

Clinical Trials Sponsored by Vaccinex Inc.

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