Search clinical trials for: Genetic Disease

Total 383883 results

IRCCS San Raffaele
Università Vita-Salute San Raffaele

Recruiting

Mechanisms of Somatic Mutation and Tumor Initiation in Pre-malignant Kidney Tubule Cells (SoMuKT)

Carcinoma, Renal Cell | Von Hippel-Lindau Disease

Italy
AstraZeneca

Not yet recruiting

LTFU for All Cell and Gene Therapy Studies (LOCUS)

Hepatocellular Carcinoma | Prostate Cancer

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Long Term Follow-up Grafted Huntington's Disease Patients (Post-MIGHD)

Huntington Disease

France
Møreforsking AS
University of Manchester; Helse Møre og Romsdal HF; Epax Norway AS

Recruiting

Nutritional Study to Determine the Effect of Fish Oil on Atopic Dermatitis (CetoSkin)

Atopic Dermatitis

Norway
IRCCS San Raffaele

Recruiting

Overtaking Intra and Inter Tumoral Heterogeneity In Von Hippel-Lindau Related Renal Cancer (ITHORinVHL)

Clear Cell Renal Cell Carcinoma | VHL Syndrome

Italy
Mirum Pharmaceuticals, Inc.

Recruiting

Long-Term Safety and Clinical Outcomes of Livmarli in Patients With Alagille Syndrome (LEAP) (LEAP)

Alagille Syndrome

United States
University of California, Los Angeles
University of Iowa; Children's Hospital Colorado; University of Kansas Medical... and other collaborators

Recruiting

Sinus Disease in Young Children With Cystic Fibrosis

Chronic Rhinosinusitis (Diagnosis) | Cystic Fibrosis | Olfactory Disorder | Cystic Fibrosis in Children | Olfactory Impairment

United States
Sanofi

Recruiting

A Study to Observe How Adolescent Patients With Severe Atopic Dermatitis Despite Less Extensive Skin Lesions (Eczema Area and Severity Index Score < 16) Respond to Dupilumab Treatment (AD-BEASCUITS)

Dermatitis Atopic

Italy
Sanofi
Pulse Infoframe Ltd.

Recruiting

A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

Niemann-Pick Diseases | Acid Sphingomyelinase Deficiency

United States
The Hospital for Sick Children
Roche Pharma AG

Not yet recruiting

Canadian CHO-KLAT/H-FIT Study - Quality of Life of, and Burden of Caring for, Persons With Hemophilia

Hemophilia
Quince Therapeutics S.p.A.
Biotrial

Not yet recruiting

To Evaluate the Effects of EryDex in Patients With A-T (NEAT)

Ataxia Telangiectasia

Belgium, United States, Denmark, Germany, Italy, Norway, Poland, Spain, United Kingdom
Qianfoshan Hospital

Not yet recruiting

Correlation Between Psychological Resilience and Genetic, Inflammatory Indicators

Inflammation | Genetic Predisposition to Disease | Adaptation, Psychological | Environment
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of IBI356 in Healthy Participants and in Atopic Dermatitis Patients

Healthy Participants | Atopic Dermatitis Patients

China
Mario Negri Institute for Pharmacological Research

Recruiting

Outcome of ADPKD With Octreotide LAR (ADPKD648)

Autosomal Dominant Polycystic Kidney

Italy
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Recruiting

Longitudinal Prospective Natural History Study of Retinopathy in Zellweger Spectrum Disorder (ZSDvision)

Zellweger Spectrum Disorder

Canada
Istituto Ortopedico Rizzoli

Recruiting

Increasing Knowledge on Osteogenesis Imperfecta by Collecting Epidemiological Data (4FRAILTY)

Osteogenesis Imperfecta

Italy
Kun Sun

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of SKG0201 Injection in Patients With Spinal Muscular Atrophy Type 1

Spinal Muscular Atrophy 1

China
University of Alabama at Birmingham
Children's Hospital of Philadelphia; Congressionally Directed Medical Research...

Not yet recruiting

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1 (NF114)

Neurofibromatosis 1 | Plexiform Neurofibroma
University of California, Los Angeles
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

UR+AIMS Gout Wearable Skin Uric Acid Monitor Study

Gout

United States
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
Biocad

Recruiting

A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A (EDELWEISS)

Hemophilia A

Russian Federation
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1) (Galileo)

Myotonic Dystrophy Type 1 (DM1)

United Kingdom, Canada, Australia
Rutgers, The State University of New Jersey

Recruiting

Choices About Genetic Testing And Learning Your Risk With Smart Technology (CATALYST)

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Prostate Cancer | Endometrial Cancer | Pancreas Cancer | Peritoneal Cancer

United States
Chiesi Farmaceutici S.p.A.

Not yet recruiting

Analysis of Velmanase Alfa (Lamzede®)'s Effects in the Body of Children With Alpha-Mannosidosis Under the Age 3 (LAMPO(0-3))

Alpha-Mannosidosis
University of Maryland, Baltimore

Not yet recruiting

Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

Acute Pain | Sickle Cell Disease | Vaso-occlusive Pain Episode in Sickle Cell Disease

United States
St. Justine's Hospital

Not yet recruiting

Virtual Reality for Pain Management During Dupilumab Injection (VR-DERMA)

Pain | Anxiety | Atopic Dermatitis

Canada
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Multicenter Analysis of Genomic and Metabolic Data of Neonatal Genetic Diseases (MAOFGAMDNGD)

Hereditary Diseases

China
University Hospital, Strasbourg, France

Recruiting

Interference by Activated Protein C Resistance in the Determination of Protein S Activity (PS)

Resistance to Activated Protein C in the Determination of Protein S Activity

France
University of Nicosia
Cyprus Institute of Neurology and Genetics

Recruiting

Probiotics in Mild Alzheimer's Disease

Neurodegenerative Diseases | Cognition Disorders in Old Age

Cyprus
Denali Therapeutics Inc.

Recruiting

Study of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA (Sanfilippo Syndrome Type A)

Mucopolysaccharidosis Type IIIA

United States
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

Dermatitis Atopic

Argentina, Japan, China, Czechia, Spain, United States, South Africa, United Kingdom, Denmark, Sweden, Turkey
Viridian Therapeutics, Inc.

Recruiting

An Open-label Study for Participants Who Are Non-responders at the End of Treatment Assessment on the VRDN-001-101 and VRDN-001-301 Pivotal Studies

Thyroid Eye Disease

United States
University of Washington
Breast Cancer Research Foundation

Not yet recruiting

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic HER2-Negative Breast Carcinoma | Metastatic Hormone Receptor-Positive Breast Carcinoma | Locally Advanced Unresectable HER2-Negative Breast Carcinoma | Locally Advanced Unresectable Hormone Receptor-Positive...

United States
Huashan Hospital

Not yet recruiting

Evaluation of the Safety, Tolerability and Efficacy of Gene Therapy Drug for Late Onset Pompe Disease (LOPD)

Pompe Disease (Late-onset)

China
Assiut University

Not yet recruiting

Evaluation of Cognitive Dysfunction and Psychiatric Comorbidities

Wilson Disease
Azienda Ospedaliero-Universitaria di Modena

Recruiting

Role of Cardiac AngioMR in Diagnosis of Cardiac and Vascular Anomalies in Adult Patients With Turner Syndrome

Turner Syndrome | Anomaly Heart

Italy
ETH Zurich
University of Zurich; Agroscope Liebefeld-Posieux Research Station ALP; Swiss...

Recruiting

Lactobreath: A Study to Diagnose Lactose Intolerance Using Breath Markers (Lactobreath)

Lactose Intolerance

Switzerland
Columbia University

Not yet recruiting

Impact of Exercise on Eyeblink Conditioning in Spinocerebellar Ataxias

Spinocerebellar Ataxias

United States
St. Joseph's Hospital and Medical Center, Phoenix
Texas Tech University

Not yet recruiting

MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Cognitive Dysfunction | Neurodegenerative Disease, Hereditary | Cognitive Impairment, Mild | Amyloid Plaque | Inflammation, Brain
Minoryx Therapeutics, S.L.

Recruiting

Disease Progression in Women With X-linked Adrenoleukodystrophy

X-linked Adrenoleukodystrophy

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study of the Blood and Skin Immunological Profile of Patients With Recessive Dystrophic Epidermolysis Bullosa: in Vivo Analysis and the Impact of Placental Stem Cells in Vitro (ISTRADEB)

Epidermolysis Bullosa Dystrophica
Tavotek Biotherapeutics

Recruiting

A Study of TAVO101 in Atopic Dermatitis Patients

Atopic Dermatitis

New Zealand
AstraZeneca

Recruiting

Observational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNs (PEDIA)

Neurofibroma, Plexiform

China
University Hospital, Ghent

Not yet recruiting

PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study

Quality of Life | Ovarian Stimulation | Preimplantation Genetic Testing | Fertility Preservation
Power Life Sciences Inc.

Not yet recruiting

Investigating Participation Patterns of Patients in Atopic Dermatitis Clinical Trials

Atopic Dermatitis

United States
Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR); Population Health Research Institute and other collaborators

Not yet recruiting

Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy (TaRGET)

Arrhythmogenic Right Ventricular Cardiomyopathy | Arrhythmogenic Cardiomyopathy

Canada
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of GR2002 Injection in Patients With Atopic Dermatitis.

Atopic Dermatitis

China
Sun Yat-sen University

Not yet recruiting

The Effect of Sodium Fluoride Application on the Prevention of Radiation Caries in NPC Patients

Sodium Fluoride
Hacettepe University

Recruiting

Assessment of Cognitive Function and Exercise Capacity in Cystic Fibrosis

Cystic Fibrosis

Turkey

Search clinical trials for: Genetic Disease

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