Search clinical trials for: evaluate putative environmental exposures and NPC

Total 472731 results

Incyte Corporation

Recruiting

A Study to Evaluate the Safety and Tolerability of Maximal Use Ruxolitinib Cream

Prurigo Nodularis

United States
Incyte Corporation

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult Participant

Healthy Participants

Australia
Peking University Cancer Hospital & Institute

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Immunotherapy With Axitinib in Advanced Collecting Duct Carcinoma

Collecting Duct Carcinoma

China
Spanish Cooperative Group for the Treatment of...
Merck, S.L., Spain; Pierre Fabre Ibérica, S.A.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Cetuximab in Combination With Encorafenib Plus Binimetinib as Induction Treatment in BRAF V600E Mutated MSS Initially Resectable or Potentially Resectable Advanced Colorectal Cancer (CEBBRA)

Colorectal Cancer
RenJi Hospital
Shanghai Simnova Biotechnology Co.,Ltd.

Recruiting

F01 in the Treatment of Autoimmune Diseases

Autoimmune Diseases

China
Shanghai Simnova Biotechnology Co.,Ltd.
Wuhan Union Hospital, China

Recruiting

F01 in the Treatment of Relapsed/Refractory Non-hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

China
Huons Biopharma

Not yet recruiting

To Evaluate HU-045 in the Treatment of Glabellar Lines(Phase III)

Glabellar Lines
Jair Bar, M.D., Ph.D.

Not yet recruiting

Neo-Bio-ADAURA: A Phase II Study to Evaluate Mechanisms of Resistance to Neoadjuvant Osimertinib

Non-squamous NSCLC
Kyowa Kirin Korea Co., Ltd.

Recruiting

Multicenter, Open, Prospective, 48 Weeks, Observational Study ,Evaluate the Safety and Efficacy of Nephoxil Capsule

Hyperphosphatemia

Korea, Republic of
University School of Physical Education, Krakow...
Ministry of Education and Science,Poland

Recruiting

The Impact of Physical Training Under Normobaric Hypoxia on Oxidative Stress Level, Inflammatory State, Intestinal Damage, and Mitochondrial Metabolism in Young Males

Hypoxia, Altitude

Poland
Inge Marie Svane
Adaptimmune

Not yet recruiting

To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma (ADP-TILIL7)

Melanoma | Melanoma Stage IV | Melanoma Stage III
Ahon Pharmaceutical Co., Ltd.

Recruiting

A Trial to Evaluate the Efficacy and Safety of Methoxyetomidate Hydrochloride for Injection (ET-26) for the Induction of General Anesthesia in Elective Surgery Subjects

Anesthesia Induction

China
Retropsoas Technologies, LLC

Not yet recruiting

A Post-marketing Study to Evaluate a Novel Surgical Monitoring Technique Using the EARP Nerve Cuff in TLIF Surgery.

Undergoing a Single-level or Two-level TLIF Surgery

United States
Hospital Universitario Central de Asturias

Recruiting

Prospective, Single-Arm, Multicenter Study to Evaluate the Effectiveness and Safety of Endovascular Treatment in Patients With Cerebral Aneurysms Using P64 and P48 Flow-Diverter Stents (pSPAIN_HPC)

Cerebral Aneurysm | Thromboembolic Disease

Spain
Candela Corporation

Recruiting

Clinical Study to Evaluate the Safety and Efficacy of Candela Technology

Scars | Acne | Wrinkle | Tattoo Removal | Skin Conditions | Hair Reduction | Benign Cutaneous Vascular Lesions

United States, Israel
Huashan Hospital

Recruiting

A Study to Evaluate the Human Biodistribution and Dosimetry of the Radionuclide Labeled ZT-111 in Patients With Metastatic Prostate Cancer

Prostate Specific Membrane Antigen Positive Metastatic Prostate Cancer

China
JHM BioPharma (Tonghua) Co. , Ltd.

Recruiting

A Phase I/II, Randomized, Double-blind, Placebo, and Active Controlled Clinical Study to Evaluate the Safety, Tolerability, Immunogenicity, and Preliminary Efficacy of JHM03 in Subjects With Moderate to Severe Glabellar Lines

Moderate to Severe Glabellar Lines

China
Forma Therapeutics, Inc.
Novo Nordisk A/S

Recruiting

A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

Sickle Cell Disease

Lebanon, Canada, Kenya, United Kingdom
Mabwell (Shanghai) Bioscience Co., Ltd.

Not yet recruiting

A Study to Evaluate 9MW2821 Versus Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer

Advanced Urothelial Carcinoma

China
Sun Yat-sen University

Not yet recruiting

Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for r/m NPC

Nasopharyngeal Carcinoma | Recurrent and Metastatic Nasopharyngeal Carcinoma | Multi-omics Technique | Efficacy of Chemoradiotherapy and Immunotherapy

China
International Centre for Diarrhoeal Disease Research...
Bill and Melinda Gates Foundation

Recruiting

Maternal Probiotic Intervention to Improve Gut Health (MPIGH)

Environmental Enteric Dysfunction | Gut Microbiota Dysbiosis

Bangladesh
University of Manitoba

Recruiting

Exercise Testing in ICU Survivors to Evaluate ICU-acquired Weakness

Sepsis | Shock | ICU Acquired Weakness | Microvascular Dysfunction

Canada
AstraZeneca

Recruiting

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Transthyretin Amyloid Cardiomyopathy

China
AstraZeneca

Recruiting

To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations (NEOLA)

Lung Cancer

Spain, Vietnam, China, India, Taiwan, Thailand, Israel, Turkey, United States, Korea, Republic of
Hanoi Medical University

Recruiting

Evaluate the Effectiveness of Progestin-Primed Versus GnRH Antagonist Protocols in Vietnamese Women Undergoing In-vitro Fertilization

IVF

Vietnam
Quince Therapeutics S.p.A.
Biotrial

Not yet recruiting

To Evaluate the Effects of EryDex in Patients With A-T (NEAT)

Ataxia Telangiectasia

Belgium, United States, Denmark, Germany, Italy, Norway, Poland, Spain, United Kingdom
Amsterdam University of Applied Sciences

Not yet recruiting

Environmentally Sustainable Nutrition for Older Adults (55+) With Obesity (2EAT)

Obesity | Aging
Ascletis Pharmaceuticals Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Efficacy of ASC40 (Denifanstat) Tablets in the Treatment of Patients With Moderate to Severe Acne Vulgaris

Acne

China
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Recruiting

Clinical Study to Evaluate Cannabidiol Liver Enzyme Elevations and Drug Interactions

Drug Interaction | Drug Induced Liver Injury | Cannabidiol

United States
selectION Therapeutics GmbH
FGK Clinical Research GmbH

Recruiting

A Study to Evaluate the Safety and Tolerability, and the Efficacy of Si-544 in Adults With Psoriasis Vulgaris or Psoriatic Arthritis

Psoriasis Vulgaris | Psoriatic Arthritis

Germany
University Hospital of Limerick

Not yet recruiting

Effect of Environmental Temperature on Vascular Ultrasound Vein Scan Measurements

Critical Limb Ischemia
Curon Biopharmaceutical (Shanghai) Co.,Ltd

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CN201

Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

China
Changchun GeneScience Pharmaceutical Co., Ltd.
West China Hospital

Not yet recruiting

A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease

Systemic Sclerosis Associated Interstitial Lung Disease | Rheumatoid Arthritis Associated Interstitial Lung Disease (RA-ILD) | Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)

China
Jiangsu ProteLight Pharmaceutical & Biotechnology...
Parexel

Not yet recruiting

Phase II Study to Evaluate Efficacy and Safety of AMP Peptide PL-5 in Mild Infections of Diabetic Foot Ulcers (PL-5)

Diabetic Foot Ulcers

United States
Kariya Pharmaceuticals

Not yet recruiting

Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients

Tolerance | Safety Issues
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate Efficacy of Dietary Ingredient in Vitality and Metabolic Factors in Healthy Individuals

Aging

India
GlaxoSmithKline

Not yet recruiting

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants

Systemic Lupus Erythematosus

United Kingdom
AstraZeneca

Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors (CYCAD-1)

ER+ HER2- Advanced Breast Cancer | High-grade Serous Ovarian Cancer (HGSOC)

United Kingdom, Korea, Republic of, Australia, United States, Spain
Vividion Therapeutics, Inc.

Recruiting

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

Advanced Solid Tumors | Advanced Hematologic Tumors

United States, Australia
Korea University Anam Hospital

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Rivaroxaban 15mg and 20mg in Patients With Non-valvular Atrial Fibrillation (REVISE-AF)

Atrial Fibrillation | Anticoagulant Adverse Reaction

Korea, Republic of
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
NeuroSense Therapeutics Ltd.

Recruiting

A Phase 2, Randomized, Prospective Double-Blind, Single-Center, Placebo-controlled Study to Evaluate Safety, Tolerability, Target Engagement, and Efficacy of PrimeC in Patients With Mild to Moderate Alzheimer's Disease. (RoAD)

Alzheimer Disease

Israel
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
University of Virginia
University of North Carolina

Recruiting

iSIPsmarter: A Pilot RCT to Evaluate a Web-based Behavioral Intervention to Reduce Sugary Beverages Among Black Adults

Diet Habit | Sugar-Sweetened Beverages

United States
National Atomic Research Institute, Taiwan

Not yet recruiting

A Study of Ga-68 Dolacga to Evaluate Liver Reserve Function in Patients With HCC Before and After Proton Therapy

Hepatic Carcinoma

Taiwan
Jiangxi Provincial Cancer Hospital

Recruiting

The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC

Nasopharyngeal Carcinoma | Tumor Microenvironment | Pathologic Complete Response

China
Wuhan Union Hospital, China

Recruiting

Evaluate the Effect of Prone Ventilation on Ventilated-blood Flow Ratio in Patients With ARDS by EIT

Acute Respiratory Distress Syndrome | Ventilation Perfusion Mismatch | Electrical Impedance Tomography | Prone Position Ventilation

China
Ruijin Hospital

Recruiting

A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Urological Surgeries (SPiM-RWS-URO)

Urological Surgeries

China
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

Dermatitis Atopic

Argentina, Japan, China, Czechia, Spain, United States, South Africa, United Kingdom, Denmark, Sweden, Turkey
Incyte Corporation

Recruiting

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Solid Tumors

United States, France, Italy, Australia, Spain, Canada, Belgium

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